Chronic oxidative stress as a mechanism for glucose toxicity of the beta cell in type 2 diabetes

Cell Biochemistry and Biophysics

Volumn 48, Issue 2-3, 2007, Pages 139-146

  Robertson, R ^a   Zhou, Huarong ^a   Zhang, Tao ^a   Harmon, Jamie S ^a  

^a PACIFIC NORTHWEST RESEARCH INSTITUTE   (United States)

Author keywords

Beta cell; Glucose toxicity; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; GLUCOSE; GLUTATHIONE PEROXIDASE; GLYCERALDEHYDE; HOMEODOMAIN PROTEIN; INSULIN; INSULIN PROMOTER FACTOR 1; INTERLEUKIN 1BETA; REACTIVE OXYGEN METABOLITE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR MAF; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; BLOOD; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; HYPERLIPIDEMIA; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY; PHYSIOLOGY;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; DIABETES MELLITUS, TYPE 2; GENE EXPRESSION; GLUCOSE; GLUTATHIONE PEROXIDASE; GLYCERALDEHYDE; HOMEODOMAIN PROTEINS; HYPERLIPIDEMIAS; INSULIN; INSULIN-SECRETING CELLS; INTERLEUKIN-1BETA; MAF TRANSCRIPTION FACTORS, LARGE; MODELS, BIOLOGICAL; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TRANS-ACTIVATORS; TRANSFECTION;

ANIMALIA;

EID: 34548317416     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-007-0026-5     Document Type: Article

References (40)

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