Neuronal VEGF expression correlates with angiogenesis in postnatal developing rat brain

Developmental Brain Research

Volumn 119, Issue 1, 2000, Pages 139-153

  Ogunshola, Omolara O ^a   Stewart, William B ^a   Mihalcik, Vera ^a   Solli, Todd ^a   Madri, Joseph A ^a   Ment, Laura R ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiogenesis; Glia; Hypoxia; Neuron; Stabilization; Vascular endothelial growth factor

Indexed keywords

CD31 ANTIGEN; PROTEIN; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; CONTROLLED STUDY; GLIA CELL; HYPOXIA; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NERVE CELL; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD31; CELL COUNT; CEREBRAL CORTEX; CHRONIC DISEASE; ENDOTHELIAL GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLIAL FIBRILLARY ACIDIC PROTEIN; HYPOXIA, BRAIN; LYMPHOKINES; MICROCIRCULATION; NEOVASCULARIZATION, PHYSIOLOGIC; NEUROGLIA; NEURONS; RATS; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0033970896     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(99)00125-X     Document Type: Article

References (44)

1. Alon T., Hemo I., Itin A., Pe'er J., Stone J., Keshet E. Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat. Med. 1:1995;1024-1028.
2. Als H., Lawhon G., Brown E.E.A. Individualized behavioral and environmental care for the very low birth weight preterm infant at high risk for BPD: neonatal intensive care unit and developmental outcome. Pediatrics. 78:1986;1123-1132.
3. Augustin H.G., Braun K., Telemenakis I., Modlich U., Kuhn W. Ovarian angiogenesis. Phenotypic characterization of endothelial cells in a physiological model of blood vessel growth and regression. Am. J. Pathol. 147:1995;339-351.
4. Bregman J., Farrell E.E. Neurodevelopmental outcome in infants with bronchopulmonary dysplasia. Clin. Perinatol. 19:1992;673-694.
5. Breier G., Albrecht U., Sterrer S., Risau W. Expression of VEGF during embryonic angiogenesis and endothelial cell differentiation. Development. 114:1992;521-532.
6. Breier G., Breviario F., Caveda L., Berthier R., Schnurch H., Gotsch U., Vestwever D., Risau W., Dejana E. Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system. Blood. 87:1996;630-641.
7. Brogi E., Wu T., Namiki A., Isner J.M. Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression only. Circulation. 90:1994;649-652.
8. Brown L.F., Berse B., Jackman R.W., Tognazzi K., Manseau E.J., Senger D.R., Dvorak H.F. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res. 53:1993;4727-4735.
9. Dobbing J. Undernutrition and the developing brain: the use of animal models to elucidate the human problem. Psychiatr., Neurol., Neurochir. 74:1971;422-433.
10. Drake C.J., Little C.D. Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization. Dev. Biol. 92:1995;7657-7661.
11. Ferrara N., Davis-Smyth T. The biology of vascular endothelial growth factor. Endocrine Reviews. 18:1997;4-25.
12. Ferrer I., Bernet E., Soriano E., Del R.T., Fonseca M. Naturally occurring cell death in the cerebral cortex of the rat and removal of dead cells by transitory phagocytes. Neuroscience. 39:1990;451-458.
13. Flamme I., von Reutern M., Drexler H.C.A., Syed-Ali S., Risau W. Overexpression of vascular endothelial growth factor in the avian embryo induces hypervascularization and increased permeability without alterations of embryonic pattern formation. Dev. Biol. 171:1995;399-414.
14. Graesser D., Mahooti S., Haas T., Davis S., Clark R.B., Madri J.A. The interrelationship of alpha4 integrin and matrix metalloproteinase-2 in the pathogenesis of experimental autoimmune encephalomyelitis. Lab. Invest. 78:1998;1445-1458.
15. Gumina R.J., El Schultz J., Yao Z., Warltier D.C., Newman P.J., Gross G.J. Antibody to platelet/endothelial cell adhesion molecule-1 reduces myocardial infarct size in a rat model of ischemia-reperfusion injury. Circulation. 94:1996;3327-3333.
16. Hack M., Taylor H.G., Kelin N., Eiben R., Schatschneider C., Mercuri-Minich N. School-age outcomes in children with birth weights under 750 g. N. Engl. J. Med. 331:1994;753-759.
17. S.I. Harik, M.A. Hritz, J.C. LaManna, Hypoxia-induced brain angiogenesis in the adult rat, J. Physiol. (London) (1995).
18. Hayashi T., Abe K., Suzuki H., Itoyama Y. Rapid induction of vascular endothelial growth factor gene expression after transient middle cerebral artery occlusion in rats. Stroke. 28:1997;2039-2044.
19. Ijichi A., Sakuman S., Tofilon P.J. Hypoxia-induced vascular endothelial growth factor expression in normal rat astrocyte cultures. Glia. 14:1995;87-93.
20. Ilan N., Mahooti S., Madri J.A. Distinct signal transduction pathways are utilized during the tube formation and survival phases of in vitro angiogenesis. Journal of Cell Science. 111:1998;3621-3631.
21. Ilan N., Mahooti S., Rimm D.L., Madri J.A. PECAM-1 (CD31) functions as a reservoir for and a modulator of tyrosine-phosphorylated β-catenin. Journal of Cell science. 112:1999;3005-3014.
22. Issa R., Krupinski J., Bujny T., Kuman S., Kaluza J., Kuman P. Vascular endothelial growth factor and its receptor, KDR, in human brain tissue after ischemic stroke. Lab. Invest. 79:1999;417-425.
23. Jakeman L.B., Armanini M., Phillips H.S., Ferrara N. Developmental expression of binding sites and messenger ribonuceic acid for vascular endothelial growth factor suggests a role for this protein in vasculogenesis and angiogenesis. Endocrinology. 133:1993;848-859.
24. Kuo N.T., Benhayon D., Przybylski R.J., Martin R.J., LaManna J.C. Prolonged hypoxia increases vascular endothelial growth factor mRNA and protein in adult mouse brain. J. Appl. Physiol. 86:1999;260-264.
25. LaManna J.C., Vendel L.M., Farrell R.M. Brain adaptation to chronic hypobaric hypoxia in rats. J. Appl. Physiol. 72:1992;2238-2243.
26. Leung D.W., Cachianes G., Kuang W.-J., Goeddel D.V., Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science. 246:1989;1306-1309.
27. Luchi J.M., Bennett F.C., Jackson J.C. Predictors of neurodevelopmental outcome following bronchopulmonary dysplasia. AJDC. 145:1991;813-817.
28. Marti H.H., Risau W. Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors. Proc. Natl. Acad. Sci. U.S.A. 95:1998;15809-15814.
29. Ment L.R., Schwartz M., Makuch R.W., Stewart W.B. Association of chronic sublethal hypoxia with ventriculomegaly in the developing rat brain. Dev. Brain Res. 111:1998.
30. Ment L.R., Stewert W.B., Fronc R., Seashore C., Mahooti S., Scaramuzzino D., Madri J.A. Vascular endothelial growth factor mediates reactive angiogenesis in the developing brain. Dev. Brain Res. 100:1997;52-61.
31. Minchenko A., Bauer T., Salcedo S., Caro J. Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo. Lab. Invest. 71:1994;374-379.
32. Mito T., Konomi H., Houdou S., Takashima S. Immunohistochemical study of the vasculature in the developing brain. Pediatr. Neurol. 7:1991;18-22.
33. Newman P.J. The biology of PECAM-1. J. Clin. Invest. 99:1997;3-8.
34. Newman P.J. Switched at birth: a new family for PECAM-1. J. Clin. Invest. 103:1999;5-9.
35. Plate K.H., Breier G., Weich H.A., Risau W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature. 350:1992;845-848.
36. Robertson P.L., DuBois M., Bowman P.D., Goldstein G.W. Angiogenesis in developing rat brain: an in vivo and in vitro study. Brain Res. 335:1985;219-223.
37. L. Rorke, Pathology of perinatal brain injury. Raven Press, New York, 1982, pp. 4-12.
38. Shweiki D., Itin A., Soffer D., Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature. 359:1992;843-845.
39. Stewart P.A., Isaacs H., LaManna J.C., Harik S.I. Ultrastructural concomitants of hypoxia-induced angiogenesis. Acta Neuropathol. (Berlin). 93:1997;579-584.
40. Stone J., Itin A., Alon T., Pe'er J., Gnessin H., Chan-Ling T., Keshet E. Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia. J. Neurosci. 15:1995;4738-4747.
41. Teborg A.J., Pena L.I., Finellp K., Aquillar T., Hodgman J.E. Prediction of neurodevelopmental outcome in infants with and without bronchopulmonary dysplasia. Am. J. Med. Sci. 301:1991;369-374.
42. Volpe J.J. Brain injury in the premature infant. Pediatr. Res. 27:1990;S28-S33.
43. Whitaker A.G., Feldman J.F., Rossem R.V., Schofeld I.S., Pinto-Martin J.A., Torre C., Blumenthal S.R., Paneth N.S. Neonatal cranial ultrasound abnormalities in low birth weight infants: relation to cognitive outcomes at six years of age. Pediatrics. 98:1996;719-729.
44. Xu F., Severinghaus J.W. Rat brain VEGF expression in alveolar hypoxia: possible role in high-altitude cerebral edema. J. Appl. Physiol. 85:1998;53-57.