Role of two residues proximal to the active site of Ubc9 in substrate recognition by the Ubc9·SUMO-1 thiolester complex

Biochemistry

Volumn 42, Issue 11, 2003, Pages 3168-3179

  Tatham, Michael H ^a   Chen, Yuan ^b   Hay, Ronald T ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; PROTEINS; REACTION KINETICS; SUBSTRATES;

TRANSESTERIFICATION REACTIONS;

ESTERS;

ASPARTIC ACID; CYSTEINE; LYSINE; SUMO 1 PROTEIN; THIOESTER; UBIQUITIN C;

ARTICLE; CONJUGATION; CONTROLLED STUDY; ESTERIFICATION; HUMAN; KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; STEADY STATE;

AMINO ACID SEQUENCE; ANIMALS; ASPARTIC ACID; BASE SEQUENCE; BINDING SITES; CATALYSIS; CLONING, MOLECULAR; DNA PRIMERS; DNA, COMPLEMENTARY; ESTERS; HUMANS; KINETICS; LIGASES; LYSINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; SUMO-1 PROTEIN; UBIQUITIN-CONJUGATING ENZYMES;

EID: 0037465706     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026861x     Document Type: Article

References (32)

1. Pickart, C. M. (2000) Trends Biochem. Sci. 25, 544-548.
2. Muller, S., Hoege, C., Pyrowolakis, G., and Jentsch, S. (2001) Nat. Rev. Mol. Cell Biol. 2, 202-210.
3. Wilson, V. G., and Rangasamy, D. (2001) Exp. Cell Res. 271, 57-65.
4. Kim, K. I., Baek, S. H., and Chung, C. H. (2002) J. Cell Physiol. 191, 257-268.
5. Hochstrasser, M. (2000) Nat. Cell Biol. 2, E153-E157.
6. Hochstrasser, M. (2001) Cell 107, 5-8.
7. Bernier-Villamor, V., Sampson, D. A., Matunis, M. J., and Lima, C. D. (2002) Cell 108, 345-356.
8. Lin, D., Tatham, M. H., Yu, B., Kim, S., Hay, R. T., and Chen, Y. (2002) J. Biol. Chem. 277, 21740-21748.
9. Kolman, C. J., Toth, J., and Gonda, D. K. (1992) EMBO J. 11, 3081-3090.
10. Silver, E. T., Gwozd, T. J., Ptak, C., Goebl, M., and Ellison, M. J. (1992) EMBO J. 11, 3091-3098.
11. Tatham, M. H., Jaffray, E., Vaughan, O. A., Desterro, J. M., Botting, C. H., Naismith, J. H., and Hay, R. T. (2001) J. Biol. Chem. 276, 35368-35374.
12. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254.
13. Dang, Q., and Frieden, C. (1997) Trends Biochem. Sci. 22, 317.
14. Baboshina, O. V., Crinelli, R., Siepmann, T. J., and Haas, A. L. (2001) J. Biol. Chem. 276, 39428-39437.
15. Hofmann, R. M., and Pickart, C. M. (2001) J. Biol. Chem. 276, 27936-27943.
16. Dalziel, K. (1957) Acta Chem. Scand. 11, 1707-1723.
17. Giraud, M. F., Desterro, J. M., and Naismith, J. H. (1998) Acta Crystallogr. D54, 891-898.
18. Tong, H., Hateboer, G., Perrakis, A., Bernards, R., and Sixma, T. K. (1997) J. Biol. Chem. 272, 21381-21387.
19. Hamilton, K. S., Ellison, M. J., Barber, K. R., Williams, R. S., Huzil, J. T., McKenna, S., Ptak, C., Glover, M., and Shaw, G. S. (2001) Structure 9, 897-904.
20. Wee, K. E., Lai, Z., Auger, K. R., Ma, J., Horiuchi, K. Y., Dowling, R. L., Dougherty, C. S., Corman, J. I., Wynn, R., and Copeland, R. A. (2000) J. Protein Chem. 19, 489-498.
21. Liu, Q., Jin, C., Liao, X., Shen, Z., Chen, D. J., and Chen, Y. (1999) J. Biol. Chem. 274, 16979-16987.
22. Bencsath, K. P., Podgorski, M. S., Pagala, V. R., Slaughter, C. A., and Schulman, B. A. (2002) J. Biol. Chem. 277, 47938-47945.
23. Lin, H., and Wing, S. S. (1999) J. Biol. Chem. 274, 14685-14691.
24. Cook, W. J., Martin, P. D., Edwards, B. F., Yamazaki, R. K., and Chau, V. (1997) Biochemistry 36, 1621-1627.
25. Sachdev, S., Bruhn, L., Sieber, H., Pichler, A., Melchior, F., and Grosschedl, R. (2001) Genes Dev. 15, 3088-3103.
26. Johnson, E. S., and Gupta, A. A. (2001) Cell 106, 735-744.
27. Kotaja, N., Karvonen, U., Janne, O. A., and Palvimo, J. J. (2002) Mol. Cell. Biol. 22, 5222-5234.
28. Pichler, A., Gast, A., Seeler, J. S., Dejean, A., and Melchior, F. (2002) Cell 108, 109-120.
29. Takahashi, Y., Toh-e, A., and Kikuchi, Y. (2001) Gene 275, 223-231.
30. Azuma, Y., and Dasso, M. (2002) Dev. Cell 2, 130-131.
31. Kahyo, T., Nishida, T., and Yasuda, H. (2001) Mol. Cell 8, 713-718.
32. Press, W. H., Flannery, B. P., Teukolsky, S. A., and Vetterling, W. T. (1989) Numerical Recipes, Cambridge University Press, Cambridge, U.K.