Determination of in vitro permeability of drug candidates through a Caco-2 cell monolayer by liquid chromatography/tandem mass spectrometry

Journal of Mass Spectrometry

Volumn 35, Issue 1, 2000, Pages 71-76

  Wang, Zhen ^a   Hop, Cornelis E C A ^a   Leung, Kwan H ^a   Pang, JianMei ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Caco 2 cells; In vitro absorption; Liquid chromatography tandem mass spectrometry; P glycoprotein

Indexed keywords

FINASTERIDE; GLYCOPROTEIN P; IBUTAMOREN; TESTOSTERONE;

ACCURACY; ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG ABSORPTION; DRUG PENETRATION; DRUG TRANSPORT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MONOLAYER CULTURE; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; CHROMATOGRAPHY, LIQUID; HUMANS; MASS SPECTROMETRY; P-GLYCOPROTEIN; PERMEABILITY; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS;

EID: 0033977587     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9888(200001)35:1<71::AID-JMS915>3.0.CO;2-5     Document Type: Article

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