A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase

Journal of Virology

Volumn 80, Issue 1, 2006, Pages 149-160

  Paeshuyse, Jan ^a   Leyssen, Pieter ^a   Mabery, Eric ^b   Boddeker, Nina ^b   Vrancken, Robert ^c   Froeyen, Matheus ^a   Ansari, Israrul H ^d   Dutartre, Hélène ^e   Rozenski, Jef ^a   Gil, Laura H V G ^d   Letellier, Carine ^c   Lanford, Robert ^f   Canard, Bruno ^e   Koenen, Frank ^c   Kerkhofs, Pierre ^c   Donis, Ruben O ^d   Herdewijn, Piet ^a   Watson, Julia ^b   De Clercq, Erik ^a   Puerstinger, Gerhard ^g   Neyts, Johan ^a   more..

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b GILEAD SCIENCES   (United States)

^c VETERINARY AND AGROCHEMICAL RESEARCH CENTRE   (Belgium)

^d UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^e Centre National de la Recherche Scientifique   (France)

^f SOUTHWEST NATIONAL PRIMATE RESEARCH CENTER   (United States)

^g UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

5 [(4 BROMOPHENYL)METHYL] 2 PHENYL 5H IMIDAZO[4,5 C]PYRIDINE; ANTIVIRUS AGENT; N PROPYL N [2 (2H 1,2,4 TRIAZINO[5,6 B]INDOL 3 YLTHIO)ETHYL] 1 PROPANAMINE; PROPIONAMIDE DERIVATIVE; PYRIDINE DERIVATIVE; RNA DIRECTED RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VP 32947;

ANIMAL CELL; ARTICLE; CATTLE DISEASE; CELL STRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOPATHOGENIC EFFECT; ENZYME BINDING; ENZYME SPECIFICITY; HEPATITIS C VIRUS; IC 50; MOLECULAR CLONING; MOLECULAR STABILITY; NONHUMAN; PESTIVIRUS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; RNA SYNTHESIS; VIRUS INHIBITION; VIRUS MUTANT; VIRUS REPLICATION;

ANTIVIRAL AGENTS; DIARRHEA VIRUS 1, BOVINE VIRAL; DRUG RESISTANCE, VIRAL; IMIDAZOLES; LETHAL DOSE 50; MUTATION; PESTIVIRUS; PYRIDINES; RNA REPLICASE; RNA, VIRAL; TRIAZINES; TUMOR CELLS, CULTURED; VIRUS REPLICATION;

ANIMALIA; BOS TAURUS; BOVINE VIRAL DIARRHEA VIRUS 1; HEPACIVIRUS; HEPATITIS C VIRUS; PESTIVIRUS; YELLOW FEVER VIRUS;

EID: 33645966527     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.80.1.149-160.2006     Document Type: Article

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