Sustained transgene expression using non-viral enzymatic systems for stable chromosomal integration

Current Gene Therapy

Volumn 8, Issue 5, 2008, Pages 367-390

  Palazzoli, Fabien ^a,b   Carnus, Elodie ^a,b   Wells, Dominic J ^d   Bigot, Yves ^a,b,c  

^a UNIVERSITÉ DE TOURS   (France)

^b CNRS   (France)

^c UNIVERSITY HOSPITAL OF TOURS   (France)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Integrase; Meganuclease; Nuclease; Recombination; Targeting; Transposase; Transposon

Indexed keywords

ENDONUCLEASE; FROG PRINCE PROTEIN; INTEGRASE; MARINER LIKE ELEMENT; MEGANUCLEASE; MESSENGER RNA; MINOS PROTEIN; PHOSPHOTRANSFERASE; PIGGYBAC PROTEIN; POLYDACTYL ZINC FINGER NUCLEASE; PROTEIN ISY 100; PROTEIN TN7; RECOMBINASE; RIBOSOME RNA; SLEEPING BEAUTY PROTEIN; TOL2 PROTEIN; TRANSPOSASE; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE; UNCLASSIFIED DRUG; RECOMBINANT DNA;

CHROMOSOMAL INSTABILITY; CHROMOSOME ANALYSIS; DNA INTEGRATION; DNA MODIFICATION; DNA SEQUENCE; DOUBLE STRANDED DNA BREAK; ENZYME SYNTHESIS; GENE CASSETTE; GENE CONSTRUCT; GENE EXPRESSION; GENE INSERTION; GENE TARGETING; GENE TRANSLOCATION; GENOTOXICITY; HOMOLOGOUS RECOMBINATION; HUMAN; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; POINT MUTATION; REVIEW; SINGLE STRANDED DNA BREAK; TRANSGENE; TRANSPOSON; ANIMAL; GENE THERAPY; GENE VECTOR; GENETIC RECOMBINATION; GENETICS; HUMAN CHROMOSOME; METHODOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PATENT;

ANIMALS; BASE SEQUENCE; CHROMOSOMES, HUMAN; DNA, RECOMBINANT; ENDONUCLEASES; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; HUMANS; INTEGRASES; INTELLECTUAL PROPERTY; MOLECULAR SEQUENCE DATA; RECOMBINASES; RECOMBINATION, GENETIC; TRANSPOSASES;

EID: 59249093855     PISSN: 15665232     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652308786070970     Document Type: Review

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