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Volumn 15, Issue 4, 2002, Pages 613-626

A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor

Author keywords

BDNF; Motoneuron; p75; Retrograde tracers; Sprague Dawley; trkB

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; PROTEIN P75; RECEPTOR; TRACER;

EID: 0036460111     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2002.01891.x     Document Type: Article
Times cited : (239)

References (65)
  • 1
    • 84914639435 scopus 로고
    • Estimation of nuclear population from microtome sections
    • Abercrombie, M. (1946) Estimation of nuclear population from microtome sections. Anat. Rec., 94, 239-247.
    • (1946) Anat. Rec. , vol.94 , pp. 239-247
    • Abercrombie, M.1
  • 2
    • 0030995057 scopus 로고    scopus 로고
    • TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death
    • Alcantara, S., Frisen, J., del Rio, J.A., Soriano, E., Barbacid, M. & Silos-Santiago, I. (1997) TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death. J. Neurosci., 17, 3623-3633.
    • (1997) J. Neurosci. , vol.17 , pp. 3623-3633
    • Alcantara, S.1    Frisen, J.2    Del Rio, J.A.3    Soriano, E.4    Barbacid, M.5    Silos-Santiago, I.6
  • 3
    • 0034509612 scopus 로고    scopus 로고
    • Electrical stimulation accelerates and increases expression of BDNF and trkB mRNA in regenerating rat femoral motoneurons
    • Al-Majed, A.A., Brushart, T.M. & Gordon, T. (2000b) Electrical stimulation accelerates and increases expression of BDNF and trkB mRNA in regenerating rat femoral motoneurons. Eur. J. Neurosci., 12, 4381-4390.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 4381-4390
    • Al-Majed, A.A.1    Brushart, T.M.2    Gordon, T.3
  • 4
    • 0034175684 scopus 로고    scopus 로고
    • Brief electrical stimulation promotes the speed and accuracy of motor axonal regeneration
    • Al-Majed, A.A., Neumann, C.M., Brushart, T.M. & Gordon, T. (2000a) Brief electrical stimulation promotes the speed and accuracy of motor axonal regeneration. J. Neurosci., 20, 2602-2608.
    • (2000) J. Neurosci. , vol.20 , pp. 2602-2608
    • Al-Majed, A.A.1    Neumann, C.M.2    Brushart, T.M.3    Gordon, T.4
  • 5
    • 0033694754 scopus 로고    scopus 로고
    • The trkB-shc site signals neuronal survival and local axon growth via MEK and PI3-kinase
    • Atwal, J.K., Massie, B., Miller, F.D. & Kaplan, D.R. (2000) The trkB-shc site signals neuronal survival and local axon growth via MEK and PI3-kinase. Neuron, 27, 265-277.
    • (2000) Neuron , vol.27 , pp. 265-277
    • Atwal, J.K.1    Massie, B.2    Miller, F.D.3    Kaplan, D.R.4
  • 6
    • 0028931552 scopus 로고
    • Neurotrophic factors and their receptors
    • Barbacid, M. (1994) Neurotrophic factors and their receptors. Curr. Opin. Cell Biol., 7, 148-155.
    • (1994) Curr. Opin. Cell Biol. , vol.7 , pp. 148-155
    • Barbacid, M.1
  • 7
    • 0035196610 scopus 로고    scopus 로고
    • The neurotrophin receptors, trkB and p75, differentially regulate motor axonal regeneration
    • Boyd, J.G. & Gordon, T. (2001) The neurotrophin receptors, trkB and p75, differentially regulate motor axonal regeneration. J. Neurobiol., 49, 314-325.
    • (2001) J. Neurobiol. , vol.49 , pp. 314-325
    • Boyd, J.G.1    Gordon, T.2
  • 8
    • 0024352081 scopus 로고
    • Role of peripheral nerve extracellular matrix in Schwann cell function and in neurite regeneration
    • Bunge, M.B., Bunge, R.P., Kleitman, N. & Dean, A.C. (1989) Role of peripheral nerve extracellular matrix in Schwann cell function and in neurite regeneration. Dev. Neurosci., 11, 348-360.
    • (1989) Dev. Neurosci. , vol.11 , pp. 348-360
    • Bunge, M.B.1    Bunge, R.P.2    Kleitman, N.3    Dean, A.C.4
  • 11
    • 0031880055 scopus 로고    scopus 로고
    • Coupling of the p75 neurotrophin receptor to sphingolipid signaling
    • Dobrowsky, R.T. & Carter, B.D. (1998) Coupling of the p75 neurotrophin receptor to sphingolipid signaling. Ann. NY Acad. Sci., 845, 32-45.
    • (1998) Ann. NY Acad. Sci. , vol.845 , pp. 32-45
    • Dobrowsky, R.T.1    Carter, B.D.2
  • 12
    • 0032806529 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediated brain-derived neurotrophic factor-induced motoneuron survival
    • Dolcet, X., Egea, J., Soler, R.M., Martin-Zanca, D. & Comella, J.X. (1999) Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediated brain-derived neurotrophic factor-induced motoneuron survival. J. Neurochem., 73, 521-531.
    • (1999) J. Neurochem. , vol.73 , pp. 521-531
    • Dolcet, X.1    Egea, J.2    Soler, R.M.3    Martin-Zanca, D.4    Comella, J.X.5
  • 13
    • 0024679252 scopus 로고
    • Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons
    • Ernfors, P., Henschen, A., Olson, L. & Persson, H. (1989) Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons. Neuron, 2, 1603-1613.
    • (1989) Neuron , vol.2 , pp. 1603-1613
    • Ernfors, P.1    Henschen, A.2    Olson, L.3    Persson, H.4
  • 14
    • 0032831279 scopus 로고    scopus 로고
    • Improved survival of injured sciatic nerve Schwann cells in mice lacking the p75 receptor
    • Ferri, C.C. & Bisby, M.A. (1999) Improved survival of injured sciatic nerve Schwann cells in mice lacking the p75 receptor. Neurosci. Lett., 272, 191-194.
    • (1999) Neurosci. Lett. , vol.272 , pp. 191-194
    • Ferri, C.C.1    Bisby, M.A.2
  • 15
    • 0031982883 scopus 로고    scopus 로고
    • Effects of facial nerve injury on mouse motoneurons lacking the p75 low-affinity neurotrophin receptor
    • Ferri, C.C., Moore, F.A. & Bisby, M.A. (1998) Effects of facial nerve injury on mouse motoneurons lacking the p75 low-affinity neurotrophin receptor. J. Neurobiol., 34, 1-9.
    • (1998) J. Neurobiol. , vol.34 , pp. 1-9
    • Ferri, C.C.1    Moore, F.A.2    Bisby, M.A.3
  • 16
    • 0029946148 scopus 로고    scopus 로고
    • BDNF downregulates neurotrophin responsiveness. TrkB protein and TrkB mRNA levels in cultured rat hippocampal neurons
    • Frank, L., Ventimiglia, R., Anderson, K., Lindsay, R.M. & Rudge, J.S. (1996) BDNF downregulates neurotrophin responsiveness, TrkB protein and TrkB mRNA levels in cultured rat hippocampal neurons. Eur. J. Neurosci., 8, 1220-1230.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1220-1230
    • Frank, L.1    Ventimiglia, R.2    Anderson, K.3    Lindsay, R.M.4    Rudge, J.S.5
  • 17
    • 0031149621 scopus 로고    scopus 로고
    • Effects of BDNF infusion on the regulation of TrkB protein and message in adult rat brain
    • Frank, L., Wiegand, S.J., Siuciak, J.A., Lindsay, R.M. & Rudge, J.S. (1997) Effects of BDNF infusion on the regulation of TrkB protein and message in adult rat brain. Exp. Neurol., 145, 62-70.
    • (1997) Exp. Neurol. , vol.145 , pp. 62-70
    • Frank, L.1    Wiegand, S.J.2    Siuciak, J.A.3    Lindsay, R.M.4    Rudge, J.S.5
  • 19
    • 0029032791 scopus 로고
    • Contributing factors to poor functional recovery after delayed nerve repair: Prolonged axotomy
    • Fu, S.Y. & Gordon, T. (1995) Contributing factors to poor functional recovery after delayed nerve repair: Prolonged axotomy. J. Neurosci., 15, 3876-3885.
    • (1995) J. Neurosci. , vol.15 , pp. 3876-3885
    • Fu, S.Y.1    Gordon, T.2
  • 20
    • 0031063473 scopus 로고    scopus 로고
    • The cellular and molecular basis of peripheral nerve regeneration
    • Fu, S.Y. & Gordon, T. (1997) The cellular and molecular basis of peripheral nerve regeneration. Mol. Neurobiol., 14, 67-116.
    • (1997) Mol. Neurobiol. , vol.14 , pp. 67-116
    • Fu, S.Y.1    Gordon, T.2
  • 21
    • 0027360908 scopus 로고
    • Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve
    • Funakoshi, H., Frisen, J., Barbany, G., Timmusk, T., Zacrisson, O., Verge, V.M.K. & Persson, H. (1993) Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve. J. Cell Biol., 123, 455-465.
    • (1993) J. Cell Biol. , vol.123 , pp. 455-465
    • Funakoshi, H.1    Frisen, J.2    Barbany, G.3    Timmusk, T.4    Zacrisson, O.5    Verge, V.M.K.6    Persson, H.7
  • 22
    • 0025948750 scopus 로고
    • Axotomy-induced changes in rabbit hindlimb nerves and the effects of chronic electrical stimulation
    • Gordon, T., Gillespie, J., Orozco, R. & Davis, L. (1991) Axotomy-induced changes in rabbit hindlimb nerves and the effects of chronic electrical stimulation. J. Neurosci., 11, 2157-2169.
    • (1991) J. Neurosci. , vol.11 , pp. 2157-2169
    • Gordon, T.1    Gillespie, J.2    Orozco, R.3    Davis, L.4
  • 23
    • 0030296417 scopus 로고    scopus 로고
    • Motoneuronal survival: A functional approach
    • Greensmith, L. & Vrbova, G. (1996) Motoneuronal survival: A functional approach. Trends Neurosci., 19, 450-455.
    • (1996) Trends Neurosci. , vol.19 , pp. 450-455
    • Greensmith, L.1    Vrbova, G.2
  • 24
    • 0033771487 scopus 로고    scopus 로고
    • Differential regulation of trophic factor receptor mRNAs in spinal motoneurons after sciatic nerve transection and ventral root avulsion in the rat
    • Hammarberg, H., Piehl, F., Risling, M. & Cullheim, S. (2000) Differential regulation of trophic factor receptor mRNAs in spinal motoneurons after sciatic nerve transection and ventral root avulsion in the rat. J. Comp. Neurol., 426, 587-601.
    • (2000) J. Comp. Neurol. , vol.426 , pp. 587-601
    • Hammarberg, H.1    Piehl, F.2    Risling, M.3    Cullheim, S.4
  • 25
    • 0031869497 scopus 로고    scopus 로고
    • Repair with collagen tubules linked with brain-derived neurotrophic factor and ciliary neurotrophic factor in a rat sciatic nerve injury model
    • Ho, R., Coan, G.M., Cheng, E.T., Niell, C., Tarn, D.M., Zhou, H., Sierra, D. & Terris, D.J. (1998) Repair with collagen tubules linked with brain-derived neurotrophic factor and ciliary neurotrophic factor in a rat sciatic nerve injury model. Arch. Otolaryngol. Head Neck Surg., 124, 761-766.
    • (1998) Arch. Otolaryngol. Head Neck Surg. , vol.124 , pp. 761-766
    • Ho, R.1    Coan, G.M.2    Cheng, E.T.3    Niell, C.4    Tarn, D.M.5    Zhou, H.6    Sierra, D.7    Terris, D.J.8
  • 26
    • 0024535958 scopus 로고
    • A laminin-like adhesive protein concentrated at the synaptic cleft of the neuromuscular junction
    • Hunter, D.D., Shah, V., Merlie, J.P. & Sanes, J.R. (1989) A laminin-like adhesive protein concentrated at the synaptic cleft of the neuromuscular junction. Nature, 338, 229-334.
    • (1989) Nature , vol.338 , pp. 229-334
    • Hunter, D.D.1    Shah, V.2    Merlie, J.P.3    Sanes, J.R.4
  • 27
    • 0031128211 scopus 로고    scopus 로고
    • BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth
    • Kishino, A., Ishige, Y., Tatsuno, T., Nakayama, C. & Noguchi, H. (1997) BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth. Exp. Neurol., 144, 273-286.
    • (1997) Exp. Neurol. , vol.144 , pp. 273-286
    • Kishino, A.1    Ishige, Y.2    Tatsuno, T.3    Nakayama, C.4    Noguchi, H.5
  • 28
    • 0031940544 scopus 로고    scopus 로고
    • Free radical scavenging and inhibition of nitric oxide synthase potentiates the neurotrophic effects of brain-derived neurotrophic factor on axotomized retinal ganglion cells in vivo
    • Klöcker, N., Cellerino, A. & Bähr, M. (1998) Free radical scavenging and inhibition of nitric oxide synthase potentiates the neurotrophic effects of brain-derived neurotrophic factor on axotomized retinal ganglion cells in vivo. J. Neurosci., 18, 1038-1046.
    • (1998) J. Neurosci. , vol.18 , pp. 1038-1046
    • Klöcker, N.1    Cellerino, A.2    Bähr, M.3
  • 29
    • 0029929873 scopus 로고    scopus 로고
    • Intraparenchymal NGF injections in adult and aged rats induce longlasting Trk tyrosine phosphorylation
    • Knusel, B., Kaplan, D.R. & Hefti, F. (1996) Intraparenchymal NGF injections in adult and aged rats induce longlasting Trk tyrosine phosphorylation. Exp. Neurol., 139, 121-130.
    • (1996) Exp. Neurol. , vol.139 , pp. 121-130
    • Knusel, B.1    Kaplan, D.R.2    Hefti, F.3
  • 30
    • 0030005125 scopus 로고    scopus 로고
    • Increased expression of BDNF and trkB mRNA in rat facial motoneurons after axotomy
    • Kobayashi, N.R., Bedard, A.N., Hincke, M.T. & Tetzlaff, W. (1996) Increased expression of BDNF and trkB mRNA in rat facial motoneurons after axotomy. Eur. J. Neurosci., 8, 1018-1029.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1018-1029
    • Kobayashi, N.R.1    Bedard, A.N.2    Hincke, M.T.3    Tetzlaff, W.4
  • 31
    • 0031467240 scopus 로고    scopus 로고
    • BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Tα1-tubulin mRNA expression, and promote axonal regeneration
    • Kobayashi, N.R., Fan, D.-P., Giehl, K.M., Bedard, A.M., Wiegand, S.J. & Tetzlaff, W. (1997) BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Tα1-tubulin mRNA expression, and promote axonal regeneration. J. Neurosci., 17, 9583-9595.
    • (1997) J. Neurosci. , vol.17 , pp. 9583-9595
    • Kobayashi, N.R.1    Fan, D.-P.2    Giehl, K.M.3    Bedard, A.M.4    Wiegand, S.J.5    Tetzlaff, W.6
  • 32
    • 0033168353 scopus 로고    scopus 로고
    • Functionally antagonistic interactions between the trkA and p75 neurotrophin receptors regulate sympathetic neuron growth and target innervation
    • Kohn, J., Aloyz, R.S., Toma, J.G., Haak-Frendscho, M. & Miller, F.D. (1999) Functionally antagonistic interactions between the trkA and p75 neurotrophin receptors regulate sympathetic neuron growth and target innervation. J. Neurosci., 19, 5393-5408.
    • (1999) J. Neurosci. , vol.19 , pp. 5393-5408
    • Kohn, J.1    Aloyz, R.S.2    Toma, J.G.3    Haak-Frendscho, M.4    Miller, F.D.5
  • 33
    • 0027481752 scopus 로고
    • Evidence that brain derived neurotrophic factor is a tropic factor for motor neurons in vivo
    • Koliatsos, V.E., Cayouette, M.H., Berkemeier, L.R., Clatterbuck, R.E. & Price, D.L. (1993) Evidence that brain derived neurotrophic factor is a tropic factor for motor neurons in vivo. Neuron, 10, 359-367.
    • (1993) Neuron , vol.10 , pp. 359-367
    • Koliatsos, V.E.1    Cayouette, M.H.2    Berkemeier, L.R.3    Clatterbuck, R.E.4    Price, D.L.5
  • 34
    • 0030741376 scopus 로고    scopus 로고
    • Simultaneous treatment with BDNF and CNTF after peripheral nerve transection and repair enhances rate of functional recovery compared with BDNF treatment alone
    • Lewin, S.L., Utley, D.S., Cheng, E.T., Verity, A.N. & Terris, D.J. (1997) Simultaneous treatment with BDNF and CNTF after peripheral nerve transection and repair enhances rate of functional recovery compared with BDNF treatment alone. Laryngoscope, 107, 992-999.
    • (1997) Laryngoscope , vol.107 , pp. 992-999
    • Lewin, S.L.1    Utley, D.S.2    Cheng, E.T.3    Verity, A.N.4    Terris, D.J.5
  • 35
    • 0026768108 scopus 로고
    • Enhanced synthesis of brain derived neurotrophic factor in the lesioned peripheral nerve: Different mechanisms are responsible for the regulation of BDNF and NGF mRNA
    • Meyer, M., Tatsuoka, I., Wetmore, C., Olson, L. & Thoenen, H. (1992) Enhanced synthesis of brain derived neurotrophic factor in the lesioned peripheral nerve: Different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J. Cell Biol., 119, 45-54.
    • (1992) J. Cell Biol. , vol.119 , pp. 45-54
    • Meyer, M.1    Tatsuoka, I.2    Wetmore, C.3    Olson, L.4    Thoenen, H.5
  • 36
    • 0034113445 scopus 로고    scopus 로고
    • Delayed repair of transected nerves: Effect of brain-derived neurotrophic factor
    • Moir, M.S., Wang, M.Z., To, M., Lum, J. & Terris, D.J. (2000) Delayed repair of transected nerves: Effect of brain-derived neurotrophic factor. Arch. Otolaryngol. Head Neck Surg., 126, 501-505.
    • (2000) Arch. Otolaryngol. Head Neck Surg. , vol.126 , pp. 501-505
    • Moir, M.S.1    Wang, M.Z.2    To, M.3    Lum, J.4    Terris, D.J.5
  • 37
    • 0031027332 scopus 로고    scopus 로고
    • Adult mammalian sensory and motor neurons: Roles of endogenous neurotrophins and rescue by exogenous neurotrophins after axotomy
    • Munson, J.B., Shelton, D.L. & McMahon, S.B. (1997) Adult mammalian sensory and motor neurons: Roles of endogenous neurotrophins and rescue by exogenous neurotrophins after axotomy. J. Neurosci., 17, 470-476.
    • (1997) J. Neurosci. , vol.17 , pp. 470-476
    • Munson, J.B.1    Shelton, D.L.2    McMahon, S.B.3
  • 38
    • 0034655803 scopus 로고    scopus 로고
    • Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration
    • Namikawa, K., Honma, M., Abe, K., Takeda, M., Mansur, K., Obata, T., Miwa, A., Okado, H. & Kiyama, H. (2000) Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration. J. Neurosci., 20, 2875-2886.
    • (2000) J. Neurosci. , vol.20 , pp. 2875-2886
    • Namikawa, K.1    Honma, M.2    Abe, K.3    Takeda, M.4    Mansur, K.5    Obata, T.6    Miwa, A.7    Okado, H.8    Kiyama, H.9
  • 39
    • 0028908326 scopus 로고
    • Aberrant differentiation of neuromuscular junctions in mice lacking S-laminin/laminin beta 2
    • Noakes, P.G., Gautam, M., Mudd, J., Sanes, J.R. & Merlie, J.P. (1995) Aberrant differentiation of neuromuscular junctions in mice lacking S-laminin/laminin beta 2. Nature, 374, 258-262.
    • (1995) Nature , vol.374 , pp. 258-262
    • Noakes, P.G.1    Gautam, M.2    Mudd, J.3    Sanes, J.R.4    Merlie, J.P.5
  • 40
    • 0030762723 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo
    • Novikov, L., Novikova, L. & Kellerth, J.-O. (1997) Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo. Neuroscience, 79, 765-774.
    • (1997) Neuroscience , vol.79 , pp. 765-774
    • Novikov, L.1    Novikova, L.2    Kellerth, J.-O.3
  • 41
    • 0006976007 scopus 로고    scopus 로고
    • Cytoskeletal protein expression in long-term axotomized facial and sciatic motoneurons
    • Petrov, T., You, S., Cassar, S.L., Tetzlaff, W. & Gordon, T. (1996) Cytoskeletal protein expression in long-term axotomized facial and sciatic motoneurons. Soc. Neurosci. Abstr., 22, 231. 19.
    • (1996) Soc. Neurosci. Abstr. , vol.22 , pp. 23119
    • Petrov, T.1    You, S.2    Cassar, S.L.3    Tetzlaff, W.4    Gordon, T.5
  • 42
    • 0031938716 scopus 로고    scopus 로고
    • Differential effects of neurotrophic factors on motoneuron retrograde labeling in a murine model of motoneuron disease
    • Sagot, Y., Rosse, T., Vejsada, R., Perrelet, D. & Kato, A.C. (1998) Differential effects of neurotrophic factors on motoneuron retrograde labeling in a murine model of motoneuron disease. J. Neurosci., 18, 1132-1141.
    • (1998) J. Neurosci. , vol.18 , pp. 1132-1141
    • Sagot, Y.1    Rosse, T.2    Vejsada, R.3    Perrelet, D.4    Kato, A.C.5
  • 43
    • 0022503229 scopus 로고
    • Fluoro-Gold: A new fluorescent retrograde axonal tracer with numerous unique properties
    • Schmued, L.C. & Fallon, J.H. (1986) Fluoro-Gold: A new fluorescent retrograde axonal tracer with numerous unique properties. Brain Res., 377, 147-154.
    • (1986) Brain Res. , vol.377 , pp. 147-154
    • Schmued, L.C.1    Fallon, J.H.2
  • 44
    • 0027070473 scopus 로고
    • Brain derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
    • Sendtner, M., Holtmann, B., Kolbeck, R., Thoenen, H. & Barde, Y.-A. (1992) Brain derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature, 360, 757-758.
    • (1992) Nature , vol.360 , pp. 757-758
    • Sendtner, M.1    Holtmann, B.2    Kolbeck, R.3    Thoenen, H.4    Barde, Y.-A.5
  • 45
    • 0029993611 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and peripheral nerve regeneration: A functional evaluation
    • Shirley, D.M., Williams, S.A. & Santos, P.M. (1996) Brain-derived neurotrophic factor and peripheral nerve regeneration: A functional evaluation. Laryngoscope, 106, 629-632.
    • (1996) Laryngoscope , vol.106 , pp. 629-632
    • Shirley, D.M.1    Williams, S.A.2    Santos, P.M.3
  • 46
    • 0034026922 scopus 로고    scopus 로고
    • Differential effects of NT-3 on reinnervation of the fast extensor digitorum longus (EDL) and the slow soleus muscle of rat
    • Simon, M., Terenghi, G., Green, C.J. & Coulton, G.R. (2000) Differential effects of NT-3 on reinnervation of the fast extensor digitorum longus (EDL) and the slow soleus muscle of rat. Eur. J. Neurosci., 12, 863-871.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 863-871
    • Simon, M.1    Terenghi, G.2    Green, C.J.3    Coulton, G.R.4
  • 47
    • 0030844868 scopus 로고    scopus 로고
    • Neurotrophin-3 delivered locally via fibronectin mats enhances peripheral nerve regeneration
    • Sterne, G.D., Brown, R.A., Green, C.J. & Terenghi, G. (1997a) Neurotrophin-3 delivered locally via fibronectin mats enhances peripheral nerve regeneration. Eur. J. Neurosci., 9, 1388-1396.
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 1388-1396
    • Sterne, G.D.1    Brown, R.A.2    Green, C.J.3    Terenghi, G.4
  • 48
    • 0030722571 scopus 로고    scopus 로고
    • Neurotrophin-3-enhanced nerve regeneration selectively improves recovery of muscle fibres expression myosin heavy chains 2b
    • Sterne, G.D., Coulton, G.R., Brown, R.A., Green, C.J. & Terenghi, G. (1997b) Neurotrophin-3-enhanced nerve regeneration selectively improves recovery of muscle fibres expression myosin heavy chains 2b. J. Cell Biol., 139, 709-715.
    • (1997) J. Cell Biol. , vol.139 , pp. 709-715
    • Sterne, G.D.1    Coulton, G.R.2    Brown, R.A.3    Green, C.J.4    Terenghi, G.5
  • 50
    • 0033021524 scopus 로고    scopus 로고
    • Peripheral nerve regeneration and neurotrophic factors
    • Terenghi, G. (1999) Peripheral nerve regeneration and neurotrophic factors. J. Anat., 194, 1-14.
    • (1999) J. Anat. , vol.194 , pp. 1-14
    • Terenghi, G.1
  • 51
    • 0026014670 scopus 로고
    • Response of facial and rubrospinal neurons to axotomy: Changes in mRNA expression for cytoskeletal proteins and GAP-43
    • Tetzlaff, W., Alexander, S.W., Miller, F.D. & Bisby, M.A. (1991) Response of facial and rubrospinal neurons to axotomy: Changes in mRNA expression for cytoskeletal proteins and GAP-43. J. Neurosci., 11, 2528-2544.
    • (1991) J. Neurosci. , vol.11 , pp. 2528-2544
    • Tetzlaff, W.1    Alexander, S.W.2    Miller, F.D.3    Bisby, M.A.4
  • 52
    • 0028866230 scopus 로고
    • Neurotrophins and neuronal plasticity
    • Thoenen, H. (1995) Neurotrophins and neuronal plasticity. Science, 270, 593-598.
    • (1995) Science , vol.270 , pp. 593-598
    • Thoenen, H.1
  • 53
    • 0030051807 scopus 로고    scopus 로고
    • Central infusions of brainderived neurotrophic factor and neurotrophin4/5, but not nerve growth factor and neurotrophin3, prevent loss of the cholinergic phenotype in injured adult motor neurons
    • Tuszynski, M.H., Mafong, E. & Meyer, S. (1996) Central infusions of brainderived neurotrophic factor and neurotrophin4/5, but not nerve growth factor and neurotrophin3, prevent loss of the cholinergic phenotype in injured adult motor neurons. Neuroscience, 71, 761-771.
    • (1996) Neuroscience , vol.71 , pp. 761-771
    • Tuszynski, M.H.1    Mafong, E.2    Meyer, S.3
  • 54
    • 0029960960 scopus 로고    scopus 로고
    • Brain derived neurotrophic factor and collagen tubulization enhance functional recovery after peripheral nerve transection and repair
    • Utley, D.S., Lewin, S.L., Cheng, E.T., Verity, N., Sierra, D. & Terris, D.J. (1996) Brain derived neurotrophic factor and collagen tubulization enhance functional recovery after peripheral nerve transection and repair. Arch. Otolaryngol. Head Neck Surg., 122, 407-413.
    • (1996) Arch. Otolaryngol. Head Neck Surg. , vol.122 , pp. 407-413
    • Utley, D.S.1    Lewin, S.L.2    Cheng, E.T.3    Verity, N.4    Sierra, D.5    Terris, D.J.6
  • 55
    • 0027424259 scopus 로고
    • Adult spinal motoneurons remain viable despite prolonged absence of functional synaptic contact with muscle
    • Vanden Noven, S., Wallace, N., Muccio, D., Turtz, A. & Pinter, M.J. (1993) Adult spinal motoneurons remain viable despite prolonged absence of functional synaptic contact with muscle. Exp. Neurol., 123, 147-156.
    • (1993) Exp. Neurol. , vol.123 , pp. 147-156
    • Vanden Noven, S.1    Wallace, N.2    Muccio, D.3    Turtz, A.4    Pinter, M.J.5
  • 56
    • 0027936521 scopus 로고
    • BDNF-mediated rescue of axotomized motor neurons decreases with increasing dose
    • Vejsada, R., Sagot, Y. & Kato, A.C. (1994) BDNF-mediated rescue of axotomized motor neurons decreases with increasing dose. Neuroreport, 5, 1889-1892.
    • (1994) Neuroreport , vol.5 , pp. 1889-1892
    • Vejsada, R.1    Sagot, Y.2    Kato, A.C.3
  • 57
    • 0031938822 scopus 로고    scopus 로고
    • Synergistic but transient rescue effects of BDNF and GDNF on axotomized neonatal motoneurons
    • Vejsada, R., Tseng, J.L., Lindsay, R.M., Acheson, A., Aebischer, P. & Kato, A.C. (1998) Synergistic but transient rescue effects of BDNF and GDNF on axotomized neonatal motoneurons. Neuroscience, 84, 129-139.
    • (1998) Neuroscience , vol.84 , pp. 129-139
    • Vejsada, R.1    Tseng, J.L.2    Lindsay, R.M.3    Acheson, A.4    Aebischer, P.5    Kato, A.C.6
  • 58
    • 0032911947 scopus 로고    scopus 로고
    • Absence of the p75 neurotrophin receptor alters the pattern of sympathosensory sprouting in the trigeminal ganglia of mice overexpressing nerve growth factor
    • Walsh, G.S., Krol, K.M. & Kawaja, M.D. (1999) Absence of the p75 neurotrophin receptor alters the pattern of sympathosensory sprouting in the trigeminal ganglia of mice overexpressing nerve growth factor. J. Neurosci., 19, 258-273.
    • (1999) J. Neurosci. , vol.19 , pp. 258-273
    • Walsh, G.S.1    Krol, K.M.2    Kawaja, M.D.3
  • 59
    • 0025752828 scopus 로고
    • Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors
    • Weskamp, G. & Reichardt, L.F. (1991) Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors. Neuron, 6, 649-663.
    • (1991) Neuron , vol.6 , pp. 649-663
    • Weskamp, G.1    Reichardt, L.F.2
  • 60
    • 0032589258 scopus 로고    scopus 로고
    • The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons
    • Wiese, S., Metzger, F., Holtmann, B. & Sendtner, M. (1999) The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons. Eur. J. Neurosci., 11, 1668-1676.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 1668-1676
    • Wiese, S.1    Metzger, F.2    Holtmann, B.3    Sendtner, M.4
  • 61
    • 0033230625 scopus 로고    scopus 로고
    • Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth
    • Yamashita, T., Tucker, K.L. & Barde, Y.A. (1999) Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth. Neuron, 24, 585-593.
    • (1999) Neuron , vol.24 , pp. 585-593
    • Yamashita, T.1    Tucker, K.L.2    Barde, Y.A.3
  • 62
    • 0027067035 scopus 로고
    • Brain derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death
    • Yan, Q., Elliott, J. & Snider, W.D. (1992) Brain derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature, 360, 753-755.
    • (1992) Nature , vol.360 , pp. 753-755
    • Yan, Q.1    Elliott, J.2    Snider, W.D.3
  • 63
    • 0027969192 scopus 로고
    • The biological responses of axotomized adult motoneurons to brain-derived neurotrophic factor
    • Yan, Q., Matheson, C., Lopez, O.T. & Miller, J.A. (1994) The biological responses of axotomized adult motoneurons to brain-derived neurotrophic factor. J. Neurosci., 14, 5281-5291.
    • (1994) J. Neurosci. , vol.14 , pp. 5281-5291
    • Yan, Q.1    Matheson, C.2    Lopez, O.T.3    Miller, J.A.4
  • 64
    • 0031172095 scopus 로고    scopus 로고
    • The expression of low affinity nerve growth factor receptor in long-term denervated Schwann cells
    • You, S., Petrov, T., Chung, P.H. & Gordon, T. (1996) The expression of low affinity nerve growth factor receptor in long-term denervated Schwann cells. Glia, 20, 87-100.
    • (1996) Glia , vol.20 , pp. 87-100
    • You, S.1    Petrov, T.2    Chung, P.H.3    Gordon, T.4
  • 65
    • 0034507954 scopus 로고    scopus 로고
    • Endogenous BDNF is required for myelination and regeneration of injured sciatic nerve in rodents
    • Zhang, J.Y., Luo, X.G., Xian, C.J., Liu, Z.H. & Zhou, X.F. (2000) Endogenous BDNF is required for myelination and regeneration of injured sciatic nerve in rodents. Eur. J. Neurosci., 12, 4171-4180.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 4171-4180
    • Zhang, J.Y.1    Luo, X.G.2    Xian, C.J.3    Liu, Z.H.4    Zhou, X.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.