메뉴 건너뛰기




Volumn 25, Issue 16, 2005, Pages 7021-7032

Human MMS21/NSE2 is a SUMO ligase required for DNA repair

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; ATR PROTEIN; CELL DNA; CELL PROTEIN; CHECKPOINT KINASE 2; FUNGAL PROTEIN; LIGASE; MMS21 LIGASE; MUTANT PROTEIN; NON SMC ELEMENT 2 LIGASE; STRUCTURAL MAINTENANCE OF CHROMOSOME 5 PROTEIN; STRUCTURAL MAINTENANCE OF CHROMOSOME 6 PROTEIN; SUMO PROTEIN; TRANSLIN ASSOCIATED FACTOR X PROTEIN; UNCLASSIFIED DRUG;

EID: 23344442009     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.16.7021-7032.2005     Document Type: Article
Times cited : (211)

References (51)
  • 1
    • 11144324990 scopus 로고    scopus 로고
    • Nse2, a component of the SmcS-6 complex, is a SUMO ligase required for the response to DNA damage
    • Andrews, E. A., J. Palecek, J. Sergeant, E. Taylor, A. R. Lehmann, and F. Z. Watts. 2005. Nse2, a component of the SmcS-6 complex, is a SUMO ligase required for the response to DNA damage. Mol. Cell. Biol. 25:185-196.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 185-196
    • Andrews, E.A.1    Palecek, J.2    Sergeant, J.3    Taylor, E.4    Lehmann, A.R.5    Watts, F.Z.6
  • 3
    • 1842486792 scopus 로고    scopus 로고
    • The spindle checkpoint, aneuploidy, and cancer
    • Bharadwaj, R., and H. Yu. 2004. The spindle checkpoint, aneuploidy, and cancer. Oncogene 23:2016-2027.
    • (2004) Oncogene , vol.23 , pp. 2016-2027
    • Bharadwaj, R.1    Yu, H.2
  • 4
    • 8544283254 scopus 로고    scopus 로고
    • The comet assay for DNA damage and repair: Principles, applications, and limitations
    • Collins, A. R. 2004. The comet assay for DNA damage and repair: principles, applications, and limitations. Mol. Biotechnol. 26:249-261.
    • (2004) Mol. Biotechnol. , vol.26 , pp. 249-261
    • Collins, A.R.1
  • 6
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S. M., J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl. 2001. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411:494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 7
    • 0034599577 scopus 로고    scopus 로고
    • A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein
    • Fousteri, M. I., and A. R. Lehmann. 2000. A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein. EMBO J. 19:1691-1702.
    • (2000) EMBO J. , vol.19 , pp. 1691-1702
    • Fousteri, M.I.1    Lehmann, A.R.2
  • 8
    • 0037077281 scopus 로고    scopus 로고
    • Identification of a novel non-structural maintenance of chromosomes (SMC) component of the SMC5-SMC6 complex involved in DNA repair
    • Fujioka, Y., Y. Kimata, K. Nomaguchi, K. Watanabe, and K. Kohno. 2002. Identification of a novel non-structural maintenance of chromosomes (SMC) component of the SMC5-SMC6 complex involved in DNA repair. J. Biol. Chem. 277:21585-21591.
    • (2002) J. Biol. Chem. , vol.277 , pp. 21585-21591
    • Fujioka, Y.1    Kimata, Y.2    Nomaguchi, K.3    Watanabe, K.4    Kohno, K.5
  • 9
    • 4444301185 scopus 로고    scopus 로고
    • SUMO and ubiquitin in the nucleus: Different functions, similar mechanisms?
    • Gill, G. 2004. SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? Genes Dev. 18:2046-2059.
    • (2004) Genes Dev. , vol.18 , pp. 2046-2059
    • Gill, G.1
  • 10
    • 14244249406 scopus 로고    scopus 로고
    • Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates
    • Gocke, C. B., H. Yu, and J. Kang. 2005. Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates. J. Biol. Chem. 280:5004-5012.
    • (2005) J. Biol. Chem. , vol.280 , pp. 5004-5012
    • Gocke, C.B.1    Yu, H.2    Kang, J.3
  • 11
    • 0038141196 scopus 로고    scopus 로고
    • Condensin and cohesin: More than chromosome compactor and glue
    • Hagstrom, K. A., and B. J. Meyer. 2003. Condensin and cohesin: more than chromosome compactor and glue. Nat. Rev. Genet. 4:520-534.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 520-534
    • Hagstrom, K.A.1    Meyer, B.J.2
  • 12
    • 0037086643 scopus 로고    scopus 로고
    • Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover
    • Hardeland, U., R. Steinacher, J. Jiricny, and P. Schar. 2002. Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover. EMBO J. 21:1456-1464.
    • (2002) EMBO J. , vol.21 , pp. 1456-1464
    • Hardeland, U.1    Steinacher, R.2    Jiricny, J.3    Schar, P.4
  • 13
  • 14
    • 0037084037 scopus 로고    scopus 로고
    • The ABCs of SMC proteins: Two-armed ATPases for chromosome condensation, cohesion, and repair
    • Hirano, T. 2002. The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair. Genes Dev. 16:399-414.
    • (2002) Genes Dev. , vol.16 , pp. 399-414
    • Hirano, T.1
  • 15
    • 0035886518 scopus 로고    scopus 로고
    • SUMO modification of Rad22, the Schizosaccharomyces pombe homologue of the recombination protein Rad52
    • Ho, J. C., N. J. Warr, H. Shimizu, and F. Z. Watts. 2001. SUMO modification of Rad22, the Schizosaccharomyces pombe homologue of the recombination protein Rad52. Nucleic Acids Res. 29:4179-4186.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 4179-4186
    • Ho, J.C.1    Warr, N.J.2    Shimizu, H.3    Watts, F.Z.4
  • 16
    • 0037068455 scopus 로고    scopus 로고
    • RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
    • Hoege, C., B. Pfander, G. L. Moldovan, G. Pyrowolakis, and S. Jentsch. 2002. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419:135-141.
    • (2002) Nature , vol.419 , pp. 135-141
    • Hoege, C.1    Pfander, B.2    Moldovan, G.L.3    Pyrowolakis, G.4    Jentsch, S.5
  • 18
    • 3943099375 scopus 로고    scopus 로고
    • Protein modification by SUMO
    • Johnson, E. S. 2004. Protein modification by SUMO. Annu. Rev. Biochem. 73:355-382.
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 355-382
    • Johnson, E.S.1
  • 19
    • 0035929279 scopus 로고    scopus 로고
    • An E3-like factor that promotes SUMO conjugation to the yeast septins
    • Johnson, E. S., and A. A. Gupta. 2001. An E3-like factor that promotes SUMO conjugation to the yeast septins. Cell 106:735-744.
    • (2001) Cell , vol.106 , pp. 735-744
    • Johnson, E.S.1    Gupta, A.A.2
  • 20
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • Kastan, M. B., and J. Bartek. 2004. Cell-cycle checkpoints and cancer. Nature 432:316-323.
    • (2004) Nature , vol.432 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 21
    • 0035093737 scopus 로고    scopus 로고
    • DNA double-strand breaks: Signaling, repair and the cancer connection
    • Khanna, K. K., and S. P. Jackson. 2001. DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet. 27:247-254.
    • (2001) Nat. Genet. , vol.27 , pp. 247-254
    • Khanna, K.K.1    Jackson, S.P.2
  • 22
    • 0033621392 scopus 로고    scopus 로고
    • Substrate specificities and identification of putative substrates of ATM kinase family members
    • Kim, S. T., D. S. Lim, C. E. Canman, and M. B. Kastan. 1999. Substrate specificities and identification of putative substrates of ATM kinase family members. J. Biol. Chem. 274:37538-37543.
    • (1999) J. Biol. Chem. , vol.274 , pp. 37538-37543
    • Kim, S.T.1    Lim, D.S.2    Canman, C.E.3    Kastan, M.B.4
  • 23
    • 0034020066 scopus 로고    scopus 로고
    • Sister chromatid cohesion: The beginning of a long and beautiful relationship
    • Koshland, D. E., and V. Guacci. 2000. Sister chromatid cohesion: the beginning of a long and beautiful relationship. Curr. Opin. Cell Biol. 12:297-301.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 297-301
    • Koshland, D.E.1    Guacci, V.2
  • 24
    • 0028850628 scopus 로고
    • The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair
    • Lehmann, A. R., M. Walicka, D. J. Griffiths, J. M. Murray, F. Z. Watts, S. McCready, and A. M. Carr. 1995. The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair. Mol. Cell. Biol. 15:7067-7080.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 7067-7080
    • Lehmann, A.R.1    Walicka, M.2    Griffiths, D.J.3    Murray, J.M.4    Watts, F.Z.5    McCready, S.6    Carr, A.M.7
  • 25
    • 4544281398 scopus 로고    scopus 로고
    • Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins
    • Lisby, M., J. H. Barlow, R. C. Burgess, and R. Rothstein. 2004. Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins. Cell 118:699-713.
    • (2004) Cell , vol.118 , pp. 699-713
    • Lisby, M.1    Barlow, J.H.2    Burgess, R.C.3    Rothstein, R.4
  • 26
    • 2342527027 scopus 로고    scopus 로고
    • DNA damage checkpoint and repair centers
    • Lisby, M., and R. Rothstein. 2004. DNA damage checkpoint and repair centers. Curr. Opin. Cell Biol. 16:328-334.
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 328-334
    • Lisby, M.1    Rothstein, R.2
  • 27
    • 0842281642 scopus 로고    scopus 로고
    • Ubc9 is required for damage-tolerance and damage-induced interchromosomal homologous recombination in S. cerevisiae
    • Maeda, D., M. Seki, F. Onoda, D. Branzei, Y. Kawabe, and T. Enomoto. 2004. Ubc9 is required for damage-tolerance and damage-induced interchromosomal homologous recombination in S. cerevisiae. DNA Repair (Amsterdam) 3:335-341.
    • (2004) DNA Repair (Amsterdam) , vol.3 , pp. 335-341
    • Maeda, D.1    Seki, M.2    Onoda, F.3    Branzei, D.4    Kawabe, Y.5    Enomoto, T.6
  • 28
    • 0034635958 scopus 로고    scopus 로고
    • SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage
    • Mao, Y., M. Sun, S. D. Desai, and L. F. Liu. 2000. SUMO-1 conjugation to topoisomerase I: a possible repair response to topoisomerase-mediated DNA damage. Proc. Natl. Acad. Sci. USA 97:4046-4051.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 4046-4051
    • Mao, Y.1    Sun, M.2    Desai, S.D.3    Liu, L.F.4
  • 29
    • 0242413170 scopus 로고    scopus 로고
    • Novel essential DNA repair proteins Nse1 and Nse2 are subunits of the fission yeast Smc5-Smc6 complex
    • McDonald, W. H., Y. Pavlova, J. R. Yates III, and M. N. Boddy. 2003. Novel essential DNA repair proteins Nse1 and Nse2 are subunits of the fission yeast Smc5-Smc6 complex. J. Biol. Chem. 278:45460-45467.
    • (2003) J. Biol. Chem. , vol.278 , pp. 45460-45467
    • McDonald, W.H.1    Pavlova, Y.2    Yates III, J.R.3    Boddy, M.N.4
  • 30
    • 0034306332 scopus 로고    scopus 로고
    • Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1
    • Melchionna, R., X. B. Chen, A. Blasina, and C. H. McGowan. 2000. Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1. Nat. Cell Biol. 2:762-765.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 762-765
    • Melchionna, R.1    Chen, X.B.2    Blasina, A.3    McGowan, C.H.4
  • 31
    • 0028947827 scopus 로고
    • Interactions among mutations affecting spontaneous mutation, mitotic recombination, and DNA repair in yeast
    • Montelone, B. A., and K. J. Koelliker. 1995. Interactions among mutations affecting spontaneous mutation, mitotic recombination, and DNA repair in yeast. Curr. Genet. 27:102-109.
    • (1995) Curr. Genet. , vol.27 , pp. 102-109
    • Montelone, B.A.1    Koelliker, K.J.2
  • 32
    • 6344291070 scopus 로고    scopus 로고
    • Rad62 protein functionally and physically associates with the Smc5/Smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast
    • Morikawa, H., T. Morishita, S. Kawane, H. Iwasaki, A. M. Carr, and H. Shinagawa. 2004. Rad62 protein functionally and physically associates with the Smc5/Smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast. Mol. Cell. Biol. 24:9401-9413.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9401-9413
    • Morikawa, H.1    Morishita, T.2    Kawane, S.3    Iwasaki, H.4    Carr, A.M.5    Shinagawa, H.6
  • 33
    • 0037178719 scopus 로고    scopus 로고
    • Segregating sister genomes: The molecular biology of chromosome separation
    • Nasmyth, K. 2002. Segregating sister genomes: the molecular biology of chromosome separation. Science 297:559-565.
    • (2002) Science , vol.297 , pp. 559-565
    • Nasmyth, K.1
  • 34
    • 1542269014 scopus 로고    scopus 로고
    • SMC6 is required for MMS-induced interchromosomal and sister chromatid recombinations in Saccharomyces cerevisiae
    • Onoda, F., M. Takeda, M. Seki, D. Maeda, J. Tajima, A. Ui, H. Yagi, and T. Enomoto. 2004. SMC6 is required for MMS-induced interchromosomal and sister chromatid recombinations in Saccharomyces cerevisiae. DNA Repair (Amsterdam) 3:429-439.
    • (2004) DNA Repair (Amsterdam) , vol.3 , pp. 429-439
    • Onoda, F.1    Takeda, M.2    Seki, M.3    Maeda, D.4    Tajima, J.5    Ui, A.6    Yagi, H.7    Enomoto, T.8
  • 35
    • 6344268940 scopus 로고    scopus 로고
    • Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis
    • Pebernard, S., W. H. McDonald, Y. Pavlova, J. R. Yates III, and M. N. Boddy. 2004. Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis. Mol. Biol. Cell 15:4866-4876.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 4866-4876
    • Pebernard, S.1    McDonald, W.H.2    Pavlova, Y.3    Yates III, J.R.4    Boddy, M.N.5
  • 36
    • 0037459072 scopus 로고    scopus 로고
    • Un menage a quatre: The molecular biology of chromosome segregation in meiosis
    • Petronczki, M., M. F. Siomos, and K. Nasmyth. 2003. Un menage a quatre: the molecular biology of chromosome segregation in meiosis. Cell 112:423-440.
    • (2003) Cell , vol.112 , pp. 423-440
    • Petronczki, M.1    Siomos, M.F.2    Nasmyth, K.3
  • 37
    • 0037059619 scopus 로고    scopus 로고
    • The nucleoporin RanBP2 has SUMO1 E3 ligase activity
    • Pichler, A., A. Gast, J. S. Seeler, A. Dejean, and F. Melchior. 2002. The nucleoporin RanBP2 has SUMO1 E3 ligase activity. Cell 108:109-120.
    • (2002) Cell , vol.108 , pp. 109-120
    • Pichler, A.1    Gast, A.2    Seeler, J.S.3    Dejean, A.4    Melchior, F.5
  • 38
    • 0017409010 scopus 로고
    • Isolation and characterization of MMS-sensitive mutants of Saccharomyces cerevisiae
    • Prakash, L., and S. Prakash. 1977. Isolation and characterization of MMS-sensitive mutants of Saccharomyces cerevisiae. Genetics 86:33-55.
    • (1977) Genetics , vol.86 , pp. 33-55
    • Prakash, L.1    Prakash, S.2
  • 39
    • 0017752583 scopus 로고
    • Increased spontaneous mitotic segregation in MMS-sensitive mutants of Saccharomyces cerevisiae
    • Prakash, S., and L. Prakash. 1977. Increased spontaneous mitotic segregation in MMS-sensitive mutants of Saccharomyces cerevisiae. Genetics 87:229-236.
    • (1977) Genetics , vol.87 , pp. 229-236
    • Prakash, S.1    Prakash, L.2
  • 40
    • 9244263076 scopus 로고    scopus 로고
    • Aneuploidy and cancer
    • Rajagopalan, H., and C. Lengauer. 2004. Aneuploidy and cancer. Nature 432:338-341.
    • (2004) Nature , vol.432 , pp. 338-341
    • Rajagopalan, H.1    Lengauer, C.2
  • 41
    • 3943107573 scopus 로고    scopus 로고
    • Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
    • Sancar, A., L. A. Lindsey-Boltz, K. Unsal-Kacmaz, and S. Linn. 2004. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu. Rev. Biochem. 73:39-85.
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 39-85
    • Sancar, A.1    Lindsey-Boltz, L.A.2    Unsal-Kacmaz, K.3    Linn, S.4
  • 43
    • 0141831006 scopus 로고    scopus 로고
    • Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation
    • Stelter, P., and H. D. Ulrich. 2003. Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation. Nature 425:188-191.
    • (2003) Nature , vol.425 , pp. 188-191
    • Stelter, P.1    Ulrich, H.D.2
  • 44
    • 0037349338 scopus 로고    scopus 로고
    • The making of the mitotic chromosome: Modern insights into classical questions
    • Swedlow, J. R., and T. Hirano. 2003. The making of the mitotic chromosome: modern insights into classical questions. Mol. Cell 11:557-569.
    • (2003) Mol. Cell , vol.11 , pp. 557-569
    • Swedlow, J.R.1    Hirano, T.2
  • 45
    • 0037087504 scopus 로고    scopus 로고
    • Cell-cycle-dependent localisation of Ulp1, a Schizosaccharomyces pombe Pmt3 (SUMO)-specific protease
    • Taylor, D. L., J. C. Ho, A. Oliver, and F. Z. Watts. 2002. Cell-cycle-dependent localisation of Ulp1, a Schizosaccharomyces pombe Pmt3 (SUMO)-specific protease. J. Cell Sci. 115:1113-1122.
    • (2002) J. Cell Sci. , vol.115 , pp. 1113-1122
    • Taylor, D.L.1    Ho, J.C.2    Oliver, A.3    Watts, F.Z.4
  • 46
    • 0035167402 scopus 로고    scopus 로고
    • Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex
    • Taylor, E. M., J. S. Moghraby, J. H. Lees, B. Smit, P. B. Moens, and A. R. Lehmann. 2001. Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex. Mol. Biol. Cell 12:1583-1594.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 1583-1594
    • Taylor, E.M.1    Moghraby, J.S.2    Lees, J.H.3    Smit, B.4    Moens, P.B.5    Lehmann, A.R.6
  • 48
    • 0035930536 scopus 로고    scopus 로고
    • Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks
    • Ward, I. M., X. Wu, and J. Chen. 2001. Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks. J. Biol. Chem. 276:47755-47758.
    • (2001) J. Biol. Chem. , vol.276 , pp. 47755-47758
    • Ward, I.M.1    Wu, X.2    Chen, J.3
  • 49
    • 0038700698 scopus 로고    scopus 로고
    • Molecular views of recombination proteins and their control
    • West, S. C. 2003. Molecular views of recombination proteins and their control. Nat. Rev. Mol. Cell Biol. 4:435-445.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 435-445
    • West, S.C.1
  • 50
    • 16344370926 scopus 로고    scopus 로고
    • A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization
    • Zhao, X., and G. Blobel. 2005. A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc. Natl. Acad. Sci. USA 102:4661-4662.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 4661-4662
    • Zhao, X.1    Blobel, G.2
  • 51
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: Putting checkpoints in perspective
    • Zhou, B. B., and S. J. Elledge. 2000. The DNA damage response: putting checkpoints in perspective. Nature 408:433-439.
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.