-
1
-
-
33749069523
-
SUMO1 haploinsufficiency leads to cleft lip and palate
-
Alkuraya F.S., Saadi I., Lund J.J., Turbe-Doan A., Morton C.C., and Maas R.L. SUMO1 haploinsufficiency leads to cleft lip and palate. Science 313 (2006) 1751
-
(2006)
Science
, vol.313
, pp. 1751
-
-
Alkuraya, F.S.1
Saadi, I.2
Lund, J.J.3
Turbe-Doan, A.4
Morton, C.C.5
Maas, R.L.6
-
2
-
-
25444517781
-
Ran-GTP regulates kinetochore attachment in somatic cells
-
Arnaoutov A., and Dasso M. Ran-GTP regulates kinetochore attachment in somatic cells. Cell Cycle 4 (2005) 1161-1165
-
(2005)
Cell Cycle
, vol.4
, pp. 1161-1165
-
-
Arnaoutov, A.1
Dasso, M.2
-
3
-
-
33750429598
-
RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism
-
Aslanukov A., Bhowmick R., Guruju M., Oswald J., Raz D., Bush R.A., Sieving P.A., Lu X., Bock C.B., and Ferreira P.A. RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism. PLoS Genet. 2 (2006) e177
-
(2006)
PLoS Genet.
, vol.2
-
-
Aslanukov, A.1
Bhowmick, R.2
Guruju, M.3
Oswald, J.4
Raz, D.5
Bush, R.A.6
Sieving, P.A.7
Lu, X.8
Bock, C.B.9
Ferreira, P.A.10
-
4
-
-
0035433114
-
Expression and regulation of the mammalian SUMO-1 E1 enzyme
-
Azuma Y., Tan S.H., Cavenagh M.M., Ainsztein A.M., Saitoh H., and Dasso M. Expression and regulation of the mammalian SUMO-1 E1 enzyme. FASEB J. 15 (2001) 1825-1827
-
(2001)
FASEB J.
, vol.15
, pp. 1825-1827
-
-
Azuma, Y.1
Tan, S.H.2
Cavenagh, M.M.3
Ainsztein, A.M.4
Saitoh, H.5
Dasso, M.6
-
5
-
-
0242509262
-
SUMO-2/3 regulates topoisomerase II in mitosis
-
Azuma Y., Arnaoutov A., and Dasso M. SUMO-2/3 regulates topoisomerase II in mitosis. J. Cell Biol. 163 (2003) 477-487
-
(2003)
J. Cell Biol.
, vol.163
, pp. 477-487
-
-
Azuma, Y.1
Arnaoutov, A.2
Dasso, M.3
-
6
-
-
21844437072
-
PIASy mediates SUMO-2 conjugation of Topoisomerase-II on mitotic chromosomes
-
Azuma Y., Arnaoutov A., Anan T., and Dasso M. PIASy mediates SUMO-2 conjugation of Topoisomerase-II on mitotic chromosomes. EMBO J. 24 (2005) 2172-2182
-
(2005)
EMBO J.
, vol.24
, pp. 2172-2182
-
-
Azuma, Y.1
Arnaoutov, A.2
Anan, T.3
Dasso, M.4
-
7
-
-
4744353220
-
Sumoylation increases HIF-1α stability and its transcriptional activity
-
Bae S.H., Jeong J.W., Park J.A., Kim S.H., Bae M.K., Choi S.J., and Kim K.W. Sumoylation increases HIF-1α stability and its transcriptional activity. Biochem. Biophys. Res. Commun. 324 (2004) 394-400
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.324
, pp. 394-400
-
-
Bae, S.H.1
Jeong, J.W.2
Park, J.A.3
Kim, S.H.4
Bae, M.K.5
Choi, S.J.6
Kim, K.W.7
-
8
-
-
0346422441
-
Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1
-
Bailey D., and O'Hare P. Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1. J. Biol. Chem. 279 (2004) 692-703
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 692-703
-
-
Bailey, D.1
O'Hare, P.2
-
10
-
-
38049187081
-
Induction of the SUMO-specific protease 1 transcription by the androgen receptor in prostate cancer cells
-
Bawa-Khalfe T., Cheng J., Wang Z., and Yeh E.T. Induction of the SUMO-specific protease 1 transcription by the androgen receptor in prostate cancer cells. J. Biol. Chem. 282 (2007) 37341-37349
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 37341-37349
-
-
Bawa-Khalfe, T.1
Cheng, J.2
Wang, Z.3
Yeh, E.T.4
-
11
-
-
0032504021
-
Structure determination of the small ubiquitin-related modifier SUMO-1
-
Bayer P., Arndt A., Metzger S., Mahajan R., Melchior F., Jaenicke R., and Becker J. Structure determination of the small ubiquitin-related modifier SUMO-1. J. Mol. Biol. 280 (1998) 275-286
-
(1998)
J. Mol. Biol.
, vol.280
, pp. 275-286
-
-
Bayer, P.1
Arndt, A.2
Metzger, S.3
Mahajan, R.4
Melchior, F.5
Jaenicke, R.6
Becker, J.7
-
12
-
-
1542781659
-
When cells get stressed: An integrative view of cellular senescence
-
Ben-Porath I., and Weinberg R.A. When cells get stressed: An integrative view of cellular senescence. J. Clin. Invest. 113 (2004) 8-13
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 8-13
-
-
Ben-Porath, I.1
Weinberg, R.A.2
-
13
-
-
0037033071
-
Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation
-
Bencsath K.P., Podgorski M.S., Pagala V.R., Slaughter C.A., and Schulman B.A. Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation. J. Biol. Chem. 277 (2002) 47938-47945
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47938-47945
-
-
Bencsath, K.P.1
Podgorski, M.S.2
Pagala, V.R.3
Slaughter, C.A.4
Schulman, B.A.5
-
14
-
-
33846914818
-
SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5
-
Benson M.D., Li Q.J., Kieckhafer K., Dudek D., Whorton M.R., Sunahara R.K., Iniguez-Lluhi J.A., and Martens J.R. SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5. Proc. Natl. Acad. Sci. USA 104 (2007) 1805-1810
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 1805-1810
-
-
Benson, M.D.1
Li, Q.J.2
Kieckhafer, K.3
Dudek, D.4
Whorton, M.R.5
Sunahara, R.K.6
Iniguez-Lluhi, J.A.7
Martens, J.R.8
-
15
-
-
1542374020
-
Nup358/RanBP2 attaches to the nuclear pore complex via association with Nup88 and Nup214/CAN and plays a supporting role in CRM1-mediated nuclear protein export
-
Bernad R., van der Velde H., Fornerod M., and Pickersgill H. Nup358/RanBP2 attaches to the nuclear pore complex via association with Nup88 and Nup214/CAN and plays a supporting role in CRM1-mediated nuclear protein export. Mol. Cell. Biol. 24 (2004) 2373-2384
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 2373-2384
-
-
Bernad, R.1
van der Velde, H.2
Fornerod, M.3
Pickersgill, H.4
-
16
-
-
34447249876
-
SUMOylation of hypoxia-inducible factor-1α reduces its transcriptional activity
-
Berta M.A., Mazure N., Hattab M., Pouyssegur J., and Brahimi-Horn M.C. SUMOylation of hypoxia-inducible factor-1α reduces its transcriptional activity. Biochem. Biophys. Res. Commun. 360 (2007) 646-652
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.360
, pp. 646-652
-
-
Berta, M.A.1
Mazure, N.2
Hattab, M.3
Pouyssegur, J.4
Brahimi-Horn, M.C.5
-
17
-
-
34047205692
-
SUMO is growing senescent
-
Bischof O., and Dejean A. SUMO is growing senescent. Cell Cycle 6 (2007) 677-681
-
(2007)
Cell Cycle
, vol.6
, pp. 677-681
-
-
Bischof, O.1
Dejean, A.2
-
18
-
-
33745210316
-
The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis
-
Bischof O., Schwamborn K., Martin N., Werner A., Sustmann C., Grosschedl R., and Dejean A. The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis. Mol. Cell 22 (2006) 783-794
-
(2006)
Mol. Cell
, vol.22
, pp. 783-794
-
-
Bischof, O.1
Schwamborn, K.2
Martin, N.3
Werner, A.4
Sustmann, C.5
Grosschedl, R.6
Dejean, A.7
-
19
-
-
0029736651
-
PIC1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia
-
Boddy M.N., Howe K., Etkin L.D., Solomon E., and Freemont P.S. PIC1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia. Oncogene 13 (1996) 971-982
-
(1996)
Oncogene
, vol.13
, pp. 971-982
-
-
Boddy, M.N.1
Howe, K.2
Etkin, L.D.3
Solomon, E.4
Freemont, P.S.5
-
20
-
-
4944255743
-
Post-translational modification of p53 in tumorigenesis
-
Bode A.M., and Dong Z. Post-translational modification of p53 in tumorigenesis. Nat. Rev. Cancer 4 (2004) 793-805
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 793-805
-
-
Bode, A.M.1
Dong, Z.2
-
21
-
-
34447560073
-
Targeting SUMO E1 to ubiquitin ligases: A viral strategy to counteract sumoylation
-
Boggio R., Passafaro A., and Chiocca S. Targeting SUMO E1 to ubiquitin ligases: A viral strategy to counteract sumoylation. J. Biol. Chem. 282 (2007) 15376-15382
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 15376-15382
-
-
Boggio, R.1
Passafaro, A.2
Chiocca, S.3
-
22
-
-
3042644131
-
A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus
-
Bohren K.M., Nadkarni V., Song J.H., Gabbay K.H., and Owerbach D. A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus. J. Biol. Chem. 279 (2004) 27233-27238
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27233-27238
-
-
Bohren, K.M.1
Nadkarni, V.2
Song, J.H.3
Gabbay, K.H.4
Owerbach, D.5
-
25
-
-
20144368274
-
High-resolution genome-wide mapping of genetic alterations in human glial brain tumors
-
Bredel M., Bredel C., Juric D., Harsh G.R., Vogel H., Recht L.D., and Sikic B.I. High-resolution genome-wide mapping of genetic alterations in human glial brain tumors. Cancer Res. 65 (2005) 4088-4096
-
(2005)
Cancer Res.
, vol.65
, pp. 4088-4096
-
-
Bredel, M.1
Bredel, C.2
Juric, D.3
Harsh, G.R.4
Vogel, H.5
Recht, L.D.6
Sikic, B.I.7
-
26
-
-
31544457877
-
p53 ubiquitination: Mdm2 and beyond
-
Brooks C.L., and Gu W. p53 ubiquitination: Mdm2 and beyond. Mol. Cell 21 (2006) 307-315
-
(2006)
Mol. Cell
, vol.21
, pp. 307-315
-
-
Brooks, C.L.1
Gu, W.2
-
27
-
-
35348904953
-
RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1α during hypoxia
-
Carbia-Nagashima A., Gerez J., Perez-Castro C., Paez-Pereda M., Silberstein S., Stalla G.K., Holsboer F., and Arzt E. RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1α during hypoxia. Cell 131 (2007) 309-323
-
(2007)
Cell
, vol.131
, pp. 309-323
-
-
Carbia-Nagashima, A.1
Gerez, J.2
Perez-Castro, C.3
Paez-Pereda, M.4
Silberstein, S.5
Stalla, G.K.6
Holsboer, F.7
Arzt, E.8
-
28
-
-
0037809267
-
Sumoylation of the progesterone receptor and of the steroid receptor coactivator SRC-1
-
Chauchereau A., Amazit L., Quesne M., Guiochon-Mantel A., and Milgrom E. Sumoylation of the progesterone receptor and of the steroid receptor coactivator SRC-1. J. Biol. Chem. 278 (2003) 12335-12343
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12335-12343
-
-
Chauchereau, A.1
Amazit, L.2
Quesne, M.3
Guiochon-Mantel, A.4
Milgrom, E.5
-
29
-
-
0030610686
-
3 exerts dose-dependent dual effects on APL cells
-
3 exerts dose-dependent dual effects on APL cells. Blood 89 (1997) 3345-3353
-
(1997)
Blood
, vol.89
, pp. 3345-3353
-
-
Chen, G.Q.1
Shi, X.G.2
Tang, W.3
Xiong, S.M.4
Zhu, J.5
Cai, X.6
Han, Z.G.7
Ni, J.H.8
Shi, G.Y.9
Jia, P.M.10
Liu, M.M.11
He, K.L.12
-
30
-
-
0041353442
-
MDM2-ARF complex regulates p53 sumoylation
-
Chen L., and Chen J. MDM2-ARF complex regulates p53 sumoylation. Oncogene 22 (2003) 5348-5357
-
(2003)
Oncogene
, vol.22
, pp. 5348-5357
-
-
Chen, L.1
Chen, J.2
-
31
-
-
2942735131
-
SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1
-
Cheng J., Wang D., Wang Z., and Yeh E.T. SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1. Mol. Cell. Biol. 24 (2004) 6021-6028
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 6021-6028
-
-
Cheng, J.1
Wang, D.2
Wang, Z.3
Yeh, E.T.4
-
32
-
-
17644421505
-
Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases
-
Cheng J., Perkins N.D., and Yeh E.T. Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases. J. Biol. Chem. 280 (2005) 14492-14498
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 14492-14498
-
-
Cheng, J.1
Perkins, N.D.2
Yeh, E.T.3
-
33
-
-
33748525164
-
Role of desumoylation in the development of prostate cancer
-
Cheng J., Bawa T., Lee P., Gong L., and Yeh E.T. Role of desumoylation in the development of prostate cancer. Neoplasia 8 (2006) 667-676
-
(2006)
Neoplasia
, vol.8
, pp. 667-676
-
-
Cheng, J.1
Bawa, T.2
Lee, P.3
Gong, L.4
Yeh, E.T.5
-
34
-
-
35548935098
-
SUMO-specific protease 1 is essential for stabilization of HIF1α during hypoxia
-
Cheng J., Kang X., Zhang S., and Yeh E.T. SUMO-specific protease 1 is essential for stabilization of HIF1α during hypoxia. Cell 131 (2007) 584-595
-
(2007)
Cell
, vol.131
, pp. 584-595
-
-
Cheng, J.1
Kang, X.2
Zhang, S.3
Yeh, E.T.4
-
35
-
-
33750089739
-
Negative modulation of RXRα transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1
-
Choi S.J., Chung S.S., Rho E.J., Lee H.W., Lee M.H., Choi H.S., Seol J.H., Baek S.H., Bang O.S., and Chung C.H. Negative modulation of RXRα transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1. J. Biol. Chem. 281 (2006) 30669-30677
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30669-30677
-
-
Choi, S.J.1
Chung, S.S.2
Rho, E.J.3
Lee, H.W.4
Lee, M.H.5
Choi, H.S.6
Seol, J.H.7
Baek, S.H.8
Bang, O.S.9
Chung, C.H.10
-
36
-
-
0033179197
-
Pictures in cell biology. Structures of nuclear-transport components
-
Chook Y.M., Cingolani G., Conti E., Stewart M., Vetter I., and Wittinghofer A. Pictures in cell biology. Structures of nuclear-transport components. Trends Cell Biol. 9 (1999) 310-311
-
(1999)
Trends Cell Biol.
, vol.9
, pp. 310-311
-
-
Chook, Y.M.1
Cingolani, G.2
Conti, E.3
Stewart, M.4
Vetter, I.5
Wittinghofer, A.6
-
37
-
-
0032535483
-
The ubiquitin-proteasome pathway: On protein death and cell life
-
Ciechanover A. The ubiquitin-proteasome pathway: On protein death and cell life. EMBO J. 17 (1998) 7151-7160
-
(1998)
EMBO J.
, vol.17
, pp. 7151-7160
-
-
Ciechanover, A.1
-
38
-
-
29244485921
-
The senescent side of tumor suppression
-
Collado M., and Serrano M. The senescent side of tumor suppression. Cell Cycle 4 (2005) 1722-1724
-
(2005)
Cell Cycle
, vol.4
, pp. 1722-1724
-
-
Collado, M.1
Serrano, M.2
-
39
-
-
2942682654
-
Modification of the erythroid transcription factor GATA-1 by SUMO-1
-
Collavin L., Gostissa M., Avolio F., Secco P., Ronchi A., Santoro C., and Del S.G. Modification of the erythroid transcription factor GATA-1 by SUMO-1. Proc. Natl. Acad. Sci. USA 101 (2004) 8870-8875
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8870-8875
-
-
Collavin, L.1
Gostissa, M.2
Avolio, F.3
Secco, P.4
Ronchi, A.5
Santoro, C.6
Del, S.G.7
-
40
-
-
0037417957
-
Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia
-
Comerford K.M., Leonard M.O., Karhausen J., Carey R., Colgan S.P., and Taylor C.T. Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia. Proc. Natl. Acad. Sci. USA 100 (2003) 986-991
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 986-991
-
-
Comerford, K.M.1
Leonard, M.O.2
Karhausen, J.3
Carey, R.4
Colgan, S.P.5
Taylor, C.T.6
-
41
-
-
0037351924
-
Transactivation properties of c-Myb are critically dependent on two SUMO-1 acceptor sites that are conjugated in a PIASy enhanced manner
-
Dahle O., Andersen T.O., Nordgard O., Matre V., Del S.G., and Gabrielsen O.S. Transactivation properties of c-Myb are critically dependent on two SUMO-1 acceptor sites that are conjugated in a PIASy enhanced manner. Eur. J. Biochem. 270 (2003) 1338-1348
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 1338-1348
-
-
Dahle, O.1
Andersen, T.O.2
Nordgard, O.3
Matre, V.4
Del, S.G.5
Gabrielsen, O.S.6
-
42
-
-
33748522684
-
Balance of Yin and Yang: Ubiquitylation-mediated regulation of p53 and c-Myc
-
Dai M.S., Jin Y., Gallegos J.R., and Lu H. Balance of Yin and Yang: Ubiquitylation-mediated regulation of p53 and c-Myc. Neoplasia 8 (2006) 630-644
-
(2006)
Neoplasia
, vol.8
, pp. 630-644
-
-
Dai, M.S.1
Jin, Y.2
Gallegos, J.R.3
Lu, H.4
-
43
-
-
36849096094
-
Phosphorylation-dependent antagonism of sumoylation derepresses progesterone receptor action in breast cancer cells
-
Daniel A.R., Faivre E.J., and Lange C.A. Phosphorylation-dependent antagonism of sumoylation derepresses progesterone receptor action in breast cancer cells. Mol. Endocrinol. 21 (2007) 2890-2906
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 2890-2906
-
-
Daniel, A.R.1
Faivre, E.J.2
Lange, C.A.3
-
44
-
-
40749131181
-
Emerging roles of the SUMO pathway in mitosis
-
Dasso M. Emerging roles of the SUMO pathway in mitosis. Cell Div. 3 (2008) 5
-
(2008)
Cell Div.
, vol.3
, pp. 5
-
-
Dasso, M.1
-
45
-
-
33748476338
-
Gene targeting methods for studying nuclear transport factors in mice
-
Dawlaty M.M., and van Deursen J.M. Gene targeting methods for studying nuclear transport factors in mice. Methods 39 (2006) 370-378
-
(2006)
Methods
, vol.39
, pp. 370-378
-
-
Dawlaty, M.M.1
van Deursen, J.M.2
-
46
-
-
41149146735
-
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIα
-
Dawlaty M.M., Malureanu L., Jeganathan K.B., Kao E., Sustmann C., Tahk S., Shuai K., Grosschedl R., and van Deursen J.M. Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIα. Cell 133 (2008) 103-115
-
(2008)
Cell
, vol.133
, pp. 103-115
-
-
Dawlaty, M.M.1
Malureanu, L.2
Jeganathan, K.B.3
Kao, E.4
Sustmann, C.5
Tahk, S.6
Shuai, K.7
Grosschedl, R.8
van Deursen, J.M.9
-
47
-
-
34248209648
-
PIASy-mediated sumoylation of Yin Yang 1 depends on their interaction but not the RING finger
-
Deng Z., Wan M., and Sui G. PIASy-mediated sumoylation of Yin Yang 1 depends on their interaction but not the RING finger. Mol. Cell. Biol. 27 (2007) 3780-3792
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 3780-3792
-
-
Deng, Z.1
Wan, M.2
Sui, G.3
-
48
-
-
0030728212
-
Ubch9 conjugates SUMO but not ubiquitin
-
Desterro J.M., Thomson J., and Hay R.T. Ubch9 conjugates SUMO but not ubiquitin. FEBS Lett. 417 (1997) 297-300
-
(1997)
FEBS Lett.
, vol.417
, pp. 297-300
-
-
Desterro, J.M.1
Thomson, J.2
Hay, R.T.3
-
49
-
-
0032135131
-
SUMO-1 modification of IκBα inhibits NF-κB activation
-
Desterro J.M., Rodriguez M.S., and Hay R.T. SUMO-1 modification of IκBα inhibits NF-κB activation. Mol. Cell 2 (1998) 233-239
-
(1998)
Mol. Cell
, vol.2
, pp. 233-239
-
-
Desterro, J.M.1
Rodriguez, M.S.2
Hay, R.T.3
-
50
-
-
0033537828
-
Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1
-
Desterro J.M., Rodriguez M.S., Kemp G.D., and Hay R.T. Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1. J. Biol. Chem. 274 (1999) 10618-10624
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10618-10624
-
-
Desterro, J.M.1
Rodriguez, M.S.2
Kemp, G.D.3
Hay, R.T.4
-
51
-
-
33745049415
-
The SUMO-specific protease SENP5 is required for cell division
-
Di B.A., Ouyang J., Lee H.Y., Catic A., Ploegh H., and Gill G. The SUMO-specific protease SENP5 is required for cell division. Mol. Cell. Biol. 26 (2006) 4489-4498
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 4489-4498
-
-
Di, B.A.1
Ouyang, J.2
Lee, H.Y.3
Catic, A.4
Ploegh, H.5
Gill, G.6
-
52
-
-
54949126326
-
PIASγ is required for faithful chromosome segregation in human cells
-
Diaz-Martinez L.A., Gimenez-Abian J.F., Azuma Y., Guacci V., Gimenez-Martin G., Lanier L.M., and Clarke D.J. PIASγ is required for faithful chromosome segregation in human cells. PLoS ONE 1 (2006) e53
-
(2006)
PLoS ONE
, vol.1
-
-
Diaz-Martinez, L.A.1
Gimenez-Abian, J.F.2
Azuma, Y.3
Guacci, V.4
Gimenez-Martin, G.5
Lanier, L.M.6
Clarke, D.J.7
-
53
-
-
0029048985
-
KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2
-
Dong J.T., Lamb P.W., Rinker-Schaeffer C.W., Vukanovic J., Ichikawa T., Isaacs J.T., and Barrett J.C. KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2. Science 268 (1995) 884-886
-
(1995)
Science
, vol.268
, pp. 884-886
-
-
Dong, J.T.1
Lamb, P.W.2
Rinker-Schaeffer, C.W.3
Vukanovic, J.4
Ichikawa, T.5
Isaacs, J.T.6
Barrett, J.C.7
-
54
-
-
0029740215
-
Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss
-
Dong J.T., Suzuki H., Pin S.S., Bova G.S., Schalken J.A., Isaacs W.B., Barrett J.C., and Isaacs J.T. Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss. Cancer Res. 56 (1996) 4387-4390
-
(1996)
Cancer Res.
, vol.56
, pp. 4387-4390
-
-
Dong, J.T.1
Suzuki, H.2
Pin, S.S.3
Bova, G.S.4
Schalken, J.A.5
Isaacs, W.B.6
Barrett, J.C.7
Isaacs, J.T.8
-
55
-
-
58149347461
-
DeSUMOylating enzymes-SENPs
-
Drag M., and Salvesen G.S. DeSUMOylating enzymes-SENPs. IUBMB Life 60 (2008) 734-742
-
(2008)
IUBMB Life
, vol.60
, pp. 734-742
-
-
Drag, M.1
Salvesen, G.S.2
-
56
-
-
0032547959
-
The Drosophila semushi mutation blocks nuclear import of bicoid during embryogenesis
-
Epps J.L., and Tanda S. The Drosophila semushi mutation blocks nuclear import of bicoid during embryogenesis. Curr. Biol. 8 (1998) 1277-1280
-
(1998)
Curr. Biol.
, vol.8
, pp. 1277-1280
-
-
Epps, J.L.1
Tanda, S.2
-
57
-
-
0035969103
-
DNA viruses and viral proteins that interact with PML nuclear bodies
-
Everett R.D. DNA viruses and viral proteins that interact with PML nuclear bodies. Oncogene 20 (2001) 7266-7273
-
(2001)
Oncogene
, vol.20
, pp. 7266-7273
-
-
Everett, R.D.1
-
59
-
-
23044466047
-
Specificity and versatility in TGF-β signaling through Smads
-
Feng X.H., and Derynck R. Specificity and versatility in TGF-β signaling through Smads. Annu. Rev. Cell Dev. Biol. 21 (2005) 659-693
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 659-693
-
-
Feng, X.H.1
Derynck, R.2
-
60
-
-
24644522876
-
Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3
-
Fu C., Ahmed K., Ding H., Ding X., Lan J., Yang Z., Miao Y., Zhu Y., Shi Y., Zhu J., Huang H., and Yao X. Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3. Oncogene 24 (2005) 5401-5413
-
(2005)
Oncogene
, vol.24
, pp. 5401-5413
-
-
Fu, C.1
Ahmed, K.2
Ding, H.3
Ding, X.4
Lan, J.5
Yang, Z.6
Miao, Y.7
Zhu, Y.8
Shi, Y.9
Zhu, J.10
Huang, H.11
Yao, X.12
-
62
-
-
33845970925
-
Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARγ
-
Ghisletti S., Huang W., Ogawa S., Pascual G., Lin M.E., Willson T.M., Rosenfeld M.G., and Glass C.K. Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARγ. Mol. Cell 25 (2007) 57-70
-
(2007)
Mol. Cell
, vol.25
, pp. 57-70
-
-
Ghisletti, S.1
Huang, W.2
Ogawa, S.3
Pascual, G.4
Lin, M.E.5
Willson, T.M.6
Rosenfeld, M.G.7
Glass, C.K.8
-
63
-
-
0037961625
-
P300 transcriptional repression is mediated by SUMO modification
-
Girdwood D., Bumpass D., Vaughan O.A., Thain A., Anderson L.A., Snowden A.W., Garcia-Wilson E., Perkins N.D., and Hay R.T. P300 transcriptional repression is mediated by SUMO modification. Mol. Cell 11 (2003) 1043-1054
-
(2003)
Mol. Cell
, vol.11
, pp. 1043-1054
-
-
Girdwood, D.1
Bumpass, D.2
Vaughan, O.A.3
Thain, A.4
Anderson, L.A.5
Snowden, A.W.6
Garcia-Wilson, E.7
Perkins, N.D.8
Hay, R.T.9
-
64
-
-
33744917849
-
Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3
-
Gong L., and Yeh E.T. Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3. J. Biol. Chem. 281 (2006) 15869-15877
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15869-15877
-
-
Gong, L.1
Yeh, E.T.2
-
65
-
-
0034603179
-
Differential regulation of sentrinized proteins by a novel sentrin-specific protease
-
Gong L., Millas S., Maul G.G., and Yeh E.T. Differential regulation of sentrinized proteins by a novel sentrin-specific protease. J. Biol. Chem. 275 (2000) 3355-3359
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3355-3359
-
-
Gong, L.1
Millas, S.2
Maul, G.G.3
Yeh, E.T.4
-
66
-
-
0033570892
-
Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1
-
Gostissa M., Hengstermann A., Fogal V., Sandy P., Schwarz S.E., Scheffner M., and Del S.G. Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1. EMBO J. 18 (1999) 6462-6471
-
(1999)
EMBO J.
, vol.18
, pp. 6462-6471
-
-
Gostissa, M.1
Hengstermann, A.2
Fogal, V.3
Sandy, P.4
Schwarz, S.E.5
Scheffner, M.6
Del, S.G.7
-
67
-
-
14844344773
-
Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors
-
Gregoire S., and Yang X.J. Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors. Mol. Cell. Biol. 25 (2005) 2273-2287
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 2273-2287
-
-
Gregoire, S.1
Yang, X.J.2
-
68
-
-
3543046736
-
A functional variant of SUMO4, a new IκBα modifier, is associated with type 1 diabetes
-
Guo D., Li M., Zhang Y., Yang P., Eckenrode S., Hopkins D., Zheng W., Purohit S., Podolsky R.H., Muir A., Wang J., Dong Z., et al. A functional variant of SUMO4, a new IκBα modifier, is associated with type 1 diabetes. Nat. Genet. 36 (2004) 837-841
-
(2004)
Nat. Genet.
, vol.36
, pp. 837-841
-
-
Guo, D.1
Li, M.2
Zhang, Y.3
Yang, P.4
Eckenrode, S.5
Hopkins, D.6
Zheng, W.7
Purohit, S.8
Podolsky, R.H.9
Muir, A.10
Wang, J.11
Dong, Z.12
-
69
-
-
27144482996
-
Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress
-
Guo D., Han J., Adam B.L., Colburn N.H., Wang M.H., Dong Z., Eizirik D.L., She J.X., and Wang C.Y. Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. Biochem. Biophys. Res. Commun. 337 (2005) 1308-1318
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.337
, pp. 1308-1318
-
-
Guo, D.1
Han, J.2
Adam, B.L.3
Colburn, N.H.4
Wang, M.H.5
Dong, Z.6
Eizirik, D.L.7
She, J.X.8
Wang, C.Y.9
-
70
-
-
33751252276
-
Cancer metastasis: Building a framework
-
Gupta G.P., and Massague J. Cancer metastasis: Building a framework. Cell 127 (2006) 679-695
-
(2006)
Cell
, vol.127
, pp. 679-695
-
-
Gupta, G.P.1
Massague, J.2
-
71
-
-
27144529182
-
Ubiquitylation and cell signaling
-
Haglund K., and Dikic I. Ubiquitylation and cell signaling. EMBO J. 24 (2005) 3353-3359
-
(2005)
EMBO J.
, vol.24
, pp. 3353-3359
-
-
Haglund, K.1
Dikic, I.2
-
72
-
-
40249105993
-
The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing
-
Haindl M., Harasim T., Eick D., and Muller S. The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing. EMBO Rep. 9 (2008) 273-279
-
(2008)
EMBO Rep.
, vol.9
, pp. 273-279
-
-
Haindl, M.1
Harasim, T.2
Eick, D.3
Muller, S.4
-
73
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
74
-
-
0037205460
-
Association of the human SUMO-1 protease SENP2 with the nuclear pore
-
Hang J., and Dasso M. Association of the human SUMO-1 protease SENP2 with the nuclear pore. J. Biol. Chem. 277 (2002) 19961-19966
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19961-19966
-
-
Hang, J.1
Dasso, M.2
-
75
-
-
14244260623
-
Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae
-
Hannich J.T., Lewis A., Kroetz M.B., Li S.J., Heide H., Emili A., and Hochstrasser M. Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J. Biol. Chem. 280 (2005) 4102-4110
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 4102-4110
-
-
Hannich, J.T.1
Lewis, A.2
Kroetz, M.B.3
Li, S.J.4
Heide, H.5
Emili, A.6
Hochstrasser, M.7
-
76
-
-
1542380494
-
Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission
-
Harder Z., Zunino R., and McBride H. Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission. Curr. Biol. 14 (2004) 340-345
-
(2004)
Curr. Biol.
, vol.14
, pp. 340-345
-
-
Harder, Z.1
Zunino, R.2
McBride, H.3
-
77
-
-
15944406765
-
SUMO: A history of modification
-
Hay R.T. SUMO: A history of modification. Mol. Cell 18 (2005) 1-12
-
(2005)
Mol. Cell
, vol.18
, pp. 1-12
-
-
Hay, R.T.1
-
78
-
-
34548483908
-
SUMO-specific proteases: A twist in the tail
-
Hay R.T. SUMO-specific proteases: A twist in the tail. Trends Cell Biol. 17 (2007) 370-376
-
(2007)
Trends Cell Biol.
, vol.17
, pp. 370-376
-
-
Hay, R.T.1
-
80
-
-
0035293622
-
Protein regulation by monoubiquitin
-
Hicke L. Protein regulation by monoubiquitin. Nat. Rev. Mol. Cell Biol. 2 (2001) 195-201
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 195-201
-
-
Hicke, L.1
-
81
-
-
0037385213
-
Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1
-
Hietakangas V., Ahlskog J.K., Jakobsson A.M., Hellesuo M., Sahlberg N.M., Holmberg C.I., Mikhailov A., Palvimo J.J., Pirkkala L., and Sistonen L. Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1. Mol. Cell. Biol. 23 (2003) 2953-2968
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 2953-2968
-
-
Hietakangas, V.1
Ahlskog, J.K.2
Jakobsson, A.M.3
Hellesuo, M.4
Sahlberg, N.M.5
Holmberg, C.I.6
Mikhailov, A.7
Palvimo, J.J.8
Pirkkala, L.9
Sistonen, L.10
-
82
-
-
30444440554
-
PDSM, a motif for phosphorylation-dependent SUMO modification
-
Hietakangas V., Anckar J., Blomster H.A., Fujimoto M., Palvimo J.J., Nakai A., and Sistonen L. PDSM, a motif for phosphorylation-dependent SUMO modification. Proc. Natl. Acad. Sci. USA 103 (2006) 45-50
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 45-50
-
-
Hietakangas, V.1
Anckar, J.2
Blomster, H.A.3
Fujimoto, M.4
Palvimo, J.J.5
Nakai, A.6
Sistonen, L.7
-
83
-
-
0030457014
-
Ubiquitin-dependent protein degradation
-
Hochstrasser M. Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30 (1996) 405-439
-
(1996)
Annu. Rev. Genet.
, vol.30
, pp. 405-439
-
-
Hochstrasser, M.1
-
84
-
-
0035812848
-
SP-RING for SUMO: New functions bloom for a ubiquitin-like protein
-
Hochstrasser M. SP-RING for SUMO: New functions bloom for a ubiquitin-like protein. Cell 107 (2001) 5-8
-
(2001)
Cell
, vol.107
, pp. 5-8
-
-
Hochstrasser, M.1
-
85
-
-
0032493368
-
Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway
-
Huang L.E., Gu J., Schau M., and Bunn H.F. Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway. Proc. Natl. Acad. Sci. USA 95 (1998) 7987-7992
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7987-7992
-
-
Huang, L.E.1
Gu, J.2
Schau, M.3
Bunn, H.F.4
-
86
-
-
0344305376
-
Sequential modification of NEMO/IKKγ by SUMO-1 and ubiquitin mediates NF-κB activation by genotoxic stress
-
Huang T.T., Wuerzberger-Davis S.M., Wu Z.H., and Miyamoto S. Sequential modification of NEMO/IKKγ by SUMO-1 and ubiquitin mediates NF-κB activation by genotoxic stress. Cell 115 (2003) 565-576
-
(2003)
Cell
, vol.115
, pp. 565-576
-
-
Huang, T.T.1
Wuerzberger-Davis, S.M.2
Wu, Z.H.3
Miyamoto, S.4
-
87
-
-
7044269671
-
Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution: Implication on the functional differences of SUMO proteins
-
Huang W.C., Ko T.P., Li S.S., and Wang A.H. Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution: Implication on the functional differences of SUMO proteins. Eur. J. Biochem. 271 (2004) 4114-4122
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 4114-4122
-
-
Huang, W.C.1
Ko, T.P.2
Li, S.S.3
Wang, A.H.4
-
88
-
-
36749010218
-
The age of crosstalk: Phosphorylation, ubiquitination, and beyond
-
Hunter T. The age of crosstalk: Phosphorylation, ubiquitination, and beyond. Mol. Cell 28 (2007) 730-738
-
(2007)
Mol. Cell
, vol.28
, pp. 730-738
-
-
Hunter, T.1
-
89
-
-
33748657386
-
Nup214 is required for CRM1-dependent nuclear protein export in vivo
-
Hutten S., and Kehlenbach R.H. Nup214 is required for CRM1-dependent nuclear protein export in vivo. Mol. Cell. Biol. 26 (2006) 6772-6785
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 6772-6785
-
-
Hutten, S.1
Kehlenbach, R.H.2
-
90
-
-
33745046562
-
Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2
-
Itahana Y., Yeh E.T., and Zhang Y. Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2. Mol. Cell. Biol. 26 (2006) 4675-4689
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 4675-4689
-
-
Itahana, Y.1
Yeh, E.T.2
Zhang, Y.3
-
91
-
-
0030826334
-
Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p
-
Johnson E.S., and Blobel G. Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p. J. Biol. Chem. 272 (1997) 26799-26802
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26799-26802
-
-
Johnson, E.S.1
Blobel, G.2
-
92
-
-
0030794729
-
The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer
-
Johnson E.S., Schwienhorst I., Dohmen R.J., and Blobel G. The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J. 16 (1997) 5509-5519
-
(1997)
EMBO J.
, vol.16
, pp. 5509-5519
-
-
Johnson, E.S.1
Schwienhorst, I.2
Dohmen, R.J.3
Blobel, G.4
-
93
-
-
18844465487
-
Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: Ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteins
-
RESEARCH0002
-
Jones D., Crowe E., Stevens T.A., and Candido E.P. Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: Ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteins. Genome Biol. 3 (2002) RESEARCH0002
-
(2002)
Genome Biol.
, vol.3
-
-
Jones, D.1
Crowe, E.2
Stevens, T.A.3
Candido, E.P.4
-
94
-
-
33750806731
-
Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone
-
Jones M.C., Fusi L., Higham J.H., bdel-Hafiz H., Horwitz K.B., Lam E.W., and Brosens J.J. Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone. Proc. Natl. Acad. Sci. USA 103 (2006) 16272-16277
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 16272-16277
-
-
Jones, M.C.1
Fusi, L.2
Higham, J.H.3
bdel-Hafiz, H.4
Horwitz, K.B.5
Lam, E.W.6
Brosens, J.J.7
-
95
-
-
0037128207
-
SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles
-
Joseph J., Tan S.H., Karpova T.S., McNally J.G., and Dasso M. SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles. J. Cell Biol. 156 (2002) 595-602
-
(2002)
J. Cell Biol.
, vol.156
, pp. 595-602
-
-
Joseph, J.1
Tan, S.H.2
Karpova, T.S.3
McNally, J.G.4
Dasso, M.5
-
96
-
-
0037324340
-
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
-
Joseph S.B., Castrillo A., Laffitte B.A., Mangelsdorf D.J., and Tontonoz P. Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat. Med. 9 (2003) 213-219
-
(2003)
Nat. Med.
, vol.9
, pp. 213-219
-
-
Joseph, S.B.1
Castrillo, A.2
Laffitte, B.A.3
Mangelsdorf, D.J.4
Tontonoz, P.5
-
97
-
-
1842715846
-
The RanGAP1-RanBP2 complex is essential for microtubule-kinetochore interactions in vivo
-
Joseph J., Liu S.T., Jablonski S.A., Yen T.J., and Dasso M. The RanGAP1-RanBP2 complex is essential for microtubule-kinetochore interactions in vivo. Curr. Biol. 14 (2004) 611-617
-
(2004)
Curr. Biol.
, vol.14
, pp. 611-617
-
-
Joseph, J.1
Liu, S.T.2
Jablonski, S.A.3
Yen, T.J.4
Dasso, M.5
-
98
-
-
0037418829
-
The polycomb protein Pc2 is a SUMO E3
-
Kagey M.H., Melhuish T.A., and Wotton D. The polycomb protein Pc2 is a SUMO E3. Cell 113 (2003) 127-137
-
(2003)
Cell
, vol.113
, pp. 127-137
-
-
Kagey, M.H.1
Melhuish, T.A.2
Wotton, D.3
-
99
-
-
0034789730
-
Involvement of PIAS1 in the sumoylation of tumor suppressor p53
-
Kahyo T., Nishida T., and Yasuda H. Involvement of PIAS1 in the sumoylation of tumor suppressor p53. Mol. Cell 8 (2001) 713-718
-
(2001)
Mol. Cell
, vol.8
, pp. 713-718
-
-
Kahyo, T.1
Nishida, T.2
Yasuda, H.3
-
100
-
-
44649163272
-
The type I TGF-β receptor is covalently modified and regulated by sumoylation
-
Kang J.S., Saunier E.F., Akhurst R.J., and Derynck R. The type I TGF-β receptor is covalently modified and regulated by sumoylation. Nat. Cell Biol. 10 (2008) 654-664
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 654-664
-
-
Kang, J.S.1
Saunier, E.F.2
Akhurst, R.J.3
Derynck, R.4
-
101
-
-
33744978564
-
NF-κB and cancer: Mechanisms and targets
-
Karin M. NF-κB and cancer: Mechanisms and targets. Mol. Carcinog. 45 (2006) 355-361
-
(2006)
Mol. Carcinog.
, vol.45
, pp. 355-361
-
-
Karin, M.1
-
102
-
-
33745298519
-
Nuclear factor-κB in cancer development and progression
-
Karin M. Nuclear factor-κB in cancer development and progression. Nature 441 (2006) 431-436
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
103
-
-
50149112651
-
ZNF451 is a novel PML body- and SUMO-associated transcriptional coregulator
-
Karvonen U., Jaaskelainen T., Rytinki M., Kaikkonen S., and Palvimo J.J. ZNF451 is a novel PML body- and SUMO-associated transcriptional coregulator. J. Mol. Biol. 382 (2008) 585-600
-
(2008)
J. Mol. Biol.
, vol.382
, pp. 585-600
-
-
Karvonen, U.1
Jaaskelainen, T.2
Rytinki, M.3
Kaikkonen, S.4
Palvimo, J.J.5
-
104
-
-
38449103757
-
Overexpression of small ubiquitin-related modifier-1 and sumoylated Mdm2 in oral squamous cell carcinoma: Possible involvement in tumor proliferation and prognosis
-
Katayama A., Ogino T., Bandoh N., Takahara M., Kishibe K., Nonaka S., and Harabuchi Y. Overexpression of small ubiquitin-related modifier-1 and sumoylated Mdm2 in oral squamous cell carcinoma: Possible involvement in tumor proliferation and prognosis. Int. J. Oncol. 31 (2007) 517-524
-
(2007)
Int. J. Oncol.
, vol.31
, pp. 517-524
-
-
Katayama, A.1
Ogino, T.2
Bandoh, N.3
Takahara, M.4
Kishibe, K.5
Nonaka, S.6
Harabuchi, Y.7
-
105
-
-
0030851491
-
Location of KAI1 on the short arm of human chromosome 11 and frequency of allelic loss in advanced human prostate cancer
-
Kawana Y., Komiya A., Ueda T., Nihei N., Kuramochi H., Suzuki H., Yatani R., Imai T., Dong J.T., Imai T., Yoshie O., Barrett J.C., et al. Location of KAI1 on the short arm of human chromosome 11 and frequency of allelic loss in advanced human prostate cancer. Prostate 32 (1997) 205-213
-
(1997)
Prostate
, vol.32
, pp. 205-213
-
-
Kawana, Y.1
Komiya, A.2
Ueda, T.3
Nihei, N.4
Kuramochi, H.5
Suzuki, H.6
Yatani, R.7
Imai, T.8
Dong, J.T.9
Imai, T.10
Yoshie, O.11
Barrett, J.C.12
-
107
-
-
33846087335
-
SUMOylation code in cancer development and metastasis
-
Kim K.I., and Baek S.H. SUMOylation code in cancer development and metastasis. Mol. Cells 22 (2006) 247-253
-
(2006)
Mol. Cells
, vol.22
, pp. 247-253
-
-
Kim, K.I.1
Baek, S.H.2
-
108
-
-
0001720254
-
A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs
-
Kim K.I., Baek S.H., Jeon Y.J., Nishimori S., Suzuki T., Uchida S., Shimbara N., Saitoh H., Tanaka K., and Chung C.H. A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs. J. Biol. Chem. 275 (2000) 14102-14106
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14102-14106
-
-
Kim, K.I.1
Baek, S.H.2
Jeon, Y.J.3
Nishimori, S.4
Suzuki, T.5
Uchida, S.6
Shimbara, N.7
Saitoh, H.8
Tanaka, K.9
Chung, C.H.10
-
109
-
-
17244378084
-
Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes
-
Kim J.H., Kim B., Cai L., Choi H.J., Ohgi K.A., Tran C., Chen C., Chung C.H., Huber O., Rose D.W., Sawyers C.L., et al. Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes. Nature 434 (2005) 921-926
-
(2005)
Nature
, vol.434
, pp. 921-926
-
-
Kim, J.H.1
Kim, B.2
Cai, L.3
Choi, H.J.4
Ohgi, K.A.5
Tran, C.6
Chen, C.7
Chung, C.H.8
Huber, O.9
Rose, D.W.10
Sawyers, C.L.11
-
110
-
-
27544498904
-
Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1
-
Kim Y.H., Sung K.S., Lee S.J., Kim Y.O., Choi C.Y., and Kim Y. Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1. FEBS Lett. 579 (2005) 6272-6278
-
(2005)
FEBS Lett.
, vol.579
, pp. 6272-6278
-
-
Kim, Y.H.1
Sung, K.S.2
Lee, S.J.3
Kim, Y.O.4
Choi, C.Y.5
Kim, Y.6
-
111
-
-
33744783406
-
Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis
-
Kim J.H., Choi H.J., Kim B., Kim M.H., Lee J.M., Kim I.S., Lee M.H., Choi S.J., Kim K.I., Kim S.I., Chung C.H., and Baek S.H. Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis. Nat. Cell Biol. 8 (2006) 631-639
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 631-639
-
-
Kim, J.H.1
Choi, H.J.2
Kim, B.3
Kim, M.H.4
Lee, J.M.5
Kim, I.S.6
Lee, M.H.7
Choi, S.J.8
Kim, K.I.9
Kim, S.I.10
Chung, C.H.11
Baek, S.H.12
-
112
-
-
38049181050
-
SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells
-
Kim J.H., Lee J.M., Nam H.J., Choi H.J., Yang J.W., Lee J.S., Kim M.H., Kim S.I., Chung C.H., Kim K.I., and Baek S.H. SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells. Proc. Natl. Acad. Sci. USA 104 (2007) 20793-20798
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 20793-20798
-
-
Kim, J.H.1
Lee, J.M.2
Nam, H.J.3
Choi, H.J.4
Yang, J.W.5
Lee, J.S.6
Kim, M.H.7
Kim, S.I.8
Chung, C.H.9
Kim, K.I.10
Baek, S.H.11
-
113
-
-
18444370302
-
The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase
-
Kirsh O., Seeler J.S., Pichler A., Gast A., Muller S., Miska E., Mathieu M., Harel-Bellan A., Kouzarides T., Melchior F., and Dejean A. The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase. EMBO J. 21 (2002) 2682-2691
-
(2002)
EMBO J.
, vol.21
, pp. 2682-2691
-
-
Kirsh, O.1
Seeler, J.S.2
Pichler, A.3
Gast, A.4
Muller, S.5
Miska, E.6
Mathieu, M.7
Harel-Bellan, A.8
Kouzarides, T.9
Melchior, F.10
Dejean, A.11
-
114
-
-
48349117947
-
Ubc9 sumoylation regulates SUMO target discrimination
-
Knipscheer P., Flotho A., Klug H., Olsen J.V., van Dijk W.J., Fish A., Johnson E.S., Mann M., Sixma T.K., and Pichler A. Ubc9 sumoylation regulates SUMO target discrimination. Mol. Cell 31 (2008) 371-382
-
(2008)
Mol. Cell
, vol.31
, pp. 371-382
-
-
Knipscheer, P.1
Flotho, A.2
Klug, H.3
Olsen, J.V.4
van Dijk, W.J.5
Fish, A.6
Johnson, E.S.7
Mann, M.8
Sixma, T.K.9
Pichler, A.10
-
115
-
-
0036291475
-
PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases
-
Kotaja N., Karvonen U., Janne O.A., and Palvimo J.J. PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases. Mol. Cell. Biol. 22 (2002) 5222-5234
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5222-5234
-
-
Kotaja, N.1
Karvonen, U.2
Janne, O.A.3
Palvimo, J.J.4
-
116
-
-
0037119457
-
The nuclear receptor interaction domain of GRIP1 is modulated by covalent attachment of SUMO-1
-
Kotaja N., Karvonen U., Janne O.A., and Palvimo J.J. The nuclear receptor interaction domain of GRIP1 is modulated by covalent attachment of SUMO-1. J. Biol. Chem. 277 (2002) 30283-30288
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30283-30288
-
-
Kotaja, N.1
Karvonen, U.2
Janne, O.A.3
Palvimo, J.J.4
-
117
-
-
28044437730
-
SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx
-
Kuo H.Y., Chang C.C., Jeng J.C., Hu H.M., Lin D.Y., Maul G.G., Kwok R.P., and Shih H.M. SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx. Proc. Natl. Acad. Sci. USA 102 (2005) 16973-16978
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 16973-16978
-
-
Kuo, H.Y.1
Chang, C.C.2
Jeng, J.C.3
Hu, H.M.4
Lin, D.Y.5
Maul, G.G.6
Kwok, R.P.7
Shih, H.M.8
-
118
-
-
0035799530
-
Functional analysis and intracellular localization of p53 modified by SUMO-1
-
Kwek S.S., Derry J., Tyner A.L., Shen Z., and Gudkov A.V. Functional analysis and intracellular localization of p53 modified by SUMO-1. Oncogene 20 (2001) 2587-2599
-
(2001)
Oncogene
, vol.20
, pp. 2587-2599
-
-
Kwek, S.S.1
Derry, J.2
Tyner, A.L.3
Shen, Z.4
Gudkov, A.V.5
-
119
-
-
0035908032
-
3-induced PML or PML/retinoic acid receptor α degradation
-
3-induced PML or PML/retinoic acid receptor α degradation. J. Exp. Med. 193 (2001) 1361-1371
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1361-1371
-
-
Lallemand-Breitenbach, V.1
Zhu, J.2
Puvion, F.3
Koken, M.4
Honore, N.5
Doubeikovsky, A.6
Duprez, E.7
Pandolfi, P.P.8
Puvion, E.9
Freemont, P.10
de The, H.11
-
120
-
-
43049096803
-
Arsenic degrades PML or PML-RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway
-
Lallemand-Breitenbach V., Jeanne M., Benhenda S., Nasr R., Lei M., Peres L., Zhou J., Zhu J., Raught B., and de The H. Arsenic degrades PML or PML-RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway. Nat. Cell Biol. 10 (2008) 547-555
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 547-555
-
-
Lallemand-Breitenbach, V.1
Jeanne, M.2
Benhenda, S.3
Nasr, R.4
Lei, M.5
Peres, L.6
Zhou, J.7
Zhu, J.8
Raught, B.9
de The, H.10
-
121
-
-
0036438977
-
Progesterone receptors-Animal models and cell signalling in breast cancer. Diverse activation pathways for the progesterone receptor: Possible implications for breast biology and cancer
-
Lanari C., and Molinolo A.A. Progesterone receptors-Animal models and cell signalling in breast cancer. Diverse activation pathways for the progesterone receptor: Possible implications for breast biology and cancer. Breast Cancer Res. 4 (2002) 240-243
-
(2002)
Breast Cancer Res.
, vol.4
, pp. 240-243
-
-
Lanari, C.1
Molinolo, A.A.2
-
122
-
-
0031104910
-
SMT3A, a human homologue of the S. cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family
-
Lapenta V., Chiurazzi P., van der Spek P., Pizzuti A., Hanaoka F., and Brahe C. SMT3A, a human homologue of the S. cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family. Genomics 40 (1997) 362-366
-
(1997)
Genomics
, vol.40
, pp. 362-366
-
-
Lapenta, V.1
Chiurazzi, P.2
van der Spek, P.3
Pizzuti, A.4
Hanaoka, F.5
Brahe, C.6
-
123
-
-
33646757232
-
The complexity of p53 stabilization and activation
-
Lavin M.F., and Gueven N. The complexity of p53 stabilization and activation. Cell Death Differ. 13 (2006) 941-950
-
(2006)
Cell Death Differ.
, vol.13
, pp. 941-950
-
-
Lavin, M.F.1
Gueven, N.2
-
124
-
-
0032512922
-
Modification of Ran GTPase-activating protein by the small ubiquitin-related modifier SUMO-1 requires Ubc9, an E2-type ubiquitin-conjugating enzyme homologue
-
Lee G.W., Melchior F., Matunis M.J., Mahajan R., Tian Q., and Anderson P. Modification of Ran GTPase-activating protein by the small ubiquitin-related modifier SUMO-1 requires Ubc9, an E2-type ubiquitin-conjugating enzyme homologue. J. Biol. Chem. 273 (1998) 6503-6507
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6503-6507
-
-
Lee, G.W.1
Melchior, F.2
Matunis, M.J.3
Mahajan, R.4
Tian, Q.5
Anderson, P.6
-
125
-
-
13544259457
-
The DEAD-box protein DP103 (Ddx20 or Gemin-3) represses orphan nuclear receptor activity via SUMO modification
-
Lee M.B., Lebedeva L.A., Suzawa M., Wadekar S.A., Desclozeaux M., and Ingraham H.A. The DEAD-box protein DP103 (Ddx20 or Gemin-3) represses orphan nuclear receptor activity via SUMO modification. Mol. Cell. Biol. 25 (2005) 1879-1890
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 1879-1890
-
-
Lee, M.B.1
Lebedeva, L.A.2
Suzawa, M.3
Wadekar, S.A.4
Desclozeaux, M.5
Ingraham, H.A.6
-
126
-
-
33751549096
-
SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination
-
Lee M.H., Lee S.W., Lee E.J., Choi S.J., Chung S.S., Lee J.I., Cho J.M., Seol J.H., Baek S.H., Kim K.I., Chiba T., Tanaka K., et al. SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination. Nat. Cell Biol. 8 (2006) 1424-1431
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1424-1431
-
-
Lee, M.H.1
Lee, S.W.2
Lee, E.J.3
Choi, S.J.4
Chung, S.S.5
Lee, J.I.6
Cho, J.M.7
Seol, J.H.8
Baek, S.H.9
Kim, K.I.10
Chiba, T.11
Tanaka, K.12
-
127
-
-
52649158231
-
Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex
-
Lee J., Lee Y., Lee M.J., Park E., Kang S.H., Chung C.H., Lee K.H., and Kim K. Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex. Mol. Cell. Biol 28 (2008) 6056-6065
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 6056-6065
-
-
Lee, J.1
Lee, Y.2
Lee, M.J.3
Park, E.4
Kang, S.H.5
Chung, C.H.6
Lee, K.H.7
Kim, K.8
-
128
-
-
35348847256
-
Transforming growth factor-β signaling in cancer invasion and metastasis
-
Leivonen S.K., and Kahari V.M. Transforming growth factor-β signaling in cancer invasion and metastasis. Int. J. Cancer 121 (2007) 2119-2124
-
(2007)
Int. J. Cancer
, vol.121
, pp. 2119-2124
-
-
Leivonen, S.K.1
Kahari, V.M.2
-
129
-
-
0033580444
-
A new protease required for cell-cycle progression in yeast
-
Li S.J., and Hochstrasser M. A new protease required for cell-cycle progression in yeast. Nature 398 (1999) 246-251
-
(1999)
Nature
, vol.398
, pp. 246-251
-
-
Li, S.J.1
Hochstrasser, M.2
-
130
-
-
0034018312
-
The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein
-
Li S.J., and Hochstrasser M. The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein. Mol. Cell. Biol. 20 (2000) 2367-2377
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 2367-2377
-
-
Li, S.J.1
Hochstrasser, M.2
-
131
-
-
33845989925
-
Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways
-
Li T., Santockyte R., Shen R.F., Tekle E., Wang G., Yang D.C., and Chock P.B. Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways. J. Biol. Chem. 281 (2006) 36221-36227
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 36221-36227
-
-
Li, T.1
Santockyte, R.2
Shen, R.F.3
Tekle, E.4
Wang, G.5
Yang, D.C.6
Chock, P.B.7
-
132
-
-
34447127473
-
Polycomb protein Cbx4 promotes SUMO modification of de novo DNA methyltransferase Dnmt3a
-
Li B., Zhou J., Liu P., Hu J., Jin H., Shimono Y., Takahashi M., and Xu G. Polycomb protein Cbx4 promotes SUMO modification of de novo DNA methyltransferase Dnmt3a. Biochem. J. 405 (2007) 369-378
-
(2007)
Biochem. J.
, vol.405
, pp. 369-378
-
-
Li, B.1
Zhou, J.2
Liu, P.3
Hu, J.4
Jin, H.5
Shimono, Y.6
Takahashi, M.7
Xu, G.8
-
133
-
-
40949111340
-
SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis
-
Li X., Luo Y., Yu L., Lin Y., Luo D., Zhang H., He Y., Kim Y.O., Kim Y., Tang S., and Min W. SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis. Cell Death Differ. 15 (2008) 739-750
-
(2008)
Cell Death Differ.
, vol.15
, pp. 739-750
-
-
Li, X.1
Luo, Y.2
Yu, L.3
Lin, Y.4
Luo, D.5
Zhang, H.6
He, Y.7
Kim, Y.O.8
Kim, Y.9
Tang, S.10
Min, W.11
-
134
-
-
57649138450
-
Structure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7
-
Lima C.D., and Reverter D. Structure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7. J. Biol. Chem. 283 (2008) 32045-32055
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 32045-32055
-
-
Lima, C.D.1
Reverter, D.2
-
135
-
-
34248141100
-
A cytokine-mediated link between innate immunity, inflammation, and cancer
-
Lin W.W., and Karin M. A cytokine-mediated link between innate immunity, inflammation, and cancer. J. Clin. Invest. 117 (2007) 1175-1183
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1175-1183
-
-
Lin, W.W.1
Karin, M.2
-
136
-
-
33746268330
-
KAI1/CD82, a tumor metastasis suppressor
-
Liu W.M., and Zhang X.A. KAI1/CD82, a tumor metastasis suppressor. Cancer Lett. 240 (2006) 183-194
-
(2006)
Cancer Lett.
, vol.240
, pp. 183-194
-
-
Liu, W.M.1
Zhang, X.A.2
-
137
-
-
0033546283
-
The binding interface between an E2 (UBC9) and a ubiquitin homologue (UBL1)
-
Liu Q., Jin C., Liao X., Shen Z., Chen D.J., and Chen Y. The binding interface between an E2 (UBC9) and a ubiquitin homologue (UBL1). J. Biol. Chem. 274 (1999) 16979-16987
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16979-16987
-
-
Liu, Q.1
Jin, C.2
Liao, X.3
Shen, Z.4
Chen, D.J.5
Chen, Y.6
-
138
-
-
4644367257
-
PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity
-
Liu B., Mink S., Wong K.A., Stein N., Getman C., Dempsey P.W., Wu H., and Shuai K. PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity. Nat. Immunol. 5 (2004) 891-898
-
(2004)
Nat. Immunol.
, vol.5
, pp. 891-898
-
-
Liu, B.1
Mink, S.2
Wong, K.A.3
Stein, N.4
Getman, C.5
Dempsey, P.W.6
Wu, H.7
Shuai, K.8
-
139
-
-
12844275070
-
Negative regulation of NF-κB signaling by PIAS1
-
Liu B., Yang R., Wong K.A., Getman C., Stein N., Teitell M.A., Cheng G., Wu H., and Shuai K. Negative regulation of NF-κB signaling by PIAS1. Mol. Cell. Biol. 25 (2005) 1113-1123
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 1113-1123
-
-
Liu, B.1
Yang, R.2
Wong, K.A.3
Getman, C.4
Stein, N.5
Teitell, M.A.6
Cheng, G.7
Wu, H.8
Shuai, K.9
-
140
-
-
34249039031
-
Proinflammatory stimuli induce IKKα-mediated phosphorylation of PIAS1 to restrict inflammation and immunity
-
Liu B., Yang Y., Chernishof V., Loo R.R., Jang H., Tahk S., Yang R., Mink S., Shultz D., Bellone C.J., Loo J.A., and Shuai K. Proinflammatory stimuli induce IKKα-mediated phosphorylation of PIAS1 to restrict inflammation and immunity. Cell 129 (2007) 903-914
-
(2007)
Cell
, vol.129
, pp. 903-914
-
-
Liu, B.1
Yang, Y.2
Chernishof, V.3
Loo, R.R.4
Jang, H.5
Tahk, S.6
Yang, R.7
Mink, S.8
Shultz, D.9
Bellone, C.J.10
Loo, J.A.11
Shuai, K.12
-
141
-
-
27444442397
-
Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin
-
Long J., Zuo D., and Park M. Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin. J. Biol. Chem. 280 (2005) 35477-35489
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35477-35489
-
-
Long, J.1
Zuo, D.2
Park, M.3
-
142
-
-
33751099563
-
Regulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteins
-
Lyst M.J., Nan X., and Stancheva I. Regulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteins. EMBO J. 25 (2006) 5317-5328
-
(2006)
EMBO J.
, vol.25
, pp. 5317-5328
-
-
Lyst, M.J.1
Nan, X.2
Stancheva, I.3
-
143
-
-
33748188499
-
PIASy mediates NEMO sumoylation and NF-κB activation in response to genotoxic stress
-
Mabb A.M., Wuerzberger-Davis S.M., and Miyamoto S. PIASy mediates NEMO sumoylation and NF-κB activation in response to genotoxic stress. Nat. Cell Biol. 8 (2006) 986-993
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 986-993
-
-
Mabb, A.M.1
Wuerzberger-Davis, S.M.2
Miyamoto, S.3
-
144
-
-
0030932134
-
A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2
-
Mahajan R., Delphin C., Guan T., Gerace L., and Melchior F. A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2. Cell 88 (1997) 97-107
-
(1997)
Cell
, vol.88
, pp. 97-107
-
-
Mahajan, R.1
Delphin, C.2
Guan, T.3
Gerace, L.4
Melchior, F.5
-
145
-
-
0029897809
-
Cloning and expression of human homolog HSMT3 to yeast SMT3 suppressor of MIF2 mutations in a centromere protein gene
-
Mannen H., Tseng H.M., Cho C.L., and Li S.S. Cloning and expression of human homolog HSMT3 to yeast SMT3 suppressor of MIF2 mutations in a centromere protein gene. Biochem. Biophys. Res. Commun. 222 (1996) 178-180
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.222
, pp. 178-180
-
-
Mannen, H.1
Tseng, H.M.2
Cho, C.L.3
Li, S.S.4
-
147
-
-
39049093685
-
In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy
-
Matic I., van Hagen M., Schimmel J., Macek B., Ogg S.C., Tatham M.H., Hay R.T., Lamond A.I., Mann M., and Vertegaal A.C. In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy. Mol. Cell Proteomics 7 (2008) 132-144
-
(2008)
Mol. Cell Proteomics
, vol.7
, pp. 132-144
-
-
Matic, I.1
van Hagen, M.2
Schimmel, J.3
Macek, B.4
Ogg, S.C.5
Tatham, M.H.6
Hay, R.T.7
Lamond, A.I.8
Mann, M.9
Vertegaal, A.C.10
-
148
-
-
0030455748
-
A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex
-
Matunis M.J., Coutavas E., and Blobel G. A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. J. Cell Biol. 135 (1996) 1457-1470
-
(1996)
J. Cell Biol.
, vol.135
, pp. 1457-1470
-
-
Matunis, M.J.1
Coutavas, E.2
Blobel, G.3
-
149
-
-
0032498541
-
SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex
-
Matunis M.J., Wu J., and Blobel G. SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex. J. Cell Biol. 140 (1998) 499-509
-
(1998)
J. Cell Biol.
, vol.140
, pp. 499-509
-
-
Matunis, M.J.1
Wu, J.2
Blobel, G.3
-
150
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell P.H., Wiesener M.S., Chang G.W., Clifford S.C., Vaux E.C., Cockman M.E., Wykoff C.C., Pugh C.W., Maher E.R., and Ratcliffe P.J. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399 (1999) 271-275
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
151
-
-
0029044625
-
Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C
-
Meluh P.B., and Koshland D. Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C. Mol. Biol. Cell 6 (1995) 793-807
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 793-807
-
-
Meluh, P.B.1
Koshland, D.2
-
152
-
-
34548848530
-
Small ubiquitin-related modifier (SUMO)-specific proteases: Profiling the specificities and activities of human SENPs
-
Mikolajczyk J., Drag M., Bekes M., Cao J.T., Ronai Z., and Salvesen G.S. Small ubiquitin-related modifier (SUMO)-specific proteases: Profiling the specificities and activities of human SENPs. J. Biol. Chem. 282 (2007) 26217-26224
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 26217-26224
-
-
Mikolajczyk, J.1
Drag, M.2
Bekes, M.3
Cao, J.T.4
Ronai, Z.5
Salvesen, G.S.6
-
153
-
-
16544390672
-
Overexpression of a dominant-negative mutant Ubc9 is associated with increased sensitivity to anticancer drugs
-
Mo Y.Y., Yu Y., Ee P.L., and Beck W.T. Overexpression of a dominant-negative mutant Ubc9 is associated with increased sensitivity to anticancer drugs. Cancer Res. 64 (2004) 2793-2798
-
(2004)
Cancer Res.
, vol.64
, pp. 2793-2798
-
-
Mo, Y.Y.1
Yu, Y.2
Ee, P.L.3
Beck, W.T.4
-
154
-
-
17844401262
-
A role for Ubc9 in tumorigenesis
-
Mo Y.Y., Yu Y., Theodosiou E., Rachel Ee P.L., and Beck W.T. A role for Ubc9 in tumorigenesis. Oncogene 24 (2005) 2677-2683
-
(2005)
Oncogene
, vol.24
, pp. 2677-2683
-
-
Mo, Y.Y.1
Yu, Y.2
Theodosiou, E.3
Rachel Ee, P.L.4
Beck, W.T.5
-
155
-
-
27644559050
-
TRAF7 sequesters c-Myb to the cytoplasm by stimulating its sumoylation
-
Morita Y., Kanei-Ishii C., Nomura T., and Ishii S. TRAF7 sequesters c-Myb to the cytoplasm by stimulating its sumoylation. Mol. Biol. Cell 16 (2005) 5433-5444
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 5433-5444
-
-
Morita, Y.1
Kanei-Ishii, C.2
Nomura, T.3
Ishii, S.4
-
156
-
-
33748990136
-
SUSP1 antagonizes formation of highly SUMO2/3-conjugated species
-
Mukhopadhyay D., Ayaydin F., Kolli N., Tan S.H., Anan T., Kametaka A., Azuma Y., Wilkinson K.D., and Dasso M. SUSP1 antagonizes formation of highly SUMO2/3-conjugated species. J. Cell Biol. 174 (2006) 939-949
-
(2006)
J. Cell Biol.
, vol.174
, pp. 939-949
-
-
Mukhopadhyay, D.1
Ayaydin, F.2
Kolli, N.3
Tan, S.H.4
Anan, T.5
Kametaka, A.6
Azuma, Y.7
Wilkinson, K.D.8
Dasso, M.9
-
157
-
-
0037498052
-
Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus
-
Muller S., Matunis M.J., and Dejean A. Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus. EMBO J. 17 (1998) 61-70
-
(1998)
EMBO J.
, vol.17
, pp. 61-70
-
-
Muller, S.1
Matunis, M.J.2
Dejean, A.3
-
158
-
-
0034607653
-
c-Jun and p53 activity is modulated by SUMO-1 modification
-
Muller S., Berger M., Lehembre F., Seeler J.S., Haupt Y., and Dejean A. c-Jun and p53 activity is modulated by SUMO-1 modification. J. Biol. Chem. 275 (2000) 13321-13329
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13321-13329
-
-
Muller, S.1
Berger, M.2
Lehembre, F.3
Seeler, J.S.4
Haupt, Y.5
Dejean, A.6
-
159
-
-
28444448039
-
The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice
-
Nacerddine K., Lehembre F., Bhaumik M., Artus J., Cohen-Tannoudji M., Babinet C., Pandolfi P.P., and Dejean A. The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice. Dev. Cell 9 (2005) 769-779
-
(2005)
Dev. Cell
, vol.9
, pp. 769-779
-
-
Nacerddine, K.1
Lehembre, F.2
Bhaumik, M.3
Artus, J.4
Cohen-Tannoudji, M.5
Babinet, C.6
Pandolfi, P.P.7
Dejean, A.8
-
160
-
-
0037163859
-
PIAS3 induces SUMO-1 modification and transcriptional repression of IRF-1
-
Nakagawa K., and Yokosawa H. PIAS3 induces SUMO-1 modification and transcriptional repression of IRF-1. FEBS Lett. 530 (2002) 204-208
-
(2002)
FEBS Lett.
, vol.530
, pp. 204-208
-
-
Nakagawa, K.1
Yokosawa, H.2
-
161
-
-
33646512458
-
SUMOylation attenuates sensitivity toward hypoxia- or desferroxamine-induced injury by modulating adaptive responses in salivary epithelial cells
-
Nguyen H.V., Chen J.L., Zhong J., Kim K.J., Crandall E.D., Borok Z., Chen Y., and Ann D.K. SUMOylation attenuates sensitivity toward hypoxia- or desferroxamine-induced injury by modulating adaptive responses in salivary epithelial cells. Am. J. Pathol. 168 (2006) 1452-1463
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 1452-1463
-
-
Nguyen, H.V.1
Chen, J.L.2
Zhong, J.3
Kim, K.J.4
Crandall, E.D.5
Borok, Z.6
Chen, Y.7
Ann, D.K.8
-
162
-
-
0036826887
-
PIAS1 and PIASxα function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription
-
Nishida T., and Yasuda H. PIAS1 and PIASxα function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription. J. Biol. Chem. 277 (2002) 41311-41317
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41311-41317
-
-
Nishida, T.1
Yasuda, H.2
-
163
-
-
0033760171
-
A novel mammalian Smt3-specific isopeptidase 1 (SMT3IP1) localized in the nucleolus at interphase
-
Nishida T., Tanaka H., and Yasuda H. A novel mammalian Smt3-specific isopeptidase 1 (SMT3IP1) localized in the nucleolus at interphase. Eur. J. Biochem. 267 (2000) 6423-6427
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 6423-6427
-
-
Nishida, T.1
Tanaka, H.2
Yasuda, H.3
-
164
-
-
3142716146
-
Transcriptional activity of peroxisome proliferator-activated receptor gamma is modulated by SUMO-1 modification
-
Ohshima T., Koga H., and Shimotohno K. Transcriptional activity of peroxisome proliferator-activated receptor gamma is modulated by SUMO-1 modification. J. Biol. Chem. 279 (2004) 29551-29557
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 29551-29557
-
-
Ohshima, T.1
Koga, H.2
Shimotohno, K.3
-
165
-
-
0033608252
-
In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2
-
Okuma T., Honda R., Ichikawa G., Tsumagari N., and Yasuda H. In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2. Biochem. Biophys. Res. Commun. 254 (1999) 693-698
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.254
, pp. 693-698
-
-
Okuma, T.1
Honda, R.2
Ichikawa, G.3
Tsumagari, N.4
Yasuda, H.5
-
166
-
-
0030588674
-
Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin
-
Okura T., Gong L., Kamitani T., Wada T., Okura I., Wei C.F., Chang H.M., and Yeh E.T. Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin. J. Immunol. 157 (1996) 4277-4281
-
(1996)
J. Immunol.
, vol.157
, pp. 4277-4281
-
-
Okura, T.1
Gong, L.2
Kamitani, T.3
Wada, T.4
Okura, I.5
Wei, C.F.6
Chang, H.M.7
Yeh, E.T.8
-
167
-
-
26444494924
-
A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation
-
Owerbach D., McKay E.M., Yeh E.T., Gabbay K.H., and Bohren K.M. A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation. Biochem. Biophys. Res. Commun. 337 (2005) 517-520
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.337
, pp. 517-520
-
-
Owerbach, D.1
McKay, E.M.2
Yeh, E.T.3
Gabbay, K.H.4
Bohren, K.M.5
-
168
-
-
4444238706
-
Expression of LUN gene that encodes a novel RING finger protein is correlated with development and progression of non-small cell lung cancer
-
Oyanagi H., Takenaka K., Ishikawa S., Kawano Y., Adachi Y., Ueda K., Wada H., and Tanaka F. Expression of LUN gene that encodes a novel RING finger protein is correlated with development and progression of non-small cell lung cancer. Lung Cancer 46 (2004) 21-28
-
(2004)
Lung Cancer
, vol.46
, pp. 21-28
-
-
Oyanagi, H.1
Takenaka, K.2
Ishikawa, S.3
Kawano, Y.4
Adachi, Y.5
Ueda, K.6
Wada, H.7
Tanaka, F.8
-
169
-
-
33845334175
-
Actions of TGF-β as tumor suppressor and pro-metastatic factor in human cancer
-
Pardali K., and Moustakas A. Actions of TGF-β as tumor suppressor and pro-metastatic factor in human cancer. Biochim. Biophys. Acta 1775 (2007) 21-62
-
(2007)
Biochim. Biophys. Acta
, vol.1775
, pp. 21-62
-
-
Pardali, K.1
Moustakas, A.2
-
170
-
-
26444471700
-
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ
-
Pascual G., Fong A.L., Ogawa S., Gamliel A., Li A.C., Perissi V., Rose D.W., Willson T.M., Rosenfeld M.G., and Glass C.K. A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ. Nature 437 (2005) 759-763
-
(2005)
Nature
, vol.437
, pp. 759-763
-
-
Pascual, G.1
Fong, A.L.2
Ogawa, S.3
Gamliel, A.4
Li, A.C.5
Perissi, V.6
Rose, D.W.7
Willson, T.M.8
Rosenfeld, M.G.9
Glass, C.K.10
-
171
-
-
0037059619
-
The nucleoporin RanBP2 has SUMO1 E3 ligase activity
-
Pichler A., Gast A., Seeler J.S., Dejean A., and Melchior F. The nucleoporin RanBP2 has SUMO1 E3 ligase activity. Cell 108 (2002) 109-120
-
(2002)
Cell
, vol.108
, pp. 109-120
-
-
Pichler, A.1
Gast, A.2
Seeler, J.S.3
Dejean, A.4
Melchior, F.5
-
172
-
-
17844401751
-
SUMO modification of the ubiquitin-conjugating enzyme E2-25K
-
Pichler A., Knipscheer P., Oberhofer E., van Dijk W.J., Korner R., Olsen J.V., Jentsch S., Melchior F., and Sixma T.K. SUMO modification of the ubiquitin-conjugating enzyme E2-25K. Nat. Struct. Mol. Biol. 12 (2005) 264-269
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 264-269
-
-
Pichler, A.1
Knipscheer, P.2
Oberhofer, E.3
van Dijk, W.J.4
Korner, R.5
Olsen, J.V.6
Jentsch, S.7
Melchior, F.8
Sixma, T.K.9
-
173
-
-
23344442009
-
Human MMS21/NSE2 is a SUMO ligase required for DNA repair
-
Potts P.R., and Yu H. Human MMS21/NSE2 is a SUMO ligase required for DNA repair. Mol. Cell. Biol. 25 (2005) 7021-7032
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 7021-7032
-
-
Potts, P.R.1
Yu, H.2
-
174
-
-
34447129654
-
The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins
-
Potts P.R., and Yu H. The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins. Nat. Struct. Mol. Biol. 14 (2007) 581-590
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 581-590
-
-
Potts, P.R.1
Yu, H.2
-
175
-
-
0034687807
-
Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1)
-
Poukka H., Karvonen U., Janne O.A., and Palvimo J.J. Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1). Proc. Natl. Acad. Sci. USA 97 (2000) 14145-14150
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 14145-14150
-
-
Poukka, H.1
Karvonen, U.2
Janne, O.A.3
Palvimo, J.J.4
-
176
-
-
34648840192
-
SUMO-targeted ubiquitin ligases in genome stability
-
Prudden J., Pebernard S., Raffa G., Slavin D.A., Perry J.J., Tainer J.A., McGowan C.H., and Boddy M.N. SUMO-targeted ubiquitin ligases in genome stability. EMBO J. 26 (2007) 4089-4101
-
(2007)
EMBO J.
, vol.26
, pp. 4089-4101
-
-
Prudden, J.1
Pebernard, S.2
Raffa, G.3
Slavin, D.A.4
Perry, J.J.5
Tainer, J.A.6
McGowan, C.H.7
Boddy, M.N.8
-
177
-
-
35648971684
-
TOPORS functions as a SUMO-1 E3 ligase for chromatin-modifying proteins
-
Pungaliya P., Kulkarni D., Park H.J., Marshall H., Zheng H., Lackland H., Saleem A., and Rubin E.H. TOPORS functions as a SUMO-1 E3 ligase for chromatin-modifying proteins. J. Proteome Res. 6 (2007) 3918-3923
-
(2007)
J. Proteome Res.
, vol.6
, pp. 3918-3923
-
-
Pungaliya, P.1
Kulkarni, D.2
Park, H.J.3
Marshall, H.4
Zheng, H.5
Lackland, H.6
Saleem, A.7
Rubin, E.H.8
-
178
-
-
4344563161
-
Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53
-
Rajendra R., Malegaonkar D., Pungaliya P., Marshall H., Rasheed Z., Brownell J., Liu L.F., Lutzker S., Saleem A., and Rubin E.H. Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53. J. Biol. Chem. 279 (2004) 36440-36444
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 36440-36444
-
-
Rajendra, R.1
Malegaonkar, D.2
Pungaliya, P.3
Marshall, H.4
Rasheed, Z.5
Brownell, J.6
Liu, L.F.7
Lutzker, S.8
Saleem, A.9
Rubin, E.H.10
-
179
-
-
0035969127
-
Role and fate of PML nuclear bodies in response to interferon and viral infections
-
Regad T., and Chelbi-Alix M.K. Role and fate of PML nuclear bodies in response to interferon and viral infections. Oncogene 20 (2001) 7274-7286
-
(2001)
Oncogene
, vol.20
, pp. 7274-7286
-
-
Regad, T.1
Chelbi-Alix, M.K.2
-
180
-
-
20444384040
-
Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex
-
Reverter D., and Lima C.D. Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex. Nature 435 (2005) 687-692
-
(2005)
Nature
, vol.435
, pp. 687-692
-
-
Reverter, D.1
Lima, C.D.2
-
181
-
-
33845370047
-
Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates
-
Reverter D., and Lima C.D. Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates. Nat. Struct. Mol. Biol. 13 (2006) 1060-1068
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 1060-1068
-
-
Reverter, D.1
Lima, C.D.2
-
182
-
-
0033571214
-
SUMO-1 modification activates the transcriptional response of p53
-
Rodriguez M.S., Desterro J.M., Lain S., Midgley C.A., Lane D.P., and Hay R.T. SUMO-1 modification activates the transcriptional response of p53. EMBO J. 18 (1999) 6455-6461
-
(1999)
EMBO J.
, vol.18
, pp. 6455-6461
-
-
Rodriguez, M.S.1
Desterro, J.M.2
Lain, S.3
Midgley, C.A.4
Lane, D.P.5
Hay, R.T.6
-
183
-
-
0035918226
-
SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting
-
Rodriguez M.S., Dargemont C., and Hay R.T. SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting. J. Biol. Chem. 276 (2001) 12654-12659
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12654-12659
-
-
Rodriguez, M.S.1
Dargemont, C.2
Hay, R.T.3
-
184
-
-
0041529514
-
SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation
-
Rogers R.S., Horvath C.M., and Matunis M.J. SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation. J. Biol. Chem. 278 (2003) 30091-30097
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 30091-30097
-
-
Rogers, R.S.1
Horvath, C.M.2
Matunis, M.J.3
-
185
-
-
33749058094
-
Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2
-
Roscic A., Moller A., Calzado M.A., Renner F., Wimmer V.C., Gresko E., Ludi K.S., and Schmitz M.L. Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2. Mol. Cell 24 (2006) 77-89
-
(2006)
Mol. Cell
, vol.24
, pp. 77-89
-
-
Roscic, A.1
Moller, A.2
Calzado, M.A.3
Renner, F.4
Wimmer, V.C.5
Gresko, E.6
Ludi, K.S.7
Schmitz, M.L.8
-
186
-
-
8444253635
-
PIASy-deficient mice display modest defects in IFN and Wnt signaling
-
Roth W., Sustmann C., Kieslinger M., Gilmozzi A., Irmer D., Kremmer E., Turck C., and Grosschedl R. PIASy-deficient mice display modest defects in IFN and Wnt signaling. J. Immunol. 173 (2004) 6189-6199
-
(2004)
J. Immunol.
, vol.173
, pp. 6189-6199
-
-
Roth, W.1
Sustmann, C.2
Kieslinger, M.3
Gilmozzi, A.4
Irmer, D.5
Kremmer, E.6
Turck, C.7
Grosschedl, R.8
-
187
-
-
41149144090
-
Identification of a new site of sumoylation on Tel (ETV6) uncovers a PIAS-dependent mode of regulating Tel function
-
Roukens M.G., loul-Ramdhani M., Vertegaal A.C., Anvarian Z., Balog C.I., Deelder A.M., Hensbergen P.J., and Baker D.A. Identification of a new site of sumoylation on Tel (ETV6) uncovers a PIAS-dependent mode of regulating Tel function. Mol. Cell. Biol. 28 (2008) 2342-2357
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 2342-2357
-
-
Roukens, M.G.1
loul-Ramdhani, M.2
Vertegaal, A.C.3
Anvarian, Z.4
Balog, C.I.5
Deelder, A.M.6
Hensbergen, P.J.7
Baker, D.A.8
-
188
-
-
0035576878
-
PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies
-
Sachdev S., Bruhn L., Sieber H., Pichler A., Melchior F., and Grosschedl R. PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies. Genes Dev. 15 (2001) 3088-3103
-
(2001)
Genes Dev.
, vol.15
, pp. 3088-3103
-
-
Sachdev, S.1
Bruhn, L.2
Sieber, H.3
Pichler, A.4
Melchior, F.5
Grosschedl, R.6
-
189
-
-
34648832906
-
Illuminating the metastatic process
-
Sahai E. Illuminating the metastatic process. Nat. Rev. Cancer 7 (2007) 737-749
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 737-749
-
-
Sahai, E.1
-
190
-
-
0034054669
-
Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3
-
Saitoh H., and Hinchey J. Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3. J. Biol. Chem. 275 (2000) 6252-6258
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6252-6258
-
-
Saitoh, H.1
Hinchey, J.2
-
191
-
-
0032518581
-
Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2
-
Saitoh H., Sparrow D.B., Shiomi T., Pu R.T., Nishimoto T., Mohun T.J., and Dasso M. Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2. Curr. Biol. 8 (1998) 121-124
-
(1998)
Curr. Biol.
, vol.8
, pp. 121-124
-
-
Saitoh, H.1
Sparrow, D.B.2
Shiomi, T.3
Pu, R.T.4
Nishimoto, T.5
Mohun, T.J.6
Dasso, M.7
-
192
-
-
3142754273
-
The topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressor
-
Saleem A., Dutta J., Malegaonkar D., Rasheed F., Rasheed Z., Rajendra R., Marshall H., Luo M., Li H., and Rubin E.H. The topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressor. Oncogene 23 (2004) 5293-5300
-
(2004)
Oncogene
, vol.23
, pp. 5293-5300
-
-
Saleem, A.1
Dutta, J.2
Malegaonkar, D.3
Rasheed, F.4
Rasheed, Z.5
Rajendra, R.6
Marshall, H.7
Luo, M.8
Li, H.9
Rubin, E.H.10
-
193
-
-
0141545024
-
Nup358 integrates nuclear envelope breakdown with kinetochore assembly
-
Salina D., Enarson P., Rattner J.B., and Burke B. Nup358 integrates nuclear envelope breakdown with kinetochore assembly. J. Cell Biol. 162 (2003) 991-1001
-
(2003)
J. Cell Biol.
, vol.162
, pp. 991-1001
-
-
Salina, D.1
Enarson, P.2
Rattner, J.B.3
Burke, B.4
-
194
-
-
0035877693
-
The small ubiquitin-like modifier-1 (SUMO-1) consensus sequence mediates Ubc9 binding and is essential for SUMO-1 modification
-
Sampson D.A., Wang M., and Matunis M.J. The small ubiquitin-like modifier-1 (SUMO-1) consensus sequence mediates Ubc9 binding and is essential for SUMO-1 modification. J. Biol. Chem. 276 (2001) 21664-21669
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21664-21669
-
-
Sampson, D.A.1
Wang, M.2
Matunis, M.J.3
-
195
-
-
0034767753
-
Antiviral actions of interferons
-
Table of contents
-
Samuel C.E. Antiviral actions of interferons. Clin. Microbiol. Rev. 14 (2001) 778-809 Table of contents
-
(2001)
Clin. Microbiol. Rev.
, vol.14
, pp. 778-809
-
-
Samuel, C.E.1
-
196
-
-
21344432585
-
Disruption of the murine PIASx gene results in reduced testis weight
-
Santti H., Mikkonen L., Anand A., Hirvonen-Santti S., Toppari J., Panhuysen M., Vauti F., Perera M., Corte G., Wurst W., Janne O.A., and Palvimo J.J. Disruption of the murine PIASx gene results in reduced testis weight. J. Mol. Endocrinol. 34 (2005) 645-654
-
(2005)
J. Mol. Endocrinol.
, vol.34
, pp. 645-654
-
-
Santti, H.1
Mikkonen, L.2
Anand, A.3
Hirvonen-Santti, S.4
Toppari, J.5
Panhuysen, M.6
Vauti, F.7
Perera, M.8
Corte, G.9
Wurst, W.10
Janne, O.A.11
Palvimo, J.J.12
-
197
-
-
57049091711
-
The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycle
-
Schimmel J., Larsen K.M., Matic I., van Hagen M., Cox J., Mann M., Andersen J.S., and Vertegaal A.C. The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycle. Mol. Cell Proteomics 7 (2008) 2107-2122
-
(2008)
Mol. Cell Proteomics
, vol.7
, pp. 2107-2122
-
-
Schimmel, J.1
Larsen, K.M.2
Matic, I.3
van Hagen, M.4
Cox, J.5
Mann, M.6
Andersen, J.S.7
Vertegaal, A.C.8
-
198
-
-
0037022564
-
Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity
-
Schmidt D., and Muller S. Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity. Proc. Natl. Acad. Sci. USA 99 (2002) 2872-2877
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2872-2877
-
-
Schmidt, D.1
Muller, S.2
-
199
-
-
0346100493
-
PIAS/SUMO: New partners in transcriptional regulation
-
Schmidt D., and Muller S. PIAS/SUMO: New partners in transcriptional regulation. Cell. Mol. Life Sci. 60 (2003) 2561-2574
-
(2003)
Cell. Mol. Life Sci.
, vol.60
, pp. 2561-2574
-
-
Schmidt, D.1
Muller, S.2
-
201
-
-
0031905771
-
The ubiquitin-like proteins SMT3 and SUMO-1 are conjugated by the UBC9 E2 enzyme
-
Schwarz S.E., Matuschewski K., Liakopoulos D., Scheffner M., and Jentsch S. The ubiquitin-like proteins SMT3 and SUMO-1 are conjugated by the UBC9 E2 enzyme. Proc. Natl. Acad. Sci. USA 95 (1998) 560-564
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 560-564
-
-
Schwarz, S.E.1
Matuschewski, K.2
Liakopoulos, D.3
Scheffner, M.4
Jentsch, S.5
-
202
-
-
27644467440
-
Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity
-
Sentis S., Le R.M., Bianchin C., Rostan M.C., and Corbo L. Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity. Mol. Endocrinol. 19 (2005) 2671-2684
-
(2005)
Mol. Endocrinol.
, vol.19
, pp. 2671-2684
-
-
Sentis, S.1
Le, R.M.2
Bianchin, C.3
Rostan, M.C.4
Corbo, L.5
-
203
-
-
0028967267
-
Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins
-
Seufert W., Futcher B., and Jentsch S. Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins. Nature 373 (1995) 78-81
-
(1995)
Nature
, vol.373
, pp. 78-81
-
-
Seufert, W.1
Futcher, B.2
Jentsch, S.3
-
204
-
-
0000531696
-
Arsenic trioxide as an inducer of apoptosis and loss of PML/RARα protein in acute promyelocytic leukemia cells
-
Shao W., Fanelli M., Ferrara F.F., Riccioni R., Rosenauer A., Davison K., Lamph W.W., Waxman S., Pelicci P.G., Lo C.F., Avvisati G., Testa U., et al. Arsenic trioxide as an inducer of apoptosis and loss of PML/RARα protein in acute promyelocytic leukemia cells. J. Natl. Cancer Inst. 90 (1998) 124-133
-
(1998)
J. Natl. Cancer Inst.
, vol.90
, pp. 124-133
-
-
Shao, W.1
Fanelli, M.2
Ferrara, F.F.3
Riccioni, R.4
Rosenauer, A.5
Davison, K.6
Lamph, W.W.7
Waxman, S.8
Pelicci, P.G.9
Lo, C.F.10
Avvisati, G.11
Testa, U.12
-
205
-
-
3042693287
-
Increase of SUMO-1 expression in response to hypoxia: Direct interaction with HIF-1α in adult mouse brain and heart in vivo
-
Shao R., Zhang F.P., Tian F., Anders F.P., Wang X., Sjoland H., and Billig H. Increase of SUMO-1 expression in response to hypoxia: Direct interaction with HIF-1α in adult mouse brain and heart in vivo. FEBS Lett. 569 (2004) 293-300
-
(2004)
FEBS Lett.
, vol.569
, pp. 293-300
-
-
Shao, R.1
Zhang, F.P.2
Tian, F.3
Anders, F.P.4
Wang, X.5
Sjoland, H.6
Billig, H.7
-
206
-
-
0030249870
-
UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins
-
Shen Z., Pardington-Purtymun P.E., Comeaux J.C., Moyzis R.K., and Chen D.J. UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins. Genomics 36 (1996) 271-279
-
(1996)
Genomics
, vol.36
, pp. 271-279
-
-
Shen, Z.1
Pardington-Purtymun, P.E.2
Comeaux, J.C.3
Moyzis, R.K.4
Chen, D.J.5
-
207
-
-
0242468041
-
Regulation of JAK-STAT signalling in the immune system
-
Shuai K., and Liu B. Regulation of JAK-STAT signalling in the immune system. Nat. Rev. Immunol. 3 (2003) 900-911
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 900-911
-
-
Shuai, K.1
Liu, B.2
-
208
-
-
23444461182
-
Regulation of gene-activation pathways by PIAS proteins in the immune system
-
Shuai K., and Liu B. Regulation of gene-activation pathways by PIAS proteins in the immune system. Nat. Rev. Immunol. 5 (2005) 593-605
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 593-605
-
-
Shuai, K.1
Liu, B.2
-
209
-
-
33845968538
-
Stress-induced inactivation of the c-Myb transcription factor through conjugation of SUMO-2/3 proteins
-
Sramko M., Markus J., Kabat J., Wolff L., and Bies J. Stress-induced inactivation of the c-Myb transcription factor through conjugation of SUMO-2/3 proteins. J. Biol. Chem. 281 (2006) 40065-40075
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 40065-40075
-
-
Sramko, M.1
Markus, J.2
Kabat, J.3
Wolff, L.4
Bies, J.5
-
210
-
-
34147208064
-
An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved ψKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity
-
Stankovic-Valentin N., Deltour S., Seeler J., Pinte S., Vergoten G., Guerardel C., Dejean A., and Leprince D. An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved ψKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity. Mol. Cell. Biol. 27 (2007) 2661-2675
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 2661-2675
-
-
Stankovic-Valentin, N.1
Deltour, S.2
Seeler, J.3
Pinte, S.4
Vergoten, G.5
Guerardel, C.6
Dejean, A.7
Leprince, D.8
-
211
-
-
0038100137
-
A synergy control motif within the attenuator domain of CCAAT/enhancer-binding protein alpha inhibits transcriptional synergy through its PIASy-enhanced modification by SUMO-1 or SUMO-3
-
Subramanian L., Benson M.D., and Iniguez-Lluhi J.A. A synergy control motif within the attenuator domain of CCAAT/enhancer-binding protein alpha inhibits transcriptional synergy through its PIASy-enhanced modification by SUMO-1 or SUMO-3. J. Biol. Chem. 278 (2003) 9134-9141
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9134-9141
-
-
Subramanian, L.1
Benson, M.D.2
Iniguez-Lluhi, J.A.3
-
212
-
-
34648816891
-
Conserved function of RNF4 family proteins in eukaryotes: Targeting a ubiquitin ligase to SUMOylated proteins
-
Sun H., Leverson J.D., and Hunter T. Conserved function of RNF4 family proteins in eukaryotes: Targeting a ubiquitin ligase to SUMOylated proteins. EMBO J. 26 (2007) 4102-4112
-
(2007)
EMBO J.
, vol.26
, pp. 4102-4112
-
-
Sun, H.1
Leverson, J.D.2
Hunter, T.3
-
213
-
-
0034712939
-
Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
-
Sutter C.H., Laughner E., and Semenza G.L. Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations. Proc. Natl. Acad. Sci. USA 97 (2000) 4748-4753
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4748-4753
-
-
Sutter, C.H.1
Laughner, E.2
Semenza, G.L.3
-
214
-
-
34547423214
-
Control of specificity and magnitude of NF-κB and STAT1-mediated gene activation through PIASy and PIAS1 cooperation
-
Tahk S., Liu B., Chernishof V., Wong K.A., Wu H., and Shuai K. Control of specificity and magnitude of NF-κB and STAT1-mediated gene activation through PIASy and PIAS1 cooperation. Proc. Natl. Acad. Sci. USA 104 (2007) 11643-11648
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 11643-11648
-
-
Tahk, S.1
Liu, B.2
Chernishof, V.3
Wong, K.A.4
Wu, H.5
Shuai, K.6
-
215
-
-
0035929557
-
Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9
-
Tatham M.H., Jaffray E., Vaughan O.A., Desterro J.M., Botting C.H., Naismith J.H., and Hay R.T. Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9. J. Biol. Chem. 276 (2001) 35368-35374
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35368-35374
-
-
Tatham, M.H.1
Jaffray, E.2
Vaughan, O.A.3
Desterro, J.M.4
Botting, C.H.5
Naismith, J.H.6
Hay, R.T.7
-
216
-
-
0037465706
-
Role of two residues proximal to the active site of Ubc9 in substrate recognition by the Ubc9.SUMO-1 thiolester complex
-
Tatham M.H., Chen Y., and Hay R.T. Role of two residues proximal to the active site of Ubc9 in substrate recognition by the Ubc9.SUMO-1 thiolester complex. Biochemistry 42 (2003) 3168-3179
-
(2003)
Biochemistry
, vol.42
, pp. 3168-3179
-
-
Tatham, M.H.1
Chen, Y.2
Hay, R.T.3
-
217
-
-
11444271001
-
Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection
-
Tatham M.H., Kim S., Jaffray E., Song J., Chen Y., and Hay R.T. Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection. Nat. Struct. Mol. Biol. 12 (2005) 67-74
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 67-74
-
-
Tatham, M.H.1
Kim, S.2
Jaffray, E.3
Song, J.4
Chen, Y.5
Hay, R.T.6
-
218
-
-
43049093756
-
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation
-
Tatham M.H., Geoffroy M.C., Shen L., Plechanovova A., Hattersley N., Jaffray E.G., Palvimo J.J., and Hay R.T. RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation. Nat. Cell Biol. 10 (2008) 538-546
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 538-546
-
-
Tatham, M.H.1
Geoffroy, M.C.2
Shen, L.3
Plechanovova, A.4
Hattersley, N.5
Jaffray, E.G.6
Palvimo, J.J.7
Hay, R.T.8
-
219
-
-
36849051990
-
The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation
-
Tsai Y.C., Mendoza A., Mariano J.M., Zhou M., Kostova Z., Chen B., Veenstra T., Hewitt S.M., Helman L.J., Khanna C., and Weissman A.M. The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation. Nat. Med. 13 (2007) 1504-1509
-
(2007)
Nat. Med.
, vol.13
, pp. 1504-1509
-
-
Tsai, Y.C.1
Mendoza, A.2
Mariano, J.M.3
Zhou, M.4
Kostova, Z.5
Chen, B.6
Veenstra, T.7
Hewitt, S.M.8
Helman, L.J.9
Khanna, C.10
Weissman, A.M.11
-
220
-
-
0033021104
-
Motility-related protein (MRP-1/CD9) and KAI1/CD82 expression inversely correlate with lymph node metastasis in oesophageal squamous cell carcinoma
-
Uchida S., Shimada Y., Watanabe G., Li Z.G., Hong T., Miyake M., and Imamura M. Motility-related protein (MRP-1/CD9) and KAI1/CD82 expression inversely correlate with lymph node metastasis in oesophageal squamous cell carcinoma. Br. J. Cancer 79 (1999) 1168-1173
-
(1999)
Br. J. Cancer
, vol.79
, pp. 1168-1173
-
-
Uchida, S.1
Shimada, Y.2
Watanabe, G.3
Li, Z.G.4
Hong, T.5
Miyake, M.6
Imamura, M.7
-
221
-
-
0142152429
-
PIAS proteins promote SUMO-1 conjugation to STAT1
-
Ungureanu D., Vanhatupa S., Kotaja N., Yang J., Aittomaki S., Janne O.A., Palvimo J.J., and Silvennoinen O. PIAS proteins promote SUMO-1 conjugation to STAT1. Blood 102 (2003) 3311-3313
-
(2003)
Blood
, vol.102
, pp. 3311-3313
-
-
Ungureanu, D.1
Vanhatupa, S.2
Kotaja, N.3
Yang, J.4
Aittomaki, S.5
Janne, O.A.6
Palvimo, J.J.7
Silvennoinen, O.8
-
222
-
-
36348977099
-
Ubiquitin-dependent proteolytic control of SUMO conjugates
-
Uzunova K., Gottsche K., Miteva M., Weisshaar S.R., Glanemann C., Schnellhardt M., Niessen M., Scheel H., Hofmann K., Johnson E.S., Praefcke G.J., and Dohmen R.J. Ubiquitin-dependent proteolytic control of SUMO conjugates. J. Biol. Chem. 282 (2007) 34167-34175
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 34167-34175
-
-
Uzunova, K.1
Gottsche, K.2
Miteva, M.3
Weisshaar, S.R.4
Glanemann, C.5
Schnellhardt, M.6
Niessen, M.7
Scheel, H.8
Hofmann, K.9
Johnson, E.S.10
Praefcke, G.J.11
Dohmen, R.J.12
-
223
-
-
33846019234
-
Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics
-
Vertegaal A.C., Andersen J.S., Ogg S.C., Hay R.T., Mann M., and Lamond A.I. Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics. Mol. Cell Proteomics 5 (2006) 2298-2310
-
(2006)
Mol. Cell Proteomics
, vol.5
, pp. 2298-2310
-
-
Vertegaal, A.C.1
Andersen, J.S.2
Ogg, S.C.3
Hay, R.T.4
Mann, M.5
Lamond, A.I.6
-
224
-
-
39649117348
-
SUMO4 and its role in type 1 diabetes pathogenesis
-
Wang C.Y., and She J.X. SUMO4 and its role in type 1 diabetes pathogenesis. Diabetes Metab. Res. Rev. 24 (2008) 93-102
-
(2008)
Diabetes Metab. Res. Rev.
, vol.24
, pp. 93-102
-
-
Wang, C.Y.1
She, J.X.2
-
225
-
-
33846636841
-
The role of SUMO in chromosome segregation
-
Watts F.Z. The role of SUMO in chromosome segregation. Chromosoma 116 (2007) 15-20
-
(2007)
Chromosoma
, vol.116
, pp. 15-20
-
-
Watts, F.Z.1
-
226
-
-
24144483441
-
Topors acts as a SUMO-1 E3 ligase for p53 in vitro and in vivo
-
Weger S., Hammer E., and Heilbronn R. Topors acts as a SUMO-1 E3 ligase for p53 in vitro and in vivo. FEBS Lett. 579 (2005) 5007-5012
-
(2005)
FEBS Lett.
, vol.579
, pp. 5007-5012
-
-
Weger, S.1
Hammer, E.2
Heilbronn, R.3
-
227
-
-
51249085621
-
Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML
-
Weisshaar S.R., Keusekotten K., Krause A., Horst C., Springer H.M., Gottsche K., Dohmen R.J., and Praefcke G.J. Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML. FEBS Lett. 582 (2008) 3174-3178
-
(2008)
FEBS Lett.
, vol.582
, pp. 3174-3178
-
-
Weisshaar, S.R.1
Keusekotten, K.2
Krause, A.3
Horst, C.4
Springer, H.M.5
Gottsche, K.6
Dohmen, R.J.7
Praefcke, G.J.8
-
228
-
-
23144449208
-
Ubiquitin and ubiquitin-like proteins as multifunctional signals
-
Welchman R.L., Gordon C., and Mayer R.J. Ubiquitin and ubiquitin-like proteins as multifunctional signals. Nat. Rev. Mol. Cell Biol. 6 (2005) 599-609
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 599-609
-
-
Welchman, R.L.1
Gordon, C.2
Mayer, R.J.3
-
230
-
-
2942557397
-
Protein inhibitor of activated STAT Y (PIASy) and a splice variant lacking exon 6 enhance sumoylation but are not essential for embryogenesis and adult life
-
Wong K.A., Kim R., Christofk H., Gao J., Lawson G., and Wu H. Protein inhibitor of activated STAT Y (PIASy) and a splice variant lacking exon 6 enhance sumoylation but are not essential for embryogenesis and adult life. Mol. Cell. Biol. 24 (2004) 5577-5586
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 5577-5586
-
-
Wong, K.A.1
Kim, R.2
Christofk, H.3
Gao, J.4
Lawson, G.5
Wu, H.6
-
232
-
-
33746806278
-
Coordinated regulation of AIB1 transcriptional activity by sumoylation and phosphorylation
-
Wu H., Sun L., Zhang Y., Chen Y., Shi B., Li R., Wang Y., Liang J., Fan D., Wu G., Wang D., Li S., et al. Coordinated regulation of AIB1 transcriptional activity by sumoylation and phosphorylation. J. Biol. Chem. 281 (2006) 21848-21856
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 21848-21856
-
-
Wu, H.1
Sun, L.2
Zhang, Y.3
Chen, Y.4
Shi, B.5
Li, R.6
Wang, Y.7
Liang, J.8
Fan, D.9
Wu, G.10
Wang, D.11
Li, S.12
-
233
-
-
33846783142
-
NF-κB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage
-
Wuerzberger-Davis S.M., Nakamura Y., Seufzer B.J., and Miyamoto S. NF-κB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage. Oncogene 26 (2007) 641-651
-
(2007)
Oncogene
, vol.26
, pp. 641-651
-
-
Wuerzberger-Davis, S.M.1
Nakamura, Y.2
Seufzer, B.J.3
Miyamoto, S.4
-
234
-
-
36348964395
-
The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation
-
Xie Y., Kerscher O., Kroetz M.B., McConchie H.F., Sung P., and Hochstrasser M. The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation. J. Biol. Chem. 282 (2007) 34176-34184
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 34176-34184
-
-
Xie, Y.1
Kerscher, O.2
Kroetz, M.B.3
McConchie, H.F.4
Sung, P.5
Hochstrasser, M.6
-
235
-
-
0037174133
-
P14ARF promotes accumulation of SUMO-1 conjugated (H)Mdm2
-
Xirodimas D.P., Chisholm J., Desterro J.M., Lane D.P., and Hay R.T. P14ARF promotes accumulation of SUMO-1 conjugated (H)Mdm2. FEBS Lett. 528 (2002) 207-211
-
(2002)
FEBS Lett.
, vol.528
, pp. 207-211
-
-
Xirodimas, D.P.1
Chisholm, J.2
Desterro, J.M.3
Lane, D.P.4
Hay, R.T.5
-
236
-
-
14844299866
-
Mapping residues of SUMO precursors essential in differential maturation by SUMO-specific protease, SENP1
-
Xu Z., and Au S.W. Mapping residues of SUMO precursors essential in differential maturation by SUMO-specific protease, SENP1. Biochem. J. 386 (2005) 325-330
-
(2005)
Biochem. J.
, vol.386
, pp. 325-330
-
-
Xu, Z.1
Au, S.W.2
-
237
-
-
20344379921
-
Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development
-
Yamaguchi T., Sharma P., Athanasiou M., Kumar A., Yamada S., and Kuehn M.R. Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development. Mol. Cell. Biol. 25 (2005) 5171-5182
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5171-5182
-
-
Yamaguchi, T.1
Sharma, P.2
Athanasiou, M.3
Kumar, A.4
Yamada, S.5
Kuehn, M.R.6
-
238
-
-
0033813529
-
KAI1 protein is down-regulated during the progression of human breast cancer
-
Yang X., Wei L., Tang C., Slack R., Montgomery E., and Lippman M. KAI1 protein is down-regulated during the progression of human breast cancer. Clin. Cancer Res. 6 (2000) 3424-3429
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3424-3429
-
-
Yang, X.1
Wei, L.2
Tang, C.3
Slack, R.4
Montgomery, E.5
Lippman, M.6
-
239
-
-
0041669469
-
Dynamic interplay of the SUMO and ERK pathways in regulating Elk-1 transcriptional activity
-
Yang S.H., Jaffray E., Hay R.T., and Sharrocks A.D. Dynamic interplay of the SUMO and ERK pathways in regulating Elk-1 transcriptional activity. Mol. Cell 12 (2003) 63-74
-
(2003)
Mol. Cell
, vol.12
, pp. 63-74
-
-
Yang, S.H.1
Jaffray, E.2
Hay, R.T.3
Sharrocks, A.D.4
-
240
-
-
52449102121
-
Repression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts
-
Yates K.E., Korbel G.A., Shtutman M., Roninson I.B., and Dimaio D. Repression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts. Aging Cell 7 (2008) 609-621
-
(2008)
Aging Cell
, vol.7
, pp. 609-621
-
-
Yates, K.E.1
Korbel, G.A.2
Shtutman, M.3
Roninson, I.B.4
Dimaio, D.5
-
241
-
-
0034595239
-
Ubiquitin-like proteins: New wines in new bottles
-
Yeh E.T., Gong L., and Kamitani T. Ubiquitin-like proteins: New wines in new bottles. Gene 248 (2000) 1-14
-
(2000)
Gene
, vol.248
, pp. 1-14
-
-
Yeh, E.T.1
Gong, L.2
Kamitani, T.3
-
242
-
-
0030878411
-
Loss of KAI1 messenger RNA expression in both high-grade and invasive human bladder cancers
-
Yu Y., Yang J.L., Markovic B., Jackson P., Yardley G., Barrett J., and Russell P.J. Loss of KAI1 messenger RNA expression in both high-grade and invasive human bladder cancers. Clin. Cancer Res. 3 (1997) 1045-1049
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 1045-1049
-
-
Yu, Y.1
Yang, J.L.2
Markovic, B.3
Jackson, P.4
Yardley, G.5
Barrett, J.6
Russell, P.J.7
-
243
-
-
0036724599
-
Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex
-
Zhang H., Saitoh H., and Matunis M.J. Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex. Mol. Cell. Biol. 22 (2002) 6498-6508
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6498-6508
-
-
Zhang, H.1
Saitoh, H.2
Matunis, M.J.3
-
244
-
-
50249096810
-
Sumo-1 function is dispensable in normal mouse development
-
Zhang F.P., Mikkonen L., Toppari J., Palvimo J.J., Thesleff I., and Janne O.A. Sumo-1 function is dispensable in normal mouse development. Mol. Cell. Biol. 28 (2008) 5381-5390
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 5381-5390
-
-
Zhang, F.P.1
Mikkonen, L.2
Toppari, J.3
Palvimo, J.J.4
Thesleff, I.5
Janne, O.A.6
-
245
-
-
40849115019
-
SUMO-2/3 modification and binding regulate the association of CENP-E with kinetochores and progression through mitosis
-
Zhang X.D., Goeres J., Zhang H., Yen T.J., Porter A.C., and Matunis M.J. SUMO-2/3 modification and binding regulate the association of CENP-E with kinetochores and progression through mitosis. Mol. Cell 29 (2008) 729-741
-
(2008)
Mol. Cell
, vol.29
, pp. 729-741
-
-
Zhang, X.D.1
Goeres, J.2
Zhang, H.3
Yen, T.J.4
Porter, A.C.5
Matunis, M.J.6
-
246
-
-
16344370926
-
A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization
-
Zhao X., and Blobel G. A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc. Natl. Acad. Sci. USA 102 (2005) 4777-4782
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4777-4782
-
-
Zhao, X.1
Blobel, G.2
-
247
-
-
25444462980
-
Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications
-
Zhao X., Sternsdorf T., Bolger T.A., Evans R.M., and Yao T.P. Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications. Mol. Cell. Biol. 25 (2005) 8456-8464
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 8456-8464
-
-
Zhao, X.1
Sternsdorf, T.2
Bolger, T.A.3
Evans, R.M.4
Yao, T.P.5
-
248
-
-
0030890942
-
Arsenic-induced PML targeting onto nuclear bodies: Implications for the treatment of acute promyelocytic leukemia
-
Zhu J., Koken M.H., Quignon F., Chelbi-Alix M.K., Degos L., Wang Z.Y., Chen Z., and de The H. Arsenic-induced PML targeting onto nuclear bodies: Implications for the treatment of acute promyelocytic leukemia. Proc. Natl. Acad. Sci. USA 94 (1997) 3978-3983
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3978-3983
-
-
Zhu, J.1
Koken, M.H.2
Quignon, F.3
Chelbi-Alix, M.K.4
Degos, L.5
Wang, Z.Y.6
Chen, Z.7
de The, H.8
-
249
-
-
34248225298
-
The SUMO protease SENP5 is required to maintain mitochondrial morphology and function
-
Zunino R., Schauss A., Rippstein P., Andrade-Navarro M., and McBride H.M. The SUMO protease SENP5 is required to maintain mitochondrial morphology and function. J. Cell Sci. 120 (2007) 1178-1188
-
(2007)
J. Cell Sci.
, vol.120
, pp. 1178-1188
-
-
Zunino, R.1
Schauss, A.2
Rippstein, P.3
Andrade-Navarro, M.4
McBride, H.M.5
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