Physicochemical high throughput screening: Parallel artificial membrane permeation assay in the description of passive absorption processes

Journal of Medicinal Chemistry

Volumn 41, Issue 7, 1998, Pages 1007-1010

  Kansy, Manfred ^a   Senner, Frank ^a   Gubernator, Klaus ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALPRENOLOL; ATENOLOL; CEFALEXIN; CEFTRIAXONE; CHLORAMPHENICOL; CORTICOSTERONE; COUMARIN; DEXAMETHASONE; DILTIAZEM; GUANABENZ; HYDROCORTISONE; IMIPRAMINE; METOPROLOL; OLSALAZINE; PROPRANOLOL; SALAZOSULFAPYRIDINE; SALICYLIC ACID; SULPIRIDE; TERBUTALINE; TESTOSTERONE; THEOPHYLLINE; TIACRILAST; VERAPAMIL; WARFARIN;

ANALYTIC METHOD; ARTIFICIAL MEMBRANE; DRUG ABSORPTION; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG DETERMINATION; DRUG PENETRATION; LETTER; MEMBRANE PERMEABILITY; MOLECULAR WEIGHT; PH;

ABSORPTION; ADSORPTION; CACO-2 CELLS; DRUG EVALUATION, PRECLINICAL; HUMANS; HYDROGEN-ION CONCENTRATION; INTESTINAL ABSORPTION; MEMBRANES, ARTIFICIAL; PERMEABILITY; PHARMACOKINETICS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0032568397     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970530e     Document Type: Letter

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