Custom zinc-finger nucleases for use in human cells

Molecular Therapy

Volumn 12, Issue 4, 2005, Pages 610-617

  Alwin, Stephen ^a   Gere, Maja B ^a   Guhl, Eva ^a   Effertz, Karin ^b   Barbas III, Carlos F ^b   Segal, David J ^c   Weitzman, Matthew D ^d   Cathomen, Toni ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Artificial endonucleases; Chimeric nucleases; Gene correction; Site directed recombination; Zinc Finger

Indexed keywords

DOUBLE STRANDED RNA; ENDONUCLEASE; ZINC FINGER PROTEIN;

APOPTOSIS; ARTICLE; BINDING SITE; CELL SURVIVAL; CHROMOSOME; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DNA REPAIR; GENETIC DISORDER; GENETIC ENGINEERING; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MAMMAL CELL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION;

BASE SEQUENCE; BINDING SITES; DNA; DNA NUCLEOTIDYLTRANSFERASES; DNA REPAIR; DNA-BINDING PROTEINS; ENDONUCLEASES; GENE TARGETING; HUMANS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RECOMBINATION, GENETIC; ZINC FINGERS;

MAMMALIA;

EID: 25144501447     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2005.06.094     Document Type: Article

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