Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: Critical residues for DNA binding and hyperactivity in mammalian cells

Molecular and Cellular Biology

Volumn 24, Issue 20, 2004, Pages 9239-9247

  Yant, Stephen R ^a   Park, Julie ^a   Huang, Yong ^a   Mikkelsen, Jacob Giehm ^a   Kay, Mark A ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; DNA; GLYCINE; ISOLEUCINE; LEUCINE; MUTANT PROTEIN; TRANSPOSASE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHROMOSOME TRANSLOCATION; DNA BINDING MOTIF; DNA CLEAVAGE; DNA TRANSPOSITION; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE TRANSFER; GENE VECTOR; HUMAN; HUMAN CELL; MAMMAL CELL; MISSENSE MUTATION; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUCLEAR LOCALIZATION SIGNAL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DNA BINDING; QUANTITATIVE ASSAY; TRANSPOSON;

AMINO ACID SEQUENCE; ANIMALS; DNA; DNA MUTATIONAL ANALYSIS; DNA TRANSPOSABLE ELEMENTS; HELA CELLS; HUMANS; MICE; MICE, INBRED C57BL; MICE, SCID; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; TRANSPOSASES;

ANIMALIA; MAMMALIA; TRANSPOSONS; VERTEBRATA;

EID: 4744374701     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.20.9239-9247.2004     Document Type: Article

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