Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses

European Journal of Biochemistry

Volumn 270, Issue 8, 2003, Pages 1645-1653

  Borowski, Peter ^a   Deinert, Johanna ^a   Schalinski, Sarah ^a   Bretner, Maria ^b   Ginalski, Krzysztof ^c,d   Kulikowski, Tadeusz ^b   Shugar, David ^b,d  

^a BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^b INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^c BIOINFOBANK INSTITUTE   (Poland)

^d UNIVERSITY OF WARSAW   (Poland)

Author keywords

Halogenated benzimidazoles benzotriazoles; Hepatitis C and related viruses; Inhibitors; NTPase helicases

Indexed keywords

4,5,6,7 TETRABROMOBENZOTRIAZOLE; 4,5,6,7 TETRACHLOROBENZOTRIAZOLE; 5,6 DIBROMO 1 (BETA RIBOFURANOSYL)BENZIMIDAZOLE; 5,6 DICHLORO 1 (BETA RIBOFURANOSYL)BENZIMIDAZOLE; 5,6 DICHLORO 1 (BETA RIBOFURANOSYL)BENZOTRIAZOLE; 5,6 DIMETHYL 1 (ALPHA RIBOFURANOSYL)BENZIMIDAZOLE; ADENOSINE TRIPHOSPHATE; BENZIMIDAZOLE DERIVATIVE; BENZOTRIAZOLE DERIVATIVE; CASEIN KINASE II; DNA; HELICASE; NONSTRUCTURAL PROTEIN 3; NUCLEOTIDE TRIPHOSPHATASE; PHOSPHATASE; PROTEIN; RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME SPECIFICITY; HEPATITIS C VIRUS; IC 50; INCUBATION TIME; JAPANESE ENCEPHALITIS VIRUS; NONHUMAN; PRIORITY JOURNAL; VERO CELL; WEST NILE FLAVIVIRUS;

ACID ANHYDRIDE HYDROLASES; ADENOSINE TRIPHOSPHATASES; ANTIVIRAL AGENTS; BENZIMIDAZOLES; BINDING SITES; DNA HELICASES; HEPACIVIRUS; KINETICS; MODELS, MOLECULAR; NUCLEOSIDE-TRIPHOSPHATASE; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY; TRIAZOLES; VIRAL NONSTRUCTURAL PROTEINS;

ANIMALIA; FLAVIVIRUS; HEPATITIS C VIRUS; JAPANESE ENCEPHALITIS VIRUS; RNA VIRUSES; WEST NILE VIRUS;

EID: 0038747996     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2003.03540.x     Document Type: Article

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