Sleeping beauty, a wide host-range transposon vector for genetic trensformation in vertebrates

Journal of Molecular Biology

Volumn 302, Issue 1, 2000, Pages 93-102

  Izsvák, Zsuzsanna ^b,c   Ivics, Zoltán ^b   Plasterk, Ronald H ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

DNA binding; Transgenic; Transposable element; Transposition; Vertebrates

Indexed keywords

ANIMAL CELL; ARTICLE; BINDING SITE; CLONING VECTOR; DNA SEQUENCE; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENE INSERTION; GENE OVEREXPRESSION; GENETIC TRANSFORMATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; TRANSPOSON; VERTEBRATE;

ANIMALIA; VERTEBRATA;

EID: 0034623009     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4047     Document Type: Article

References (26)

1. DNA-promoted assembly of the active tetramer of the Mu transposase
2. DNA binding activities of the Caenorhabditis elegans Tc3 transposase
3. Genetic analysis of the interaction of the insertion sequence IS903 transposase with its terminal inverted repeats
4. Cis requirements for transposition of Tc1-like transposons in C
5. Minos, a new transposable element from Drosophila hydei, is a member of the Tc1-like family of transposons
6. What restricts the activity of mariner-like transposable elements?
7. Identification of functional domains and evolution of Tc1-like transposable elements
8. Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
9. Characterization of a Tc1-like transposable element in zebrafish (Danio rerio)
10. Quetzal: A transposon of the Tc1 family in the mosquito Anopheles albimanus
11. mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD
12. Discovery of amphibian Tc1-like transposon families
13. A purified mariner transposase is sufficient to mediate transposition in vitro
14. Factors affecting transposition of the Himar1 mariner transposon in vitro
15. Development of expression vectors for transgenic fish
16. Autoregulation of mariner transposase activity by overproduction and cominant-negative complementation
17. Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells
18. S elements: A family of Tc1-like transposons in the genome of Drosophila melanogaster
19. Intra- and interspecies variation among Bari-1 elements of the melanogaster species group
20. Resident aliens: The Tc1/mariner superfamily of transposable elements
21. Evidence for Drosophila P element ransposase activity in mammalian cells and yeast
22. The rde-1 gene, RNA interference, and transposon silencing in C. elegans
23. Transposase is the only nematode protein required for n vitro transposition of Tc1
24. Transposition of plasmid-borne Tn10 elements does not exhibit simple length-dependence
25. Somatic integration and longterm transgene expression in normal and haemophilic mice using a DNA transposon system