La protein binds to NS5 and NS3 and to the 5′ and 3′ ends of Dengue 4 virus RNA

Virus Research

Volumn 102, Issue 2, 2004, Pages 141-150

  García Montalvo, Beatriz María ^a   Medina, Fernando ^a   Del Angel, Rosa M ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Dengue; La; NS3; NS5; Replication

Indexed keywords

BIOTIN; CELL PROTEIN; LA ANTIGEN; PHOSPHORUS 32; STRUCTURAL PROTEIN; VIRUS RNA;

ARTICLE; CELL LINE; CROSS LINKING; CYCLIZATION; DATA ANALYSIS; DENGUE VIRUS; EXTRACT; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; ULTRAVIOLET RADIATION; UNTRANSLATED REGION; VIRUS GENOME; VIRUS REPLICATION;

3' UNTRANSLATED REGIONS; 5' UNTRANSLATED REGIONS; AUTOANTIGENS; CELL LINE; DENGUE VIRUS; HUMANS; MONOCYTES; PROTEIN BINDING; RIBONUCLEOPROTEINS; RNA HELICASES; RNA, VIRAL; RNA-BINDING PROTEINS; SERINE ENDOPEPTIDASES; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

DENGUE VIRUS;

EID: 1842861928     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virusres.2004.01.024     Document Type: Article

References (44)

1. Ali N., Siddiqui A. Interaction of polypyrimidine tract-binding protein with the 5′ noncoding region of the hepatitis C virus RNA genome and its functional requirement in internal initiation of translation. J. Virol. 69:1995;6367-6375.
2. Bachmann M., Falke D., Schroder H.C., Muller W.E.G. Intracellular distribution of the La antigen in CV-1 cells after herpes simplex virus type 1 infection compared with the localization of U small nuclear ribonucleoprotein particles. J. Gen. Virol. 70:1989;881-891.
3. Blackwell J.L., Brinton M.A. Translation elongation factor-1 alpha interacts with the 3′ stem-loop region of West Nile virus genomic RNA. J. Virol. 71:1997;6433-6444.
4. Brinton M.A., Fernandez A.V., Dispoto J.H. The 3′-nucleotides of flavivirus genomic RNA form a conserved secondary structure. Virology. 153:1986;113-121.
5. Brinton M.A., Dispoto J.H. Sequence and secondary structure analysis of the 5′-terminal region of flavivirus genome RNA. Virology. 162:1988;290-299.
6. Cahour A., Pletnev A., Vazeille-Falcoz M., Rosen L., Lai C.-J. Growth-restricted dengue virus mutants containing deletions in the 5′ noncoding region of the RNA genome. Virology. 207:1995;68-76.
7. Chen C.J., Kuo M.D., Chien L.J., Hsu S.L., Wang Y.M., Lin J.H. RNA-protein interactions: involvement of NS3, NS5, and 3′ noncoding regions of Japanese encephalitis virus genomic RNA. J. Virol. 71:1997;3466-3473.
8. Chu P.W.G., Westaway E.G. Replication strategy of Kunjin virus: evidence for recycling role of replicative form RNA as a template in semiconservative and asymmetric replication. Virology. 140:1985;68-79.
9. Cui T., Sugrue R.J., Xu Q., Lee A.K.W., Chan Y.-C., Fu J. Recombinant dengue virus type 1 NS3 protein exhibits specific viral RNA binding and NTPase activity regulated by the NS5 protein. Virology. 246:1998;409-417.
10. De B.P., Gupta S., Zhao H., Drazba J.A., Banerjee A.K. Specific interaction in vitro and in vivo of glyceraldehyde-3-phosphate dehydrogenase and La protein with cis-acting RNAs of human parainfluenza virus type 3. J. Biol. Chem. 271:1996;24728-24735.
11. De Nova-Ocampo M., Villegas-Sepulveda N., del Angel R.M. Translation elongation-1α, La, and PTB interact with the 3′ untranslated region of dengue 4 virus RNA. Virology. 295:2002;337-347.
12. Fodor E., Pritlove D.C., Brownlee G.G. The influenza virus panhandle is involved in the initiation of transcription. J. Virol. 68:1994;4092-4096.
13. Gottlieb E., Stelitz J.A. Function of the mammalian La protein: evidence for its action in transcription termination by RNA polymerase III. EMBO J. 8:1989;851-861.
14. Gould, E.A., Clegg, J.C., 1991. Growth, titration and purification of alphaviruses and flaviviruses. In: Mahy, B.W.J. (Ed.), Virology: A Practical Approach. IRL Press, Oxford University, London, pp. 43-78.
15. Grange T., Bouloy M., Girard M. Stable secondary structure at the 3′ end of the genome of yellow fever virus (17D vaccine strain). FEBS Lett. 188:1985;159-163.
16. Hahm B., Kim Y.K., Kim J.H., Kim T.Y., Jang S.K. Heterogeneous nuclear ribonucleoprotein L interacts with the 3′ border of the internal ribosomal entry site of hepatitis C virus. J. Virol. 72:1998;8782-8788.
17. Hahn C.S., Hahn Y.S., Rice C.M., Lee E., Dalgarno L., Strauss E.G., Strauss J.H. Conserved elements in the 3′ untranslated region of flavivirus RNAs and potential cyclization sequences. J. Mol. Biol. 198:1987;33-41.
18. Halstead S.B. Pathogenesis of dengue: challenges to molecular biology. Science. 239:1988;476-481.
19. Herold J., Andino R. Poliovirus RNA replication requires genome circularization through a protein-protein bridge. Mol. Cell. 7:2001;581-591.
20. Houshmand H., Bergqvist A. Interaction of hepatitis C virus NS5A with La protein revealed by T7 phage display. Biochem. Biophys. Res. Commun. 309:2003;695-701.
21. Huang P., Lai M.M.C. Heterogeneous nuclear ribonucleoprotein A1 binds to the 3′-untranslated region and mediates potential 5′-3′-end cross talks of mouse hepatitis virus RNA. J. Virol. 75:2001;5009-5017.
22. Hühn P., Prujin G.J., van Venrooij W.J., Bachmann M. Characterization of the autoantigen La (SS-B) as a dsRNA unwinding enzyme. Nucleic Acids Res. 25:1997;410-416.
23. Intine R.V., Tenenbaum S.A., Sakulich A.L., Keene J.D., Maraia R.J. Differential phosphorylation and subcellular localization of La RNPs associated with precursor tRNAs and translation-related mRNAs. Mol. Cell. 12:2003;1301-1307.
24. Keene J.D., Schubert M., Lazzarini R.A. Terminal sequences of vesicular stomatitis virus RNA are both complementary and conserved. J. Virol. 32:1979;167-174.
25. Kurilla M.G., Keene J.D. The leader RNA of vesicular stomatitis virus is bound by a cellular protein reactive with anti-La lupus antibodies. Cell. 34:1983;837-845.
26. Lin C., Wu J.W., Hsiao K., Su M.S. The hepatitis C virus NS4A protein: interactions with the NS4B and NS5A proteins. J. Virol. 71:1997;6465-6471.
27. Meerovitch K., Svitkin Y.V., Lee H.S., Lejbkowicz F., Kenan D.J., Chan E.K.L., Agol V.I., Keene J.D., Sonenberg N. La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. J. Virol. 67:1993;3798-3807.
28. Men R., Bray M., Clark D., Chanock R.M., Lai C.-J. Dengue type 4 virus mutants containing deletions in the 3′ noncoding region of the RNA genome: analysis of growth restriction in cell culture and altered viremia pattern and immunogenicity in rhesus monkeys. J. Virol. 70:1996;3930-3937.
29. Minta J.O., Pambrum L. In vitro induction of cytologic and functional differentiation of the immature human monocyte-like cell line U-937 with phorbol myristate acetate. Am. J. Pathol. 119:1985;111-126.
30. Mohan P.M., Padmanabhan R. Detection of stable secondary structure at the 3′ terminus of dengue virus type 2 RNA. Gene. 108:1991;185-191.
31. Olsthoorn R.C.L., Bol J.F. Sequence comparison and secondary structure analysis of the 3′ noncoding region of flavivirus genomes reveals multiple pseudoknots. RNA. 7:2001;1370-1377.
32. Pardigon N., Strauss N.H. Mosquito homolog of the La autoantigen binds to sindbis virus RNA. J. Virol. 70:1996;6075-6082.
33. Pogue G.P., Hofmann J., Duncan R., Best J.M., Etherington J., Sontheimer R.D., Nakhasi H.L. Autoantigens interacts with cis-acting elements of rubella virus RNA. J. Virol. 70:1996;6269-6277.
34. Singh N.K., Atreya Ch.D., Nakhasi H.L. Identification of calreticulin as a rubella virus RNA binding protein. Proc. Natl. Acad. Sci. U.S.A. 91:1994;12770-12774.
35. Spångberg K., Wiklund L., Schwartz S. Binding of the La autoantigen to the hepatitis C virus 3′ untranslated region protects the RNA from rapid degradation in vitro. J. Gen. Virol. 82:2001;113-120.
36. Takemagi T., Washizu M., Yasui K. Nucleotide sequence at the 3′ end of Japanese encephalitis virus genome RNA. Virology. 152:1986;483-486.
37. Tan B.-H., Fu J., Sugrue R.J., Yap E.-H., Chan Y.C., Tan Y.-H. Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity. Virology. 216:1996;317-325.
38. Uchil P.D., Satchidanandam V. Architecture of the flaviviral replication complex. J. Biol. Chem. 278:2003;24388-24398.
39. Wertz G.W., Whelan S., LeGrone A., Ball L.A. Extent of terminal complementary modulates the balance between transcription and replication of vesicular stomatitis virus RNA. Proc. Natl. Acad. Sci. U.S.A. 91:1994;8587-8591.
40. Wilusz J., Kurilla M.G., Keene J.D. A host protein (La) binds to a unique species of minus-sense leader RNA during replication of vesicular stomatitis virus. Proc. Natl. Acad. Sci. U.S.A. 80:1983;5827-5831.
41. Yocupicio-Monroy R.M.E., Medina F., Reyes-del Valle J., del Angel R.M. Cellular proteins from human monocytes bind to dengue 4 virus minus-strand 3′ untranslated region RNA. J. Virol. 77:2003;3067-3076.
42. You S., Falgout B., Markoff L., Padmanabhan R. In vitro RNA synthesis from exogenous dengue viral RNA templates requires long range interactions between 5′- and 3′-terminal regions that influence RNA structure. J. Biol. Chem. 276:2001;15581-15591.
43. You S., Padmanabhan R. A novel in vitro replication system for dengue virus. J. Biol. Chem. 274:1999;33714-33722.
44. Zheng H., Palese P., Garcia-Sastre A. Nonconserved nucleotides at the 3′ and 5′ ends of an influenza A virus RNA play an important role in viral RNA replication. Virology. 217:1996;242-251.