Highly pathogenic RNA viral infections: Challenges for antiviral research

Antiviral Research

Volumn 78, Issue 1, 2008, Pages 1-8

  Bray, Mike ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Alphavirus; Antiviral drug; Antiviral therapy; Arbovirus; Arenavirus; Argentine hemorrhagic fever; Biodefense; Bunyavirus; Crimean Congo hemorrhagic fever; Ebola hemorrhagic fever; Emerging infectious diseases; Filovirus; Flavivirus; Foot and mouth disease; H5N1 influenza; Hantavirus; Hantavirus pulmonary syndrome; Influenza; Japanese encephalitis; Junin virus; Lassa fever; Lassa virus; Livestock diseases; Marburg hemorrhagic fever; Viral encephalitis; Viral hemorrhagic fever; Yellow fever; Zoonosis

Indexed keywords

ALPHA2A INTERFERON; GUANOSINE DERIVATIVE; IMMUNOGLOBULIN; RIBAVIRIN; SIALIDASE INHIBITOR; VIRUS VACCINE;

DIAGNOSTIC PROCEDURE; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFICACY; EBOLA VIRUS; EPIDEMIC; EPIDEMIC ENCEPHALITIS; FILOVIRUS; FOOT AND MOUTH DISEASE; GEOGRAPHIC DISTRIBUTION; HANTAVIRUS PULMONARY SYNDROME; HEMORRHAGIC FEVER; HOST; HUMAN; INFLUENZA VIRUS A; INFLUENZA VIRUS A H5N1; JUNIN VIRUS; LASSA FEVER; MARBURG VIRUS; MEDICAL RESEARCH; NONHUMAN; NUTRITION; POULTRY; PRIORITY JOURNAL; REVIEW; RNA VIRUS; SWINE DISEASE; VIRUS ENCEPHALITIS; VIRUS INFECTION; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TRANSMISSION; VIRUS TYPING; WELLBEING; YELLOW FEVER; ZOONOSIS;

ANIMALS; ANIMALS, DOMESTIC; ANTIVIRAL AGENTS; DISEASE OUTBREAKS; HUMANS; PUBLIC HEALTH; RESEARCH; RNA VIRUS INFECTIONS; RNA VIRUSES; ZOONOSES;

ALPHAVIRUS; ANIMALIA; ARBOVIRUS; ARENAVIRUS; AVES; FLAVIVIRUS; HANTAVIRUS; INFLUENZA A VIRUS; JAPANESE ENCEPHALITIS VIRUS; JUNIN VIRUS; LASSA VIRUS; MARBURGVIRUS; ORTHOBUNYAVIRUS; ORTHOMYXOVIRIDAE; RNA VIRUSES; SUIDAE;

EID: 40849120543     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2007.12.007     Document Type: Review

References (35)

1. Akinfeeva L.A., Aksionova O.I., Vasilevich L.V., Gin'ko Z.L., Zar'kov K.A., Katkova L.R., Kuzovlev O.P., Kuzubov V.I., Lokteva L.I., and Ryabchikova E.I. A case of Ebola hemorrhagic fever. Infekt. Bolezn. 3 (2005) 85-88 [in Russian]
2. Bausch D., Sprecher A.G., Jeffs B., and Boumandouki P. Treatment of Marburg and Ebola hemorrhagic fevers: a strategy for testing new drugs and vaccines under outbreak conditions. Antiviral Res. 78 (2008) 150-161
3. Beigel J., and Bray M. Current and future antiviral therapy of severe influenza A virus infections. Antiviral Res. 78 (2008) 91-102
4. Bray M. Pathogenesis of viral hemorrhagic fever. Curr. Opin. Immunol. 17 (2005) 399-403
5. Bray M., and Geisbert T. Ebola virus: role of macrophages and dendritic cells in the pathogenesis of Ebola hemorrhagic fever. Int. J. Biochem. Cell Biol. 37 (2005) 1560-1566
6. Bray M., and Mahanty S. Ebola hemorrhagic fever and septic shock. J. Infect. Dis. 188 (2003) 1613-1617
7. Bray M., and Murphy F. Filovirus research: knowledge expands to meet a growing threat. J. Infect. Dis. 196 Suppl. 2 (2007) S438-S443
8. Coutard B., Gorbalenya A., Snijder E., Leontovitch A., Poupon A., De Lamballerie X., Charrel R., Gould E., Günther S., Norder H., Klempa B., Bourhy H., Rohayem J., L'Hermite E., Nordlund P., Stuart D., Owens R., Grimes J., Tucker P., Bolognesi M., Mattevi A., Coll M., Jones T.A., Aqvist J., Unge T., Hilgenfeld R., Bricogne G., Neyts J., La Colla P., Puerstinger G., Gonzalez J.P., Leroy E., Cambillau C., Romette J.L., and Canard B. The VIZIER project: preparedness against pathogenic RNA viruses. Antiviral Res. 78 (2008) 37-46
9. Daddario-DiCaprio K.M., Geisbert T.W., Stroher U., Geisbert J.B., Grolla A., Fritz E.A., Fernando L., Kagan E., Jahrling P.B., Hensley L.E., Jones S.M., and Feldmann H. Postexposure protection against Marburg haemorrhagic fever with recombinant vesicular stomatitis virus vectors in non-human primates: an efficacy assessment. Lancet 367 (2006) 1399-1404
10. Enria D., Briggiler A., and Sanchez Z. Treatment of Argentine hemorrhagic fever. Antiviral Res. 78 (2008) 132-139
11. Ergonul O. Treatment of Crimean-Congo hemorrhagic fever. Antiviral Res. 78 (2008) 125-131
12. Geisbert T.W., and Jahrling P.B. Exotic emerging viral diseases: progress and challenges. Nat. Med. 10 Suppl. 12 (2004) S110-S121
13. Goris N., Vandenbussche F., and De Clercq K. Potential of antiviral prophylaxis and therapy for controlling RNA viral infections of livestock. Antiviral Res. 78 (2008) 170-178
14. Gould E., Solomon T., and Mackenzie J. Does antiviral therapy have a role in the control of Japanese encephalitis?. Antiviral Res. 78 (2008) 140-149
15. Gowen B., and Holbrook M. Animal models of highly pathogenic RNA viral infections: hemorrhagic fever viruses. Antiviral Res. 78 (2008) 79-90
16. Greenstone H., Spinelli E., Tseng C., Taylor K., and Laughlin C. NIAID resources for developing new therapies for severe viral infections. Antiviral Res. 78 (2008) 51-59
17. Hensley L., Stevens E., Yan S., Geisbert J., Macias W., Larsen T., Daddario-DiCaprio K., Cassell G., Jahrling P., and Geisbert T. Recombinant human activated protein C for the postexposure treatment of Ebola hemorrhagic fever. J. Infect. Dis. 196 Suppl. 2 (2007) S390-S399
18. Higgs E., Hayden F., Chotpitayasunondh T., Whitworth J., and Farrar J. The Southeast Asian Influenza Clinical Research Network: development and challenges for a new multilateral research endeavor. Antiviral Res. 78 (2008) 64-68
19. Holbrook M., and Gowen B. Animal models of highly pathogenic RNA viral infections: encephalitis viruses. Antiviral Res. 78 (2008) 69-78
20. Jahrling P.B., Hesse R.A., Eddy G.A., Johnson K.M., Callis R.T., and Stephen E.L. Lassa virus infection of rhesus monkeys: pathogenesis and treatment with ribavirin. J. Infect. Dis. 141 (1980) 580-589
21. Jonsson C., Hooper J., and Mertz G. Treatment of hantavirus pulmonary syndrome. Antiviral Res. 78 (2008) 162-169
22. Khan S.K., Goba A., Chu M., Roth C., Healing T., and Bausch D. New opportunities for research in the pathogenesis and treatment of Lassa fever. Antiviral Res. 78 (2008) 103-115
23. Kuhn P., and Canard B. International research networks in viral structural proteonomics: again, lessons from SARS. Antiviral Res. 78 (2008) 47-50
24. Kumar P., Wu H., McBride J.L., Jung K.E., Kim M.H., Davidson B.L., Lee S.K., Shankar P., and Manjunath N. Transvascular delivery of small interfering RNA to the central nervous system. Nature 448 (2007) 39-43
25. Leyssen P., De Clercq E., and Neyts J. Molecular strategies to inhibit the replication of RNA viruses. Antiviral Res. 78 (2008) 9-25
26. Mackenzie J.S., Gubler D.J., and Petersen L.R. Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses. Nat. Med. 10 Suppl. 12 (2004) S98-S109
27. McCormick J.B., King I.J., Webb P.A., Scribner C.L., Craven R.B., Johnson K.M., Elliott L.H., and Belmont-Williams R. Lassa fever. Effective therapy with ribavirin. N. Engl. J. Med. 314 (1986) 20-26
28. Mertz G.J., Miedzinski L., Goade D., Pavia A.T., Hjelle B., Hansbarger C.O., Levy H., Koster F.T., Baum K., Lindemulder A., Wang W., Riser L., Fernandez H., Whitley R.J., and Collaborative Antiviral Study Group. Placebo-controlled, double-blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America. Clin. Infect. Dis. 39 (2004) 1307-1313
29. Monath T. Treatment of yellow fever. Antiviral Res. 78 (2008) 116-124
30. Nalca A., and Whitehouse C. Crimean-Congo hemorrhagic fever virus infection among animals. In: Ergonul O., and Whitehouse C.A. (Eds). Crimean Congo Hemorrhagic Fever: A Global Perspective (2007), Springer, Dordrecht, NL 155-165
31. Pardridge W.M. Drug targeting to the brain. Pharm. Res. 24 (2007) 1733-1744
32. Roberts R., Styrt B., and McCune S. FDA perspective on antivirals against biothreats: communicate early and often. Antiviral Res. 78 (2008) 60-63
33. Solomon T., Dung N.M., Wills B., Kneen R., Gainsborough M., Diet T.V., Thuy T.T., Loan H.T., Khanh V.C., Vaughn D.W., White N.J., and Farrar J.J. Interferon alfa-2a in Japanese encephalitis: a randomised double-blind placebo-controlled trial. Lancet 361 (2003) 821-826
34. Spurgers K., Sharkey C.M., Warfield K., and Bavari S. Oligonucleotide antiviral therapeutics: antisense and RNA interference for highly pathogenic RNA viral infections. Antiviral Res. 78 (2008) 26-36
35. Vatansever Z., Uzun R., Estrada-Pena A., and Ergonul O. Crimean-Congo hemorrhagic fever in Turkey. In: Ergonul O., and Whitehouse C.A. (Eds). Crimean Congo Hemorrhagic Fever: A Global Perspective (2007), Springer, Dordrecht, NL 59-74