-
2
-
-
0034467738
-
The human interferon alpha species and receptors
-
Pestka S. The human interferon alpha species and receptors. Biopolymers 55 (2000) 254-287
-
(2000)
Biopolymers
, vol.55
, pp. 254-287
-
-
Pestka, S.1
-
3
-
-
0022919476
-
Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region
-
Levy D., Larner A., Chaudhuri A., Babiss L.E., and Darnell Jr. J.E. Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region. Proc Natl Acad Sci USA 83 (1986) 8929-8933
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 8929-8933
-
-
Levy, D.1
Larner, A.2
Chaudhuri, A.3
Babiss, L.E.4
Darnell Jr., J.E.5
-
4
-
-
0342535752
-
Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element
-
Reich N., Evans B., Levy D., Fahey D., Knight Jr. E., and Darnell Jr. J.E. Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc Natl Acad Sci USA 84 (1987) 6394-6398
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 6394-6398
-
-
Reich, N.1
Evans, B.2
Levy, D.3
Fahey, D.4
Knight Jr., E.5
Darnell Jr., J.E.6
-
5
-
-
0026686488
-
The proteins of ISGF-3, the IFN-α induced transcription activator, define a new family of signal transducers
-
Fu X.-Y., Schindler C., Improta T., Aebersold R., and Darnell J.E. The proteins of ISGF-3, the IFN-α induced transcription activator, define a new family of signal transducers. Proc Natl Acad Sci USA 89 (1992) 7840-7843
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7840-7843
-
-
Fu, X.-Y.1
Schindler, C.2
Improta, T.3
Aebersold, R.4
Darnell, J.E.5
-
6
-
-
2842610984
-
Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes
-
Kessler D.S., Levy D.E., and Darnell Jr. J.E. Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes. Proc Natl Acad Sci USA 85 (1988) 8521-8525
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 8521-8525
-
-
Kessler, D.S.1
Levy, D.E.2
Darnell Jr., J.E.3
-
7
-
-
0026725868
-
Proteins of transcription factor ISGF-3: one gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon alpha
-
Schindler C., Fu X.Y., Improta T., Aebersold R., and Darnell Jr. J.E. Proteins of transcription factor ISGF-3: one gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon alpha. Proc Natl Acad Sci USA 89 (1992) 7836-7839
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7836-7839
-
-
Schindler, C.1
Fu, X.Y.2
Improta, T.3
Aebersold, R.4
Darnell Jr., J.E.5
-
8
-
-
0026770248
-
Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
-
Schindler C., Shuai K., Prezioso V.R., and Darnell Jr. J.E. Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 257 (1992) 809-813
-
(1992)
Science
, vol.257
, pp. 809-813
-
-
Schindler, C.1
Shuai, K.2
Prezioso, V.R.3
Darnell Jr., J.E.4
-
9
-
-
0027090310
-
Activation of transcription by IFN-γ: tyrosine phosphorylation of a 91-kDa DNA binding protein
-
Shuai K., Schindler C., Prezioso V., and Darnell J.E. Activation of transcription by IFN-γ: tyrosine phosphorylation of a 91-kDa DNA binding protein. Science 258 (1992) 1808-1812
-
(1992)
Science
, vol.258
, pp. 1808-1812
-
-
Shuai, K.1
Schindler, C.2
Prezioso, V.3
Darnell, J.E.4
-
10
-
-
0026632288
-
A protein tyrosine kinase in the interferon alpha/beta signaling pathway
-
Velazquez L., Fellous M., Stark G.R., and Pellegrini S. A protein tyrosine kinase in the interferon alpha/beta signaling pathway. Cell 70 (1992) 313-322
-
(1992)
Cell
, vol.70
, pp. 313-322
-
-
Velazquez, L.1
Fellous, M.2
Stark, G.R.3
Pellegrini, S.4
-
11
-
-
0036731485
-
Stats: transcriptional control and biological impact
-
Levy D.E., and Darnell Jr. J.E. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 3 (2002) 651-662
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell Jr., J.E.2
-
12
-
-
25444495693
-
The yin and yang of type I interferon activity in bacterial infection
-
Decker T., Muller M., and Stockinger S. The yin and yang of type I interferon activity in bacterial infection. Nat Rev Immunol 5 (2005) 675-687
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 675-687
-
-
Decker, T.1
Muller, M.2
Stockinger, S.3
-
13
-
-
0036233585
-
Cytokine signaling in 2002: new surprises in the Jak/Stat pathway
-
O'Shea J.J., Gadina M., and Schreiber R.D. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 109 Suppl (2002) S121-S131
-
(2002)
Cell
, vol.109
, Issue.SUPPL
-
-
O'Shea, J.J.1
Gadina, M.2
Schreiber, R.D.3
-
14
-
-
2542478996
-
The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response
-
Alexander W.S., and Hilton D.J. The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. Annu Rev Immunol 22 (2004) 503-529
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 503-529
-
-
Alexander, W.S.1
Hilton, D.J.2
-
15
-
-
0024147529
-
Transcriptional regulation of interferon-stimulated genes: a DNA response element and induced proteins that recognize it
-
Levy D., Reich N., Kessler D., Pine R., and Darnell Jr. J.E. Transcriptional regulation of interferon-stimulated genes: a DNA response element and induced proteins that recognize it. Cold Spring Harb Symp Quant Biol 53 Pt 2 (1988) 799-802
-
(1988)
Cold Spring Harb Symp Quant Biol
, vol.53
, Issue.PART 2
, pp. 799-802
-
-
Levy, D.1
Reich, N.2
Kessler, D.3
Pine, R.4
Darnell Jr., J.E.5
-
16
-
-
0025172081
-
ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains
-
Fu X.Y., Kessler D.S., Veals S.A., Levy D.E., and Darnell Jr. J.E. ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains. Proc Natl Acad Sci USA 87 (1990) 8555-8559
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 8555-8559
-
-
Fu, X.Y.1
Kessler, D.S.2
Veals, S.A.3
Levy, D.E.4
Darnell Jr., J.E.5
-
17
-
-
0024721567
-
Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro
-
Levy D.E., Kessler D.S., Pine R., and Darnell Jr. J.E. Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro. Genes Dev 3 (1989) 1362-1371
-
(1989)
Genes Dev
, vol.3
, pp. 1362-1371
-
-
Levy, D.E.1
Kessler, D.S.2
Pine, R.3
Darnell Jr., J.E.4
-
18
-
-
0026778338
-
Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins
-
Veals S.A., Schindler C., Leonard D., Fu X.Y., Aebersold R., Darnell Jr. J.E., et al. Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins. Mol Cell Biol 12 (1992) 3315-3324
-
(1992)
Mol Cell Biol
, vol.12
, pp. 3315-3324
-
-
Veals, S.A.1
Schindler, C.2
Leonard, D.3
Fu, X.Y.4
Aebersold, R.5
Darnell Jr., J.E.6
-
19
-
-
0027090310
-
Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein
-
Shuai K., Schindler C., Prezioso V.R., and Darnell Jr. J.E. Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein. Science 258 (1992) 1808-1812
-
(1992)
Science
, vol.258
, pp. 1808-1812
-
-
Shuai, K.1
Schindler, C.2
Prezioso, V.R.3
Darnell Jr., J.E.4
-
20
-
-
0026069531
-
Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons
-
Lew D.J., Decker T., Strehlow I., and Darnell J.E. Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons. Mol Cell Biol 11 (1991) 182-191
-
(1991)
Mol Cell Biol
, vol.11
, pp. 182-191
-
-
Lew, D.J.1
Decker, T.2
Strehlow, I.3
Darnell, J.E.4
-
21
-
-
0027240840
-
The response of gamma interferon activation factor is under developmental control in cells of the macrophage lineage
-
Eilers A., Seegert D., Schindler C., Baccarini M., and Decker T. The response of gamma interferon activation factor is under developmental control in cells of the macrophage lineage. Mol Cell Biol 13 (1993) 3245-3254
-
(1993)
Mol Cell Biol
, vol.13
, pp. 3245-3254
-
-
Eilers, A.1
Seegert, D.2
Schindler, C.3
Baccarini, M.4
Decker, T.5
-
22
-
-
0027159217
-
The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds
-
Kanno Y., Kozak C.A., Schindler C., Driggers P.H., Ennist D.L., Gleason S.L., et al. The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds. Mol Cell Biol 13 (1993) 3951-3963
-
(1993)
Mol Cell Biol
, vol.13
, pp. 3951-3963
-
-
Kanno, Y.1
Kozak, C.A.2
Schindler, C.3
Driggers, P.H.4
Ennist, D.L.5
Gleason, S.L.6
-
23
-
-
0027151991
-
Interferon gamma-induced transcription of the high-affinity Fc receptor for IgG requires assembly of a complex that includes the 91-kDa subunit of transcription factor ISGF3
-
Pearse R.N., Feinman R., Shuai K., Darnell Jr. J.E., and Ravetch J.V. Interferon gamma-induced transcription of the high-affinity Fc receptor for IgG requires assembly of a complex that includes the 91-kDa subunit of transcription factor ISGF3. Proc Natl Acad Sci USA 90 (1993) 4314-4318
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4314-4318
-
-
Pearse, R.N.1
Feinman, R.2
Shuai, K.3
Darnell Jr., J.E.4
Ravetch, J.V.5
-
24
-
-
0032499801
-
Three-dimensional structure of the Stat3beta homodimer bound to DNA
-
Becker S., Groner B., and Muller C.W. Three-dimensional structure of the Stat3beta homodimer bound to DNA. Nature 394 (1998) 145-151
-
(1998)
Nature
, vol.394
, pp. 145-151
-
-
Becker, S.1
Groner, B.2
Muller, C.W.3
-
25
-
-
0032577678
-
Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
-
Chen X., Vinkemeier U., Zhao Y., Jeruzalmi D., Darnell Jr. J.E., and Kuriyan J. Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell 93 (1998) 827-839
-
(1998)
Cell
, vol.93
, pp. 827-839
-
-
Chen, X.1
Vinkemeier, U.2
Zhao, Y.3
Jeruzalmi, D.4
Darnell Jr., J.E.5
Kuriyan, J.6
-
26
-
-
0032525251
-
Human CD34(+) bone marrow cells regulate stromal production of interleukin-6 and granulocyte colony-stimulating factor and increase the colony-stimulating activity of stroma
-
Gupta P., Blazar B.R., Gupta K., and Verfaillie C.M. Human CD34(+) bone marrow cells regulate stromal production of interleukin-6 and granulocyte colony-stimulating factor and increase the colony-stimulating activity of stroma. Blood 91 (1998) 3724-3733
-
(1998)
Blood
, vol.91
, pp. 3724-3733
-
-
Gupta, P.1
Blazar, B.R.2
Gupta, K.3
Verfaillie, C.M.4
-
27
-
-
0028349904
-
Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
-
Shuai K., Horvath C.M., Huang L.H., Qureshi S.A., Cowburn D., and Darnell Jr. J.E. Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. Cell 76 (1994) 821-828
-
(1994)
Cell
, vol.76
, pp. 821-828
-
-
Shuai, K.1
Horvath, C.M.2
Huang, L.H.3
Qureshi, S.A.4
Cowburn, D.5
Darnell Jr., J.E.6
-
28
-
-
0024989359
-
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
-
Firmbach-Kraft I., Byers M., Shows T., Dalla-Favera R., and Krolewski J.J. tyk2, prototype of a novel class of non-receptor tyrosine kinase genes. Oncogene 5 (1990) 1329-1336
-
(1990)
Oncogene
, vol.5
, pp. 1329-1336
-
-
Firmbach-Kraft, I.1
Byers, M.2
Shows, T.3
Dalla-Favera, R.4
Krolewski, J.J.5
-
29
-
-
0026081302
-
Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase
-
Wilks A.F., Harpur A.G., Kurban R.R., Ralph S.J., Zurcher G., and Ziemiecki A. Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase. Mol Cell Biol 11 (1991) 2057-2065
-
(1991)
Mol Cell Biol
, vol.11
, pp. 2057-2065
-
-
Wilks, A.F.1
Harpur, A.G.2
Kurban, R.R.3
Ralph, S.J.4
Zurcher, G.5
Ziemiecki, A.6
-
30
-
-
0027742729
-
Interferon-induced nuclear signalling by Jak protein tyrosine kinases
-
Silvennoinen O., Ihle J.N., Schlessinger J., and Levy D.E. Interferon-induced nuclear signalling by Jak protein tyrosine kinases. Nature 366 (1993) 583-585
-
(1993)
Nature
, vol.366
, pp. 583-585
-
-
Silvennoinen, O.1
Ihle, J.N.2
Schlessinger, J.3
Levy, D.E.4
-
31
-
-
0027914818
-
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway
-
Watling D., Guschin D., Muller M., Silvennoinen O., Witthuhn B.A., Quelle F.W., et al. Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway. Nature 366 (1993) 166-170
-
(1993)
Nature
, vol.366
, pp. 166-170
-
-
Watling, D.1
Guschin, D.2
Muller, M.3
Silvennoinen, O.4
Witthuhn, B.A.5
Quelle, F.W.6
-
32
-
-
0027179365
-
Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase
-
Argetsinger L.S., Campbell G.S., Yang X., Witthuhn B.A., Silvennoinen O., Ihle J.N., et al. Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase. Cell 74 (1993) 237-244
-
(1993)
Cell
, vol.74
, pp. 237-244
-
-
Argetsinger, L.S.1
Campbell, G.S.2
Yang, X.3
Witthuhn, B.A.4
Silvennoinen, O.5
Ihle, J.N.6
-
33
-
-
0027494653
-
The protein tyrosine kinase JAK1 complements defects in interferon- alpha/beta and -gamma signal transduction
-
Müller M., Briscoe J., Laxton C., Guschin D., Ziemiecki A., Silvennoinen O., et al. The protein tyrosine kinase JAK1 complements defects in interferon- alpha/beta and -gamma signal transduction. Nature 366 (1993) 129-135
-
(1993)
Nature
, vol.366
, pp. 129-135
-
-
Müller, M.1
Briscoe, J.2
Laxton, C.3
Guschin, D.4
Ziemiecki, A.5
Silvennoinen, O.6
-
34
-
-
0027771191
-
Characterization of a pathway for ciliary neurotrophic factor signaling to the nucleus
-
Bonni A., Frank D.A., Schindler C., and Greenberg M.E. Characterization of a pathway for ciliary neurotrophic factor signaling to the nucleus. Science 262 (1993) 1575-1579
-
(1993)
Science
, vol.262
, pp. 1575-1579
-
-
Bonni, A.1
Frank, D.A.2
Schindler, C.3
Greenberg, M.E.4
-
35
-
-
0028303977
-
Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
-
Akira S., Nishio Y., Inoue M., Wang X.J., Wei S., Matsusaka T., et al. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 77 (1994) 63-71
-
(1994)
Cell
, vol.77
, pp. 63-71
-
-
Akira, S.1
Nishio, Y.2
Inoue, M.3
Wang, X.J.4
Wei, S.5
Matsusaka, T.6
-
36
-
-
0028228543
-
Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation
-
Yamamoto K., Quelle F.W., Thierfelder W.E., Kreider B.L., Gilbert D.J., Jenkins N.A., et al. Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation. Mol Cell Biol 14 (1994) 4342-4349
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4342-4349
-
-
Yamamoto, K.1
Quelle, F.W.2
Thierfelder, W.E.3
Kreider, B.L.4
Gilbert, D.J.5
Jenkins, N.A.6
-
37
-
-
0028284762
-
Stat3 and Stat4: members of the family of signal transducers and activators of transcription
-
Zhong Z., Wen Z., and Darnell Jr. J.E. Stat3 and Stat4: members of the family of signal transducers and activators of transcription. Proc Natl Acad Sci USA 91 (1994) 4806-4810
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4806-4810
-
-
Zhong, Z.1
Wen, Z.2
Darnell Jr., J.E.3
-
38
-
-
0028262965
-
STF-IL4: a novel IL-4 induced signal transducing factor
-
Schindler C., Kashleva H., Pernis A., Pine R., and Rothman P. STF-IL4: a novel IL-4 induced signal transducing factor. EMBO J 13 (1994) 1350-1356
-
(1994)
EMBO J
, vol.13
, pp. 1350-1356
-
-
Schindler, C.1
Kashleva, H.2
Pernis, A.3
Pine, R.4
Rothman, P.5
-
39
-
-
0027972046
-
An interleukin-4-induced transcription factor: IL-4 Stat
-
Hou J., Schindler U., Henzel W.J., Ho T.C., Brasseur M., and McKnight S.L. An interleukin-4-induced transcription factor: IL-4 Stat. Science 265 (1994) 1701-1706
-
(1994)
Science
, vol.265
, pp. 1701-1706
-
-
Hou, J.1
Schindler, U.2
Henzel, W.J.3
Ho, T.C.4
Brasseur, M.5
McKnight, S.L.6
-
40
-
-
0028916417
-
Interleukin-3 signals through multiple isoforms of Stat5
-
Azam M., Erdjument-Bromage H., Kreider B.L., Xia M., Quelle F., Basu R., et al. Interleukin-3 signals through multiple isoforms of Stat5. EMBO J 14 (1995) 1402-1411
-
(1995)
EMBO J
, vol.14
, pp. 1402-1411
-
-
Azam, M.1
Erdjument-Bromage, H.2
Kreider, B.L.3
Xia, M.4
Quelle, F.5
Basu, R.6
-
41
-
-
0028963550
-
Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs
-
Mui A.L., Wakao H., O'Farrell A.M., Harada N., and Miyajima A. Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs. EMBO J 14 (1995) 1166-1175
-
(1995)
EMBO J
, vol.14
, pp. 1166-1175
-
-
Mui, A.L.1
Wakao, H.2
O'Farrell, A.M.3
Harada, N.4
Miyajima, A.5
-
42
-
-
0028217452
-
Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response
-
Wakao H., Gouilleux F., and Groner B. Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response. EMBO J 13 (1994) 2182-2191
-
(1994)
EMBO J
, vol.13
, pp. 2182-2191
-
-
Wakao, H.1
Gouilleux, F.2
Groner, B.3
-
43
-
-
0028301958
-
Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes
-
Kawamura M., McVicar D.W., Johnston J.A., Blake T.B., Chen Y.Q., Lal B.K., et al. Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes. Proc Natl Acad Sci USA 91 (1994) 6374-6378
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6374-6378
-
-
Kawamura, M.1
McVicar, D.W.2
Johnston, J.A.3
Blake, T.B.4
Chen, Y.Q.5
Lal, B.K.6
-
44
-
-
0037243222
-
IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex
-
Kotenko S.V., Gallagher G., Baurin V.V., Lewis-Antes A., Shen M., Shah N.K., et al. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat Immunol 4 (2003) 69-77
-
(2003)
Nat Immunol
, vol.4
, pp. 69-77
-
-
Kotenko, S.V.1
Gallagher, G.2
Baurin, V.V.3
Lewis-Antes, A.4
Shen, M.5
Shah, N.K.6
-
45
-
-
0037236826
-
IL-28, IL-29 and their class II cytokine receptor IL-28R
-
Sheppard P., Kindsvogel W., Xu W., Henderson K., Schlutsmeyer S., Whitmore T.E., et al. IL-28, IL-29 and their class II cytokine receptor IL-28R. Nat Immunol 4 (2003) 63-68
-
(2003)
Nat Immunol
, vol.4
, pp. 63-68
-
-
Sheppard, P.1
Kindsvogel, W.2
Xu, W.3
Henderson, K.4
Schlutsmeyer, S.5
Whitmore, T.E.6
-
46
-
-
34547108380
-
JAK-STAT signaling: from interferons to cytokines
-
Schindler C., Levy D.E., and Decker T. JAK-STAT signaling: from interferons to cytokines. J Biol Chem 282 (2007) 20059-20063
-
(2007)
J Biol Chem
, vol.282
, pp. 20059-20063
-
-
Schindler, C.1
Levy, D.E.2
Decker, T.3
-
47
-
-
33847351136
-
The JAK-STAT signaling pathway: input and output integration
-
Murray P.J. The JAK-STAT signaling pathway: input and output integration. J Immunol 178 (2007) 2623-2629
-
(2007)
J Immunol
, vol.178
, pp. 2623-2629
-
-
Murray, P.J.1
-
48
-
-
0032076183
-
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
-
Rodig S.J., Meraz M.A., White J.M., Lampe P.A., Riley J.K., Arthur C.D., et al. Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell 93 (1998) 373-383
-
(1998)
Cell
, vol.93
, pp. 373-383
-
-
Rodig, S.J.1
Meraz, M.A.2
White, J.M.3
Lampe, P.A.4
Riley, J.K.5
Arthur, C.D.6
-
49
-
-
18244432009
-
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
-
Neubauer H., Cumano A., Mueller M., Wu H., Huffstadt U., and Pfeffer K. Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell 93 (1998) 397-409
-
(1998)
Cell
, vol.93
, pp. 397-409
-
-
Neubauer, H.1
Cumano, A.2
Mueller, M.3
Wu, H.4
Huffstadt, U.5
Pfeffer, K.6
-
50
-
-
0032076542
-
Jak2 is essential for signaling through a variety of cytokine receptors
-
Parganas E., Wang D., Stravopodis D., Topham D.J., Marine J.C., Teglund S., et al. Jak2 is essential for signaling through a variety of cytokine receptors. Cell 93 (1998) 385-395
-
(1998)
Cell
, vol.93
, pp. 385-395
-
-
Parganas, E.1
Wang, D.2
Stravopodis, D.3
Topham, D.J.4
Marine, J.C.5
Teglund, S.6
-
51
-
-
39749198165
-
JAK and MPL mutations in myeloid malignancies
-
Tefferi A. JAK and MPL mutations in myeloid malignancies. Leuk Lymphoma 49 (2008) 388-397
-
(2008)
Leuk Lymphoma
, vol.49
, pp. 388-397
-
-
Tefferi, A.1
-
52
-
-
0028840706
-
Defective lymphoid development in mice lacking Jak3
-
Nosaka T., vanDeursen J.M., Tripp R.A., Thierfelder W.E., Witthuhn B.A., McMickle A.P., et al. Defective lymphoid development in mice lacking Jak3. Science 270 (1995) 800-802
-
(1995)
Science
, vol.270
, pp. 800-802
-
-
Nosaka, T.1
vanDeursen, J.M.2
Tripp, R.A.3
Thierfelder, W.E.4
Witthuhn, B.A.5
McMickle, A.P.6
-
53
-
-
0029550822
-
Developmental defects of lymphoid cells in Jak3 kinase-deficient mice
-
Park S.Y., Saijo K., Takahashi T., Osawa M., Arase H., Hirayama N., et al. Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity 3 (1995) 771-782
-
(1995)
Immunity
, vol.3
, pp. 771-782
-
-
Park, S.Y.1
Saijo, K.2
Takahashi, T.3
Osawa, M.4
Arase, H.5
Hirayama, N.6
-
54
-
-
0028799457
-
Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3
-
Thomis D.C., Gurniak C.B., Tivol E., Sharpe A.H., and Berg L.J. Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3. Science 270 (1995) 794-797
-
(1995)
Science
, vol.270
, pp. 794-797
-
-
Thomis, D.C.1
Gurniak, C.B.2
Tivol, E.3
Sharpe, A.H.4
Berg, L.J.5
-
55
-
-
0037438351
-
Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice
-
Seto Y., Nakajima H., Suto A., Shimoda K., Saito Y., Nakayama K.I., et al. Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice. J Immunol 170 (2003) 1077-1083
-
(2003)
J Immunol
, vol.170
, pp. 1077-1083
-
-
Seto, Y.1
Nakajima, H.2
Suto, A.3
Shimoda, K.4
Saito, Y.5
Nakayama, K.I.6
-
56
-
-
0033696404
-
Partial impairment of cytokine responses in Tyk2-deficient mice
-
Karaghiosoff M., Neubauer H., Lassnig C., Kovarik P., Schindler H., Pircher H., et al. Partial impairment of cytokine responses in Tyk2-deficient mice. Immunity 13 (2000) 549-560
-
(2000)
Immunity
, vol.13
, pp. 549-560
-
-
Karaghiosoff, M.1
Neubauer, H.2
Lassnig, C.3
Kovarik, P.4
Schindler, H.5
Pircher, H.6
-
57
-
-
0033711641
-
Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function
-
Shimoda K., Kato K., Aoki K., Matsuda T., Miyamoto A., Shibamori M., et al. Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function. Immunity 13 (2000) 561-571
-
(2000)
Immunity
, vol.13
, pp. 561-571
-
-
Shimoda, K.1
Kato, K.2
Aoki, K.3
Matsuda, T.4
Miyamoto, A.5
Shibamori, M.6
-
58
-
-
33845897463
-
Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity
-
Minegishi Y., Saito M., Morio T., Watanabe K., Agematsu K., Tsuchiya S., et al. Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity 25 (2006) 745-755
-
(2006)
Immunity
, vol.25
, pp. 745-755
-
-
Minegishi, Y.1
Saito, M.2
Morio, T.3
Watanabe, K.4
Agematsu, K.5
Tsuchiya, S.6
-
59
-
-
0038476601
-
Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock
-
Karaghiosoff M., Steinborn R., Kovarik P., Kriegshauser G., Baccarini M., Donabauer B., et al. Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock. Nat Immunol 4 (2003) 471-477
-
(2003)
Nat Immunol
, vol.4
, pp. 471-477
-
-
Karaghiosoff, M.1
Steinborn, R.2
Kovarik, P.3
Kriegshauser, G.4
Baccarini, M.5
Donabauer, B.6
-
60
-
-
0037138370
-
Signaling through the JAK/STAT pathway, recent advances and future challenges
-
Kisseleva T., Bhattacharya S., Braunstein J., and Schindler C.W. Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 285 (2002) 1-24
-
(2002)
Gene
, vol.285
, pp. 1-24
-
-
Kisseleva, T.1
Bhattacharya, S.2
Braunstein, J.3
Schindler, C.W.4
-
61
-
-
0035862542
-
Structure of the mouse stat 3/5 locus: evolution from drosophila to zebrafish to mouse
-
Miyoshi K., Cui Y., Riedlinger G., Lehoczky J., Zon L., Oka T., et al. Structure of the mouse stat 3/5 locus: evolution from drosophila to zebrafish to mouse. Genomics 71 (2001) 150-155
-
(2001)
Genomics
, vol.71
, pp. 150-155
-
-
Miyoshi, K.1
Cui, Y.2
Riedlinger, G.3
Lehoczky, J.4
Zon, L.5
Oka, T.6
-
62
-
-
28844472292
-
Structure of the unphosphorylated STAT5a dimer
-
Neculai D., Neculai A.M., Verrier S., Straub K., Klumpp K., Pfitzner E., et al. Structure of the unphosphorylated STAT5a dimer. J Biol Chem 280 (2005) 40782-40787
-
(2005)
J Biol Chem
, vol.280
, pp. 40782-40787
-
-
Neculai, D.1
Neculai, A.M.2
Verrier, S.3
Straub, K.4
Klumpp, K.5
Pfitzner, E.6
-
63
-
-
20144376462
-
Structural bases of unphosphorylated STAT1 association and receptor binding
-
Mao X., Ren Z., Parker G.N., Sondermann H., Pastorello M.A., Wang W., et al. Structural bases of unphosphorylated STAT1 association and receptor binding. Mol Cell 17 (2005) 761-771
-
(2005)
Mol Cell
, vol.17
, pp. 761-771
-
-
Mao, X.1
Ren, Z.2
Parker, G.N.3
Sondermann, H.4
Pastorello, M.A.5
Wang, W.6
-
64
-
-
33845718240
-
Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain
-
Mertens C., Zhong M., Krishnaraj R., Zou W., Chen X., and Darnell Jr. J.E. Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain. Genes Dev 20 (2006) 3372-3381
-
(2006)
Genes Dev
, vol.20
, pp. 3372-3381
-
-
Mertens, C.1
Zhong, M.2
Krishnaraj, R.3
Zou, W.4
Chen, X.5
Darnell Jr., J.E.6
-
65
-
-
20144367694
-
Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle
-
Zhong M., Henriksen M.A., Takeuchi K., Schaefer O., Liu B., ten Hoeve J., et al. Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle. Proc Natl Acad Sci USA 102 (2005) 3966-3971
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 3966-3971
-
-
Zhong, M.1
Henriksen, M.A.2
Takeuchi, K.3
Schaefer, O.4
Liu, B.5
ten Hoeve, J.6
-
67
-
-
0042977521
-
The ins and outs of STAT1 nuclear transport
-
McBride K.M., and Reich N.C. The ins and outs of STAT1 nuclear transport. Sci STKE 2003 (2003) RE13
-
(2003)
Sci STKE
, vol.2003
-
-
McBride, K.M.1
Reich, N.C.2
-
68
-
-
0041660942
-
DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1
-
Meyer T., Marg A., Lemke P., Wiesner B., and Vinkemeier U. DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1. Genes Dev 17 (2003) 1992-2005
-
(2003)
Genes Dev
, vol.17
, pp. 1992-2005
-
-
Meyer, T.1
Marg, A.2
Lemke, P.3
Wiesner, B.4
Vinkemeier, U.5
-
69
-
-
0037327154
-
Regulation of Stat3 nuclear export
-
Bhattacharya S., and Schindler C. Regulation of Stat3 nuclear export. J Clin Invest 111 (2003) 553-559
-
(2003)
J Clin Invest
, vol.111
, pp. 553-559
-
-
Bhattacharya, S.1
Schindler, C.2
-
70
-
-
0033230707
-
Murine Stat2 is uncharacteristically divergent
-
Park C., Lecomte M.J., and Schindler C. Murine Stat2 is uncharacteristically divergent. Nucleic Acids Res 27 (1999) 4191-4199
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 4191-4199
-
-
Park, C.1
Lecomte, M.J.2
Schindler, C.3
-
71
-
-
84882837001
-
Regulation of Stats by posttranslational modification
-
Seghal P.B., Hirano T., and Levy D.E. (Eds), Kluwer Academic
-
Decker T., Müller M., and Kovarik P. Regulation of Stats by posttranslational modification. In: Seghal P.B., Hirano T., and Levy D.E. (Eds). Signal transducers and activators of transcription (Stats): activation and biology (2003), Kluwer Academic
-
(2003)
Signal transducers and activators of transcription (Stats): activation and biology
-
-
Decker, T.1
Müller, M.2
Kovarik, P.3
-
72
-
-
33847271713
-
Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-{gamma}-inducible gbp2 gene
-
Ramsauer K., Farlik M., Zupkovitz G., Seiser C., Kroger A., Hauser H., et al. Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-{gamma}-inducible gbp2 gene. Proc Natl Acad Sci USA 104 (2007) 2849-2854
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 2849-2854
-
-
Ramsauer, K.1
Farlik, M.2
Zupkovitz, G.3
Seiser, C.4
Kroger, A.5
Hauser, H.6
-
73
-
-
0037184052
-
An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1
-
Litterst C.M., and Pfitzner E. An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1. J Biol Chem 277 (2002) 36052-36060
-
(2002)
J Biol Chem
, vol.277
, pp. 36052-36060
-
-
Litterst, C.M.1
Pfitzner, E.2
-
74
-
-
0037040924
-
Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a
-
Giraud S., Bienvenu F., Avril S., Gascan H., Heery D.M., and Coqueret O. Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a. J Biol Chem 277 (2002) 8004-8011
-
(2002)
J Biol Chem
, vol.277
, pp. 8004-8011
-
-
Giraud, S.1
Bienvenu, F.2
Avril, S.3
Gascan, H.4
Heery, D.M.5
Coqueret, O.6
-
75
-
-
0036170183
-
IFN-Stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff
-
Paulson M., Press C., Smith E., Tanese N., and Levy D.E. IFN-Stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff. Nat Cell Biol 4 (2002) 140-147
-
(2002)
Nat Cell Biol
, vol.4
, pp. 140-147
-
-
Paulson, M.1
Press, C.2
Smith, E.3
Tanese, N.4
Levy, D.E.5
-
76
-
-
33947177232
-
Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rbeta2 expression during human Th1 cell differentiation
-
Letimier F.A., Passini N., Gasparian S., Bianchi E., and Rogge L. Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rbeta2 expression during human Th1 cell differentiation. EMBO J 26 (2007) 1292-1302
-
(2007)
EMBO J
, vol.26
, pp. 1292-1302
-
-
Letimier, F.A.1
Passini, N.2
Gasparian, S.3
Bianchi, E.4
Rogge, L.5
-
77
-
-
0037090777
-
Interferon-gamma-induced chromatin remodeling at the CIITA locus is BRG1 dependent
-
Pattenden S.G., Klose R., Karaskov E., and Bremner R. Interferon-gamma-induced chromatin remodeling at the CIITA locus is BRG1 dependent. EMBO J 21 (2002) 1978-1986
-
(2002)
EMBO J
, vol.21
, pp. 1978-1986
-
-
Pattenden, S.G.1
Klose, R.2
Karaskov, E.3
Bremner, R.4
-
78
-
-
0036723647
-
Maximal induction of a subset of interferon target genes requires the chromatin-remodeling activity of the BAF complex
-
Liu H., Kang H., Liu R., Chen X., and Zhao K. Maximal induction of a subset of interferon target genes requires the chromatin-remodeling activity of the BAF complex. Mol Cell Biol 22 (2002) 6471-6479
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6471-6479
-
-
Liu, H.1
Kang, H.2
Liu, R.3
Chen, X.4
Zhao, K.5
-
79
-
-
0036800352
-
Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes
-
Huang M., Qian F., Hu Y., Ang C., Li Z., and Wen Z. Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes. Nat Cell Biol 4 (2002) 774-781
-
(2002)
Nat Cell Biol
, vol.4
, pp. 774-781
-
-
Huang, M.1
Qian, F.2
Hu, Y.3
Ang, C.4
Li, Z.5
Wen, Z.6
-
80
-
-
30344447505
-
Unexpected roles for deacetylation in interferon- and cytokine-induced transcription
-
Nusinzon I., and Horvath C.M. Unexpected roles for deacetylation in interferon- and cytokine-induced transcription. J Interferon Cytokine Res 25 (2005) 745-748
-
(2005)
J Interferon Cytokine Res
, vol.25
, pp. 745-748
-
-
Nusinzon, I.1
Horvath, C.M.2
-
81
-
-
0037642133
-
Deacetylase activity is required for recruitment of the basal transcription machinery and transactivation by STAT5
-
Rascle A., Johnston J.A., and Amati B. Deacetylase activity is required for recruitment of the basal transcription machinery and transactivation by STAT5. Mol Cell Biol 23 (2003) 4162-4173
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4162-4173
-
-
Rascle, A.1
Johnston, J.A.2
Amati, B.3
-
82
-
-
0034142208
-
A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5
-
Wang D., Moriggl R., Stravopodis D., Carpino N., Marine J.C., Teglund S., et al. A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5. EMBO J 19 (2000) 392-399
-
(2000)
EMBO J
, vol.19
, pp. 392-399
-
-
Wang, D.1
Moriggl, R.2
Stravopodis, D.3
Carpino, N.4
Marine, J.C.5
Teglund, S.6
-
83
-
-
20444476625
-
SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling
-
Tanaka T., Soriano M.A., and Grusby M.J. SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling. Immunity 22 (2005) 729-736
-
(2005)
Immunity
, vol.22
, pp. 729-736
-
-
Tanaka, T.1
Soriano, M.A.2
Grusby, M.J.3
-
84
-
-
4644261307
-
The STAT3 isoforms alpha and beta have unique and specific functions
-
Maritano D., Sugrue M.L., Tininini S., Dewilde S., Strobl B., Fu X., et al. The STAT3 isoforms alpha and beta have unique and specific functions. Nat Immunol 5 (2004) 401-409
-
(2004)
Nat Immunol
, vol.5
, pp. 401-409
-
-
Maritano, D.1
Sugrue, M.L.2
Tininini, S.3
Dewilde, S.4
Strobl, B.5
Fu, X.6
-
85
-
-
0035265830
-
Cooperation between STAT3 and c-jun suppresses Fas transcription
-
Ivanov V.N., Bhoumik A., Krasilnikov M., Raz R., Owen-Schaub L.B., Levy D., et al. Cooperation between STAT3 and c-jun suppresses Fas transcription. Mol Cell 7 (2001) 517-528
-
(2001)
Mol Cell
, vol.7
, pp. 517-528
-
-
Ivanov, V.N.1
Bhoumik, A.2
Krasilnikov, M.3
Raz, R.4
Owen-Schaub, L.B.5
Levy, D.6
-
86
-
-
0030024563
-
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
-
Durbin J.E., Hackenmiller R., Simon M.C., and Levy D.E. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84 (1996) 443-450
-
(1996)
Cell
, vol.84
, pp. 443-450
-
-
Durbin, J.E.1
Hackenmiller, R.2
Simon, M.C.3
Levy, D.E.4
-
87
-
-
13344282731
-
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
-
Meraz M.A., White J.M., Sheehan K.C., Bach E.A., Rodig S.J., Dighe A.S., et al. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84 (1996) 431-442
-
(1996)
Cell
, vol.84
, pp. 431-442
-
-
Meraz, M.A.1
White, J.M.2
Sheehan, K.C.3
Bach, E.A.4
Rodig, S.J.5
Dighe, A.S.6
-
88
-
-
34547123145
-
Novel STAT1 alleles in otherwise healthy patients with mycobacterial disease
-
Chapgier A., Boisson-Dupuis S., Jouanguy E., Vogt G., Feinberg J., Prochnicka-Chalufour A., et al. Novel STAT1 alleles in otherwise healthy patients with mycobacterial disease. PLoS Genet 2 (2006) e131
-
(2006)
PLoS Genet
, vol.2
-
-
Chapgier, A.1
Boisson-Dupuis, S.2
Jouanguy, E.3
Vogt, G.4
Feinberg, J.5
Prochnicka-Chalufour, A.6
-
89
-
-
0032948177
-
A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection
-
Jouanguy E., Lamhamedi-Cherradi S., Lammas D., Dorman S.E., Fondaneche M.C., Dupuis S., et al. A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection. Nat Genet 21 (1999) 370-378
-
(1999)
Nat Genet
, vol.21
, pp. 370-378
-
-
Jouanguy, E.1
Lamhamedi-Cherradi, S.2
Lammas, D.3
Dorman, S.E.4
Fondaneche, M.C.5
Dupuis, S.6
-
90
-
-
0037062503
-
Mutational switch of an IL-6 response to an interferon-gamma -like response
-
Costa-Pereira A.P., Tininini S., Strobl B., Alonzi T., Schlaak J.F., Is'harc H., et al. Mutational switch of an IL-6 response to an interferon-gamma -like response. Proc Natl Acad Sci USA 99 (2002) 8043-8047
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8043-8047
-
-
Costa-Pereira, A.P.1
Tininini, S.2
Strobl, B.3
Alonzi, T.4
Schlaak, J.F.5
Is'harc, H.6
-
91
-
-
0027434082
-
Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways
-
Muller M., Laxton C., Briscoe J., Schindler C., Improta T., Darnell Jr. J.E., et al. Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways. EMBO J 12 (1993) 4221-4228
-
(1993)
EMBO J
, vol.12
, pp. 4221-4228
-
-
Muller, M.1
Laxton, C.2
Briscoe, J.3
Schindler, C.4
Improta, T.5
Darnell Jr., J.E.6
-
92
-
-
0028242693
-
Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein
-
Improta T., Schindler C., Horvath C.M., Kerr I.M., Stark G.R., and Darnell Jr. J.E. Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein. Proc Natl Acad Sci USA 91 (1994) 4776-4780
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4776-4780
-
-
Improta, T.1
Schindler, C.2
Horvath, C.M.3
Kerr, I.M.4
Stark, G.R.5
Darnell Jr., J.E.6
-
93
-
-
0029655971
-
Function of Stat2 protein in transcriptional activation by alpha interferon
-
Qureshi S.A., Leung S., Kerr I.M., Stark G.R., and Darnell Jr. J.E. Function of Stat2 protein in transcriptional activation by alpha interferon. Mol Cell Biol 16 (1996) 288-293
-
(1996)
Mol Cell Biol
, vol.16
, pp. 288-293
-
-
Qureshi, S.A.1
Leung, S.2
Kerr, I.M.3
Stark, G.R.4
Darnell Jr., J.E.5
-
94
-
-
35349009932
-
Interferon modulation of cellular microRNAs as an antiviral mechanism
-
Pedersen I.M., Cheng G., Wieland S., Volinia S., Croce C.M., Chisari F.V., et al. Interferon modulation of cellular microRNAs as an antiviral mechanism. Nature 449 (2007) 919-922
-
(2007)
Nature
, vol.449
, pp. 919-922
-
-
Pedersen, I.M.1
Cheng, G.2
Wieland, S.3
Volinia, S.4
Croce, C.M.5
Chisari, F.V.6
-
95
-
-
0034515268
-
Immune response in Stat2 knockout mice
-
Park C., Li S., Cha E., and Schindler C. Immune response in Stat2 knockout mice. Immunity 13 (2000) 795-804
-
(2000)
Immunity
, vol.13
, pp. 795-804
-
-
Park, C.1
Li, S.2
Cha, E.3
Schindler, C.4
-
96
-
-
13844296660
-
Viruses evade the immune system through type I interferon-mediated STAT2-dependent, but STAT1-independent, signaling
-
Hahm B., Trifilo M.J., Zuniga E.I., and Oldstone M.B. Viruses evade the immune system through type I interferon-mediated STAT2-dependent, but STAT1-independent, signaling. Immunity 22 (2005) 247-257
-
(2005)
Immunity
, vol.22
, pp. 247-257
-
-
Hahm, B.1
Trifilo, M.J.2
Zuniga, E.I.3
Oldstone, M.B.4
-
97
-
-
34250856229
-
Stat2-dependent regulation of MHC class II expression
-
Zhao W., Cha E.N., Lee C., Park C.Y., and Schindler C. Stat2-dependent regulation of MHC class II expression. J Immunol 179 (2007) 463-471
-
(2007)
J Immunol
, vol.179
, pp. 463-471
-
-
Zhao, W.1
Cha, E.N.2
Lee, C.3
Park, C.Y.4
Schindler, C.5
-
98
-
-
0028303977
-
Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
-
Akira S., Nishio Y., Inoue M., Wang X.-J., Wei S., Matsusaka T., et al. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 77 (1994) 63-71
-
(1994)
Cell
, vol.77
, pp. 63-71
-
-
Akira, S.1
Nishio, Y.2
Inoue, M.3
Wang, X.-J.4
Wei, S.5
Matsusaka, T.6
-
99
-
-
0032845125
-
Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation
-
Zhang X., Wrzeszczynska M.H., Horvath C.M., and Darnell Jr. J.E. Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation. Mol Cell Biol 19 (1999) 7138-7146
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7138-7146
-
-
Zhang, X.1
Wrzeszczynska, M.H.2
Horvath, C.M.3
Darnell Jr., J.E.4
-
100
-
-
36248941490
-
IL-10 or not IL-10: that is the question
-
Jankovic D., and Trinchieri G. IL-10 or not IL-10: that is the question. Nat Immunol 8 (2007) 1281-1283
-
(2007)
Nat Immunol
, vol.8
, pp. 1281-1283
-
-
Jankovic, D.1
Trinchieri, G.2
-
101
-
-
0030935260
-
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
-
Takeda K., Noguchi K., Shi W., Tanaka T., Matsumoto M., Yoshida N., et al. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc Natl Acad Sci USA 94 (1997) 3801-3804
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3801-3804
-
-
Takeda, K.1
Noguchi, K.2
Shi, W.3
Tanaka, T.4
Matsumoto, M.5
Yoshida, N.6
-
102
-
-
33746397211
-
Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex
-
Yoshimatsu T., Kawaguchi D., Oishi K., Takeda K., Akira S., Masuyama N., et al. Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex. Development 133 (2006) 2553-2563
-
(2006)
Development
, vol.133
, pp. 2553-2563
-
-
Yoshimatsu, T.1
Kawaguchi, D.2
Oishi, K.3
Takeda, K.4
Akira, S.5
Masuyama, N.6
-
103
-
-
85047690540
-
Stat-3 is required for pulmonary homeostasis during hyperoxia
-
Hokuto I., Ikegami M., Yoshida M., Takeda K., Akira S., Perl A.K., et al. Stat-3 is required for pulmonary homeostasis during hyperoxia. J Clin Invest 113 (2004) 28-37
-
(2004)
J Clin Invest
, vol.113
, pp. 28-37
-
-
Hokuto, I.1
Ikegami, M.2
Yoshida, M.3
Takeda, K.4
Akira, S.5
Perl, A.K.6
-
104
-
-
1842584949
-
Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation
-
Gao Q., Wolfgang M.J., Neschen S., Morino K., Horvath T.L., Shulman G.I., et al. Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation. Proc Natl Acad Sci USA 101 (2004) 4661-4666
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4661-4666
-
-
Gao, Q.1
Wolfgang, M.J.2
Neschen, S.3
Morino, K.4
Horvath, T.L.5
Shulman, G.I.6
-
105
-
-
0035131190
-
Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver
-
Alonzi T., Maritano D., Gorgoni B., Rizzuto G., Libert C., and Poli V. Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver. Mol Cell Biol 21 (2001) 1621-1632
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1621-1632
-
-
Alonzi, T.1
Maritano, D.2
Gorgoni, B.3
Rizzuto, G.4
Libert, C.5
Poli, V.6
-
106
-
-
0036256644
-
What does Stat3 do?
-
Levy D.E., and Lee C.K. What does Stat3 do?. J Clin Invest 109 (2002) 1143-1148
-
(2002)
J Clin Invest
, vol.109
, pp. 1143-1148
-
-
Levy, D.E.1
Lee, C.K.2
-
107
-
-
0036338213
-
STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation
-
Lee C.K., Raz R., Gimeno R., Gertner R., Wistinghausen B., Takeshita K., et al. STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation. Immunity 17 (2002) 63-72
-
(2002)
Immunity
, vol.17
, pp. 63-72
-
-
Lee, C.K.1
Raz, R.2
Gimeno, R.3
Gertner, R.4
Wistinghausen, B.5
Takeshita, K.6
-
108
-
-
0033214903
-
Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3
-
Chapman R.S., Lourenco P.C., Tonner E., Flint D.J., Selbert S., Takeda K., et al. Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3. Genes Dev 13 (1999) 2604-2616
-
(1999)
Genes Dev
, vol.13
, pp. 2604-2616
-
-
Chapman, R.S.1
Lourenco, P.C.2
Tonner, E.3
Flint, D.J.4
Selbert, S.5
Takeda, K.6
-
109
-
-
35348961447
-
STAT3 signaling and the hyper-IgE syndrome
-
Levy D.E., and Loomis C.A. STAT3 signaling and the hyper-IgE syndrome. N Engl J Med 357 (2007) 1655-1658
-
(2007)
N Engl J Med
, vol.357
, pp. 1655-1658
-
-
Levy, D.E.1
Loomis, C.A.2
-
110
-
-
39449093328
-
Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway
-
de la Iglesia N., Konopka G., Puram S.V., Chan J.A., Bachoo R.M., You M.J., et al. Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev (2008)
-
(2008)
Genes Dev
-
-
de la Iglesia, N.1
Konopka, G.2
Puram, S.V.3
Chan, J.A.4
Bachoo, R.M.5
You, M.J.6
-
111
-
-
25444454543
-
New and old functions of STAT3: a pivotal target for individualized treatment of cancer
-
Inghirami G., Chiarle R., Simmons W.J., Piva R., Schlessinger K., and Levy D.E. New and old functions of STAT3: a pivotal target for individualized treatment of cancer. Cell Cycle 4 (2005) 1131-1133
-
(2005)
Cell Cycle
, vol.4
, pp. 1131-1133
-
-
Inghirami, G.1
Chiarle, R.2
Simmons, W.J.3
Piva, R.4
Schlessinger, K.5
Levy, D.E.6
-
112
-
-
39549091298
-
Signal transduction pathways and transcriptional regulation in the control of Th17 differentiation
-
Chen Z., Laurence A., and O'Shea J.J. Signal transduction pathways and transcriptional regulation in the control of Th17 differentiation. Semin Immunol 19 (2007) 400-408
-
(2007)
Semin Immunol
, vol.19
, pp. 400-408
-
-
Chen, Z.1
Laurence, A.2
O'Shea, J.J.3
-
113
-
-
34247122412
-
Stat3 and Stat4 direct development of IL-17-secreting Th cells
-
Mathur A.N., Chang H.C., Zisoulis D.G., Stritesky G.L., Yu Q., O'Malley J.T., et al. Stat3 and Stat4 direct development of IL-17-secreting Th cells. J Immunol 178 (2007) 4901-4907
-
(2007)
J Immunol
, vol.178
, pp. 4901-4907
-
-
Mathur, A.N.1
Chang, H.C.2
Zisoulis, D.G.3
Stritesky, G.L.4
Yu, Q.5
O'Malley, J.T.6
-
114
-
-
49149127436
-
STAT3 is indispensable to IL-27-mediated cell proliferation but not to IL-27-induced Th1 differentiation and suppression of proinflammatory cytokine production
-
Owaki T., Asakawa M., Morishima N., Mizoguchi I., Fukai F., Takeda K., et al. STAT3 is indispensable to IL-27-mediated cell proliferation but not to IL-27-induced Th1 differentiation and suppression of proinflammatory cytokine production. J Immunol 180 (2008) 2903-2911
-
(2008)
J Immunol
, vol.180
, pp. 2903-2911
-
-
Owaki, T.1
Asakawa, M.2
Morishima, N.3
Mizoguchi, I.4
Fukai, F.5
Takeda, K.6
-
115
-
-
33845865825
-
Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment
-
Yu H., Kortylewski M., and Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol 7 (2007) 41-51
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 41-51
-
-
Yu, H.1
Kortylewski, M.2
Pardoll, D.3
-
116
-
-
0033529704
-
Stat3 as an oncogene
-
Bromberg J.F., Wrzeszczynska M.H., Devgan G., Zhao Y., Pestell R.G.C., and Albanese Darnell J.E. Stat3 as an oncogene. Cell 98 (1999) 295-303
-
(1999)
Cell
, vol.98
, pp. 295-303
-
-
Bromberg, J.F.1
Wrzeszczynska, M.H.2
Devgan, G.3
Zhao, Y.4
Pestell, R.G.C.5
Albanese Darnell, J.E.6
-
117
-
-
40649109728
-
The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer
-
Naugler W.E., and Karin M. The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer. Trends Mol Med 14 (2008) 109-119
-
(2008)
Trends Mol Med
, vol.14
, pp. 109-119
-
-
Naugler, W.E.1
Karin, M.2
-
118
-
-
0029157421
-
Distribution of the mammalian Stat gene family in mouse chromosomes
-
Copeland N.G., Gilbert D.J., Schindler C., Zhong Z., Wen Z., Darnell Jr. J.E., et al. Distribution of the mammalian Stat gene family in mouse chromosomes. Genomics 29 (1995) 225-228
-
(1995)
Genomics
, vol.29
, pp. 225-228
-
-
Copeland, N.G.1
Gilbert, D.J.2
Schindler, C.3
Zhong, Z.4
Wen, Z.5
Darnell Jr., J.E.6
-
119
-
-
21844444831
-
New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
-
Hunter C.A. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat Rev Immunol 5 (2005) 521-531
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 521-531
-
-
Hunter, C.A.1
-
120
-
-
0028349735
-
Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
-
Zhong Z., Wen Z., and Darnell Jr. J.E. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 264 (1994) 95-98
-
(1994)
Science
, vol.264
, pp. 95-98
-
-
Zhong, Z.1
Wen, Z.2
Darnell Jr., J.E.3
-
122
-
-
15844396183
-
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
-
Thierfelder W.E., van Deursen J.M., Yamamoto K., Tripp R.A., Sarawar S.R., Carson R.T., et al. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 382 (1996) 171-174
-
(1996)
Nature
, vol.382
, pp. 171-174
-
-
Thierfelder, W.E.1
van Deursen, J.M.2
Yamamoto, K.3
Tripp, R.A.4
Sarawar, S.R.5
Carson, R.T.6
-
123
-
-
0029937270
-
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
-
Kaplan M.H., Sun Y.L., Hoey T., and Grusby M.J. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 382 (1996) 174-177
-
(1996)
Nature
, vol.382
, pp. 174-177
-
-
Kaplan, M.H.1
Sun, Y.L.2
Hoey, T.3
Grusby, M.J.4
-
124
-
-
0037125988
-
STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation
-
Morinobu A., Gadina M., Strober W., Visconti R., Fornace A., Montagna C., et al. STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation. Proc Natl Acad Sci USA 99 (2002) 12281-12286
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12281-12286
-
-
Morinobu, A.1
Gadina, M.2
Strober, W.3
Visconti, R.4
Fornace, A.5
Montagna, C.6
-
125
-
-
0000943469
-
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
-
Teglund S., McKay C., Schuetz E., van Deursen J.M., Stravopodis D., Wang D., et al. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell 93 (1998) 841-850
-
(1998)
Cell
, vol.93
, pp. 841-850
-
-
Teglund, S.1
McKay, C.2
Schuetz, E.3
van Deursen, J.M.4
Stravopodis, D.5
Wang, D.6
-
126
-
-
0030833570
-
Requirement of Stat5b for sexual dimorphism of body growth rates and liver gene expression
-
Udy G.B., Towers R.P., Snell R.G., Wilkins R.J., Park S.H., Ram P.A., et al. Requirement of Stat5b for sexual dimorphism of body growth rates and liver gene expression. Proc Natl Acad Sci USA 94 (1997) 7239-7244
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7239-7244
-
-
Udy, G.B.1
Towers, R.P.2
Snell, R.G.3
Wilkins, R.J.4
Park, S.H.5
Ram, P.A.6
-
127
-
-
4444268818
-
Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation
-
Cui Y., Riedlinger G., Miyoshi K., Tang W., Li C., Deng C.X., et al. Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation. Mol Cell Biol 24 (2004) 8037-8047
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8037-8047
-
-
Cui, Y.1
Riedlinger, G.2
Miyoshi, K.3
Tang, W.4
Li, C.5
Deng, C.X.6
-
128
-
-
32244444750
-
Stat5a/b are essential for normal lymphoid development and differentiation
-
Yao Z., Cui Y., Watford W.T., Bream J.H., Yamaoka K., Hissong B.D., et al. Stat5a/b are essential for normal lymphoid development and differentiation. Proc Natl Acad Sci USA 103 (2006) 1000-1005
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1000-1005
-
-
Yao, Z.1
Cui, Y.2
Watford, W.T.3
Bream, J.H.4
Yamaoka, K.5
Hissong, B.D.6
-
129
-
-
33744546660
-
Signaling mechanisms, interaction partners, and target genes of STAT6
-
Hebenstreit D., Wirnsberger G., Horejs-Hoeck J., and Duschl A. Signaling mechanisms, interaction partners, and target genes of STAT6. Cytokine Growth Factor Rev 17 (2006) 173-188
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 173-188
-
-
Hebenstreit, D.1
Wirnsberger, G.2
Horejs-Hoeck, J.3
Duschl, A.4
-
130
-
-
15844404509
-
Essential role of Stat6 in IL-4 signalling
-
Takeda K., Tanaka T., Shi W., Matsumoto M., Minami M., Kashiwamura S., et al. Essential role of Stat6 in IL-4 signalling. Nature 380 (1996) 627-630
-
(1996)
Nature
, vol.380
, pp. 627-630
-
-
Takeda, K.1
Tanaka, T.2
Shi, W.3
Matsumoto, M.4
Minami, M.5
Kashiwamura, S.6
-
131
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
Shimoda K., van Deursen J., Sangster M.Y., Sarawar S.R., Carson R.T., Tripp R.A., et al. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 380 (1996) 630-633
-
(1996)
Nature
, vol.380
, pp. 630-633
-
-
Shimoda, K.1
van Deursen, J.2
Sangster, M.Y.3
Sarawar, S.R.4
Carson, R.T.5
Tripp, R.A.6
-
132
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
-
Kaplan M.H., Schindler U., Smiley S.T., and Grusby M.J. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4 (1996) 313-319
-
(1996)
Immunity
, vol.4
, pp. 313-319
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
133
-
-
0034657917
-
Modulation of STAT signaling by STAT-interacting proteins
-
Shuai K. Modulation of STAT signaling by STAT-interacting proteins. Oncogene 19 (2000) 2638-2644
-
(2000)
Oncogene
, vol.19
, pp. 2638-2644
-
-
Shuai, K.1
-
134
-
-
0033534562
-
Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling
-
Zhu M., John S., Berg M., and Leonard W.J. Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling. Cell 96 (1999) 121-130
-
(1999)
Cell
, vol.96
, pp. 121-130
-
-
Zhu, M.1
John, S.2
Berg, M.3
Leonard, W.J.4
-
135
-
-
32644449048
-
Acetylation of Stat1 modulates NF-kappaB activity
-
Kramer O.H., Baus D., Knauer S.K., Stein S., Jager E., Stauber R.H., et al. Acetylation of Stat1 modulates NF-kappaB activity. Genes Dev 20 (2006) 473-485
-
(2006)
Genes Dev
, vol.20
, pp. 473-485
-
-
Kramer, O.H.1
Baus, D.2
Knauer, S.K.3
Stein, S.4
Jager, E.5
Stauber, R.H.6
-
136
-
-
33646591224
-
Stat3 activation of NF-{kappa}B p100 processing involves CBP/p300-mediated acetylation
-
Nadiminty N., Lou W., Lee S.O., Lin X., Trump D.L., and Gao A.C. Stat3 activation of NF-{kappa}B p100 processing involves CBP/p300-mediated acetylation. Proc Natl Acad Sci USA 103 (2006) 7264-7269
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7264-7269
-
-
Nadiminty, N.1
Lou, W.2
Lee, S.O.3
Lin, X.4
Trump, D.L.5
Gao, A.C.6
-
137
-
-
12244251445
-
Stat3 dimerization regulated by reversible acetylation of a single lysine residue
-
Yuan Z.L., Guan Y.J., Chatterjee D., and Chin Y.E. Stat3 dimerization regulated by reversible acetylation of a single lysine residue. Science 307 (2005) 269-273
-
(2005)
Science
, vol.307
, pp. 269-273
-
-
Yuan, Z.L.1
Guan, Y.J.2
Chatterjee, D.3
Chin, Y.E.4
-
138
-
-
0942287200
-
The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5
-
Gewinner C., Hart G., Zachara N., Cole R., Beisenherz-Huss C., and Groner B. The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5. J Biol Chem 279 (2004) 3563-3572
-
(2004)
J Biol Chem
, vol.279
, pp. 3563-3572
-
-
Gewinner, C.1
Hart, G.2
Zachara, N.3
Cole, R.4
Beisenherz-Huss, C.5
Groner, B.6
-
139
-
-
33751195939
-
Stat1 and SUMO modification
-
Song L., Bhattacharya S., Yunus A.A., Lima C.D., and Schindler C. Stat1 and SUMO modification. Blood 108 (2006) 3237-3244
-
(2006)
Blood
, vol.108
, pp. 3237-3244
-
-
Song, L.1
Bhattacharya, S.2
Yunus, A.A.3
Lima, C.D.4
Schindler, C.5
-
140
-
-
20644451194
-
Are STATS arginine-methylated?
-
Komyod W., Bauer U.M., Heinrich P.C., Haan S., and Behrmann I. Are STATS arginine-methylated?. J Biol Chem 280 (2005) 21700-21705
-
(2005)
J Biol Chem
, vol.280
, pp. 21700-21705
-
-
Komyod, W.1
Bauer, U.M.2
Heinrich, P.C.3
Haan, S.4
Behrmann, I.5
-
141
-
-
8844266055
-
Arginine methylation of STAT1: a reassessment
-
119; 587-9; discussion 589-90
-
Meissner T., Krause E., Lodige I., and Vinkemeier U. Arginine methylation of STAT1: a reassessment. Cell (2004) 119; 587-9; discussion 589-90
-
(2004)
Cell
-
-
Meissner, T.1
Krause, E.2
Lodige, I.3
Vinkemeier, U.4
-
142
-
-
0346792731
-
Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity
-
Varinou L., Ramsauer K., Karaghiosoff M., Kolbe T., Pfeffer K., Muller M., et al. Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity. Immunity 19 (2003) 793-802
-
(2003)
Immunity
, vol.19
, pp. 793-802
-
-
Varinou, L.1
Ramsauer, K.2
Karaghiosoff, M.3
Kolbe, T.4
Pfeffer, K.5
Muller, M.6
-
143
-
-
0347624595
-
Essential role of STAT3 in postnatal survival and growth revealed by mice lacking STAT3 serine 727 phosphorylation
-
Shen Y., Schlessinger K., Zhu X., Meffre E., Quimby F., Levy D.E., et al. Essential role of STAT3 in postnatal survival and growth revealed by mice lacking STAT3 serine 727 phosphorylation. Mol Cell Biol 24 (2004) 407-419
-
(2004)
Mol Cell Biol
, vol.24
, pp. 407-419
-
-
Shen, Y.1
Schlessinger, K.2
Zhu, X.3
Meffre, E.4
Quimby, F.5
Levy, D.E.6
-
144
-
-
20144376594
-
STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation
-
Kojima H., Sasaki T., Ishitani T., Iemura S., Zhao H., Kaneko S., et al. STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation. Proc Natl Acad Sci USA 102 (2005) 4524-4529
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4524-4529
-
-
Kojima, H.1
Sasaki, T.2
Ishitani, T.3
Iemura, S.4
Zhao, H.5
Kaneko, S.6
-
145
-
-
33847687659
-
Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity
-
Tenoever B.R., Ng S.L., Chua M.A., McWhirter S.M., Garcia-Sastre A., and Maniatis T. Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity. Science 315 (2007) 1274-1278
-
(2007)
Science
, vol.315
, pp. 1274-1278
-
-
Tenoever, B.R.1
Ng, S.L.2
Chua, M.A.3
McWhirter, S.M.4
Garcia-Sastre, A.5
Maniatis, T.6
-
146
-
-
11244277091
-
Protein tyrosine phosphatases and the immune response
-
Mustelin T., Vang T., and Bottini N. Protein tyrosine phosphatases and the immune response. Nat Rev Immunol 5 (2005) 43-57
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 43-57
-
-
Mustelin, T.1
Vang, T.2
Bottini, N.3
-
147
-
-
33847290896
-
Regulation of signal transducer and activator of transcription signaling by the tyrosine phosphatase PTP-BL
-
Nakahira M., Tanaka T., Robson B.E., Mizgerd J.P., and Grusby M.J. Regulation of signal transducer and activator of transcription signaling by the tyrosine phosphatase PTP-BL. Immunity 26 (2007) 163-176
-
(2007)
Immunity
, vol.26
, pp. 163-176
-
-
Nakahira, M.1
Tanaka, T.2
Robson, B.E.3
Mizgerd, J.P.4
Grusby, M.J.5
-
148
-
-
0035905767
-
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
-
Irie-Sasaki J., Sasaki T., Matsumoto W., Opavsky A., Cheng M., Welstead G., et al. CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling. Nature 409 (2001) 349-354
-
(2001)
Nature
, vol.409
, pp. 349-354
-
-
Irie-Sasaki, J.1
Sasaki, T.2
Matsumoto, W.3
Opavsky, A.4
Cheng, M.5
Welstead, G.6
-
149
-
-
0032545279
-
Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction
-
Haque S.J., Harbor P., Tabrizi M., Yi T., and Williams B.R. Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction. J Biol Chem 273 (1998) 33893-33896
-
(1998)
J Biol Chem
, vol.273
, pp. 33893-33896
-
-
Haque, S.J.1
Harbor, P.2
Tabrizi, M.3
Yi, T.4
Williams, B.R.5
-
150
-
-
0034671546
-
A cytosolic protein tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b
-
Aoki N., and Matsuda T. A cytosolic protein tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b. J Biol Chem (2000)
-
(2000)
J Biol Chem
-
-
Aoki, N.1
Matsuda, T.2
-
151
-
-
0028956353
-
Specefic recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of Jak2 and termination of proliferative signals
-
Klingmueller U., Lorenz U., Cantley L.C., Neel B.G., and Lodish H.F. Specefic recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of Jak2 and termination of proliferative signals. Cell 80 (1995) 729-738
-
(1995)
Cell
, vol.80
, pp. 729-738
-
-
Klingmueller, U.1
Lorenz, U.2
Cantley, L.C.3
Neel, B.G.4
Lodish, H.F.5
-
152
-
-
7244255836
-
Getting the message across, STAT! Design principles of a molecular signaling circuit
-
Vinkemeier U. Getting the message across, STAT! Design principles of a molecular signaling circuit. J Cell Biol 167 (2004) 197-201
-
(2004)
J Cell Biol
, vol.167
, pp. 197-201
-
-
Vinkemeier, U.1
-
153
-
-
0036318564
-
Identification of a nuclear Stat1 protein tyrosine phosphatase
-
ten Hoeve J., de Jesus Ibarra-Sanchez M., Fu Y., Zhu W., Tremblay M., David M., et al. Identification of a nuclear Stat1 protein tyrosine phosphatase. Mol Cell Biol 22 (2002) 5662-5668
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5662-5668
-
-
ten Hoeve, J.1
de Jesus Ibarra-Sanchez, M.2
Fu, Y.3
Zhu, W.4
Tremblay, M.5
David, M.6
-
154
-
-
52949090018
-
SOCS regulation of the JAK/STAT signalling pathway
-
Croker B.A., Kiu H., and Nicholson S.E. SOCS regulation of the JAK/STAT signalling pathway. Semin Cell Dev Biol 19 (2008) 414-422
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 414-422
-
-
Croker, B.A.1
Kiu, H.2
Nicholson, S.E.3
-
155
-
-
52949087943
-
Identification of JAK/STAT pathway regulators-insights from RNAi screens
-
Müller P., Boutros M., and Zeidler M.P. Identification of JAK/STAT pathway regulators-insights from RNAi screens. Semin Cell Dev Biol 19 (2008) 360-369
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 360-369
-
-
Müller, P.1
Boutros, M.2
Zeidler, M.P.3
-
156
-
-
52949096859
-
The function of Stat3 in tumor cells and their microenvironment
-
Groner B., Lucks P., and Borghouts C. The function of Stat3 in tumor cells and their microenvironment. Semin Cell Dev Biol 19 (2008) 341-350
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 341-350
-
-
Groner, B.1
Lucks, P.2
Borghouts, C.3
-
157
-
-
52949127317
-
The JAK kinases: not just another kinase drug discovery target
-
Wilks A.F. The JAK kinases: not just another kinase drug discovery target. Semin Cell Dev Biol 19 (2008) 319-328
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 319-328
-
-
Wilks, A.F.1
-
158
-
-
52949089050
-
JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies
-
Vainchenker W., Dusa A., and Constantinescu S.N. JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies. Semin Cell Dev Biol 19 (2008) 385-393
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 385-393
-
-
Vainchenker, W.1
Dusa, A.2
Constantinescu, S.N.3
|