The importance of permeability screening in drug discovery process: PAMPA, Caco-2 and rat everted gut assays

Current Topics in Pharmacology

Volumn 11, Issue 2, 2007, Pages 63-86

  Fortuna, Ana ^a   Alves, Gilberto ^a   Falcão, Amílcar ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Caco 2 cells assay; Drug discovery; PAMPA; Permeability screening; Rat everted gut assay

Indexed keywords

DRUG;

CELL ASSAY; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CULTURE MEDIUM; DRUG ABSORPTION; DRUG METABOLISM; DRUG PENETRATION; DRUG RESEARCH; DRUG SCREENING; DRUG SOLUBILITY; DRUG TRANSPORT; DRUG UPTAKE; HIGH THROUGHPUT SCREENING; INCUBATION TIME; LIPID COMPOSITION; NONHUMAN; PARALLEL ARTIFICIAL MEMBRANE PERMEABILITY ASSAY; PH; RAT EVERTED GUT ASSAY; REVIEW;

EID: 56749128029     PISSN: 09724559     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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