-
1
-
-
0034611784
-
Medical strategies in the treatment of obesity
-
Bray GA, Tartaglia LA. Medical strategies in the treatment of obesity. Nature. 2000;404:672-7.
-
(2000)
Nature
, vol.404
, pp. 672-677
-
-
Bray, G.A.1
Tartaglia, L.A.2
-
2
-
-
0043169568
-
Leptin-induced adipose apoptosis. Implications for body weight regulation
-
Gullicksen PS, Della-Fera MA, Baile CA. Leptin-induced adipose apoptosis. Implications for body weight regulation. Apoptosis. 2003;8:327-35.
-
(2003)
Apoptosis
, vol.8
, pp. 327-335
-
-
Gullicksen, P.S.1
Della-Fera, M.A.2
Baile, C.A.3
-
3
-
-
0037330932
-
Inhibition of phosphatidylcholine synthesis induces expression of the endoplasmic reticulum stress and apoptosis-related protein CCAAT/enhancer- binding protein-homologous protein (CHOP/GADD153)
-
van der Sanden MHM, Houweling M, van Golde LM, Vaandrager AB. Inhibition of phosphatidylcholine synthesis induces expression of the endoplasmic reticulum stress and apoptosis-related protein CCAAT/enhancer- binding protein-homologous protein (CHOP/GADD153). Biochem J. 2003;369:643-50.
-
(2003)
Biochem J
, vol.369
, pp. 643-650
-
-
van der Sanden, M.H.M.1
Houweling, M.2
van Golde, L.M.3
Vaandrager, A.B.4
-
4
-
-
34547955231
-
Isolation and characterization of the Hamster gadd153 gene: Activation of promoter activity by agents that damage DNA
-
Luethy JD, Fargnoli J, Park JS, Fornace AJ Jr, Holbrooks NJ. Isolation and characterization of the Hamster gadd153 gene: activation of promoter activity by agents that damage DNA. Mol Cell Biol. 1989;9:4196-203.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 4196-4203
-
-
Luethy, J.D.1
Fargnoli, J.2
Park, J.S.3
Fornace Jr, A.J.4
Holbrooks, N.J.5
-
5
-
-
23444443039
-
CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest
-
Barone MV, Crozat A, Tabace A, Philipson L, Ron D. CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest. Genes Dev. 1994;8:453-64.
-
(1994)
Genes Dev
, vol.8
, pp. 453-464
-
-
Barone, M.V.1
Crozat, A.2
Tabace, A.3
Philipson, L.4
Ron, D.5
-
6
-
-
0030597160
-
Ectopic expression of CHOP (GADD 153) induces apoptosis in M1 myeloblastic leukemia cells
-
Matsumoto M, Minami M, Takeda K, Sakao Y, Akira S. Ectopic expression of CHOP (GADD 153) induces apoptosis in M1 myeloblastic leukemia cells. FEBS Lett. 1996;395:143-7.
-
(1996)
FEBS Lett
, vol.395
, pp. 143-147
-
-
Matsumoto, M.1
Minami, M.2
Takeda, K.3
Sakao, Y.4
Akira, S.5
-
7
-
-
8944259440
-
Signal from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153)
-
Wang X-Z, Lawson B, Brewer JW, et al. Signal from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). Mol Cell Biol. 1996;16:4273-80.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4273-4280
-
-
Wang, X.-Z.1
Lawson, B.2
Brewer, J.W.3
-
8
-
-
0026546365
-
-
Ron D, Habener JF. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Gene Dev. 1992;6:439-53.
-
Ron D, Habener JF. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Gene Dev. 1992;6:439-53.
-
-
-
-
9
-
-
0027172235
-
Regulation of the C/EBP-related gene gadd153 by glucose deprivation
-
Carlson SG, Fawcett TW, Bartlett JD, Bernie M, Holbrook NJ. Regulation of the C/EBP-related gene gadd153 by glucose deprivation. Mol Cel Biol. 1993;13:4736-44.
-
(1993)
Mol Cel Biol
, vol.13
, pp. 4736-4744
-
-
Carlson, S.G.1
Fawcett, T.W.2
Bartlett, J.D.3
Bernie, M.4
Holbrook, N.J.5
-
10
-
-
0029130373
-
Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153)
-
Batchvarova N, Wang X-Z, Ron D. Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153). EMBO J. 1995;14:4654-61.
-
(1995)
EMBO J
, vol.14
, pp. 4654-4661
-
-
Batchvarova, N.1
Wang, X.-Z.2
Ron, D.3
-
11
-
-
0032546811
-
Human translocation liposarcoma-CCAAT/enhancer binding protein (C/EBP) homologous protein (TLS-CHOP) oncoprotein prevents adipocyte differentiation by directly interfering with C/EBPβ function
-
Adelmant G, Gilbert JD, Freytag SO. Human translocation liposarcoma-CCAAT/enhancer binding protein (C/EBP) homologous protein (TLS-CHOP) oncoprotein prevents adipocyte differentiation by directly interfering with C/EBPβ function. J Biol Chem. 1998;273:15574-81.
-
(1998)
J Biol Chem
, vol.273
, pp. 15574-15581
-
-
Adelmant, G.1
Gilbert, J.D.2
Freytag, S.O.3
-
12
-
-
0033749370
-
-
Tang Q-Q, Lane MD. Role of C/EBP homologous protein (CHOP-10) in the programmed activation of CCAAT/enhancer-binding protein-ß during adipogenesis. Proc Natl Acad Sci U S A. 2000;97:12446-50.
-
Tang Q-Q, Lane MD. Role of C/EBP homologous protein (CHOP-10) in the programmed activation of CCAAT/enhancer-binding protein-ß during adipogenesis. Proc Natl Acad Sci U S A. 2000;97:12446-50.
-
-
-
-
13
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science. 2004;306:457-61.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
-
14
-
-
4644329647
-
Mitochondrial reactive oxygen species control the transcription factor CHOP-10/GADD153 and adipocyte differentiation: A mechanism for hypoxia-dependent effect
-
Carriere A, Carmona M-C, Fernandez Y, et al. Mitochondrial reactive oxygen species control the transcription factor CHOP-10/GADD153 and adipocyte differentiation: a mechanism for hypoxia-dependent effect. J Biol Chem. 2004;279:40462-9.
-
(2004)
J Biol Chem
, vol.279
, pp. 40462-40469
-
-
Carriere, A.1
Carmona, M.-C.2
Fernandez, Y.3
-
15
-
-
0035845568
-
Nitric oxide-induced apoptosis in pancreatic ß cells is mediated by the endoplasmic reticulum stress pathway
-
Oyadomari S, Takeda K, Takiguchi M, et al. Nitric oxide-induced apoptosis in pancreatic ß cells is mediated by the endoplasmic reticulum stress pathway. Proc Natl Acad Sci U S A. 2001;98:10845-50.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10845-10850
-
-
Oyadomari, S.1
Takeda, K.2
Takiguchi, M.3
-
16
-
-
0036175128
-
Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes
-
Oyadomari S, Koizumi A, Takeda K, et al. Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes. J Clin Invest. 2002;109:525-32.
-
(2002)
J Clin Invest
, vol.109
, pp. 525-532
-
-
Oyadomari, S.1
Koizumi, A.2
Takeda, K.3
-
17
-
-
0037144394
-
Increased beta-oxidation but no insulin resistance or glucose intolerance in mice lacking adiponectin
-
Ma K, Cabrero A, Saha PK, et al. Increased beta-oxidation but no insulin resistance or glucose intolerance in mice lacking adiponectin. J Biol Chem. 2002;277:34658-61.
-
(2002)
J Biol Chem
, vol.277
, pp. 34658-34661
-
-
Ma, K.1
Cabrero, A.2
Saha, P.K.3
-
18
-
-
26944442471
-
Molecular mechanisms associated with leptin resistance: N-3 polyunsaturated fatty acids induce alterations in the tight junction of the brain
-
Oh-I S, Shimizu H, Sato T, Uehara Y, Okada S, Mori M. Molecular mechanisms associated with leptin resistance: n-3 polyunsaturated fatty acids induce alterations in the tight junction of the brain. Cell Metab. 2005;1:331-41.
-
(2005)
Cell Metab
, vol.1
, pp. 331-341
-
-
Oh-I, S.1
Shimizu, H.2
Sato, T.3
Uehara, Y.4
Okada, S.5
Mori, M.6
-
19
-
-
29344460625
-
Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma
-
Tomaru T, Sato T, Yoshino S, et al. Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma. Endocrinology. 2006;147:377-88.
-
(2006)
Endocrinology
, vol.147
, pp. 377-388
-
-
Tomaru, T.1
Sato, T.2
Yoshino, S.3
-
20
-
-
0027741172
-
An increase of serum remnant-like particle in non-insulin dependent diabetic patients with microalbuminuria
-
Shimizu H, Saito T, Mori M. An increase of serum remnant-like particle in non-insulin dependent diabetic patients with microalbuminuria. Clin Chim Acta. 1993;221:191-6.
-
(1993)
Clin Chim Acta
, vol.221
, pp. 191-196
-
-
Shimizu, H.1
Saito, T.2
Mori, M.3
-
21
-
-
0024229140
-
Diet-induced type II diabetes in C57BL/6J mice
-
Surwit RS, Kuhn CM, Cochrane C, McCubbin JA, Feinglos MN. Diet-induced type II diabetes in C57BL/6J mice. Diabetes. 1988;37:1163-7.
-
(1988)
Diabetes
, vol.37
, pp. 1163-1167
-
-
Surwit, R.S.1
Kuhn, C.M.2
Cochrane, C.3
McCubbin, J.A.4
Feinglos, M.N.5
-
22
-
-
3843142823
-
Intrinsic heterogeneity in adipose tissue of fat-specific insulin receptor knock-out mice is associated with differences in patterns of gene expression
-
Bluher M, Patti ME, Gesta S, Kahn BB, Kahn CR. Intrinsic heterogeneity in adipose tissue of fat-specific insulin receptor knock-out mice is associated with differences in patterns of gene expression. J Biol Chem. 2004;279:31891-901.
-
(2004)
J Biol Chem
, vol.279
, pp. 31891-31901
-
-
Bluher, M.1
Patti, M.E.2
Gesta, S.3
Kahn, B.B.4
Kahn, C.R.5
-
23
-
-
0034640262
-
Increased insulin receptor substrate-1 and enhanced skeletal muscle insulin sensitivity in mice lacking CCAAT/enhancer-binding protein beta
-
Wang L, Shao X, Muhlenkamp P, et al. Increased insulin receptor substrate-1 and enhanced skeletal muscle insulin sensitivity in mice lacking CCAAT/enhancer-binding protein beta. J Biol Chem. 2000;275:4173-81.
-
(2000)
J Biol Chem
, vol.275
, pp. 4173-4181
-
-
Wang, L.1
Shao, X.2
Muhlenkamp, P.3
-
24
-
-
0027420920
-
A 30-kDa alternative translation product of the CCAAT/enhancer binding protein α message: Transcriptional activator lacking anti-mitotic activity
-
Lin F-T, MacDougald OA, Diehl AM, Lane MD. A 30-kDa alternative translation product of the CCAAT/enhancer binding protein α message: transcriptional activator lacking anti-mitotic activity. Proc Natl Acad Sci U S A. 1993;90:9606-10.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 9606-9610
-
-
Lin, F.-T.1
MacDougald, O.A.2
Diehl, A.M.3
Lane, M.D.4
-
25
-
-
0033869876
-
Translational control of C/EBPa and C/EBPß isoform expression
-
Calkhoven CF, Muller C, Leutz A. Translational control of C/EBPa and C/EBPß isoform expression. Gene & Dev. 2000;14:1920-32.
-
(2000)
Gene & Dev
, vol.14
, pp. 1920-1932
-
-
Calkhoven, C.F.1
Muller, C.2
Leutz, A.3
-
27
-
-
0030811942
-
Estrogen increases in vivo leptin production in rats and human subjects
-
Shimizu H, Shimomura Y, Nakanishi Y, et al. Estrogen increases in vivo leptin production in rats and human subjects. J Endocrinol. 1997;154:285-92.
-
(1997)
J Endocrinol
, vol.154
, pp. 285-292
-
-
Shimizu, H.1
Shimomura, Y.2
Nakanishi, Y.3
-
28
-
-
12944276957
-
Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity
-
Jones ME, Thorburn AW, Britt KL, et al. Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity. Proc Natl Acad Sci U S A. 2000;97:12735-740.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12735-12740
-
-
Jones, M.E.1
Thorburn, A.W.2
Britt, K.L.3
-
29
-
-
0033749264
-
Increased adipose tissue in male and female estrogen receptor-alpha knockout mice
-
Heine PA, Taylor JA, Iwamoto GA, Lubahn DB, Cooke PS. Increased adipose tissue in male and female estrogen receptor-alpha knockout mice. Proc Natl Acad Sci U S A. 2000;97:12729-34.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12729-12734
-
-
Heine, P.A.1
Taylor, J.A.2
Iwamoto, G.A.3
Lubahn, D.B.4
Cooke, P.S.5
-
30
-
-
0017129654
-
Sex differences in sensitivity of food intake, body weight, and running-wheel activity to ovarian steroids in rats
-
Gentry RT, Wade GN. Sex differences in sensitivity of food intake, body weight, and running-wheel activity to ovarian steroids in rats. J Comp Physiol Psychol. 1976;90:747-54.
-
(1976)
J Comp Physiol Psychol
, vol.90
, pp. 747-754
-
-
Gentry, R.T.1
Wade, G.N.2
-
31
-
-
2942586971
-
Target of 17ß-estradiol-induced apoptosis in colon cancer cells: A mechanism for the protective effects of hormone replacement therapy?
-
Qiu Y, Langman MJS, Eggo MC. Target of 17ß-estradiol-induced apoptosis in colon cancer cells: a mechanism for the protective effects of hormone replacement therapy? J Endocrinol. 2004;181:327-37.
-
(2004)
J Endocrinol
, vol.181
, pp. 327-337
-
-
Qiu, Y.1
Langman, M.J.S.2
Eggo, M.C.3
|