Greater than the sum of its parts: Combining models for useful ADMET prediction

Journal of Medicinal Chemistry

Volumn 48, Issue 4, 2005, Pages 1287-1291

  O'Brien, Sean E ^a   De Groot, Marcel J ^b  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^b ACCELRYS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2D6; DOFETILIDE; POTASSIUM CHANNEL HERG;

ARTICLE; ARTIFICIAL NEURAL NETWORK; BAYES THEOREM; CHEMICAL MODEL; DRUG ABSORPTION; DRUG DESIGN; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; DRUG TOXICITY;

BAYES THEOREM; CALCIUM CHANNEL BLOCKERS; CATION TRANSPORT PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG DESIGN; ENZYME INHIBITORS; ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; NEURAL NETWORKS (COMPUTER); PHENETHYLAMINES; POTASSIUM CHANNELS, VOLTAGE-GATED; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; STEROID 21-HYDROXYLASE; SULFONAMIDES;

EID: 13944268698     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049254b     Document Type: Article

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