Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation

Journal of Biological Chemistry

Volumn 277, Issue 49, 2002, Pages 47938-47945

  Bencsath, Kalman P ^a   Podgorski, Michael S ^a   Pagala, Vishwajeeth R ^a   Slaughter, Clive A ^a   Schulman, Brenda A ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; ESTERS; POLYMERS;

MULTIFUNCTIONAL BINDING SITES;

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE MAGNESIUM; ENZYME VARIANT; POLYMER; SUMO PROTEIN; THIOESTER; UBIQUITIN; UBIQUITIN LIKE PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CHEMICAL BOND; CONJUGATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE; SACCHAROMYCES CEREVISIAE; SURFACE PROPERTY;

BINDING SITES; CHROMATOGRAPHY, LIQUID; CLONING, MOLECULAR; DNA MUTATIONAL ANALYSIS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESTERS; LIGASES; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SULFHYDRYL COMPOUNDS; TIME FACTORS; UBIQUITIN-CONJUGATING ENZYMES;

SACCHAROMYCES CEREVISIAE;

EID: 0037033071     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207442200     Document Type: Article

References (59)

1. Hochstrasser, M. (2000) Nat. Cell Biol. 2, E153-E157
2. Glotzer, M., Murray, A. W., and Kirschner, M. W. (1991) Nature 349, 132-138
3. Pagano, M., Tam, S. W., Theodoras, A. M., Beer-Romero, P., Del Sal, G., Chau, V., Yew, P. R., Draetta, G. F., and Rolfe, M. (1995) Science 269, 682-685
4. Scheffner, M., Werness, B. A., Huibregtse, J. M., Levine, A. J., and Howley, P. M. (1990) Cell 63, 1129-1136
5. Aberle, H., Bauer, A., Stappert, J., Kispert, A., and Kemler, R. (1997) EMBO J. 16, 3797-3804
6. Salceda, S., and Caro, J. (1997) J. Biol. Chem. 272, 22642-22647
7. Pickart, C. M. (2001) Annu. Rev. Biochem. 70, 503-533
8. Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., You, J., Slaughter, C., Pickart, C., and Chen, Z. J. (2000) Cell 103, 351-361
9. Hicke, L. (2001) Nat. Rev. Mol. Cell. Biol. 2, 195-201
10. Lammer, D., Mathias, N., Laplaza, J. M., Jiang, W., Liu, Y., Callis, J., Goebl, M., and Estelle, M. (1998) Genes Dev. 12, 914-926
11. Liakopoulos, D., Doenges, G., Matuschewski, K., and Jentsch, S. (1998) EMBO J. 17, 2208-2214
12. Tateishi, K., Omata, M., Tanaka, K., and Chiba, T. (2001) J. Cell Biol. 155, 571-579
13. Ichimura, Y., Kirisako, T., Takao, T., Satomi, Y., Shimonishi, Y., Ishihara, N., Mizushima, N., Tanida, I., Kominami, E., Ohsumi, M., Noda, T., and Ohsumi, Y. (2000) Nature 408, 488-492
14. Hay, R. T. (2001) Trends Biochem. Sci. 26, 332-333
15. Muller, S., Hoege, C., Pyrowolakis, G., and Jentsch, S. (2001) Nat. Rev. Mol. Cell. Biol. 2, 202-210
16. Takahashi, Y., Kahyo, T., Toh, E. A., Yasuda, H., and Kikuchi, Y. (2001) J. Biol. Chem. 27, 27
17. Johnson, E. S., and Gupta, A. A. (2001) Cell 106, 735-744
18. Tatham, M. H., Jaffray, E., Vaughan, O. A., Desterro, J. M., Botting, C. H., Naismith, J. H., and Hay, R. T. (2001) J. Biol. Chem. 276, 35368-35374
19. Pichler, A., Gast, A., Seeler, J. S., Dejean, A., and Melchior, F. (2002) Cell 108, 109-120
20. Schmidt, D., and Muller, S. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 2872-2877
21. Johnson, E. S., Schwienhorst, I., Dohmen, R. J., and Blobel, G. (1997) EMBO J. 16, 5509-5519
22. Johnson, E. S., and Blobel, G. (1997) J. Biol. Chem. 272, 26799-26802
23. Hochstrasser, M. (1998) Genes Dev. 12, 901-907
24. Gong, L., Li, B., Millas, S., and Yeh, E. T. (1999) FEBS Lett. 448, 185-189
25. Gong, L., and Yeh, E. T. (1999) J. Biol. Chem. 274, 12036-12042
26. Desterro, J. M., Rodriguez, M. S., Kemp, G. D., and Hay, R. T. (1999) J. Biol. Chem. 274, 10618-10624
27. Kahyo, T., Nishida, T., and Yasuda, H. (2001) Mol. Cell 8, 713-718
28. Joazeiro, C. A., and Weissman, A. M. (2000) Cell 102, 549-552
29. Gosink, M. M., and Vierstra, R. D. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 9117-9121
30. Melchior, F. (2000) Annu. Rev. Cell Dev. Biol. 16, 591-626
31. Jentsch, S., McGrath, J. P., and Varshavsky, A. (1987) Nature 329, 131-134
32. Goebl, M. G., Yochem, J., Jentsch, S., McGrath, J. P., Varshavsky, A., and Byers, B. (1988) Science 241, 1331-1335
33. Seufert, W., Futcher, B., and Jentsch, S. (1995) Nature 373, 78-81
34. Schwarz, S. E., Matuschewski, K., Liakopoulos, D., Scheffner, M., and Jentsch, S. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 560-564
35. Huang, L., Kinnucan, E., Wang, G., Beaudenon, S., Howley, P. M., Huibregtse, J. M., and Pavletich, N. P. (1999) Science 286, 1321-1326
36. Zheng, N., Wang, P., Jeffrey, P. D., and Pavletich, N. P. (2000) Cell 102, 533-539
37. Miura, T., Klaus, W., Gsell, B., Miyamoto, C., and Senn, H. (1999) J. Mol. Biol. 290, 213-228
38. Liu, Q., Jin, C., Liao, X., Shen, Z., Chen, D. J., and Chen, Y. (1999) J. Biol. Chem. 274, 16979-16987
39. Hamilton, K. S., Ellison, M. J., Barber, K. R., Williams, R. S., Huzil, J. T., McKenna, S., Ptak, C., Glover, M., and Shaw, G. S. (2001) Structure 9, 897-904
40. Bernier-Villamor, V., Sampson, D. A., Matunis, M. J., and Lima, C. D. (2002) Cell 108, 345-356
41. Haas, A. L., Bright, P. M., and Jackson, V. E. (1988) J. Biol. Chem. 263, 13268-13275
42. Schulman, B. A., Carrano, A. C., Jeffrey, P. D., Bowen, Z., Kinnucan, E. R., Finnin, M. S., Elledge, S. J., Harper, J. W., Pagano, M., and Pavletich, N. P. (2000) Nature 408, 381-386
43. Tong, H., Hateboer, G., Perrakis, A., Bernards, R., and Sixma, T. K. (1997) J. Biol. Chem. 272, 21381-21387
44. Giraud, M. F., Desterro, J. M., and Naismith, J. H. (1998) Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 891-898
45. McKenna, S., Spyracopoulos, L., Moraes, T., Pastushok, L., Ptak, C., Xiao, W., and Ellison, M. J. (2001) J. Biol. Chem. 276, 40120-40126
46. Lin, Y., Hwang, W. C., and Basavappa, R. (2002) J. Biol. Chem. 277, 21913-21921
47. Gong, L., Kamitani, T., Fujise, K., Caskey, L. S., and Yeh, E. T. (1997) J. Biol. Chem. 272, 28198-28201
48. Uetz, P., Giot, L., Cagney, G., Mansfield, T. A., Judson, R. S., Knight, J. R., Lockshon, D., Narayan, V., Srinivasan, M., Pochart, P., Qureshi-Emili, A., Li, Y., Godwin, B., Conover, D., Kalbfleisch, T., Vijayadamodar, G., Yang, M., Johnston, M., Fields, S., and Rothberg, J. M. (2000) Nature 403, 623-627
49. Ito, T., Chiba, T., Ozawa, R., Yoshida, M., Hattori, M., and Sakaki, Y. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 4569-4574
50. Ciechanover, A., Elias, S., Heller, H., and Hershko, A. (1982) J. Biol. Chem. 257, 2537-2542
51. Haas, A. L., and Rose, I. A. (1982) J. Biol. Chem. 257, 10329-10337
52. Sampson, D. A., Wang, M., and Matunis, M. J. (2001) J. Biol. Chem. 276, 21664-21669
53. VanDemark, A. P., Hofmann, R. M., Tsui, C., Pickart, C. M., and Wolberger, C. (2001) Cell 105, 711-720
54. Whitby, F. G., Xia, G., Pickart, C. M., and Hill, C. P. (1998) J. Biol. Chem. 273, 34983-34991
55. Sullivan, M. L., and Vierstra, R. D. (1991) J. Biol. Chem. 266, 23878-23885
56. Pitluk, Z. W., McDonough, M., Sangan, P., and Gonda, D. K. (1995) Mol. Cell. Biol. 15, 1210-1219
57. Cook, W. J., Jeffrey, L. C., Sullivan, M. L., and Vierstra, R. D. (1992) J. Biol. Chem. 267, 15116-15121
58. Moraes, T. F., Edwards, R. A., McKenna, S., Pastushok, L., Xiao, W., Glover, J. N., and Ellison, M. J. (2001) Nat. Struct. Biol. 8, 669-673
59. Pornillos, O., Alam, S. L., Rich, R. L., Myszka, D. G., Davis, D. R., and Sundquist, W. I. (2002) EMBO J. 21, 2397-2406