-
1
-
-
0035955628
-
De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase
-
Ackermann M., and Padmanabhan R. De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase. J. Biol. Chem. 276 (2001) 39926-39937
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39926-39937
-
-
Ackermann, M.1
Padmanabhan, R.2
-
2
-
-
34247625945
-
Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold
-
Aleshin A.E., Shiryaev S.A., Strongin A.Y., and Liddington R.C. Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold. Protein Sci. 16 (2007) 795-806
-
(2007)
Protein Sci.
, vol.16
, pp. 795-806
-
-
Aleshin, A.E.1
Shiryaev, S.A.2
Strongin, A.Y.3
Liddington, R.C.4
-
3
-
-
0028815675
-
Oligomeric rearrangement of tick-borne encephalitis-virus envelope proteins induced by an acidic pH
-
Allison S.L., Schalich J., Stiasny K., Mandl C.W., Kunz C., and Heinz F.X. Oligomeric rearrangement of tick-borne encephalitis-virus envelope proteins induced by an acidic pH. J. Virol. 69 (1995) 695-700
-
(1995)
J. Virol.
, vol.69
, pp. 695-700
-
-
Allison, S.L.1
Schalich, J.2
Stiasny, K.3
Mandl, C.W.4
Kunz, C.5
Heinz, F.X.6
-
4
-
-
0027285404
-
Dengue-2 virus NS2b and NS3 form a stable complex that can cleave NS3 within the helicase domain
-
Arias C.F., Preugschat F., and Strauss J.H. Dengue-2 virus NS2b and NS3 form a stable complex that can cleave NS3 within the helicase domain. Virology 193 (1993) 888-899
-
(1993)
Virology
, vol.193
, pp. 888-899
-
-
Arias, C.F.1
Preugschat, F.2
Strauss, J.H.3
-
5
-
-
27744510434
-
Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes
-
Barba-Spaeth G., Longman R.S., Albert M.L., and Rice C.M. Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes. J. Exp. Med. 202 (2005) 1179-1184
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1179-1184
-
-
Barba-Spaeth, G.1
Longman, R.S.2
Albert, M.L.3
Rice, C.M.4
-
6
-
-
34447271709
-
Sultam thiourea inhibition of West Nile virus
-
Barklis E., Still A., Sabri M.I., Hirsch A.J., Nikolich-Zugich J., Brien J., Dhenub T.C., Scholz I., and Alfadhli A. Sultam thiourea inhibition of West Nile virus. Antimicrob. Agents Chemother. 51 (2007) 2642-2645
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, pp. 2642-2645
-
-
Barklis, E.1
Still, A.2
Sabri, M.I.3
Hirsch, A.J.4
Nikolich-Zugich, J.5
Brien, J.6
Dhenub, T.C.7
Scholz, I.8
Alfadhli, A.9
-
7
-
-
0027349993
-
Synthesis of dengue virus RNA in vitro-initiation and the involvement of proteins NS3 and NS5
-
Bartholomeusz A.I., and Wright P.J. Synthesis of dengue virus RNA in vitro-initiation and the involvement of proteins NS3 and NS5. Arch. Virol. 128 (1993) 111-121
-
(1993)
Arch. Virol.
, vol.128
, pp. 111-121
-
-
Bartholomeusz, A.I.1
Wright, P.J.2
-
8
-
-
0024372153
-
Detection of a trypsin-like serine protease domain in flaviviruses and pestiviruses
-
Bazan J.F., and Fletterick R.J. Detection of a trypsin-like serine protease domain in flaviviruses and pestiviruses. Virology 171 (1989) 637-639
-
(1989)
Virology
, vol.171
, pp. 637-639
-
-
Bazan, J.F.1
Fletterick, R.J.2
-
10
-
-
34250346935
-
Functional characterization of cis and trans activity of the Flavivirus NS2B-NS3 protease
-
Bera A.K., Kuhn R.J., and Smith J.L. Functional characterization of cis and trans activity of the Flavivirus NS2B-NS3 protease. J. Biol. Chem. 282 (2007) 12883-12892
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 12883-12892
-
-
Bera, A.K.1
Kuhn, R.J.2
Smith, J.L.3
-
11
-
-
0030761459
-
Translation elongation factor-1 alpha interacts with the 3' stem-loop region of West Nile virus genomic RNA
-
Blackwell J.L., and Brinton M.A. Translation elongation factor-1 alpha interacts with the 3' stem-loop region of West Nile virus genomic RNA. J Virol. 71 (1997) 6433-6444
-
(1997)
J Virol.
, vol.71
, pp. 6433-6444
-
-
Blackwell, J.L.1
Brinton, M.A.2
-
12
-
-
0036237524
-
Characterization of imidazo 4,5-d pyridazine nucleosides as modulators of unwinding reaction mediated by West Nile virus nucleoside triphosphatase/helicase: evidence for activity on the level of substrate and/or enzyme
-
Borowski P., Lang M., Haag A., Schmitz H., Choe J., Chen H.M., and Hosmane R.S. Characterization of imidazo 4,5-d pyridazine nucleosides as modulators of unwinding reaction mediated by West Nile virus nucleoside triphosphatase/helicase: evidence for activity on the level of substrate and/or enzyme. Antimicrob. Agents Chemother. 46 (2002) 1231-1239
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 1231-1239
-
-
Borowski, P.1
Lang, M.2
Haag, A.3
Schmitz, H.4
Choe, J.5
Chen, H.M.6
Hosmane, R.S.7
-
13
-
-
0038747996
-
Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses
-
Borowski P., Deinert J., Schalinski S., Bretner M., Ginalski K., Kulikowski T., and Shugar D. Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses. Eur. J. Biochem. 270 (2003) 1645-1653
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 1645-1653
-
-
Borowski, P.1
Deinert, J.2
Schalinski, S.3
Bretner, M.4
Ginalski, K.5
Kulikowski, T.6
Shugar, D.7
-
14
-
-
34249311631
-
Tropolone and its derivatives as inhibitors of the helicase activity of hepatitis C virus nucleotide triphosphatase/helicase
-
Borowski P., Lang M., Haag A., and Baier A. Tropolone and its derivatives as inhibitors of the helicase activity of hepatitis C virus nucleotide triphosphatase/helicase. Antivir. Chem. Chemother. 18 (2007) 103-109
-
(2007)
Antivir. Chem. Chemother.
, vol.18
, pp. 103-109
-
-
Borowski, P.1
Lang, M.2
Haag, A.3
Baier, A.4
-
15
-
-
40849120543
-
Highly pathogenic RNA viral infections: challenges for antiviral research
-
Bray M. Highly pathogenic RNA viral infections: challenges for antiviral research. Antiviral Res. 78 (2008) 1-8
-
(2008)
Antiviral Res.
, vol.78
, pp. 1-8
-
-
Bray, M.1
-
16
-
-
0034096583
-
Treatment of lethal Ebola virus infection in mice with a single dose of an S-adenosyl-l-homocysteine hydrolase inhibitor
-
Bray M., Driscoll J., and Huggins J.W. Treatment of lethal Ebola virus infection in mice with a single dose of an S-adenosyl-l-homocysteine hydrolase inhibitor. Antiviral Res. 45 (2000) 135-147
-
(2000)
Antiviral Res.
, vol.45
, pp. 135-147
-
-
Bray, M.1
Driscoll, J.2
Huggins, J.W.3
-
17
-
-
0038455829
-
Basic science priorities for therapeutics research
-
Bridges S. Basic science priorities for therapeutics research. Res. Initiat. Treat. Action 8 (2003) 25-27
-
(2003)
Res. Initiat. Treat. Action
, vol.8
, pp. 25-27
-
-
Bridges, S.1
-
18
-
-
0035683926
-
Host factors involved in West Nile virus replication
-
Brinton M.A. Host factors involved in West Nile virus replication. Ann N Y Acad Sci. 951 (2001) 207-219
-
(2001)
Ann N Y Acad Sci.
, vol.951
, pp. 207-219
-
-
Brinton, M.A.1
-
19
-
-
0035208293
-
The mechanism of action of ribavirin: lethal mutagenesis of RNA virus genomes mediated by the viral RNA-dependent RNA polymerase
-
Cameron C.E., and Castro C. The mechanism of action of ribavirin: lethal mutagenesis of RNA virus genomes mediated by the viral RNA-dependent RNA polymerase. Curr. Opin. Infect. Dis. 14 (2001) 757-764
-
(2001)
Curr. Opin. Infect. Dis.
, vol.14
, pp. 757-764
-
-
Cameron, C.E.1
Castro, C.2
-
20
-
-
0035145352
-
The potential for HIV fusion inhibition
-
Cammack N. The potential for HIV fusion inhibition. Curr. Opin. Infect. Dis. 14 (2001) 13-16
-
(2001)
Curr. Opin. Infect. Dis.
, vol.14
, pp. 13-16
-
-
Cammack, N.1
-
21
-
-
33750991616
-
Synthesis and in vitro evaluation of the anti-viral activity of N-[4-(1H(2H)-benzotriazol-1(2)-yl)phenyl]alkylcarboxamides
-
Carta A., Loriga G., Piras S., Paglietti G., Ferrone M., Fermeglia M., Pricl S., La Colla P., Secci B., Collu G., and Loddo R. Synthesis and in vitro evaluation of the anti-viral activity of N-[4-(1H(2H)-benzotriazol-1(2)-yl)phenyl]alkylcarboxamides. Med. Chem. 2 (2006) 577-589
-
(2006)
Med. Chem.
, vol.2
, pp. 577-589
-
-
Carta, A.1
Loriga, G.2
Piras, S.3
Paglietti, G.4
Ferrone, M.5
Fermeglia, M.6
Pricl, S.7
La Colla, P.8
Secci, B.9
Collu, G.10
Loddo, R.11
-
22
-
-
0025201350
-
Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein
-
Chambers T.J., Weir R.C., Grakoui A., McCourt D.W., Bazan J.F., Fletterick R.J., and Rice C.M. Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 8898-8902
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 8898-8902
-
-
Chambers, T.J.1
Weir, R.C.2
Grakoui, A.3
McCourt, D.W.4
Bazan, J.F.5
Fletterick, R.J.6
Rice, C.M.7
-
23
-
-
0026039916
-
Processing of the yellow fever virus nonstructural polyprotein: a catalytically active NS3 proteinase domain and NS2B are required for cleavages at dibasic sites
-
Chambers T.J., Grakoui A., and Rice C.M. Processing of the yellow fever virus nonstructural polyprotein: a catalytically active NS3 proteinase domain and NS2B are required for cleavages at dibasic sites. J. Virol. 65 (1991) 6042-6050
-
(1991)
J. Virol.
, vol.65
, pp. 6042-6050
-
-
Chambers, T.J.1
Grakoui, A.2
Rice, C.M.3
-
24
-
-
0027486484
-
Mutagenesis of the yellow fever virus NS2B protein: effects on proteolytic processing, NS2B-NS3 complex formation, and viral replication
-
Chambers T.J., Nestorowicz A., Amberg S.M., and Rice C.M. Mutagenesis of the yellow fever virus NS2B protein: effects on proteolytic processing, NS2B-NS3 complex formation, and viral replication. J. Virol. 67 (1993) 6797-6807
-
(1993)
J. Virol.
, vol.67
, pp. 6797-6807
-
-
Chambers, T.J.1
Nestorowicz, A.2
Amberg, S.M.3
Rice, C.M.4
-
25
-
-
17044395894
-
Competitive inhibition of the dengue virus NS3 serine protease by synthetic peptides representing polyprotein cleavage sites
-
Chanprapaph S., Saparpakorn P., Sangma C., Niyomrattanakit P., Hannongbua S., Angsuthanasombat C., and Katzenmeier G. Competitive inhibition of the dengue virus NS3 serine protease by synthetic peptides representing polyprotein cleavage sites. Biochem. Biophys. Res. Commun. 330 (2005) 1237-1246
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.330
, pp. 1237-1246
-
-
Chanprapaph, S.1
Saparpakorn, P.2
Sangma, C.3
Niyomrattanakit, P.4
Hannongbua, S.5
Angsuthanasombat, C.6
Katzenmeier, G.7
-
26
-
-
13244281716
-
Site-directed mutagenesis and kinetic studies of the West Nile Virus NS3 protease identify key enzyme-substrate interactions
-
Chappell K.J., Nall T.A., Stoermer M.J., Fang N.X., Tyndall J.D., Fairlie D.P., and Young P.R. Site-directed mutagenesis and kinetic studies of the West Nile Virus NS3 protease identify key enzyme-substrate interactions. J. Biol. Chem. 280 (2005) 2896-2903
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 2896-2903
-
-
Chappell, K.J.1
Nall, T.A.2
Stoermer, M.J.3
Fang, N.X.4
Tyndall, J.D.5
Fairlie, D.P.6
Young, P.R.7
-
27
-
-
33845976698
-
Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies
-
Chappell K.J., Stoermer M.J., Fairlie D.P., and Young P.R. Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies. J. Biol. Chem. 281 (2006) 38448-38458
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 38448-38458
-
-
Chappell, K.J.1
Stoermer, M.J.2
Fairlie, D.P.3
Young, P.R.4
-
28
-
-
33847168016
-
Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3
-
Chappell K.J., Stoermer M.J., Fairlie D.P., and Young P.R. Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3. Protein Exp. Purif. 53 (2007) 87-96
-
(2007)
Protein Exp. Purif.
, vol.53
, pp. 87-96
-
-
Chappell, K.J.1
Stoermer, M.J.2
Fairlie, D.P.3
Young, P.R.4
-
29
-
-
4043140091
-
Rodent models for the study of therapy against flavivirus infections
-
Charlier N., Leyssen P., De Clercq E., and Neyts J. Rodent models for the study of therapy against flavivirus infections. Antiviral Res. 63 (2004) 67-77
-
(2004)
Antiviral Res.
, vol.63
, pp. 67-77
-
-
Charlier, N.1
Leyssen, P.2
De Clercq, E.3
Neyts, J.4
-
30
-
-
0023101499
-
Characterization of Kunjin virus RNA-dependent RNA-polymerase-reinitiation of synthesis in vitro
-
Chu P.W.G., and Westaway E.G. Characterization of Kunjin virus RNA-dependent RNA-polymerase-reinitiation of synthesis in vitro. Virology 157 (1987) 330-337
-
(1987)
Virology
, vol.157
, pp. 330-337
-
-
Chu, P.W.G.1
Westaway, E.G.2
-
31
-
-
0026494350
-
Molecular and ultrastructural analysis of heavy membrane-fractions associated with the replication of Kunjin virus RNA
-
Chu P.W.G., and Westaway E.G. Molecular and ultrastructural analysis of heavy membrane-fractions associated with the replication of Kunjin virus RNA. Arch. Virol. 125 (1992) 177-191
-
(1992)
Arch. Virol.
, vol.125
, pp. 177-191
-
-
Chu, P.W.G.1
Westaway, E.G.2
-
32
-
-
33845718113
-
Novel inhibitors of the early steps of the HIV-1 life cycle
-
Citterio P., and Rusconi S. Novel inhibitors of the early steps of the HIV-1 life cycle. Exp. Opin. Investig. Drugs 16 (2007) 11-23
-
(2007)
Exp. Opin. Investig. Drugs
, vol.16
, pp. 11-23
-
-
Citterio, P.1
Rusconi, S.2
-
33
-
-
0030667792
-
Cotranslational membrane insertion of the serine proteinase precursor NS2B-NS3(Pro) of dengue virus type 2 is required for efficient in vitro processing and is mediated through the hydrophobic regions of NS2B
-
Clum S., Ebner K.E., and Padmanabhan R. Cotranslational membrane insertion of the serine proteinase precursor NS2B-NS3(Pro) of dengue virus type 2 is required for efficient in vitro processing and is mediated through the hydrophobic regions of NS2B. J. Biol. Chem. 272 (1997) 30715-30723
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30715-30723
-
-
Clum, S.1
Ebner, K.E.2
Padmanabhan, R.3
-
34
-
-
0036849786
-
Implications of high RNA virus mutation rates: lethal mutagenesis and the antiviral drug ribavirin
-
Crotty S., and Andino R. Implications of high RNA virus mutation rates: lethal mutagenesis and the antiviral drug ribavirin. Microbes Infect. 4 (2002) 1301-1307
-
(2002)
Microbes Infect.
, vol.4
, pp. 1301-1307
-
-
Crotty, S.1
Andino, R.2
-
35
-
-
0035811016
-
RNA virus error catastrophe: direct molecular test by using ribavirin
-
Crotty S., Cameron C.E., and Andino R. RNA virus error catastrophe: direct molecular test by using ribavirin. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 6895-6900
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 6895-6900
-
-
Crotty, S.1
Cameron, C.E.2
Andino, R.3
-
36
-
-
0036182633
-
Ribavirin's antiviral mechanism of action: lethal mutagenesis?
-
Crotty S., Cameron C., and Andino R. Ribavirin's antiviral mechanism of action: lethal mutagenesis?. J. Mol. Med. 80 (2002) 86-95
-
(2002)
J. Mol. Med.
, vol.80
, pp. 86-95
-
-
Crotty, S.1
Cameron, C.2
Andino, R.3
-
37
-
-
34247092052
-
Characterization of a replication-competent, integrase-defective human immunodeficiency virus (HIV)/simian virus 40 chimera as a powerful tool for the discovery and validation of HIV integrase inhibitors
-
Daelemans D., Lu R., De Clercq E., and Engelman A. Characterization of a replication-competent, integrase-defective human immunodeficiency virus (HIV)/simian virus 40 chimera as a powerful tool for the discovery and validation of HIV integrase inhibitors. J. Virol. 81 (2007) 4381-4385
-
(2007)
J. Virol.
, vol.81
, pp. 4381-4385
-
-
Daelemans, D.1
Lu, R.2
De Clercq, E.3
Engelman, A.4
-
38
-
-
35348822495
-
Interaction between the cellular protein eEF1A and the 3'-terminal stem-loop of West Nile virus genomic RNA facilitates viral minus-strand RNA synthesis
-
Davis W.G., Blackwell J.L., Shi P.Y., and Brinton M.A. Interaction between the cellular protein eEF1A and the 3'-terminal stem-loop of West Nile virus genomic RNA facilitates viral minus-strand RNA synthesis. J Virol. 81 (2007) 10172-10187
-
(2007)
J Virol.
, vol.81
, pp. 10172-10187
-
-
Davis, W.G.1
Blackwell, J.L.2
Shi, P.Y.3
Brinton, M.A.4
-
39
-
-
33750527761
-
Discovery of novel, highly potent and selective beta-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles
-
DeMarco S.J., Henze H., Lederer A., Moehle K., Mukherjee R., Romagnoli B., Robinson J.A., Brianza F., Gombert F.O., Lociuro S., Ludin C., Vrijbloed J.W., Zumbrunn J., Obrecht J.P., Obrecht D., Brondani V., Hamy F., and Klimkait T. Discovery of novel, highly potent and selective beta-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles. Bioorg. Med. Chem. 14 (2006) 8396-8404
-
(2006)
Bioorg. Med. Chem.
, vol.14
, pp. 8396-8404
-
-
DeMarco, S.J.1
Henze, H.2
Lederer, A.3
Moehle, K.4
Mukherjee, R.5
Romagnoli, B.6
Robinson, J.A.7
Brianza, F.8
Gombert, F.O.9
Lociuro, S.10
Ludin, C.11
Vrijbloed, J.W.12
Zumbrunn, J.13
Obrecht, J.P.14
Obrecht, D.15
Brondani, V.16
Hamy, F.17
Klimkait, T.18
-
40
-
-
0036061536
-
Translation elongation factor-1alpha, La, and PTB interact with the 3' untranslated region of dengue 4 virus RNA
-
De Nova-Ocampo M., Villegas-Sepulveda N., and del Angel R.M. Translation elongation factor-1alpha, La, and PTB interact with the 3' untranslated region of dengue 4 virus RNA. Virology 295 (2002) 337-347
-
(2002)
Virology
, vol.295
, pp. 337-347
-
-
De Nova-Ocampo, M.1
Villegas-Sepulveda, N.2
del Angel, R.M.3
-
41
-
-
34247564968
-
Distinct RNA elements confer specificity to flavivirus RNA cap methylation events
-
Dong H.P., Ray D., Ren S.P., Zhang B., Puig-Basagoiti F., Takagi Y., Ho C.K., Li H.M., and Shi P.Y. Distinct RNA elements confer specificity to flavivirus RNA cap methylation events. J. Virol. 81 (2007) 4412-4421
-
(2007)
J. Virol.
, vol.81
, pp. 4412-4421
-
-
Dong, H.P.1
Ray, D.2
Ren, S.P.3
Zhang, B.4
Puig-Basagoiti, F.5
Takagi, Y.6
Ho, C.K.7
Li, H.M.8
Shi, P.Y.9
-
42
-
-
50049109958
-
Flavivirus methyltransferase: a novel antiviral target
-
Dong H., Zhang B., and Shi P.-Y. Flavivirus methyltransferase: a novel antiviral target. Antiviral Res. 80 1 (2008) 1-10
-
(2008)
Antiviral Res.
, vol.80
, Issue.1
, pp. 1-10
-
-
Dong, H.1
Zhang, B.2
Shi, P.-Y.3
-
43
-
-
0037013858
-
An RNA cap (nucleoside-2′-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
-
Egloff M.P., Benarroch D., Selisko B., Romette J.L., and Canard B. An RNA cap (nucleoside-2′-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization. EMBO J. 21 (2002) 2757-2768
-
(2002)
EMBO J.
, vol.21
, pp. 2757-2768
-
-
Egloff, M.P.1
Benarroch, D.2
Selisko, B.3
Romette, J.L.4
Canard, B.5
-
44
-
-
34548148632
-
Structural and functional analysis of methylation and 5′-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
-
Egloff M.P., Decroly E., Malet H., Selisko B., Benarroch D., Ferron F., and Canard B. Structural and functional analysis of methylation and 5′-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5. J. Mol. Biol. 372 (2007) 723-736
-
(2007)
J. Mol. Biol.
, vol.372
, pp. 723-736
-
-
Egloff, M.P.1
Decroly, E.2
Malet, H.3
Selisko, B.4
Benarroch, D.5
Ferron, F.6
Canard, B.7
-
45
-
-
34547456097
-
Interaction of TIA-1/TIAR with West Nile and dengue virus products in infected cells interferes with stress granule formation and processing body assembly
-
Emara M.M., and Brinton M.A. Interaction of TIA-1/TIAR with West Nile and dengue virus products in infected cells interferes with stress granule formation and processing body assembly. Proc Natl Acad Sci U. S. A. 104 (2007) 9041-9046
-
(2007)
Proc Natl Acad Sci U. S. A.
, vol.104
, pp. 9041-9046
-
-
Emara, M.M.1
Brinton, M.A.2
-
46
-
-
33745025763
-
Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus
-
Erbel P., Schiering N., D'Arcy A., Renatus M., Kroemer M., Lim S.P., Yin Z., Keller T.H., Vasudevan S.G., and Hommel U. Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus. Nat. Struct. Mol. Biol. 13 (2006) 372-373
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 372-373
-
-
Erbel, P.1
Schiering, N.2
D'Arcy, A.3
Renatus, M.4
Kroemer, M.5
Lim, S.P.6
Yin, Z.7
Keller, T.H.8
Vasudevan, S.G.9
Hommel, U.10
-
47
-
-
0025864149
-
Both nonstructural proteins NS2b and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins
-
Falgout B., Pethel M., Zhang Y.M., and Lai C.J. Both nonstructural proteins NS2b and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins. J. Virol. 65 (1991) 2467-2475
-
(1991)
J. Virol.
, vol.65
, pp. 2467-2475
-
-
Falgout, B.1
Pethel, M.2
Zhang, Y.M.3
Lai, C.J.4
-
48
-
-
0027499688
-
Deletion analysis of dengue virus type 4 nonstructural protein NS2B: identification of a domain required for NS2B-NS3 protease activity
-
Falgout B., Miller R.H., and Lai C.-J. Deletion analysis of dengue virus type 4 nonstructural protein NS2B: identification of a domain required for NS2B-NS3 protease activity. J. Virol. 67 (1993) 2034-2042
-
(1993)
J. Virol.
, vol.67
, pp. 2034-2042
-
-
Falgout, B.1
Miller, R.H.2
Lai, C.-J.3
-
49
-
-
0141758201
-
Helicases as antiviral drug targets
-
Frick D.N. Helicases as antiviral drug targets. Drug News Perspect. 16 (2003) 355-362
-
(2003)
Drug News Perspect.
, vol.16
, pp. 355-362
-
-
Frick, D.N.1
-
50
-
-
33846456636
-
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
-
Frick D.N. The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target. Curr. Issues Mol. Biol. 9 (2007) 1-20
-
(2007)
Curr. Issues Mol. Biol.
, vol.9
, pp. 1-20
-
-
Frick, D.N.1
-
51
-
-
1842861928
-
La protein binds to NS5 and NS3 and to the 5' and 3' ends of Dengue 4 virus RNA
-
Garcia-Montalvo B.M., Medina F., and del Angel R.M. La protein binds to NS5 and NS3 and to the 5' and 3' ends of Dengue 4 virus RNA. Virus Res. 102 (2004) 141-150
-
(2004)
Virus Res.
, vol.102
, pp. 141-150
-
-
Garcia-Montalvo, B.M.1
Medina, F.2
del Angel, R.M.3
-
52
-
-
0024341494
-
N-terminal domains of putative helicases of flavi- and pestiviruses may be serine proteases
-
Gorbalenya A.E., Donchenko A.P., Koonin E.V., and Blinov V.M. N-terminal domains of putative helicases of flavi- and pestiviruses may be serine proteases. Nucleic Acids Res. 17 (1989) 3889-3897
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 3889-3897
-
-
Gorbalenya, A.E.1
Donchenko, A.P.2
Koonin, E.V.3
Blinov, V.M.4
-
53
-
-
33846106926
-
Substrate specificity of recombinant dengue 2 virus NS2B-NS3 protease: influence of natural and unnatural basic amino acids on hydrolysis of synthetic fluorescent substrates
-
Gouvea I.E., Izidoro M.A., Judice W.A., Cezari M.H., Caliendo G., Santagada V., dos Santos C.N., Queiroz M.H., Juliano M.A., Young P.R., Fairlie D.P., and Juliano L. Substrate specificity of recombinant dengue 2 virus NS2B-NS3 protease: influence of natural and unnatural basic amino acids on hydrolysis of synthetic fluorescent substrates. Arch. Biochem. Biophys. 457 (2007) 187-196
-
(2007)
Arch. Biochem. Biophys.
, vol.457
, pp. 187-196
-
-
Gouvea, I.E.1
Izidoro, M.A.2
Judice, W.A.3
Cezari, M.H.4
Caliendo, G.5
Santagada, V.6
dos Santos, C.N.7
Queiroz, M.H.8
Juliano, M.A.9
Young, P.R.10
Fairlie, D.P.11
Juliano, L.12
-
54
-
-
35148825918
-
Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue
-
Graci J.D., Harki D.A., Korneeva V.S., Edathil J.P., Too K., Franco D., Smidansky E.D., Paul A.V., Peterson B.R., Brown D.M., Loakes D., and Cameron C.E. Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue. J. Virol. 81 (2007) 11256-11266
-
(2007)
J. Virol.
, vol.81
, pp. 11256-11266
-
-
Graci, J.D.1
Harki, D.A.2
Korneeva, V.S.3
Edathil, J.P.4
Too, K.5
Franco, D.6
Smidansky, E.D.7
Paul, A.V.8
Peterson, B.R.9
Brown, D.M.10
Loakes, D.11
Cameron, C.E.12
-
55
-
-
0023031091
-
Characterization of West Nile virus RNA-dependent RNA polymerase and cellular terminal adenylyl and uridylyl transferases in cell-free extracts
-
Grun J.B., and Brinton M.A. Characterization of West Nile virus RNA-dependent RNA polymerase and cellular terminal adenylyl and uridylyl transferases in cell-free extracts. J. Virol. 60 (1986) 1113-1124
-
(1986)
J. Virol.
, vol.60
, pp. 1113-1124
-
-
Grun, J.B.1
Brinton, M.A.2
-
56
-
-
0023031091
-
Characterization of West Nile virus RNA-dependent RNA polymerase and cellular terminal adenylyl and uridylyl transferases in cell-free extracts
-
Grun J.B., and Brinton M.A. Characterization of West Nile virus RNA-dependent RNA polymerase and cellular terminal adenylyl and uridylyl transferases in cell-free extracts. J. Virol. 60 (1986) 1103-1124
-
(1986)
J. Virol.
, vol.60
, pp. 1103-1124
-
-
Grun, J.B.1
Brinton, M.A.2
-
57
-
-
35348925573
-
Flaviviruses
-
Knipe D.M., and Howley P.M. (Eds), Lippincott William & Wilkins, Philadelphia, PA
-
Gubler D., Kuno G., and Markoff L. Flaviviruses. In: Knipe D.M., and Howley P.M. (Eds). Fields Virology. 5th ed. 1 (2007), Lippincott William & Wilkins, Philadelphia, PA 1153-1253
-
(2007)
Fields Virology. 5th ed.
, vol.1
, pp. 1153-1253
-
-
Gubler, D.1
Kuno, G.2
Markoff, L.3
-
58
-
-
0035150449
-
Expression and purification of enzymatically active recombinant RNA-dependent RNA polymerase (NS5) of the flavivirus Kunjin
-
Guyatt K.J., Westaway E.G., and Khromykh A.A. Expression and purification of enzymatically active recombinant RNA-dependent RNA polymerase (NS5) of the flavivirus Kunjin. J. Virol. Methods 92 (2001) 37-44
-
(2001)
J. Virol. Methods
, vol.92
, pp. 37-44
-
-
Guyatt, K.J.1
Westaway, E.G.2
Khromykh, A.A.3
-
59
-
-
40749102386
-
Animal models of highly pathogenic RNA viral infections: encephalitis viruses
-
Holbrook M.R., and Gowen B.B. Animal models of highly pathogenic RNA viral infections: encephalitis viruses. Antiviral Res. 78 (2008) 69-78
-
(2008)
Antiviral Res.
, vol.78
, pp. 69-78
-
-
Holbrook, M.R.1
Gowen, B.B.2
-
60
-
-
42149130312
-
Future directions in therapy for chronic hepatitis C
-
Jensen D.M., and Ascione A. Future directions in therapy for chronic hepatitis C. Antiviral Ther. 13 Suppl. 1 (2008) 31-36
-
(2008)
Antiviral Ther.
, vol.13
, Issue.SUPPL. 1
, pp. 31-36
-
-
Jensen, D.M.1
Ascione, A.2
-
61
-
-
0035061425
-
A small region of the dengue virus-encoded RNA-dependent RNA polymerase, NS5, confers interaction with both the nuclear transport receptor importin-beta and the viral helicase, NS3
-
Johansson M., Brooks A.J., Jans D.A., and Vasudevan S.G. A small region of the dengue virus-encoded RNA-dependent RNA polymerase, NS5, confers interaction with both the nuclear transport receptor importin-beta and the viral helicase, NS3. J. Gen. Virol. 82 (2001) 735-745
-
(2001)
J. Gen. Virol.
, vol.82
, pp. 735-745
-
-
Johansson, M.1
Brooks, A.J.2
Jans, D.A.3
Vasudevan, S.G.4
-
62
-
-
0037997042
-
Acyl sulfonamides as potent protease inhibitors of the hepatitis C virus full-length NS3 (protease-helicase/NTPase): a comparative study of different C-terminals
-
Johansson A., Poliakov A., Akerblom E., Wiklund K., Lindeberg G., Winiwarter S., Danielson U.H., Samuelsson B., and Hallberg A. Acyl sulfonamides as potent protease inhibitors of the hepatitis C virus full-length NS3 (protease-helicase/NTPase): a comparative study of different C-terminals. Bioorg. Med. Chem. 11 (2003) 2551-2568
-
(2003)
Bioorg. Med. Chem.
, vol.11
, pp. 2551-2568
-
-
Johansson, A.1
Poliakov, A.2
Akerblom, E.3
Wiklund, K.4
Lindeberg, G.5
Winiwarter, S.6
Danielson, U.H.7
Samuelsson, B.8
Hallberg, A.9
-
63
-
-
38049053633
-
HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus
-
Johnston P.A., Phillips J., Shun T.Y., Shinde S., Lazo J.S., Huryn D.M., Myers M.C., Ratnikov B.I., Smith J.W., Su Y., Dahl R., Cosford N.D.P., Shiryaev S.A., and Strongin A.Y. HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus. Assay Drug Dev. Technol. 5 (2007) 737-750
-
(2007)
Assay Drug Dev. Technol.
, vol.5
, pp. 737-750
-
-
Johnston, P.A.1
Phillips, J.2
Shun, T.Y.3
Shinde, S.4
Lazo, J.S.5
Huryn, D.M.6
Myers, M.C.7
Ratnikov, B.I.8
Smith, J.W.9
Su, Y.10
Dahl, R.11
Cosford, N.D.P.12
Shiryaev, S.A.13
Strongin, A.Y.14
-
64
-
-
0038617775
-
Flavivirus capsid is a dimeric alpha-helical protein
-
Jones C.T., Ma L.X., Burgner J.W., Groesch T.D., Post C.B., and Kuhn R.J. Flavivirus capsid is a dimeric alpha-helical protein. J. Virol. 77 (2003) 7143-7149
-
(2003)
J. Virol.
, vol.77
, pp. 7143-7149
-
-
Jones, C.T.1
Ma, L.X.2
Burgner, J.W.3
Groesch, T.D.4
Post, C.B.5
Kuhn, R.J.6
-
65
-
-
33646183540
-
The 2′,5′-oligoadenylate synthetase 1b is a potent inhibitor of West Nile virus replication inside infected cells
-
Kajaste-Rudnitski A., Mashimo T., Frenkiel M.P., Guenet J.L., Lucas M., and Despres P. The 2′,5′-oligoadenylate synthetase 1b is a potent inhibitor of West Nile virus replication inside infected cells. J. Biol. Chem. 281 (2006) 4624-4637
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 4624-4637
-
-
Kajaste-Rudnitski, A.1
Mashimo, T.2
Frenkiel, M.P.3
Guenet, J.L.4
Lucas, M.5
Despres, P.6
-
66
-
-
33745092046
-
Peptide, peptidomimetic and small-molecule drug discovery targeting HIV-1 host-cell attachment and entry through gp120, gp41, CCR5 and CXCR4
-
Kazmierski W.M., Kenakin T.P., and Gudmundsson K.S. Peptide, peptidomimetic and small-molecule drug discovery targeting HIV-1 host-cell attachment and entry through gp120, gp41, CCR5 and CXCR4. Chem. Biol. Drug Des. 67 (2006) 13-26
-
(2006)
Chem. Biol. Drug Des.
, vol.67
, pp. 13-26
-
-
Kazmierski, W.M.1
Kenakin, T.P.2
Gudmundsson, K.S.3
-
67
-
-
0029684652
-
RNA binding properties of core protein of the flavivirus Kunjin
-
Khromykh A.A., and Westaway E.G. RNA binding properties of core protein of the flavivirus Kunjin. Arch. Virol. 141 (1996) 685-699
-
(1996)
Arch. Virol.
, vol.141
, pp. 685-699
-
-
Khromykh, A.A.1
Westaway, E.G.2
-
68
-
-
0036004555
-
In vitro determination of dengue virus type 2 NS2B-NS3 protease activity with fluorescent peptide substrates
-
Khumthong R., Angsuthanasombat C., Panyim S., and Katzenmeier G. In vitro determination of dengue virus type 2 NS2B-NS3 protease activity with fluorescent peptide substrates. J. Biochem. Mol. Biol. 35 (2002) 206-212
-
(2002)
J. Biochem. Mol. Biol.
, vol.35
, pp. 206-212
-
-
Khumthong, R.1
Angsuthanasombat, C.2
Panyim, S.3
Katzenmeier, G.4
-
69
-
-
0037252890
-
Steady-state cleavage kinetics for dengue virus type 2 ns2b-ns3(pro) serine protease with synthetic peptides
-
Khumthong R., Niyomrattanakit P., Chanprapaph S., Angsuthanasombat C., Panyim S., and Katzenmeier G. Steady-state cleavage kinetics for dengue virus type 2 ns2b-ns3(pro) serine protease with synthetic peptides. Protein Pept. Lett. 10 (2003) 19-26
-
(2003)
Protein Pept. Lett.
, vol.10
, pp. 19-26
-
-
Khumthong, R.1
Niyomrattanakit, P.2
Chanprapaph, S.3
Angsuthanasombat, C.4
Panyim, S.5
Katzenmeier, G.6
-
70
-
-
3242656261
-
Isolation of capsid protein dimers from the tick-borne encephalitis flavivirus and in vitro assembly of capsid-like particles
-
Kiermayr S., Kofler R.M., Mandl C.W., Messner P., and Heinz F.X. Isolation of capsid protein dimers from the tick-borne encephalitis flavivirus and in vitro assembly of capsid-like particles. J. Virol. 78 (2004) 8078-8084
-
(2004)
J. Virol.
, vol.78
, pp. 8078-8084
-
-
Kiermayr, S.1
Kofler, R.M.2
Mandl, C.W.3
Messner, P.4
Heinz, F.X.5
-
71
-
-
33750451238
-
Peptide inhibitors of West Nile NS3 protease: SAR study of tetrapeptide aldehyde inhibitors
-
Knox J.E., Ma N.L., Yin Z., Patel S.J., Wang W.L., Chan W.L., Ranga Rao K.R., Wang G., Ngew X., Patel V., Beer D., Lim S.P., Vasudevan S.G., and Keller T.H. Peptide inhibitors of West Nile NS3 protease: SAR study of tetrapeptide aldehyde inhibitors. J. Med. Chem. 49 (2006) 6585-6590
-
(2006)
J. Med. Chem.
, vol.49
, pp. 6585-6590
-
-
Knox, J.E.1
Ma, N.L.2
Yin, Z.3
Patel, S.J.4
Wang, W.L.5
Chan, W.L.6
Ranga Rao, K.R.7
Wang, G.8
Ngew, X.9
Patel, V.10
Beer, D.11
Lim, S.P.12
Vasudevan, S.G.13
Keller, T.H.14
-
72
-
-
34247637615
-
Rab 5 is required for the cellular entry of dengue and West Nile viruses
-
Krishnan M.N., Sukumaran B., Pal U., Agaisse H., Murray J.L., Hodge T.W., and Fikrig E. Rab 5 is required for the cellular entry of dengue and West Nile viruses. J. Virol. 81 (2007) 4881-4885
-
(2007)
J. Virol.
, vol.81
, pp. 4881-4885
-
-
Krishnan, M.N.1
Sukumaran, B.2
Pal, U.3
Agaisse, H.4
Murray, J.L.5
Hodge, T.W.6
Fikrig, E.7
-
73
-
-
53249121029
-
Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target
-
Lescar J., Dahai L., Xu T., Sampath A., Lim S.P., Canard B., and Vasudevan S.G. Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target. Antiviral Res. 80 (2008) 94-101
-
(2008)
Antiviral Res.
, vol.80
, pp. 94-101
-
-
Lescar, J.1
Dahai, L.2
Xu, T.3
Sampath, A.4
Lim, S.P.5
Canard, B.6
Vasudevan, S.G.7
-
74
-
-
0035824539
-
Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors
-
Leung D., Schroder K., White H., Fang N.X., Stoermer M.J., Abbenante G., Martin J.L., Young P.R., and Fairlie D.P. Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors. J. Biol. Chem. 276 (2001) 45762-45771
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45762-45771
-
-
Leung, D.1
Schroder, K.2
White, H.3
Fang, N.X.4
Stoermer, M.J.5
Abbenante, G.6
Martin, J.L.7
Young, P.R.8
Fairlie, D.P.9
-
75
-
-
43249124059
-
Role of nonstructural protein NS2A in flavivirus assembly
-
Leung J.Y., Pijlman G.P., Kondratieva N., Hyde J., Mackenzie J.M., and Khromykh A.A. Role of nonstructural protein NS2A in flavivirus assembly. J. Virol. 82 (2008) 4731-4741
-
(2008)
J. Virol.
, vol.82
, pp. 4731-4741
-
-
Leung, J.Y.1
Pijlman, G.P.2
Kondratieva, N.3
Hyde, J.4
Mackenzie, J.M.5
Khromykh, A.A.6
-
76
-
-
33645102511
-
The anti-yellow fever virus activity of ribavirin is independent of error-prone replication
-
Leyssen P., De Clercq E., and Neyts J. The anti-yellow fever virus activity of ribavirin is independent of error-prone replication. Mol. Pharmacol. 69 (2006) 1461-1467
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 1461-1467
-
-
Leyssen, P.1
De Clercq, E.2
Neyts, J.3
-
77
-
-
40849126566
-
Molecular strategies to inhibit the replication of RNA viruses
-
Leyssen P., De Clercq E., and Neyts J. Molecular strategies to inhibit the replication of RNA viruses. Antiviral Res. 78 (2008) 9-25
-
(2008)
Antiviral Res.
, vol.78
, pp. 9-25
-
-
Leyssen, P.1
De Clercq, E.2
Neyts, J.3
-
78
-
-
0032976077
-
The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids
-
Li H., Clum S.R., You S., Ebner K.E., and Padmanabhan R. The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids. J. Virol. 73 (1999) 3108-3116
-
(1999)
J. Virol.
, vol.73
, pp. 3108-3116
-
-
Li, H.1
Clum, S.R.2
You, S.3
Ebner, K.E.4
Padmanabhan, R.5
-
79
-
-
0036888883
-
Cell proteins TIA-1 and TIAR interact with the 3' stem-loop of the West Nile virus complementary minus-strand RNA and facilitate virus replication
-
Li W., Li Y., Kedersha N., Anderson P., Emara M., Swiderek K.M., Moreno G.T., and Brinton M.A. Cell proteins TIA-1 and TIAR interact with the 3' stem-loop of the West Nile virus complementary minus-strand RNA and facilitate virus replication. J Virol. 76 (2002) 11989-12000
-
(2002)
J Virol.
, vol.76
, pp. 11989-12000
-
-
Li, W.1
Li, Y.2
Kedersha, N.3
Anderson, P.4
Emara, M.5
Swiderek, K.M.6
Moreno, G.T.7
Brinton, M.A.8
-
80
-
-
23344446921
-
Functional profiling of recombinant NS3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries
-
Li J., Lim S.P., Beer D., Patel V., Wen D.Y., Tumanut C., Tully D.C., Williams J.A., Jiricek J., Priestle J.P., Harris J.L., and Vasudevan S.G. Functional profiling of recombinant NS3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries. J. Biol. Chem. 280 (2005) 28766-28774
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28766-28774
-
-
Li, J.1
Lim, S.P.2
Beer, D.3
Patel, V.4
Wen, D.Y.5
Tumanut, C.6
Tully, D.C.7
Williams, J.A.8
Jiricek, J.9
Priestle, J.P.10
Harris, J.L.11
Vasudevan, S.G.12
-
81
-
-
41349112506
-
The flavivirus precursor membrane-envelope protein complex: structure and maturation
-
Li L., Lok S.M., Yu I.M., Zhang Y., Kuhn R.J., Chen J., and Rossmann M.G. The flavivirus precursor membrane-envelope protein complex: structure and maturation. Science 319 (2008) 1830-1834
-
(2008)
Science
, vol.319
, pp. 1830-1834
-
-
Li, L.1
Lok, S.M.2
Yu, I.M.3
Zhang, Y.4
Kuhn, R.J.5
Chen, J.6
Rossmann, M.G.7
-
82
-
-
0030774240
-
Trans-complementation of yellow fever virus NS1 reveals a role in early RNA replication
-
Lindenbach B.D., and Rice C.M. Trans-complementation of yellow fever virus NS1 reveals a role in early RNA replication. J. Virol. 71 (1997) 9608-9617
-
(1997)
J. Virol.
, vol.71
, pp. 9608-9617
-
-
Lindenbach, B.D.1
Rice, C.M.2
-
83
-
-
0011115399
-
-
Lippincott William & Wilkins, Philadelphia, USA
-
Lindenbach B.D., Thiel H.J., and Rice C.M. Flaviviridae: The Viruses and Their Replication (2007), Lippincott William & Wilkins, Philadelphia, USA
-
(2007)
Flaviviridae: The Viruses and Their Replication
-
-
Lindenbach, B.D.1
Thiel, H.J.2
Rice, C.M.3
-
84
-
-
47949084830
-
Review: hepatitis C protease and polymerase inhibitors in development
-
Liu-Young G., and Kozal M.J. Review: hepatitis C protease and polymerase inhibitors in development. AIDS Patient Care STDS 22 6 (2008) 449-457
-
(2008)
AIDS Patient Care STDS
, vol.22
, Issue.6
, pp. 449-457
-
-
Liu-Young, G.1
Kozal, M.J.2
-
85
-
-
26444479397
-
Inhibitors of respiratory syncytial virus replication target cotranscriptional mRNA guanylylation by viral RNA-dependent RNA polymerase
-
Liuzzi M., Mason S.W., Cartier M., Lawetz C., McCollum R.S., Dansereau N., Bolger G., Lapeyre N., Gaudette Y., Lagace L., Massariol M.J., Do F., Whitehead P., Lamarre L., Scouten E., Bordeleau J., Landry S., Rancourt J., Fazal G., and Simoneau B. Inhibitors of respiratory syncytial virus replication target cotranscriptional mRNA guanylylation by viral RNA-dependent RNA polymerase. J. Virol. 79 (2005) 13105-13115
-
(2005)
J. Virol.
, vol.79
, pp. 13105-13115
-
-
Liuzzi, M.1
Mason, S.W.2
Cartier, M.3
Lawetz, C.4
McCollum, R.S.5
Dansereau, N.6
Bolger, G.7
Lapeyre, N.8
Gaudette, Y.9
Lagace, L.10
Massariol, M.J.11
Do, F.12
Whitehead, P.13
Lamarre, L.14
Scouten, E.15
Bordeleau, J.16
Landry, S.17
Rancourt, J.18
Fazal, G.19
Simoneau, B.20
more..
-
86
-
-
34547578902
-
Yellow fever virus NS3 protease: peptide-inhibition studies
-
Lohr K., Knox J.E., Phong W.Y., Ma N.L., Yin Z., Sampath A., Patel S.J., Wang W.L., Chan W.L., Rao K.R., Wang G., Vasudevan S.G., Keller T.H., and Lim S.P. Yellow fever virus NS3 protease: peptide-inhibition studies. J. Gen. Virol. 88 (2007) 2223-2227
-
(2007)
J. Gen. Virol.
, vol.88
, pp. 2223-2227
-
-
Lohr, K.1
Knox, J.E.2
Phong, W.Y.3
Ma, N.L.4
Yin, Z.5
Sampath, A.6
Patel, S.J.7
Wang, W.L.8
Chan, W.L.9
Rao, K.R.10
Wang, G.11
Vasudevan, S.G.12
Keller, T.H.13
Lim, S.P.14
-
87
-
-
21244462832
-
Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals
-
Lozach P.Y., Burleigh L., Staropoli I., Navarro-Sanchez E., Harriague J., Virelizier J.L., Rey F.A., Despres P., Arenzana-Seisdedos F., and Amara A. Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals. J. Biol. Chem. 280 (2005) 23698-23708
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 23698-23708
-
-
Lozach, P.Y.1
Burleigh, L.2
Staropoli, I.3
Navarro-Sanchez, E.4
Harriague, J.5
Virelizier, J.L.6
Rey, F.A.7
Despres, P.8
Arenzana-Seisdedos, F.9
Amara, A.10
-
88
-
-
37349023165
-
Crystal structure of the NS3 protease-helicase from dengue virus
-
Luo D., Xu T., Hunke C., Gruber G., Vasudevan S.G., and Lescar J. Crystal structure of the NS3 protease-helicase from dengue virus. J. Virol. 82 (2008) 173-183
-
(2008)
J. Virol.
, vol.82
, pp. 173-183
-
-
Luo, D.1
Xu, T.2
Hunke, C.3
Gruber, G.4
Vasudevan, S.G.5
Lescar, J.6
-
89
-
-
35348920605
-
Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2′ O)-methyltransferase
-
Luzhkov V.B., Selisko B., Nordqvist A., Peyrane F., Decroly E., Alvarez K., Karlen A., Canard B., and Aqvist J. Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2′ O)-methyltransferase. Bioorg. Med. Chem. 15 (2007) 7795-7802
-
(2007)
Bioorg. Med. Chem.
, vol.15
, pp. 7795-7802
-
-
Luzhkov, V.B.1
Selisko, B.2
Nordqvist, A.3
Peyrane, F.4
Decroly, E.5
Alvarez, K.6
Karlen, A.7
Canard, B.8
Aqvist, J.9
-
90
-
-
1542723492
-
Solution structure of dengue virus capsid protein reveals another fold
-
Ma L.X., Jones C.T., Groesch T.D., Kuhn R.J., and Post C.B. Solution structure of dengue virus capsid protein reveals another fold. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 3414-3419
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 3414-3419
-
-
Ma, L.X.1
Jones, C.T.2
Groesch, T.D.3
Kuhn, R.J.4
Post, C.B.5
-
91
-
-
26944495290
-
Wrapping things up about virus RNA replication
-
Mackenzie J. Wrapping things up about virus RNA replication. Traffic 6 (2005) 967-977
-
(2005)
Traffic
, vol.6
, pp. 967-977
-
-
Mackenzie, J.1
-
92
-
-
0034767341
-
Assembly and maturation of the flavivirus Kunjin virus appear to occur in the rough endoplasmic reticulum and along the secretory pathway, respectively
-
MacKenzie J.M., and Westaway E.G. Assembly and maturation of the flavivirus Kunjin virus appear to occur in the rough endoplasmic reticulum and along the secretory pathway, respectively. J. Virol. 75 (2001) 10787-10799
-
(2001)
J. Virol.
, vol.75
, pp. 10787-10799
-
-
MacKenzie, J.M.1
Westaway, E.G.2
-
93
-
-
0032486487
-
Subcellular localization and some biochemical properties of the flavivirus Kunjin nonstructural proteins NS2A and NS4A
-
Mackenzie J.M., Khromykh A.A., Jones M.K., and Westaway E.G. Subcellular localization and some biochemical properties of the flavivirus Kunjin nonstructural proteins NS2A and NS4A. Virology 245 (1998) 203-215
-
(1998)
Virology
, vol.245
, pp. 203-215
-
-
Mackenzie, J.M.1
Khromykh, A.A.2
Jones, M.K.3
Westaway, E.G.4
-
94
-
-
10944252079
-
Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses
-
Mackenzie J.S., Gubler D.J., and Petersen L.R. Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses. Nat. Med. 10 (2004) S98-S109
-
(2004)
Nat. Med.
, vol.10
-
-
Mackenzie, J.S.1
Gubler, D.J.2
Petersen, L.R.3
-
95
-
-
22244485047
-
Specific targeting of hepatitis C virus NS3 RNA helicase; discovery of the potent and selective competitive nucleotide-mimicking inhibitor QU663
-
Maga G., Gemma S., Fattorusso C., Locatelli G.A., Butini S., Persico M., Kukreja G., Romano M.P., Chiasserini L., Savini L., Novellino E., Nacci V., Spadari S., and Campiani G. Specific targeting of hepatitis C virus NS3 RNA helicase; discovery of the potent and selective competitive nucleotide-mimicking inhibitor QU663. Biochemistry 44 (2005) 9637-9644
-
(2005)
Biochemistry
, vol.44
, pp. 9637-9644
-
-
Maga, G.1
Gemma, S.2
Fattorusso, C.3
Locatelli, G.A.4
Butini, S.5
Persico, M.6
Kukreja, G.7
Romano, M.P.8
Chiasserini, L.9
Savini, L.10
Novellino, E.11
Nacci, V.12
Spadari, S.13
Campiani, G.14
-
96
-
-
34249845069
-
Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
-
Malet H., Egloff M.P., Selisko B., Butcher R.E., Wright P.J., Roberts M., Gruez A., Sulzenbacher G., Vonrhein C., Bricogne G., Mackenzie J.M., Khromykh A.A., Davidson A.D., and Canard B. Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5. J. Biol. Chem. 282 (2007) 10678-10689
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 10678-10689
-
-
Malet, H.1
Egloff, M.P.2
Selisko, B.3
Butcher, R.E.4
Wright, P.J.5
Roberts, M.6
Gruez, A.7
Sulzenbacher, G.8
Vonrhein, C.9
Bricogne, G.10
Mackenzie, J.M.11
Khromykh, A.A.12
Davidson, A.D.13
Canard, B.14
-
97
-
-
50249147367
-
The flavivirus polymerase as a target for drug discovery
-
Malet H., Massé N., Selisko B., Romette J.-L., Alvarez K., Guillemot J.C., Hughes H., Yap T.H., Vasudevan S., Lescar J., and Canard B. The flavivirus polymerase as a target for drug discovery. Antiviral Res. 80 1 (2008) 23-35
-
(2008)
Antiviral Res.
, vol.80
, Issue.1
, pp. 23-35
-
-
Malet, H.1
Massé, N.2
Selisko, B.3
Romette, J.-L.4
Alvarez, K.5
Guillemot, J.C.6
Hughes, H.7
Yap, T.H.8
Vasudevan, S.9
Lescar, J.10
Canard, B.11
-
98
-
-
0033022782
-
Infection of primary cultures of human Kupffer cells by dengue virus: no viral progeny synthesis, but cytokine production is evident
-
Marianneau P., Steffan A.M., Royer C., Drouet M.T., Jaeck D., Kirn A., and Deubel V. Infection of primary cultures of human Kupffer cells by dengue virus: no viral progeny synthesis, but cytokine production is evident. J. Virol. 73 (1999) 5201-5206
-
(1999)
J. Virol.
, vol.73
, pp. 5201-5206
-
-
Marianneau, P.1
Steffan, A.M.2
Royer, C.3
Drouet, M.T.4
Jaeck, D.5
Kirn, A.6
Deubel, V.7
-
99
-
-
34547949535
-
Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein
-
Mastrangelo E., Milani M., Bollati M., Selisko B., Peyrane F., Pandini V., Sorrentino G., Canard B., Konarev P.V., Svergun D.I., de Lamballerie X., Coutard B., Khromykh A.A., and Bolognesi M. Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein. J. Mol. Biol. 372 (2007) 444-455
-
(2007)
J. Mol. Biol.
, vol.372
, pp. 444-455
-
-
Mastrangelo, E.1
Milani, M.2
Bollati, M.3
Selisko, B.4
Peyrane, F.5
Pandini, V.6
Sorrentino, G.7
Canard, B.8
Konarev, P.V.9
Svergun, D.I.10
de Lamballerie, X.11
Coutard, B.12
Khromykh, A.A.13
Bolognesi, M.14
-
100
-
-
0034963947
-
Mutagenesis of the dengue virus type 2 NS3 proteinase and the production of growth-restricted virus
-
Matusan A.E., Kelley P.G., Pryor M.J., Whisstock J.C., Davidson A.D., and Wright P.J. Mutagenesis of the dengue virus type 2 NS3 proteinase and the production of growth-restricted virus. J. Gen. Virol. 82 (2001) 1647-1656
-
(2001)
J. Gen. Virol.
, vol.82
, pp. 1647-1656
-
-
Matusan, A.E.1
Kelley, P.G.2
Pryor, M.J.3
Whisstock, J.C.4
Davidson, A.D.5
Wright, P.J.6
-
101
-
-
0034802008
-
Mutagenesis of the Dengue virus type 2 NS3 protein within and outside helicase motifs: effects on enzyme activity and virus replication
-
Matusan A.E., Pryor M.J., Davidson A.D., and Wright P.J. Mutagenesis of the Dengue virus type 2 NS3 protein within and outside helicase motifs: effects on enzyme activity and virus replication. J. Virol. 75 (2001) 9633-9643
-
(2001)
J. Virol.
, vol.75
, pp. 9633-9643
-
-
Matusan, A.E.1
Pryor, M.J.2
Davidson, A.D.3
Wright, P.J.4
-
102
-
-
35448973002
-
Minocycline inhibits West Nile virus replication and apoptosis in human neuronal cells
-
Michaelis M., Kleinschmidt M.C., Doerr H.W., and Cinatl Jr. J. Minocycline inhibits West Nile virus replication and apoptosis in human neuronal cells. J. Antimicrob. Chemother. 60 5 (2007) 981-986
-
(2007)
J. Antimicrob. Chemother.
, vol.60
, Issue.5
, pp. 981-986
-
-
Michaelis, M.1
Kleinschmidt, M.C.2
Doerr, H.W.3
Cinatl Jr., J.4
-
103
-
-
1542677267
-
Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro
-
Migliaccio G., Tomassini J.E., Carroll S.S., Tomei L., Altamura S., Bhat B., Bartholomew L., Bosserman M.R., Ceccacci A., Colwell L.F., Cortese R., De Francesco R., Eldrup A.B., Getty K.L., Hou X.S., LaFemina R.L., Ludmerer S.W., MacCoss M., McMasters D.R., Stahlhut M.W., Olsen D.B., Hazuda D.J., and Flores O.A. Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro. J. Biol. Chem. 278 (2003) 49164-49170
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 49164-49170
-
-
Migliaccio, G.1
Tomassini, J.E.2
Carroll, S.S.3
Tomei, L.4
Altamura, S.5
Bhat, B.6
Bartholomew, L.7
Bosserman, M.R.8
Ceccacci, A.9
Colwell, L.F.10
Cortese, R.11
De Francesco, R.12
Eldrup, A.B.13
Getty, K.L.14
Hou, X.S.15
LaFemina, R.L.16
Ludmerer, S.W.17
MacCoss, M.18
McMasters, D.R.19
Stahlhut, M.W.20
Olsen, D.B.21
Hazuda, D.J.22
Flores, O.A.23
more..
-
104
-
-
34247848008
-
The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner
-
Miller S., Kastner S., Krijnse-Locker J., Buhler S., and Bartenschlager R. The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner. J. Biol. Chem. 282 (2007) 8873-8882
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 8873-8882
-
-
Miller, S.1
Kastner, S.2
Krijnse-Locker, J.3
Buhler, S.4
Bartenschlager, R.5
-
105
-
-
33846246837
-
Characterization of the West Nile virus protease substrate specificity and inhibitors
-
Mueller N.H., Yon C., Ganesh V.K., and Padmanabhan R. Characterization of the West Nile virus protease substrate specificity and inhibitors. Int. J. Biochem. Cell Biol. 39 (2007) 606-614
-
(2007)
Int. J. Biochem. Cell Biol.
, vol.39
, pp. 606-614
-
-
Mueller, N.H.1
Yon, C.2
Ganesh, V.K.3
Padmanabhan, R.4
-
106
-
-
50949084334
-
Identification and biochemical characterization of small molecule inhibitors of West Nile Virus serine protease by a high throughput screen
-
Mueller N.H., Pattabiraman N., Ansarah-Sobrinho C., Viswanathan P., Pierson T.C., and Padmanabhan R. Identification and biochemical characterization of small molecule inhibitors of West Nile Virus serine protease by a high throughput screen. Antimicrob. Agents Chemother. 52 (2008) 3385-3393
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 3385-3393
-
-
Mueller, N.H.1
Pattabiraman, N.2
Ansarah-Sobrinho, C.3
Viswanathan, P.4
Pierson, T.C.5
Padmanabhan, R.6
-
108
-
-
34147137981
-
Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide
-
Munch J., Standker L., Adermann K., Schulz A., Schindler M., Chinnadurai R., Pohlmann S., Chaipan C., Biet T., Peters T., Meyer B., Wilhelm D., Lu H., Jing W., Jiang S., Forssmann W.G., and Kirchhoff F. Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide. Cell 129 (2007) 263-275
-
(2007)
Cell
, vol.129
, pp. 263-275
-
-
Munch, J.1
Standker, L.2
Adermann, K.3
Schulz, A.4
Schindler, M.5
Chinnadurai, R.6
Pohlmann, S.7
Chaipan, C.8
Biet, T.9
Peters, T.10
Meyer, B.11
Wilhelm, D.12
Lu, H.13
Jing, W.14
Jiang, S.15
Forssmann, W.G.16
Kirchhoff, F.17
-
109
-
-
20744453948
-
Inhibition of alpha/beta interferon signaling by the NS4B protein of flaviviruses
-
Munoz-Jordan J.L., Laurent-Rolle M., Ashour J., Martinez-Sobrido L., Ashok M., Lipkin W.I., and Garcia-Sastre A. Inhibition of alpha/beta interferon signaling by the NS4B protein of flaviviruses. J. Virol. 79 (2005) 8004-8013
-
(2005)
J. Virol.
, vol.79
, pp. 8004-8013
-
-
Munoz-Jordan, J.L.1
Laurent-Rolle, M.2
Ashour, J.3
Martinez-Sobrido, L.4
Ashok, M.5
Lipkin, W.I.6
Garcia-Sastre, A.7
-
110
-
-
0031060332
-
Genetic analysis of the yellow fever virus NS1 protein: identification of a temperature-sensitive mutation which blocks RNA accumulation
-
Muylaert I.R., Galler R., and Rice C.M. Genetic analysis of the yellow fever virus NS1 protein: identification of a temperature-sensitive mutation which blocks RNA accumulation. J. Virol. 71 (1997) 291-298
-
(1997)
J. Virol.
, vol.71
, pp. 291-298
-
-
Muylaert, I.R.1
Galler, R.2
Rice, C.M.3
-
111
-
-
10344248922
-
Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease
-
Nall T.A., Chappell K.J., Stoermer M.J., Fang N.X., Tyndall J.D.A., Young P.R., and Fairlie D.P. Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease. J. Biol. Chem. 279 (2004) 48535-48542
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 48535-48542
-
-
Nall, T.A.1
Chappell, K.J.2
Stoermer, M.J.3
Fang, N.X.4
Tyndall, J.D.A.5
Young, P.R.6
Fairlie, D.P.7
-
112
-
-
35349023246
-
Construction and characterization of a stable subgenomic dengue virus type 2 replicon system for antiviral compound and siRNA testing
-
Ng C.Y., Gu F., Phong W.Y., Chen Y.L., Lim S.P., Davidson A., and Vasudevan S.G. Construction and characterization of a stable subgenomic dengue virus type 2 replicon system for antiviral compound and siRNA testing. Antiviral Res. 76 (2007) 222-231
-
(2007)
Antiviral Res.
, vol.76
, pp. 222-231
-
-
Ng, C.Y.1
Gu, F.2
Phong, W.Y.3
Chen, Y.L.4
Lim, S.P.5
Davidson, A.6
Vasudevan, S.G.7
-
113
-
-
0041707804
-
De novo synthesis of negative-strand RNA by dengue virus RNA-dependent RNA polymerase in vitro: nucleotide, primer, and template parameters
-
Nomaguchi M., Ackermann M., Yon C., You S., and Padmanbhan R. De novo synthesis of negative-strand RNA by dengue virus RNA-dependent RNA polymerase in vitro: nucleotide, primer, and template parameters. J. Virol. 77 (2003) 8831-8842
-
(2003)
J. Virol.
, vol.77
, pp. 8831-8842
-
-
Nomaguchi, M.1
Ackermann, M.2
Yon, C.3
You, S.4
Padmanbhan, R.5
-
114
-
-
1842582777
-
Requirements for West Nile virus (-)- and (+)-strand subgenomic RNA synthesis in vitro by the viral RNA-dependent RNA polymerase expressed in Escherichia coli
-
Nomaguchi M., Teramoto T., Yu L., Markoff L., and Padmanabhan R. Requirements for West Nile virus (-)- and (+)-strand subgenomic RNA synthesis in vitro by the viral RNA-dependent RNA polymerase expressed in Escherichia coli. J. Biol. Chem. 279 (2004) 12141-12151
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 12141-12151
-
-
Nomaguchi, M.1
Teramoto, T.2
Yu, L.3
Markoff, L.4
Padmanabhan, R.5
-
115
-
-
33645966527
-
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase
-
Paeshuyse J., Leyssen P., Mabery E., Boddeker N., Vrancken R., Froeyen M., Ansari I.H., Dutartre H., Rozenski J., Gil L.H., Letellier C., Lanford R., Canard B., Koenen F., Kerkhofs P., Donis R.O., Herdewijn P., Watson J., De Clercq E., Puerstinger G., and Neyts J. A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase. J. Virol. 80 (2006) 149-160
-
(2006)
J. Virol.
, vol.80
, pp. 149-160
-
-
Paeshuyse, J.1
Leyssen, P.2
Mabery, E.3
Boddeker, N.4
Vrancken, R.5
Froeyen, M.6
Ansari, I.H.7
Dutartre, H.8
Rozenski, J.9
Gil, L.H.10
Letellier, C.11
Lanford, R.12
Canard, B.13
Koenen, F.14
Kerkhofs, P.15
Donis, R.O.16
Herdewijn, P.17
Watson, J.18
De Clercq, E.19
Puerstinger, G.20
Neyts, J.21
more..
-
116
-
-
0038278911
-
Mutagenesis versus inhibition in the efficiency of extinction of foot-and-mouth disease virus
-
Pariente N., Airaksinen A., and Domingo E. Mutagenesis versus inhibition in the efficiency of extinction of foot-and-mouth disease virus. J. Virol. 77 (2003) 7131-7138
-
(2003)
J. Virol.
, vol.77
, pp. 7131-7138
-
-
Pariente, N.1
Airaksinen, A.2
Domingo, E.3
-
117
-
-
34249929993
-
Functional requirements of the yellow fever virus capsid protein
-
Patkar C.G., Jones C.T., Chang Y.H., Warrier R., and Kuhn R.J. Functional requirements of the yellow fever virus capsid protein. J. Virol. 81 (2007) 6471-6481
-
(2007)
J. Virol.
, vol.81
, pp. 6471-6481
-
-
Patkar, C.G.1
Jones, C.T.2
Chang, Y.H.3
Warrier, R.4
Kuhn, R.J.5
-
118
-
-
50049120491
-
Closing the door on flaviviruses: entry as a target for antiviral drug design
-
Perera R., Khaliq M., and Kuhn R.J. Closing the door on flaviviruses: entry as a target for antiviral drug design. Antiviral Res. 80 1 (2008) 11-22
-
(2008)
Antiviral Res.
, vol.80
, Issue.1
, pp. 11-22
-
-
Perera, R.1
Khaliq, M.2
Kuhn, R.J.3
-
119
-
-
32844457056
-
A rapid and quantitative assay for measuring antibody-mediated neutralization of West Nile virus infection
-
Pierson T.C., Sanchez M.D., Puffer B.A., Ahmed A.A., Geiss B.J., Valentine L.E., Altamura L.A., Diamond M.S., and Doms R.W. A rapid and quantitative assay for measuring antibody-mediated neutralization of West Nile virus infection. Virology 346 (2006) 53-65
-
(2006)
Virology
, vol.346
, pp. 53-65
-
-
Pierson, T.C.1
Sanchez, M.D.2
Puffer, B.A.3
Ahmed, A.A.4
Geiss, B.J.5
Valentine, L.E.6
Altamura, L.A.7
Diamond, M.S.8
Doms, R.W.9
-
120
-
-
0025033393
-
In vitro processing of dengue virus type 2 nonstructural proteins NS2A, NS2B, and NS3
-
Preugschat F., Yao C.W., and Strauss J.H. In vitro processing of dengue virus type 2 nonstructural proteins NS2A, NS2B, and NS3. J. Virol. 64 (1990) 4364-4374
-
(1990)
J. Virol.
, vol.64
, pp. 4364-4374
-
-
Preugschat, F.1
Yao, C.W.2
Strauss, J.H.3
-
121
-
-
42449111776
-
Structure-based mutagenesis identifies important novel determinants of the NS2B cofactor of the West Nile virus two-component NS2B-NS3 proteinase
-
Radichev I., Shiryaev S.A., Aleshin A.E., Ratnikov B.I., Smith J.W., Liddington R.C., and Strongin A.Y. Structure-based mutagenesis identifies important novel determinants of the NS2B cofactor of the West Nile virus two-component NS2B-NS3 proteinase. J. Gen. Virol. 89 (2008) 636-641
-
(2008)
J. Gen. Virol.
, vol.89
, pp. 636-641
-
-
Radichev, I.1
Shiryaev, S.A.2
Aleshin, A.E.3
Ratnikov, B.I.4
Smith, J.W.5
Liddington, R.C.6
Strongin, A.Y.7
-
122
-
-
34748891739
-
Recent advances in flavivirus antiviral drug discovery and vaccine development
-
Ray D., and Shi P.Y. Recent advances in flavivirus antiviral drug discovery and vaccine development. Recent Patents Anti-Infect. Drug Disc. 1 (2006) 45-55
-
(2006)
Recent Patents Anti-Infect. Drug Disc.
, vol.1
, pp. 45-55
-
-
Ray, D.1
Shi, P.Y.2
-
123
-
-
33748669852
-
West Nile virus 5′-cap structure is formed by sequential guanine N-7 and ribose 2′-O methylations by nonstructural protein 5
-
Ray D., Shah A., Tilgner M., Guo Y., Zhao Y.W., Dong H.P., Deas T.S., Zhou Y.S., Li H.M., and Shi P.Y. West Nile virus 5′-cap structure is formed by sequential guanine N-7 and ribose 2′-O methylations by nonstructural protein 5. J. Virol. 80 (2006) 8362-8370
-
(2006)
J. Virol.
, vol.80
, pp. 8362-8370
-
-
Ray, D.1
Shah, A.2
Tilgner, M.3
Guo, Y.4
Zhao, Y.W.5
Dong, H.P.6
Deas, T.S.7
Zhou, Y.S.8
Li, H.M.9
Shi, P.Y.10
-
124
-
-
0021863828
-
Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution
-
Rice C.M., Lenches E.M., Eddy S.R., Shin S.J., Sheets R.L., and Strauss J.H. Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution. Science 229 (1985) 726-733
-
(1985)
Science
, vol.229
, pp. 726-733
-
-
Rice, C.M.1
Lenches, E.M.2
Eddy, S.R.3
Shin, S.J.4
Sheets, R.L.5
Strauss, J.H.6
-
125
-
-
33646167045
-
Regulated cleavages at the West Nile virus NS4A-2K-NS4B junctions play a major role in rearranging cytoplasmic membranes and Golgi trafficking of the NS4A protein
-
Roosendaal J., Westaway E.G., Khromykh A., and Mackenzie J.M. Regulated cleavages at the West Nile virus NS4A-2K-NS4B junctions play a major role in rearranging cytoplasmic membranes and Golgi trafficking of the NS4A protein. J. Virol. 80 (2006) 4623-4632
-
(2006)
J. Virol.
, vol.80
, pp. 4623-4632
-
-
Roosendaal, J.1
Westaway, E.G.2
Khromykh, A.3
Mackenzie, J.M.4
-
127
-
-
33745273034
-
Structure-based mutational analysis of the NS3 helicase from dengue virus
-
Sampath A., Xu T., Chao A., Luo D.H., Lescar J., and Vasudevan S.G. Structure-based mutational analysis of the NS3 helicase from dengue virus. J. Virol. 80 (2006) 6686-6690
-
(2006)
J. Virol.
, vol.80
, pp. 6686-6690
-
-
Sampath, A.1
Xu, T.2
Chao, A.3
Luo, D.H.4
Lescar, J.5
Vasudevan, S.G.6
-
128
-
-
33745962422
-
Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerases
-
Selisko B., Dutartre H., Guillemot J.C., Debarnot C., Benarroch D., Khromykh A., Despres P., Egloff M.P., and Canard B. Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerases. Virology 351 (2006) 145-158
-
(2006)
Virology
, vol.351
, pp. 145-158
-
-
Selisko, B.1
Dutartre, H.2
Guillemot, J.C.3
Debarnot, C.4
Benarroch, D.5
Khromykh, A.6
Despres, P.7
Egloff, M.P.8
Canard, B.9
-
129
-
-
30744452734
-
Cleavage targets and the d-arginine-based inhibitors of the West Nile virus NS3 processing proteinase
-
Shiryaev S.A., Ratnikov B.I., Chekanov A.V., Sikora S., Rozanov D.V., Godzik A., Wang J., Smith J.W., Huang Z., Lindberg I., Samuel M.A., Diamond M.S., and Strongin A.Y. Cleavage targets and the d-arginine-based inhibitors of the West Nile virus NS3 processing proteinase. Biochem. J. 393 (2006) 503-511
-
(2006)
Biochem. J.
, vol.393
, pp. 503-511
-
-
Shiryaev, S.A.1
Ratnikov, B.I.2
Chekanov, A.V.3
Sikora, S.4
Rozanov, D.V.5
Godzik, A.6
Wang, J.7
Smith, J.W.8
Huang, Z.9
Lindberg, I.10
Samuel, M.A.11
Diamond, M.S.12
Strongin, A.Y.13
-
130
-
-
33846411423
-
Expression and purification of a two-component flaviviral proteinase resistant to autocleavage at the NS2B-NS3 junction region
-
Shiryaev S.A., Aleshin A.E., Ratnikov B.I., Smith J.W., Liddington R.C., and Strongin A.Y. Expression and purification of a two-component flaviviral proteinase resistant to autocleavage at the NS2B-NS3 junction region. Protein Exp. Purif. 52 (2007) 334-339
-
(2007)
Protein Exp. Purif.
, vol.52
, pp. 334-339
-
-
Shiryaev, S.A.1
Aleshin, A.E.2
Ratnikov, B.I.3
Smith, J.W.4
Liddington, R.C.5
Strongin, A.Y.6
-
131
-
-
33846883704
-
Cleavage preference distinguishes the two-component NS2B-NS3 serine proteinases of Dengue and West Nile viruses
-
Shiryaev S.A., Kozlov I.A., Ratnikov B.I., Smith J.W., Lebl M., and Strongin A.Y. Cleavage preference distinguishes the two-component NS2B-NS3 serine proteinases of Dengue and West Nile viruses. Biochem. J. 401 (2007) 743-752
-
(2007)
Biochem. J.
, vol.401
, pp. 743-752
-
-
Shiryaev, S.A.1
Kozlov, I.A.2
Ratnikov, B.I.3
Smith, J.W.4
Lebl, M.5
Strongin, A.Y.6
-
132
-
-
34247607600
-
Switching the substrate specificity of the two-component NS2B-NS3 flavivirus proteinase by structure-based mutagenesis
-
Shiryaev S.A., Ratnikov B.I., Aleshin A.E., Kozlov I.A., Nelson N.A., Lebl M., Smith J.W., Liddington R.C., and Strongin A.Y. Switching the substrate specificity of the two-component NS2B-NS3 flavivirus proteinase by structure-based mutagenesis. J. Virol. 81 (2007) 4501-4509
-
(2007)
J. Virol.
, vol.81
, pp. 4501-4509
-
-
Shiryaev, S.A.1
Ratnikov, B.I.2
Aleshin, A.E.3
Kozlov, I.A.4
Nelson, N.A.5
Lebl, M.6
Smith, J.W.7
Liddington, R.C.8
Strongin, A.Y.9
-
133
-
-
33847688459
-
Efficacy of orally administered T-705 on lethal avian influenza A (H5N1) virus infections in mice
-
Sidwell R.W., Barnard D.L., Day C.W., Smee D.F., Bailey K.W., Wong M.H., Morrey J.D., and Furuta Y. Efficacy of orally administered T-705 on lethal avian influenza A (H5N1) virus infections in mice. Antimicrob. Agents Chemother. 51 (2007) 845-851
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, pp. 845-851
-
-
Sidwell, R.W.1
Barnard, D.L.2
Day, C.W.3
Smee, D.F.4
Bailey, K.W.5
Wong, M.H.6
Morrey, J.D.7
Furuta, Y.8
-
134
-
-
33749042583
-
Flavivirus membrane fusion
-
Stiasny K., and Heinz F.X. Flavivirus membrane fusion. J. Gen. Virol. 87 (2006) 2755-2766
-
(2006)
J. Gen. Virol.
, vol.87
, pp. 2755-2766
-
-
Stiasny, K.1
Heinz, F.X.2
-
135
-
-
1542347705
-
Characterization of a membrane-associated trimeric low-pH-induced form of the class II viral fusion protein E from tick-borne encephalitis virus and its crystallization
-
Stiasny K., Bressanelli S., Lepault J., Rey F.A., and Heinz F.X. Characterization of a membrane-associated trimeric low-pH-induced form of the class II viral fusion protein E from tick-borne encephalitis virus and its crystallization. J. Virol. 78 (2004) 3178-3183
-
(2004)
J. Virol.
, vol.78
, pp. 3178-3183
-
-
Stiasny, K.1
Bressanelli, S.2
Lepault, J.3
Rey, F.A.4
Heinz, F.X.5
-
136
-
-
0027199917
-
Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes
-
Suzich J.A., Tamura J.K., Palmer Hill F., Warrener P., Grakoui A., Rice C.M., Feinstone S.M., and Collett M.S. Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes. J. Virol. 67 (1993) 6152-6158
-
(1993)
J. Virol.
, vol.67
, pp. 6152-6158
-
-
Suzich, J.A.1
Tamura, J.K.2
Palmer Hill, F.3
Warrener, P.4
Grakoui, A.5
Rice, C.M.6
Feinstone, S.M.7
Collett, M.S.8
-
137
-
-
33745596104
-
Inhibition of dengue virus replication by mycophenolic acid and ribavirin
-
Takhampunya R., Ubol S., Houng H.S., Cameron C.E., and Padmanabhan R. Inhibition of dengue virus replication by mycophenolic acid and ribavirin. J. Gen. Virol. 87 (2006) 1947-1952
-
(2006)
J. Gen. Virol.
, vol.87
, pp. 1947-1952
-
-
Takhampunya, R.1
Ubol, S.2
Houng, H.S.3
Cameron, C.E.4
Padmanabhan, R.5
-
138
-
-
0027254336
-
RNA-stimulated NTPase activity associated with the p80 protein of the pestivirus bovine viral diarrhea virus
-
Tamura J.K., Warrener P., and Collett M.S. RNA-stimulated NTPase activity associated with the p80 protein of the pestivirus bovine viral diarrhea virus. Virology 193 (1993) 1-10
-
(1993)
Virology
, vol.193
, pp. 1-10
-
-
Tamura, J.K.1
Warrener, P.2
Collett, M.S.3
-
139
-
-
0029863798
-
Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity
-
Tan B.H., Fu J.L., Sugrue R.J., Yap E.H., Chan Y.C., and Tan Y.H. Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity. Virology 216 (1996) 317-325
-
(1996)
Virology
, vol.216
, pp. 317-325
-
-
Tan, B.H.1
Fu, J.L.2
Sugrue, R.J.3
Yap, E.H.4
Chan, Y.C.5
Tan, Y.H.6
-
140
-
-
0344642934
-
DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells
-
Tassaneetrithep B., Burgess T.H., Granelli-Piperno A., Trumpfherer C., Finke J., Sun W., Eller M.A., Pattanapanyasat K., Sarasombath S., Birx D.L., Steinman R.M., Schlesinger S., and Marovich M.A. DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells. J. Exp. Med. 197 (2003) 823-829
-
(2003)
J. Exp. Med.
, vol.197
, pp. 823-829
-
-
Tassaneetrithep, B.1
Burgess, T.H.2
Granelli-Piperno, A.3
Trumpfherer, C.4
Finke, J.5
Sun, W.6
Eller, M.A.7
Pattanapanyasat, K.8
Sarasombath, S.9
Birx, D.L.10
Steinman, R.M.11
Schlesinger, S.12
Marovich, M.A.13
-
141
-
-
0042591335
-
Architecture of the flaviviral replication complex-protease, nuclease, and detergents reveal encasement within double-layered membrane compartments
-
Uchil P.D., and Satchidanandam V. Architecture of the flaviviral replication complex-protease, nuclease, and detergents reveal encasement within double-layered membrane compartments. J. Biol. Chem. 278 (2003) 24388-24398
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 24388-24398
-
-
Uchil, P.D.1
Satchidanandam, V.2
-
142
-
-
33747338217
-
Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA
-
Umareddy I., Chao A., Sampath A., Gu F., and Vasudevan S.G. Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA. J. Gen. Virol. 87 (2006) 2605-2614
-
(2006)
J. Gen. Virol.
, vol.87
, pp. 2605-2614
-
-
Umareddy, I.1
Chao, A.2
Sampath, A.3
Gu, F.4
Vasudevan, S.G.5
-
143
-
-
0036932907
-
Intracellular localization and determination of a nuclear localization signal of the core protein of dengue virus
-
Wang S.H., Syu W.J., Huang K.J., Lei H.Y., Yao C.W., King C.C., and Hu S.T. Intracellular localization and determination of a nuclear localization signal of the core protein of dengue virus. J. Gen. Virol. 83 (2002) 3093-3102
-
(2002)
J. Gen. Virol.
, vol.83
, pp. 3093-3102
-
-
Wang, S.H.1
Syu, W.J.2
Huang, K.J.3
Lei, H.Y.4
Yao, C.W.5
King, C.C.6
Hu, S.T.7
-
144
-
-
0027446550
-
RNA-stimulated NTPase activity associated with yellow fever virus NS3 protein expressed in bacteria
-
Warrener P., Tamura J.K., and Collett M.S. RNA-stimulated NTPase activity associated with yellow fever virus NS3 protein expressed in bacteria. J. Virol. 67 (1993) 989-996
-
(1993)
J. Virol.
, vol.67
, pp. 989-996
-
-
Warrener, P.1
Tamura, J.K.2
Collett, M.S.3
-
145
-
-
0025865788
-
In vitro synthesis of West Nile virus proteins indicates that the amino-terminal segment of the NS3 protein contains the active centre of the protease which cleaves the viral polyprotein after multiple basic amino acids
-
Wengler G., Czaya G., Farber P.M., and Hegemann J.H. In vitro synthesis of West Nile virus proteins indicates that the amino-terminal segment of the NS3 protein contains the active centre of the protease which cleaves the viral polyprotein after multiple basic amino acids. J. Gen. Virol. 72 (1991) 851-858
-
(1991)
J. Gen. Virol.
, vol.72
, pp. 851-858
-
-
Wengler, G.1
Czaya, G.2
Farber, P.M.3
Hegemann, J.H.4
-
146
-
-
0030846512
-
Ultrastructure of Kunjin virus-infected cells: colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structures
-
Westaway E.G., MacKenzie J.M., Kenney M.T., Jones M.K., and Khromykh A.A. Ultrastructure of Kunjin virus-infected cells: colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structures. J. Virol. 71 (1997) 6650-6661
-
(1997)
J. Virol.
, vol.71
, pp. 6650-6661
-
-
Westaway, E.G.1
MacKenzie, J.M.2
Kenney, M.T.3
Jones, M.K.4
Khromykh, A.A.5
-
147
-
-
0033602697
-
Nascent flavivirus RNA colocalized in situ with double-stranded RNA in stable replication complexes
-
Westaway E.G., Khromykh A.A., and Mackenzie J.M. Nascent flavivirus RNA colocalized in situ with double-stranded RNA in stable replication complexes. Virology 258 (1999) 108-117
-
(1999)
Virology
, vol.258
, pp. 108-117
-
-
Westaway, E.G.1
Khromykh, A.A.2
Mackenzie, J.M.3
-
148
-
-
23244450531
-
Structure of the flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing
-
Wu J.H., Bera A.K., Kuhn R.J., and Smith J.L. Structure of the flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing. J. Virol. 79 (2005) 10268-10277
-
(2005)
J. Virol.
, vol.79
, pp. 10268-10277
-
-
Wu, J.H.1
Bera, A.K.2
Kuhn, R.J.3
Smith, J.L.4
-
150
-
-
34247873039
-
Helicases as antiviral and anticancer drug targets
-
Xi X.G. Helicases as antiviral and anticancer drug targets. Curr. Med. Chem. 14 (2007) 883-915
-
(2007)
Curr. Med. Chem.
, vol.14
, pp. 883-915
-
-
Xi, X.G.1
-
151
-
-
23244464646
-
Structure of the Dengue virus helicase/nucleoside triphosphatase catalytic domain at a resolution of 2.4 angstrom
-
Xu T., Sampath A., Chao A., Wen D.Y., Nanao M., Chene P., Vasudevan S.G., and Lescar J. Structure of the Dengue virus helicase/nucleoside triphosphatase catalytic domain at a resolution of 2.4 angstrom. J. Virol. 79 (2005) 10278-10288
-
(2005)
J. Virol.
, vol.79
, pp. 10278-10288
-
-
Xu, T.1
Sampath, A.2
Chao, A.3
Wen, D.Y.4
Nanao, M.5
Chene, P.6
Vasudevan, S.G.7
Lescar, J.8
-
152
-
-
40849130890
-
Crystal structure of the catalytic domain of Japanese encephalitis virus NS3 helicase/nucleoside triphosphatase at a resolution of 1.8 angstrom
-
Yamashita T., Unno H., Mori Y., Tani H., Moriishi K., Takamizawa A., Agoh M., Tsukihara T., and Matsuura Y. Crystal structure of the catalytic domain of Japanese encephalitis virus NS3 helicase/nucleoside triphosphatase at a resolution of 1.8 angstrom. Virology 373 (2008) 426-436
-
(2008)
Virology
, vol.373
, pp. 426-436
-
-
Yamashita, T.1
Unno, H.2
Mori, Y.3
Tani, H.4
Moriishi, K.5
Takamizawa, A.6
Agoh, M.7
Tsukihara, T.8
Matsuura, Y.9
-
153
-
-
34247610261
-
Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-Angstrom resolution
-
Yap T.L., Xu T., Chen Y.L., Malet H., Egloff M.P., Canard B., Vasudevan S.G., and Lescar J. Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-Angstrom resolution. J. Virol. 81 (2007) 4753-4765
-
(2007)
J. Virol.
, vol.81
, pp. 4753-4765
-
-
Yap, T.L.1
Xu, T.2
Chen, Y.L.3
Malet, H.4
Egloff, M.P.5
Canard, B.6
Vasudevan, S.G.7
Lescar, J.8
-
154
-
-
53249130750
-
Mouse models of dengue virus infection and disease
-
Yauch L.E., and Shresta S. Mouse models of dengue virus infection and disease. Antiviral Res. 80 (2008) 87-93
-
(2008)
Antiviral Res.
, vol.80
, pp. 87-93
-
-
Yauch, L.E.1
Shresta, S.2
-
155
-
-
27744520272
-
Peptide inhibitors of dengue virus NS3 protease. Part 2. SAR study of tetrapeptide aldehyde inhibitors
-
Yin Z., Patel S.J., Wang W.L., Chan W.L., Ranga Rao K.R., Wang G., Ngew X., Patel V., Beer D., Knox J.E., Ma N.L., Ehrhardt C., Lim S.P., Vasudevan S.G., and Keller T.H. Peptide inhibitors of dengue virus NS3 protease. Part 2. SAR study of tetrapeptide aldehyde inhibitors. Bioorg. Med. Chem. Lett. 16 (2006) 40-43
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 40-43
-
-
Yin, Z.1
Patel, S.J.2
Wang, W.L.3
Chan, W.L.4
Ranga Rao, K.R.5
Wang, G.6
Ngew, X.7
Patel, V.8
Beer, D.9
Knox, J.E.10
Ma, N.L.11
Ehrhardt, C.12
Lim, S.P.13
Vasudevan, S.G.14
Keller, T.H.15
-
156
-
-
27744581672
-
Peptide inhibitors of Dengue virus NS3 protease. Part 1. Warhead
-
Yin Z., Patel S.J., Wang W.L., Wang G., Chan W.L., Rao K.R., Alam J., Jeyaraj D.A., Ngew X., Patel V., Beer D., Lim S.P., Vasudevan S.G., and Keller T.H. Peptide inhibitors of Dengue virus NS3 protease. Part 1. Warhead. Bioorg. Med. Chem. Lett. 16 (2006) 36-39
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 36-39
-
-
Yin, Z.1
Patel, S.J.2
Wang, W.L.3
Wang, G.4
Chan, W.L.5
Rao, K.R.6
Alam, J.7
Jeyaraj, D.A.8
Ngew, X.9
Patel, V.10
Beer, D.11
Lim, S.P.12
Vasudevan, S.G.13
Keller, T.H.14
-
157
-
-
35548989664
-
Mosquito La protein binds to the 3' untranslated region of the positive and negative polarity dengue virus RNAs and relocates to the cytoplasm of infected cells
-
Yocupicio-Monroy M., Padmanabhan R., Medina F., and del Angel R.M. Mosquito La protein binds to the 3' untranslated region of the positive and negative polarity dengue virus RNAs and relocates to the cytoplasm of infected cells. Virology 357 (2007) 29-40
-
(2007)
Virology
, vol.357
, pp. 29-40
-
-
Yocupicio-Monroy, M.1
Padmanabhan, R.2
Medina, F.3
del Angel, R.M.4
-
158
-
-
22844443626
-
Modulation of the nucleoside triphosphatase/RNA helicase and 5′-RNA triphosphatase activities of dengue virus type 2 nonstructural protein 3 (NS3) by interaction with NS5, the RNA-dependent RNA polymerase
-
Yon C., Teramoto T., Mueller N., Phelan J., Ganesh V.K., Murthy K.H., and Padmanabhan R. Modulation of the nucleoside triphosphatase/RNA helicase and 5′-RNA triphosphatase activities of dengue virus type 2 nonstructural protein 3 (NS3) by interaction with NS5, the RNA-dependent RNA polymerase. J. Biol. Chem. 280 (2005) 27412-27419
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 27412-27419
-
-
Yon, C.1
Teramoto, T.2
Mueller, N.3
Phelan, J.4
Ganesh, V.K.5
Murthy, K.H.6
Padmanabhan, R.7
-
159
-
-
0033585015
-
A novel in vitro replication system for Dengue virus. Initiation of RNA synthesis at the 3′-end of exogenous viral RNA templates requires 5′- and 3′-terminal complementary sequence motifs of the viral RNA
-
You S., and Padmanabhan R. A novel in vitro replication system for Dengue virus. Initiation of RNA synthesis at the 3′-end of exogenous viral RNA templates requires 5′- and 3′-terminal complementary sequence motifs of the viral RNA. J. Biol. Chem. 274 (1999) 33714-33722
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33714-33722
-
-
You, S.1
Padmanabhan, R.2
-
160
-
-
0035844132
-
In vitro RNA synthesis from exogenous dengue viral RNA templates requires long range interactions between 5′- and 3′-terminal regions that influence RNA structure
-
You S., Falgout B., Markoff L., and Padmanabhan R. In vitro RNA synthesis from exogenous dengue viral RNA templates requires long range interactions between 5′- and 3′-terminal regions that influence RNA structure. J. Biol. Chem. 276 (2001) 15581-15591
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 15581-15591
-
-
You, S.1
Falgout, B.2
Markoff, L.3
Padmanabhan, R.4
-
161
-
-
41349112304
-
Structure of the immature dengue virus at low pH primes proteolytic maturation
-
Yu I.M., Zhang W., Holdaway H.A., Li L., Kostyuchenko V.A., Chipman P.R., Kuhn R.J., Rossmann M.G., and Chen J. Structure of the immature dengue virus at low pH primes proteolytic maturation. Science 319 (2008) 1834-1837
-
(2008)
Science
, vol.319
, pp. 1834-1837
-
-
Yu, I.M.1
Zhang, W.2
Holdaway, H.A.3
Li, L.4
Kostyuchenko, V.A.5
Chipman, P.R.6
Kuhn, R.J.7
Rossmann, M.G.8
Chen, J.9
-
162
-
-
41849125306
-
Specific requirements for elements of the 5′ and 3′ terminal regions in flavivirus RNA synthesis and viral replication
-
Yu L., Nomaguchi M., Padmanabhan R., and Markoff L. Specific requirements for elements of the 5′ and 3′ terminal regions in flavivirus RNA synthesis and viral replication. Virology 374 (2008) 170-185
-
(2008)
Virology
, vol.374
, pp. 170-185
-
-
Yu, L.1
Nomaguchi, M.2
Padmanabhan, R.3
Markoff, L.4
-
163
-
-
0034616194
-
Purified NS2B/NS3 serine protease of dengue virus type 2 exhibits cofactor NS2B dependence for cleavage of substrates with dibasic amino acids in vitro
-
Yusof R., Clum S., Wetzel M., Murthy H.M., and Padmanabhan R. Purified NS2B/NS3 serine protease of dengue virus type 2 exhibits cofactor NS2B dependence for cleavage of substrates with dibasic amino acids in vitro. J. Biol. Chem. 275 (2000) 9963-9969
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9963-9969
-
-
Yusof, R.1
Clum, S.2
Wetzel, M.3
Murthy, H.M.4
Padmanabhan, R.5
-
164
-
-
0026471347
-
Processing and localization of dengue virus type-2 polyprotein precursor NS3-NS4a-NS4b-NS5
-
Zhang L.W., Mohan P.M., and Padmanabhan R. Processing and localization of dengue virus type-2 polyprotein precursor NS3-NS4a-NS4b-NS5. J. Virol. 66 (1992) 7549-7554
-
(1992)
J. Virol.
, vol.66
, pp. 7549-7554
-
-
Zhang, L.W.1
Mohan, P.M.2
Padmanabhan, R.3
-
165
-
-
0141567430
-
Ring-expanded ("fat") nucleoside and nucleotide analogues exhibit potent in vitro activity against Flaviviridae NTPases/helicases, including those of the West Nile virus, hepatitis C virus, and Japanese encephalitis virus
-
Zhang N., Chen H.M., Koch V., Schmitz H., Liao C.L., Bretner M., Bhadti V.S., Fattom A.I., Naso R.B., Hosmane R.S., and Borowski P. Ring-expanded ("fat") nucleoside and nucleotide analogues exhibit potent in vitro activity against Flaviviridae NTPases/helicases, including those of the West Nile virus, hepatitis C virus, and Japanese encephalitis virus. J. Med. Chem. 46 (2003) 4149-4164
-
(2003)
J. Med. Chem.
, vol.46
, pp. 4149-4164
-
-
Zhang, N.1
Chen, H.M.2
Koch, V.3
Schmitz, H.4
Liao, C.L.5
Bretner, M.6
Bhadti, V.S.7
Fattom, A.I.8
Naso, R.B.9
Hosmane, R.S.10
Borowski, P.11
-
166
-
-
0142124186
-
Potent inhibition of NTPase/helicase of the West Nile virus by ring-expanded ("Fat") nucleoside analogues
-
Zhang N., Chen H.M., Koch V., Schmitz H., Minczuk M., Stepien P., Fattom A.I., Naso R.B., Kalicharran K., Borowski P., and Hosmane R.S. Potent inhibition of NTPase/helicase of the West Nile virus by ring-expanded ("Fat") nucleoside analogues. J. Med. Chem. 46 (2003) 4776-4789
-
(2003)
J. Med. Chem.
, vol.46
, pp. 4776-4789
-
-
Zhang, N.1
Chen, H.M.2
Koch, V.3
Schmitz, H.4
Minczuk, M.5
Stepien, P.6
Fattom, A.I.7
Naso, R.B.8
Kalicharran, K.9
Borowski, P.10
Hosmane, R.S.11
-
167
-
-
47049089643
-
Genetic interactions among the West Nile virus methyltransferase, the RNA-dependent RNA polymerase, and the 5′ stem-loop of genomic RNA
-
Zhang B., Dong H., Zhou Y., and Shi P.Y. Genetic interactions among the West Nile virus methyltransferase, the RNA-dependent RNA polymerase, and the 5′ stem-loop of genomic RNA. J. Virol. 82 (2008) 7047-7058
-
(2008)
J. Virol.
, vol.82
, pp. 7047-7058
-
-
Zhang, B.1
Dong, H.2
Zhou, Y.3
Shi, P.Y.4
-
168
-
-
34247113349
-
Structure and function of flavivirus NS5 methyltransferase
-
Zhou Y.S., Ray D., Zhao Y.W., Dong H.P., Ren S.P., Li Z., Guo Y., Bernard K.A., Shi P.Y., and Li H.M. Structure and function of flavivirus NS5 methyltransferase. J. Virol. 81 (2007) 3891-3903
-
(2007)
J. Virol.
, vol.81
, pp. 3891-3903
-
-
Zhou, Y.S.1
Ray, D.2
Zhao, Y.W.3
Dong, H.P.4
Ren, S.P.5
Li, Z.6
Guo, Y.7
Bernard, K.A.8
Shi, P.Y.9
Li, H.M.10
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