Cervical root repair in adult rats after transection: Recovery of forelimb motor function

Experimental Neurology

Volumn 180, Issue 2, 2003, Pages 101-109

  Huang, Ming Chao ^a,b,c   Chen, Kuo Chi ^b   Chuang, Tien Yow ^a   Chang, Wen Chi ^a   Lee, Liang Shong ^a,b,c   Huang, Wen Chung ^a,b   Cheng, Henrich ^a,b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

aFGF; Cervical root; Electromyography; Fibrin glue; Horseradish peroxidase retrograde axonal tracing; Regeneration

Indexed keywords

ACIDIC FIBROBLAST GROWTH FACTOR; FIBRIN GLUE; HORSERADISH PEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; CONVALESCENCE; CORRELATION ANALYSIS; DENERVATION; ELECTROMYOGRAPHY; ENZYMATIC ASSAY; FEMALE; GAIT; GROOMING; MOTONEURON; MOTOR PERFORMANCE; NERVE ANASTOMOSIS; NERVE CELL; NERVE REGENERATION; NERVE ROOT INJURY; NERVE TRANSECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD; STATISTICAL SIGNIFICANCE;

EID: 0344838674     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4886(02)00026-2     Document Type: Article

References (32)

1. Abercrombie M. Estimation of nuclear population from microtome sections. Anat, Rec. 94:1946;239-247.
2. Bertelli J.A., Mira J.C. Behavioral evaluating methods in the objective clinical assessment of motor function after experimental brachial plexus reconstruction in the rat. J. Neurosci. Methods. 46:1993;203-208.
3. Brunelli G., Brunelli L.M. Direct neurotization of severely damaged denervated muscles. Int. Surg. 65(6):1980;529-531.
4. Cai H., Wu W., So K.F., Prevette D.M., Oppenheim R.W. Long-term effects of a single dose of brain-derived neurotrophic factor on motoneuron survival following spinal root avulsion in the adult rat. Neurosci. Lett. 274(3):1999;147-150.
5. Carlstedt T., Grane P., Hallin R.G., Noren G. Return of function after spinal cord implantation of avulsed spinal nerve roots. Lancet. 346:1995;1323-1325.
6. Carlstedt T., Hallin R.G., Hedstrom K.G., Nilsson-Remahl I. Functional recovery in primates with brachial plexus injury after spinal cord implantation of avulsed ventral roots. J. Neurol. Neurosurg. Psychiatry. 56:1993;649-654.
7. Carlstedt T., Linda H., Cullheim S., Risling M. Reinnervation of hind limb muscles after ventral root avulsion and implantation in the lumbar spinal cord of the adult rat. Acta Physiol. Scand. 128:1989;645-646.
8. Carlstedt T., Noren G. Repair of ruptured spinal nerve roots in a brachial plexus lesion case report . J. Neurosurg. 82(4):1995;661-663.
9. Carlstedt T., Risling M., Lindå H., Cullhiem S., Ulfhake B. Regeneration after spinal nerve root injury. Restor. Neurol. Neurosci. 1:1990;289-295.
10. Cheng H., Almström S., Olson L. Fibrin glue used as an adhesive agent in CNS tissues. J. Neural Transplant. Plast. 5:1995;233-243.
11. Cheng H., Fraidakis M., Blombäck B., Lapchak P., Olson L., Hoffer B. Characterization of a fibrin glue-GDNF slow-release preparation. Cell Transplant. 7(1):1998;53-61.
12. Cheng H., Shoung H.M., Wu Z.A., Chen K.C., Lee L.S. Functional connectivity of the transected brachial plexus after intercostal neurotization in monkeys. J. Comp. Neurol. 380(2):1997;155-163.
13. Chuang D.C.C. Neurotization procedures for brachial plexus injuries. Hand Clin. 2:1995;633-645.
14. Chuang D.C.C., Chen H.C., Wei F.C. Restoration of shoulder abduction by nerve transfer in avulsed brachial plexus injuries - evaluation of 99 patients with different nerve transfers. Plast. Reconstr. Surg. 96:1995;122-128.
15. Chuang, T.Y., Huang, M.C., Chen, K.C., Chang, Y.C., Yen, Y.S., Lee, L.S., Cheng, H., 2002. Forelimb muscle activity following nerve graft repair of ventral roots in the rat cervical spinal cord. Life Sci., in press.
16. Cullheim S., Carlstedt T., Lindå H., Risling M., Ulfhake B. Motorneurons reinnervate skeletal muscle after ventral root implantation into the spinal cord of the cat. Neuroscience. 29:1989;725-733.
17. Giacobini M., Hoffer B., Zerbe G., Olson L. Acidic and basic fibroblast growth factors augment growth of fetal brain tissue grafts. Exp. Brain Res. 86:1991;73-81.
18. Glasby M.A., Hems T.E.J. Repairing spinal roots after brachial plexus injuries. Paraplegia. 33 (6):1995;359-361.
19. Gu Y., Spasic Z., Wu W. The effects of remaining axons on motoneuron survival and NOS expression following axotomy in the adult rat. Dev. Neurosci. 19(3):1997;255-259.
20. Guest J. The potential for human Schwann cell grafts to influence spinal cord regeneration in the nude rat, Ph.D. thesis. 1996;University of Miami, Miami, FL.
21. Hoffmann C.F.E., Marani E., Dijk J.G.V., Kamp W.V.D., Thomeer R.T.W.M. Reinnervation of avulsed and reimplanted ventral rootlets in the cervical spinal cord of the cat. J. Neurosurg. 84:1996;234-243.
22. Jamiesson A.M., Eames R.A. Reimplantation of avulsed brachial plexus roots an experimental study in dogs . Int. J. Microsurg. 2:1990;75-80.
23. Katoni P., Matsuda H., Suzuki T. Trial surgical procedure of nerve transfers to avulsion injuries of plexus brachialis. Excerpt. Med. Int. 12th Congress Ser. 291:1972;348-350.
24. Klasbrun M. The fibroblast growth factor family structural and biological properties . Prog. Growth Factor Res. 1:1989;207-235.
25. Leffert R. Surgery of the peripheral nerves and brachial plexus. Schmidek H.H., Sweet W.H. Operative Neurosurgical Techniques. 1983;1495-1540 Grune & Stratton, Orlando.
26. Narakas A.O. Injuries of the brachial plexus and neighboring peripheral nerves in vertebral fractures and other trauma of the cervical spine. Orthopade. 16(1):1987;81-86.
27. Narakas A.O. Lesions found when operating traction injuries of the brachial plexus. Clin. Neurol. Neurosurg. 95:(Suppl):1993;56-64.
28. Nishi R. Neurotrophic factors two are better than one . Science. 265:1994;1052-1053.
29. Novikova L., Novikov L., Kellerth J.O. Effects of neurotransplants and BDNF on the survival and regeneration of injured adult spinal motoneurons. Eur. J. Neurosci. 9(12):1997;2774-2777.
30. Risling M., Hildebrand C., Cullheim S. Invasion of the L7 ventral root and spinal pia mater by new axons after sciatic nerve division in kittens. Exp. Neurol. 83:1984;84-97.
31. Smith K., Kodama R. Reinnervation of denervated skeletal muscle by central neuron regenerating via ventral roots implanted into the spinal cord. Brain Res. Bull. 30:1991;447-451.
32. Yeoman P., Seddon H. Brachial plexus injuries treatment of flail arm . J. Bone Joint Surg. 43B:1961;493-499.