The role of absorption, distribution, metabolism, excretion and toxicity in drug discovery.

Current topics in medicinal chemistry

Volumn 3, Issue 10, 2003, Pages 1125-1154

  Lin, Jing ^a   Sahakian, Diana C ^a   de Morais, Sonia M F ^a   Xu, Jinghai J ^a   Polzer, Robert J ^a   Winter, Steven M ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG;

ABSORPTION; ANIMAL; BIOAVAILABILITY; BIOLOGICAL MODEL; CLINICAL TRIAL; COMPUTER SIMULATION; DRUG DESIGN; DRUG INTERACTION; DRUG SCREENING; DRUG TOXICITY; HUMAN; PHARMACOKINETICS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; TISSUE DISTRIBUTION; TRANSPORT AT THE CELLULAR LEVEL;

ABSORPTION; ANIMALS; BIOLOGICAL AVAILABILITY; BIOLOGICAL TRANSPORT; CLINICAL TRIALS; COMPUTER SIMULATION; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; DRUG INTERACTIONS; DRUG TOXICITY; HUMANS; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION;

EID: 0038282311     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568026033452096     Document Type: Review

References (237)