Correlation between oral drug absorption in humans, and apparent drug permeability in TC-7 cells, A human epithelial intestinal cell line: Comparison with the parental Caco-2 cell line

Pharmaceutical Research

Volumn 15, Issue 5, 1998, Pages 726-733

  Grès, Marie Catherine ^a   Julian, Bernard ^a   Bourrié, Martine ^a   Meunier, Viviane ^a   Roques, Claude ^a   Berger, Marion ^a   Boulenc, Xavier ^a   Berger, Yves ^a   Fabre, Gérard ^a  

^a SANOFI   (France)

Author keywords

Caco 2 cells; In vitro absorption; In vitro in vivo relationship

Indexed keywords

AMOXICILLIN; ATENOLOL; CAFFEINE; CEFALEXIN; CYCLOSPORIN A; ENALAPRILAT; GLUTAMINE; HYDROCORTISONE; INULIN; MACROGOL 400; MACROGOL 4000; MANNITOL; METOPROLOL; PHENAZONE; PHENYLALANINE; PROPRANOLOL; SUCROSE; TAUROCHOLIC ACID; TERBUTALINE; TESTOSTERONE;

ACTIVE TRANSPORT; ARTICLE; CELL DENSITY; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CELL STRUCTURE; DRUG ABSORPTION; DRUG DIFFUSION; DRUG PENETRATION; ELECTRIC RESISTANCE; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; INTESTINE MUCOSA PERMEABILITY; MOLECULAR WEIGHT; MONOLAYER CULTURE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TIGHT JUNCTION;

ADMINISTRATION, ORAL; ANTI-BACTERIAL AGENTS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; EPITHELIAL CELLS; HUMANS; INTESTINAL ABSORPTION; MICROSCOPY, ELECTRON, SCANNING;

EID: 0031780682     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011919003030     Document Type: Article

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