The new pre-preclinical paradigm: compound optimization in early and late phase drug discovery.

Current topics in medicinal chemistry

Volumn 1, Issue 5, 2001, Pages 353-366

  Caldwell, G W ^a   Ritchie, D M ^a   Masucci, J A ^a   Hageman, W ^a   Yan, Z ^a  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG;

ANIMAL; BIOAVAILABILITY; CELL CULTURE; CHEMISTRY; DRUG SCREENING; GUINEA PIG; HUMAN; METABOLISM; METHODOLOGY; PHARMACOKINETICS; PHARMACOLOGY; RABBIT; RAT; REVIEW; STANDARD;

ANIMALS; BIOLOGICAL AVAILABILITY; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; GUINEA PIGS; HUMANS; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; PHARMACOLOGY; RABBITS; RATS;

MLCS; MLOWN;

EID: 0035523085     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568026013394949     Document Type: Review

References (103)