메뉴 건너뛰기




Volumn 22, Issue 15, 2002, Pages 6537-6548

Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS

Author keywords

Amyotrophic lateral sclerosis; C Met; Caspase 1; EAAT2; HGF; Motoneuron

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; GLUTAMATE TRANSPORTER; INTERLEUKIN 1BETA CONVERTING ENZYME; NITRIC OXIDE SYNTHASE; SCATTER FACTOR;

EID: 0036703771     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-15-06537.2002     Document Type: Article
Times cited : (153)

References (48)
  • 1
    • 0033856830 scopus 로고    scopus 로고
    • Recent advances in amyotrophic lateral sclerosis
    • Al-Chalabi A, Leigh PN (2000) Recent advances in amyotrophic lateral sclerosis. Curr Opin Neurol 13:397-405.
    • (2000) Curr Opin Neurol , vol.13 , pp. 397-405
    • Al-Chalabi, A.1    Leigh, P.N.2
  • 4
    • 0032102110 scopus 로고    scopus 로고
    • The role of neuronal growth factors in neurodegenerative disorders of the human brain
    • Connor B, Dragunow M (1998) The role of neuronal growth factors in neurodegenerative disorders of the human brain. Brain Res Brain Res Rev 27:1-39.
    • (1998) Brain Res Brain Res Rev , vol.27 , pp. 1-39
    • Connor, B.1    Dragunow, M.2
  • 8
    • 0034811891 scopus 로고    scopus 로고
    • Identification of HGF-like protein as a novel neurotrophic factor for avian dorsal root ganglion sensory neurons
    • Funakoshi H, Nakamura T (2001) Identification of HGF-like protein as a novel neurotrophic factor for avian dorsal root ganglion sensory neurons. Biochem Biophys Res Commun 283:606-612.
    • (2001) Biochem Biophys Res Commun , vol.283 , pp. 606-612
    • Funakoshi, H.1    Nakamura, T.2
  • 9
    • 0027360908 scopus 로고
    • Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve
    • Funakoshi H, Frisen J, Barbany G, Timmusk T, Zachrisson O, Verge VM, Persson H (1993) Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve. J Cell Biol 123:455-465.
    • (1993) J Cell Biol , vol.123 , pp. 455-465
    • Funakoshi, H.1    Frisen, J.2    Barbany, G.3    Timmusk, T.4    Zachrisson, O.5    Verge, V.M.6    Persson, H.7
  • 11
    • 0032574739 scopus 로고    scopus 로고
    • Targeted expression of a multifunctional chimeric neurotrophin in the lesioned sciatic nerve accelerates regeneration of sensory and motor axons
    • Funakoshi H, Risling M, Carlstedt T, Lendahl U, Timmusk T, Metsis M, Yamamoto Y, Ibanez CF (1998) Targeted expression of a multifunctional chimeric neurotrophin in the lesioned sciatic nerve accelerates regeneration of sensory and motor axons. Proc Natl Acad Sci USA 95:5269-5274.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5269-5274
    • Funakoshi, H.1    Risling, M.2    Carlstedt, T.3    Lendahl, U.4    Timmusk, T.5    Metsis, M.6    Yamamoto, Y.7    Ibanez, C.F.8
  • 12
    • 0030690490 scopus 로고    scopus 로고
    • The use of transgenic mouse models of amyotrophic lateral sclerosis in preclinical drug studies
    • Gurney ME (1997) The use of transgenic mouse models of amyotrophic lateral sclerosis in preclinical drug studies. J Neurol Sci 152:S67-73.
    • (1997) J Neurol Sci , vol.152
    • Gurney, M.E.1
  • 16
    • 0030612195 scopus 로고    scopus 로고
    • Treatment strategies for neurodegenerative diseases based on trophic factors and cell transplantation techniques
    • Hoffer B, Olson L (1997) Treatment strategies for neurodegenerative diseases based on trophic factors and cell transplantation techniques. J Neural Transm [Suppl] 49:1-10.
    • (1997) J Neural Transm [Suppl] , vol.49 , pp. 1-10
    • Hoffer, B.1    Olson, L.2
  • 17
    • 0029142780 scopus 로고
    • Localization and functional coupling of HGF and c-Met/HGF receptor in rat brain: Implication as neurotrophic factor
    • Honda S, Kagoshima M, Wanaka A, Tohyama M, Matsumoto K, Nakamura T (1995) Localization and functional coupling of HGF and c-Met/HGF receptor in rat brain: Implication as neurotrophic factor. Brain Res Mol Brain Res 32:197-210.
    • (1995) Brain Res Mol Brain Res , vol.32 , pp. 197-210
    • Honda, S.1    Kagoshima, M.2    Wanaka, A.3    Tohyama, M.4    Matsumoto, K.5    Nakamura, T.6
  • 18
    • 0034711151 scopus 로고    scopus 로고
    • Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls
    • Honig LS, Chambliss DD, Bigio EH, Carroll SL, Elliott JL (2000) Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls. Neurology 55:1082-1088.
    • (2000) Neurology , vol.55 , pp. 1082-1088
    • Honig, L.S.1    Chambliss, D.D.2    Bigio, E.H.3    Carroll, S.L.4    Elliott, J.L.5
  • 20
    • 0033067527 scopus 로고    scopus 로고
    • Hepatocyte growth factor prevents endotoxin-induced lethal hepatic failure in mice
    • Kosai K, Matsumoto K, Funakoshi H, Nakamura T (1999) Hepatocyte growth factor prevents endotoxin-induced lethal hepatic failure in mice. Hepatology 30:151-159.
    • (1999) Hepatology , vol.30 , pp. 151-159
    • Kosai, K.1    Matsumoto, K.2    Funakoshi, H.3    Nakamura, T.4
  • 21
    • 0030756459 scopus 로고    scopus 로고
    • Bcl-2: Prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • Kostic V, Jackson-Lewis V, de Bilbao F, Dubois-Dauphin M, Przedborski S (1997) Bcl-2: Prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science 277:559-562.
    • (1997) Science , vol.277 , pp. 559-562
    • Kostic, V.1    Jackson-Lewis, V.2    De Bilbao, F.3    Dubois-Dauphin, M.4    Przedborski, S.5
  • 22
    • 0029977337 scopus 로고    scopus 로고
    • Dose-ranging study of riluzole in amyotrophic lateral sclerosis
    • Amyotrophic lateral sclerosis/riluzole study group II
    • Lacomblez L, Bensimon G, Leigh PN, Guillet P, Meininger V (1996) Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis/riluzole study group II. Lancet 347:1425-1431.
    • (1996) Lancet , vol.347 , pp. 1425-1431
    • Lacomblez, L.1    Bensimon, G.2    Leigh, P.N.3    Guillet, P.4    Meininger, V.5
  • 24
    • 0032032013 scopus 로고    scopus 로고
    • Aberrant RNA processing in a neurodegenerative disease: The cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis
    • Lin CL, Bristol LA, Jin L, Dykes-Hoberg M, Crawford T, Clawson L, Rothstein JD (1998) Aberrant RNA processing in a neurodegenerative disease: The cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis. Neuron 20:589-602.
    • (1998) Neuron , vol.20 , pp. 589-602
    • Lin, C.L.1    Bristol, L.A.2    Jin, L.3    Dykes-Hoberg, M.4    Crawford, T.5    Clawson, L.6    Rothstein, J.D.7
  • 25
    • 0033362351 scopus 로고    scopus 로고
    • Hepatocyte growth factor, a versatile signal for developing neurons
    • Maina F, Klein R (1999) Hepatocyte growth factor, a versatile signal for developing neurons. Nat Neurosci 2:213-217.
    • (1999) Nat Neurosci , vol.2 , pp. 213-217
    • Maina, F.1    Klein, R.2
  • 26
    • 0031299876 scopus 로고    scopus 로고
    • HGF: Its organotrophic role and therapeutic potential
    • Matsumoto K, Nakamura T (1997) HGF: Its organotrophic role and therapeutic potential. Ciba Found Symp 212:198-211.
    • (1997) Ciba Found Symp , vol.212 , pp. 198-211
    • Matsumoto, K.1    Nakamura, T.2
  • 27
    • 0033956281 scopus 로고    scopus 로고
    • Hepatocyte growth factor affects satellite cell activation and differentiation in regenerating skeletal muscle
    • Miller KJ, Thaloor D, Matteson S, Pavlath GK (2000) Hepatocyte growth factor affects satellite cell activation and differentiation in regenerating skeletal muscle. Am J Physiol Cell Physiol 278:C174-181.
    • (2000) Am J Physiol Cell Physiol , vol.278
    • Miller, K.J.1    Thaloor, D.2    Matteson, S.3    Pavlath, G.K.4
  • 29
    • 0021285134 scopus 로고
    • Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
    • Nakamura T, Nawa K, Ichihara A (1984) Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochem Biophys Res Commun 122:1450-1459.
    • (1984) Biochem Biophys Res Commun , vol.122 , pp. 1450-1459
    • Nakamura, T.1    Nawa, K.2    Ichihara, A.3
  • 31
    • 0034526510 scopus 로고    scopus 로고
    • Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF
    • Nakamura T, Mizuno S, Matsumoto K, Sawa Y, Matsuda H, Nakamura T (2000) Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF. J Clin Invest 106:1511-1519.
    • (2000) J Clin Invest , vol.106 , pp. 1511-1519
    • Nakamura, T.1    Mizuno, S.2    Matsumoto, K.3    Sawa, Y.4    Matsuda, H.5    Nakamura, T.6
  • 33
    • 0033999093 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor is a neurotrophic survival factor for lumbar but not for other somatic motoneurons in the chick embryo
    • Novak KD, Prevette D, Wang S, Gould TW, Oppenheim RW (2000) Hepatocyte growth factor/scatter factor is a neurotrophic survival factor for lumbar but not for other somatic motoneurons in the chick embryo. J Neurosci 20:326-337.
    • (2000) J Neurosci , vol.20 , pp. 326-337
    • Novak, K.D.1    Prevette, D.2    Wang, S.3    Gould, T.W.4    Oppenheim, R.W.5
  • 35
    • 0032430185 scopus 로고    scopus 로고
    • Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase
    • Pasinelli P, Borchelt DR, Houseweart MK, Cleveland DW, Brown Jr RH (1998) Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase. Proc Natl Acad Sci USA 95:15763-15768.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15763-15768
    • Pasinelli, P.1    Borchelt, D.R.2    Houseweart, M.K.3    Cleveland, D.W.4    Brown R.H., Jr.5
  • 36
    • 0034326760 scopus 로고    scopus 로고
    • German open label trial of riluzole 50 mg b.i.d. in treatment of amyotrophic lateral sclerosis (ALS)
    • Pongratz D, Neundorfer B, Fischer W (2000) German open label trial of riluzole 50 mg b.i.d. in treatment of amyotrophic lateral sclerosis (ALS). J Neurol Sci 180:82-85.
    • (2000) J Neurol Sci , vol.180 , pp. 82-85
    • Pongratz, D.1    Neundorfer, B.2    Fischer, W.3
  • 38
    • 0026597010 scopus 로고
    • Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
    • Rothstein JD, Martin LJ, Kuncl RW (1992) Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N Engl J Med 326:1464-1468.
    • (1992) N Engl J Med , vol.326 , pp. 1464-1468
    • Rothstein, J.D.1    Martin, L.J.2    Kuncl, R.W.3
  • 39
    • 0029030610 scopus 로고
    • Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
    • Rothstein JD, Van Kammen M, Levey AI, Martin LJ, Kuncl RW (1995) Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann Neurol 38:73-84.
    • (1995) Ann Neurol , vol.38 , pp. 73-84
    • Rothstein, J.D.1    Van Kammen, M.2    Levey, A.I.3    Martin, L.J.4    Kuncl, R.W.5
  • 40
    • 0029950147 scopus 로고    scopus 로고
    • GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice
    • Sagot Y, Tan SA, Hammang JP, Aebischer P, Kato AC (1996) GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice. J Neurosci 16:2335-2341.
    • (1996) J Neurosci , vol.16 , pp. 2335-2341
    • Sagot, Y.1    Tan, S.A.2    Hammang, J.P.3    Aebischer, P.4    Kato, A.C.5
  • 42
    • 0032744516 scopus 로고    scopus 로고
    • Neurofilament metabolism in sporadic amyotrophic lateral sclerosis
    • Strong MJ (1999) Neurofilament metabolism in sporadic amyotrophic lateral sclerosis. J Neurol Sci 169:170-177.
    • (1999) J Neurol Sci , vol.169 , pp. 170-177
    • Strong, M.J.1
  • 43
    • 0033397021 scopus 로고    scopus 로고
    • Differential expression of hepatocyte growth factor and its receptor, c-Met, in the rat retina during development
    • Sun W, Funakoshi H, Nakamura T (1999) Differential expression of hepatocyte growth factor and its receptor, c-Met, in the rat retina during development. Brain Res 851:46-53.
    • (1999) Brain Res , vol.851 , pp. 46-53
    • Sun, W.1    Funakoshi, H.2    Nakamura, T.3
  • 44
    • 0034077611 scopus 로고    scopus 로고
    • A sensitive quantification method for evaluating the level of hepatocyte growth factor and c-met/HGF receptor mRNAs in the nervous system using competitive RT-PCR
    • Sun W, Funakoshi H, Matsumoto K, Nakamura T (2000) A sensitive quantification method for evaluating the level of hepatocyte growth factor and c-met/HGF receptor mRNAs in the nervous system using competitive RT-PCR. Brain Res Brain Res Protoc 5:190-197.
    • (2000) Brain Res Brain Res Protoc , vol.5 , pp. 190-197
    • Sun, W.1    Funakoshi, H.2    Matsumoto, K.3    Nakamura, T.4
  • 46
    • 0035283075 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: A mechanism distinct from chronic neurotoxicity after Ca(2+) influx
    • Urushitani M, Nakamizo T, Inoue R, Sawada H, Kihara T, Honda K, Akaike A, Shimohama S (2001) N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: A mechanism distinct from chronic neurotoxicity after Ca(2+) influx. J Neurosci Res 63:377-387.
    • (2001) J Neurosci Res , vol.63 , pp. 377-387
    • Urushitani, M.1    Nakamizo, T.2    Inoue, R.3    Sawada, H.4    Kihara, T.5    Honda, K.6    Akaike, A.7    Shimohama, S.8
  • 47
    • 0032750753 scopus 로고    scopus 로고
    • Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • Vukosavic S, Dubois-Dauphin M, Romero N, Przedborski S (1999) Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis. J Neurochem 73:2460-2468.
    • (1999) J Neurochem , vol.73 , pp. 2460-2468
    • Vukosavic, S.1    Dubois-Dauphin, M.2    Romero, N.3    Przedborski, S.4
  • 48
    • 0030865088 scopus 로고    scopus 로고
    • Hepatocyte growth factor (HGF/SF) is a muscle-derived survival factor for a subpopulation of embryonic motoneurons
    • Yamamoto Y, Livet J, Pollock RA, Garces A, Arce V, deLapeyriere O, Henderson CE (1997) Hepatocyte growth factor (HGF/SF) is a muscle-derived survival factor for a subpopulation of embryonic motoneurons. Development 124:2903-2913.
    • (1997) Development , vol.124 , pp. 2903-2913
    • Yamamoto, Y.1    Livet, J.2    Pollock, R.A.3    Garces, A.4    Arce, V.5    DeLapeyriere, O.6    Henderson, C.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.