Analysis of drug transport and metabolism in cell monolayer systems that have been modified by cytochrome P4503A4 cDNA-expression

European Journal of Pharmaceutical Sciences

Volumn 12, Issue 1, 2000, Pages 63-68

  Crespi, Charles L ^a   Fox, Lisa ^a   Stocker, Penny ^a   Hu, Ming ^b   Steimel, Dorothy T ^a  

^a Gentest Corporation   (United States)

^b WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Cytochrome P4503A4; Intestine; Nifedipine

Indexed keywords

CARBAMAZEPINE; CIMETIDINE; CYTOCHROME P450 3A4; GLYCOPROTEIN P; HYGROMYCIN B; ITRACONAZOLE; KETOCONAZOLE; MICONAZOLE; MIDAZOLAM; NIFEDIPINE; PROPRANOLOL; TESTOSTERONE; VERAPAMIL;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN; DRUG METABOLISM; DRUG TRANSPORT; HUMAN; HUMAN CELL; INTESTINE; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ATENOLOL; BIOLOGICAL TRANSPORT; CELL LINE; CELL MEMBRANE PERMEABILITY; CIMETIDINE; CYTOCHROME P-450 ENZYME SYSTEM; DNA, COMPLEMENTARY; ERYTHROMYCIN; GLUCOSE; HUMANS; MAMMALS; MANNITOL; MIXED FUNCTION OXYGENASES; PHARMACEUTICAL PREPARATIONS; PHENYLALANINE; PROPRANOLOL; RECOMBINANT PROTEINS; TESTOSTERONE; TUMOR CELLS, CULTURED; VERAPAMIL;

EID: 0033730856     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(00)00141-X     Document Type: Article

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