-
1
-
-
0037677203
-
PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4
-
Arora, T., B. Liu, H. He, J. Kim, T. L. Murphy, K. M. Murphy, R. L. Modlin, and K. Shuai. 2003. PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4. J. Biol. Chem. 278:21327-21330.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21327-21330
-
-
Arora, T.1
Liu, B.2
He, H.3
Kim, J.4
Murphy, T.L.5
Murphy, K.M.6
Modlin, R.L.7
Shuai, K.8
-
2
-
-
0030747128
-
NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules
-
Baeuerle, P. A., and V. R. Baichwal. 1997. NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules. Adv. Immunol. 65:111-137.
-
(1997)
Adv. Immunol.
, vol.65
, pp. 111-137
-
-
Baeuerle, P.A.1
Baichwal, V.R.2
-
3
-
-
0031080138
-
NF-kappa B: A pivotal role in asthma and a new target for therapy
-
Barnes, P. J., and I. M. Adcock. 1997. NF-kappa B: a pivotal role in asthma and a new target for therapy. Trends Pharmacol. Sci. 18:46-50.
-
(1997)
Trends Pharmacol. Sci.
, vol.18
, pp. 46-50
-
-
Barnes, P.J.1
Adcock, I.M.2
-
4
-
-
0030615201
-
Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes, P. J., and M. Karin. 1997. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336:1066-1071.
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
5
-
-
0028971291
-
Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice
-
Beg, A. A., W. C. Sha, R. T. Bronson, and D. Baltimore. 1995. Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice. Genes Dev. 9:2736-2746.
-
(1995)
Genes Dev.
, vol.9
, pp. 2736-2746
-
-
Beg, A.A.1
Sha, W.C.2
Bronson, R.T.3
Baltimore, D.4
-
6
-
-
0032577678
-
Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
-
Chen, X., U. Vinkemeier, Y. Zhao, D. Jeruzalmi, J. E. Darnell, Jr., and J. Kuriyan. 1998. Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell 93:827-839.
-
(1998)
Cell
, vol.93
, pp. 827-839
-
-
Chen, X.1
Vinkemeier, U.2
Zhao, Y.3
Jeruzalmi, D.4
Darnell Jr., J.E.5
Kuriyan, J.6
-
7
-
-
0037075549
-
Involvement of receptor-interacting protein 2 in innate and adaptive immune responses
-
Chin, A. I., P. W. Dempsey, K. Bruhn, J. F. Miller, Y. Xu, and G. Cheng. 2002. Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature 416:190-194.
-
(2002)
Nature
, vol.416
, pp. 190-194
-
-
Chin, A.I.1
Dempsey, P.W.2
Bruhn, K.3
Miller, J.F.4
Xu, Y.5
Cheng, G.6
-
8
-
-
0030725378
-
Specific inhibition of Stat3 signal transduction by PIAS3
-
Chung, C. D., J. Liao, B. Liu, X. Rao, P. Jay, P. Berta, and K. Shuai. 1997. Specific inhibition of Stat3 signal transduction by PIAS3. Science 278:1803-1805.
-
(1997)
Science
, vol.278
, pp. 1803-1805
-
-
Chung, C.D.1
Liao, J.2
Liu, B.3
Rao, X.4
Jay, P.5
Berta, P.6
Shuai, K.7
-
9
-
-
18644376284
-
IRF3 mediates a TLR3/TLR4-specific antiviral gene program
-
Doyle, S., S. Vaidya, R. O'Connell, H. Dadgostar, P. Dempsey, T. Wu, G. Rao, R. Sun, M. Haberland, R. Modlin, and G. Cheng. 2002. IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity 17:251-263.
-
(2002)
Immunity
, vol.17
, pp. 251-263
-
-
Doyle, S.1
Vaidya, S.2
O'Connell, R.3
Dadgostar, H.4
Dempsey, P.5
Wu, T.6
Rao, G.7
Sun, R.8
Haberland, M.9
Modlin, R.10
Cheng, G.11
-
10
-
-
0032493278
-
Efficient adenoviral infection with IkappaB alpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent
-
Foxwell, B., K. Browne, J. Bondeson, C. Clarke, R. de Martin, F. Brennan, and M. Feldmann. 1998. Efficient adenoviral infection with IkappaB alpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent. Proc. Natl. Acad. Sci. USA 95:8211-8215.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8211-8215
-
-
Foxwell, B.1
Browne, K.2
Bondeson, J.3
Clarke, C.4
De Martin, R.5
Brennan, F.6
Feldmann, M.7
-
11
-
-
0036234459
-
Missing pieces in the NF-kappaB puzzle
-
Ghosh, S., and M. Karin. 2002. Missing pieces in the NF-kappaB puzzle. Cell 109(Suppl.):S81-S96.
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Ghosh, S.1
Karin, M.2
-
12
-
-
0029662342
-
Rel/NF-kappaB/IkappaB proteins and cancer
-
Gilmore, T. D., M. Koedood, K. A. Piffat, and D. W. White. 1996. Rel/NF-kappaB/IkappaB proteins and cancer. Oncogene 13:1367-1378.
-
(1996)
Oncogene
, vol.13
, pp. 1367-1378
-
-
Gilmore, T.D.1
Koedood, M.2
Piffat, K.A.3
White, D.W.4
-
13
-
-
0035963311
-
Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells
-
Gross, M., B. Liu, J. Tan, F. S. French, M. Carey, and K. Shuai. 2001. Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells. Oncogene 20:3880-3887.
-
(2001)
Oncogene
, vol.20
, pp. 3880-3887
-
-
Gross, M.1
Liu, B.2
Tan, J.3
French, F.S.4
Carey, M.5
Shuai, K.6
-
14
-
-
2642520591
-
PIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunit
-
Jang, H. D., K. Yoon, Y. J. Shin, J. Kim, and S. Y. Lee. 2004. PIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunit. J. Biol. Chem. 279:24873-24880.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24873-24880
-
-
Jang, H.D.1
Yoon, K.2
Shin, Y.J.3
Kim, J.4
Lee, S.Y.5
-
15
-
-
0034789730
-
Involvement of PIAS1 in the sumoylation of tumor suppressor p53
-
Kahyo, T., T. Nishida, and H. Yasuda. 2001. Involvement of PIAS1 in the sumoylation of tumor suppressor p53. Mol. Cell 8:713-718.
-
(2001)
Mol. Cell
, vol.8
, pp. 713-718
-
-
Kahyo, T.1
Nishida, T.2
Yasuda, H.3
-
16
-
-
0033595893
-
How NF-kappaB is activated: The role of the IkappaB kinase (IKK) complex
-
Karin, M. 1999. How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex. Oncogene 18:6867-6874.
-
(1999)
Oncogene
, vol.18
, pp. 6867-6874
-
-
Karin, M.1
-
17
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-ΚB activity
-
Karin, M., and Y. Ben-Neriah. 2000. Phosphorylation meets ubiquitination: the control of NF-ΚB activity. Annu. Rev. Immunol. 18:621-663.
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
18
-
-
0036009115
-
NF-kappaB at the crossroads of life and death
-
Karin, M., and A. Lin. 2002. NF-kappaB at the crossroads of life and death. Nat. Immunol. 3:221-227.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
19
-
-
0035020493
-
Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome
-
Le, L. Q., J. H. Kabarowski, Z. Weng, A. B. Satterthwaite, E. T. Harvill, E. R. Jensen, J. F. Miller, and O. N. Witte. 2001. Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome. Immunity 14:561-571.
-
(2001)
Immunity
, vol.14
, pp. 561-571
-
-
Le, L.Q.1
Kabarowski, J.H.2
Weng, Z.3
Satterthwaite, A.B.4
Harvill, E.T.5
Jensen, E.R.6
Miller, J.F.7
Witte, O.N.8
-
20
-
-
0033529416
-
NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes
-
Lee, H. H., H. Dadgostar, Q. Cheng, J. Shu, and G. Cheng. 1999. NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes. Proc. Natl. Acad. Sci. USA 96:9136-9141.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9136-9141
-
-
Lee, H.H.1
Dadgostar, H.2
Cheng, Q.3
Shu, J.4
Cheng, G.5
-
21
-
-
0035853098
-
A transcriptional corepressor of Stat1 with an essential LXXLL signature motif
-
Liu, B., M. Gross, J. ten Hoeve, and K. Shuai. 2001. A transcriptional corepressor of Stat1 with an essential LXXLL signature motif. Proc. Natl. Acad. Sci. USA 98:3203-3207.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3203-3207
-
-
Liu, B.1
Gross, M.2
Ten Hoeve, J.3
Shuai, K.4
-
22
-
-
0032169599
-
Inhibition of Stat1-mediated gene activation by PIAS1
-
Liu, B., J. Liao, X. Rao, S. A. Kushner, C. D. Chung, D. D. Chang, and K. Shuai. 1998. Inhibition of Stat1-mediated gene activation by PIAS1. Proc. Natl. Acad. Sci. USA 95:10626-10631.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 10626-10631
-
-
Liu, B.1
Liao, J.2
Rao, X.3
Kushner, S.A.4
Chung, C.D.5
Chang, D.D.6
Shuai, K.7
-
23
-
-
4644367257
-
PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity
-
Liu, B., S. Mink, K. A. Wong, N. Stein, C. Getman, P. W. Dempsey, H. Wu, and K. Shuai. 2004. PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity. Nat. Immunol. 5:891-898.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 891-898
-
-
Liu, B.1
Mink, S.2
Wong, K.A.3
Stein, N.4
Getman, C.5
Dempsey, P.W.6
Wu, H.7
Shuai, K.8
-
24
-
-
0035965227
-
Induction of apoptosis by protein inhibitor of activated Stat1 through c-Jun NH2-terminal kinase activation
-
Liu, B., and K. Shuai. 2001. Induction of apoptosis by protein inhibitor of activated Stat1 through c-Jun NH2-terminal kinase activation. J. Biol. Chem. 276:36624-36631.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 36624-36631
-
-
Liu, B.1
Shuai, K.2
-
25
-
-
0034704180
-
An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity
-
Majeti, R., Z. Xu, T. G. Parslow, J. L. Olson, D. I. Daikh, N. Killeen, and A. Weiss. 2000. An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity. Cell 103:1059-1070.
-
(2000)
Cell
, vol.103
, pp. 1059-1070
-
-
Majeti, R.1
Xu, Z.2
Parslow, T.G.3
Olson, J.L.4
Daikh, D.I.5
Killeen, N.6
Weiss, A.7
-
26
-
-
0037041024
-
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
-
Megidish, T., J. H. Xu, and C. W. Xu. 2002. Activation of p53 by protein inhibitor of activated Stat1 (PIAS1). J. Biol. Chem. 277:8255-8259.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8255-8259
-
-
Megidish, T.1
Xu, J.H.2
Xu, C.W.3
-
27
-
-
0033216629
-
NF-kappaB as a primary regulator of the stress response
-
Mercurio, F., and A. M. Manning. 1999. NF-kappaB as a primary regulator of the stress response. Oncogene 18:6163-6171.
-
(1999)
Oncogene
, vol.18
, pp. 6163-6171
-
-
Mercurio, F.1
Manning, A.M.2
-
28
-
-
0033525191
-
A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins
-
Moilanen, A. M., U. Karvonen, H. Poukka, W. Van, J. Toppari, O. A. Jeanne, and J. J. Palvimo. 1999. A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins. J. Biol. Chem. 274:3700-3704.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 3700-3704
-
-
Moilanen, A.M.1
Karvonen, U.2
Poukka, H.3
Van, W.4
Toppari, J.5
Jeanne, O.A.6
Palvimo, J.J.7
-
29
-
-
0030790967
-
Induction of IP-10 chemokine promoter by measles virus: Comparison with interferon-gamma shows the use of the same response element but with differential DNA-protein binding profiles
-
Nazar, A. S., G. Cheng, H. S. Shin, P. N. Brothers, S. Dhib-Jalbut, M. L. Shin, and P. Vanguri. 1997. Induction of IP-10 chemokine promoter by measles virus: comparison with interferon-gamma shows the use of the same response element but with differential DNA-protein binding profiles. J. Neuroimmunol. 77:116-127.
-
(1997)
J. Neuroimmunol.
, vol.77
, pp. 116-127
-
-
Nazar, A.S.1
Cheng, G.2
Shin, H.S.3
Brothers, P.N.4
Dhib-Jalbut, S.5
Shin, M.L.6
Vanguri, P.7
-
30
-
-
0030608917
-
Convergence of TNFalpha and IFNgamma signalling pathways through synergistic induction of IRF-1/ISGF-2 is mediated by a composite GAS/kappaB promoter element
-
Pine, R. 1997. Convergence of TNFalpha and IFNgamma signalling pathways through synergistic induction of IRF-1/ISGF-2 is mediated by a composite GAS/kappaB promoter element. Nucleic Acids Res. 25:4346-4354.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 4346-4354
-
-
Pine, R.1
-
31
-
-
0035576878
-
PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies
-
Sachdev, S., L. Bruhn, H. Sieber, A. Pichler, F. Melchior, and R. Grosschedl. 2001. PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies. Genes Dev. 15:3088-3103.
-
(2001)
Genes Dev.
, vol.15
, pp. 3088-3103
-
-
Sachdev, S.1
Bruhn, L.2
Sieber, H.3
Pichler, A.4
Melchior, F.5
Grosschedl, R.6
-
32
-
-
0037022564
-
Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity
-
Schmidt, D., and S. Muller. 2002. Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity. Proc. Natl. Acad. Sci. USA 99:2872-2877.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2872-2877
-
-
Schmidt, D.1
Muller, S.2
-
33
-
-
0242468041
-
Regulation of JAK-STAT signalling in the immune system
-
Shuai, K., and B. Liu. 2003. Regulation of JAK-STAT signalling in the immune system. Nat. Rev. Immunol. 3:900-911.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 900-911
-
-
Shuai, K.1
Liu, B.2
-
34
-
-
0027493650
-
A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma
-
Shuai, K., G. R. Stark, I. M. Kerr, and J. E. Darnell, Jr. 1993. A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma. Science 261:1744-1746.
-
(1993)
Science
, vol.261
, pp. 1744-1746
-
-
Shuai, K.1
Stark, G.R.2
Kerr, I.M.3
Darnell Jr., J.E.4
-
35
-
-
0037462477
-
Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity
-
Sosic, D., J. A. Richardson, K. Yu, D. M. Ornitz, and E. N. Olson. 2003. Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity. Cell 112:169-180.
-
(2003)
Cell
, vol.112
, pp. 169-180
-
-
Sosic, D.1
Richardson, J.A.2
Yu, K.3
Ornitz, D.M.4
Olson, E.N.5
-
36
-
-
0034453206
-
Protein inhibitor of activated Stat-1 is a nuclear receptor co-regulator expressed in human testis
-
Tan, J., S. H. Hall, K. G. Hamil, G. Grossman, P. Petrusz, J. Liao, K. Shuai, and F. S. French. 2000. Protein inhibitor of activated Stat-1 is a nuclear receptor co-regulator expressed in human testis. Mol. Endocrinol. 14:14-26.
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 14-26
-
-
Tan, J.1
Hall, S.H.2
Hamil, K.G.3
Grossman, G.4
Petrusz, P.5
Liao, J.6
Shuai, K.7
French, F.S.8
-
37
-
-
0037053440
-
Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor coregulators
-
Tan, J. A., S. H. Hall, K. G. Hamil, G. Grossman, P. Petrusz, and F. S. French. 2002. Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor coregulators. J. Biol. Chem. 277:16993-17001.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 16993-17001
-
-
Tan, J.A.1
Hall, S.H.2
Hamil, K.G.3
Grossman, G.4
Petrusz, P.5
French, F.S.6
-
38
-
-
0037417136
-
Identification of NF-kappa B-regulated genes induced by TNFalpha utilizing expression profiling and RNA interference
-
Zhou, A., S. Scoggin, R. B. Gaynor, and N. S. Williams. 2003. Identification of NF-kappa B-regulated genes induced by TNFalpha utilizing expression profiling and RNA interference. Oncogene 22:2054-2064.
-
(2003)
Oncogene
, vol.22
, pp. 2054-2064
-
-
Zhou, A.1
Scoggin, S.2
Gaynor, R.B.3
Williams, N.S.4
|