-
1
-
-
0026035169
-
Differential response of the human 6-16 and 9-27 genes to α and γ interferons
-
Ackrill, A. M., L. E. Reid, C. S. Gilbert, D. R. Gewert, A. C. G. Porter, A. R. Lewin, G. R. Stark, and I. M. Kerr. 1991. Differential response of the human 6-16 and 9-27 genes to α and γ interferons. Nucleic Acids Res 19:591-598.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 591-598
-
-
Ackrill, A.M.1
Reid, L.E.2
Gilbert, C.S.3
Gewert, D.R.4
Porter, A.C.G.5
Lewin, A.R.6
Stark, G.R.7
Kerr, I.M.8
-
2
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell, J. E., Jr., I. M. Kerr, and G. M. Stark. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins Science 264:1415-1421.
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell Jr., J.E.1
Kerr, I.M.2
Stark, G.M.3
-
3
-
-
0021707311
-
Transcriptional and post-transcriptional regulation of interferon-induced gene expression in human cells
-
Friedman, R. L., S. P. Manly, M. McMahon, I. M. Kerr, and G. R. Stark. 1984. Transcriptional and post-transcriptional regulation of interferon-induced gene expression in human cells. Cell 38:745-755
-
(1984)
Cell
, vol.38
, pp. 745-755
-
-
Friedman, R.L.1
Manly, S.P.2
McMahon, M.3
Kerr, I.M.4
Stark, G.R.5
-
4
-
-
0025172081
-
ISGF3. The transcriptional activator induced by interferon α, consists of multiple interacting polypeptide chains
-
Fu, X.-Y., D. S. Kessler, S. A. Veals, D. E. Levy, and J. E. Darnell, Jr. 1990. ISGF3. the transcriptional activator induced by interferon α, consists of multiple interacting polypeptide chains Proc. Natl Acad. Sci. USA 87:8555-8559.
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 8555-8559
-
-
Fu, X.-Y.1
Kessler, D.S.2
Veals, S.A.3
Levy, D.E.4
Darnell Jr., J.E.5
-
5
-
-
0026686488
-
The proteins of ISGF-3: The interteron α-induced transcriptional activator defines a gene family involved in signal transduction
-
Fu, X.-Y., C. Schindler, T. Improta, R. Aebersold, and J. E. Darnell. Jr. 1992. The proteins of ISGF-3: the interteron α-induced transcriptional activator defines a gene family involved in signal transduction. Proc. Natl. Acad. Sci. USA 89:7840-7843.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7840-7843
-
-
Fu, X.-Y.1
Schindler, C.2
Improta, T.3
Aebersold, R.4
Darnell Jr., J.E.5
-
6
-
-
0028175454
-
Ligand-induced IFN-γ receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91)
-
Greenlund, A. L., M. A. Farrar, B. L. Viviano, and R. D. Schreiber. 1994 Ligand-induced IFN-γ receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91). EMBO J 13:1591-1600.
-
(1994)
EMBO J
, vol.13
, pp. 1591-1600
-
-
Greenlund, A.L.1
Farrar, M.A.2
Viviano, B.L.3
Schreiber, R.D.4
-
7
-
-
0028946158
-
STAT SH2 groups contribute to specific interferon signalling by the Jak-STAT pathway
-
Heim, M. H., I. M. Kerr, G. R. Stark, and J. E. Darnell, Jr. 1995. STAT SH2 groups contribute to specific interferon signalling by the Jak-STAT pathway. Science 267:1347-1349.
-
(1995)
Science
, vol.267
, pp. 1347-1349
-
-
Heim, M.H.1
Kerr, I.M.2
Stark, G.R.3
Darnell Jr., J.E.4
-
8
-
-
0023239517
-
Functional inactivation of genes by dominant negative mutations
-
Herskowitz, I. 1987. Functional inactivation of genes by dominant negative mutations Nature (London) 329:219-222.
-
(1987)
Nature (London)
, vol.329
, pp. 219-222
-
-
Herskowitz, I.1
-
9
-
-
0028913109
-
A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
-
Horvath, C. M., Z. Wen, and J. E. Darnell, Jr. 1995. A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes Dev. 9:984-994.
-
(1995)
Genes Dev.
, vol.9
, pp. 984-994
-
-
Horvath, C.M.1
Wen, Z.2
Darnell Jr., J.E.3
-
10
-
-
0028242693
-
ISGF-3 formation requires phosphorylated Stat91 but Stat113 is phosphorylated independently of Stat91
-
Improta, T., C. Schindler, C. M. Horvath, I. M. Kerr, G. R. Stark, and J. E. Darnell, Jr. 1994. ISGF-3 formation requires phosphorylated Stat91 but Stat113 is phosphorylated independently of Stat91. Proc Natl. Acad. Sci. USA 91:4776-4780
-
(1994)
Proc Natl. Acad. Sci. USA
, vol.91
, pp. 4776-4780
-
-
Improta, T.1
Schindler, C.2
Horvath, C.M.3
Kerr, I.M.4
Stark, G.R.5
Darnell Jr., J.E.6
-
11
-
-
0027165321
-
Induction of the Ly-6A/E gene by both interferon α/β and γ requires a DNA element to which a tyrosine phosphorylated 91 kDa protein binds
-
Khan, K. D., K. Shuai, G. Lindwall, S. E. Maher, J. E. Darnell, Jr., and A. L. M. Bothwell. 1993. Induction of the Ly-6A/E gene by both interferon α/β and γ requires a DNA element to which a tyrosine phosphorylated 91 kDa protein binds. Proc. Natl. Acad. Sci. USA 90:6805-6810.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6805-6810
-
-
Khan, K.D.1
Shuai, K.2
Lindwall, G.3
Maher, S.E.4
Darnell Jr., J.E.5
Bothwell, A.L.M.6
-
12
-
-
0021682746
-
Transcriptional induction of two genes in human cells by β interferon
-
Larner, A. C., G. Jonak, Y.-S. Cheng, B. Korant, E. Knight, Jr., and J. E. Darnell. Jr. 1984 Transcriptional induction of two genes in human cells by β interferon. Proc. Natl. Acad. Sci. USA 81:6733-6737
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 6733-6737
-
-
Larner, A.C.1
Jonak, G.2
Cheng, Y.-S.3
Korant, B.4
Knight Jr., E.5
Darnell Jr., J.E.6
-
13
-
-
0028798823
-
Role of STAT2 in the alpha interferon signaling pathway
-
Leung, S., S. A. Qureshi, I. M. Kerr, J. E. Darnell, Jr., and G. R. Stark. 1995. Role of STAT2 in the alpha interferon signaling pathway. Mol. Cell. Biol 15:1312-1317.
-
(1995)
Mol. Cell. Biol
, vol.15
, pp. 1312-1317
-
-
Leung, S.1
Qureshi, S.A.2
Kerr, I.M.3
Darnell Jr., J.E.4
Stark, G.R.5
-
14
-
-
0024721567
-
Cytoplasmic activation of ISGF3, the positive regulator of interferon-α stimulated transcription, reconstituted in vitro
-
Levy, D. E., D. S. Kessler, R. I. Pine, and J. E. Darnell, Jr. 1989. Cytoplasmic activation of ISGF3, the positive regulator of interferon-α stimulated transcription, reconstituted in vitro Genes Dev 3:1362-1372.
-
(1989)
Genes Dev
, vol.3
, pp. 1362-1372
-
-
Levy, D.E.1
Kessler, D.S.2
Pine, R.I.3
Darnell Jr., J.E.4
-
15
-
-
0023987751
-
Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative control
-
Levy, D. E., D. S. Kessler, R. Pine, N. Reich, and J. E. Darnell, Jr. 1988. Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative control. Genes Dev. 2:383-393.
-
(1988)
Genes Dev.
, vol.2
, pp. 383-393
-
-
Levy, D.E.1
Kessler, D.S.2
Pine, R.3
Reich, N.4
Darnell Jr., J.E.5
-
17
-
-
0027434082
-
Complementation of a mutant cell line: Central role of the 91-kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathway
-
Muller, M., C. Laxton, J. Briscoe, C. Schindler, T. Improta, J. E. Darnell, Jr., G. R. Stark, and I. M. Kerr. 1993. Complementation of a mutant cell line: central role of the 91-kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathway. EMBO J 12:4221-4228.
-
(1993)
EMBO J
, vol.12
, pp. 4221-4228
-
-
Muller, M.1
Laxton, C.2
Briscoe, J.3
Schindler, C.4
Improta, T.5
Darnell Jr., J.E.6
Stark, G.R.7
Kerr, I.M.8
-
18
-
-
0024404483
-
Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway
-
Pellegrini, S., J. John, M. Shearer, I. M. Kerr, and G. R. Stark. 1989. Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway. Mol Cell. Biol. 9:4605-4612.
-
(1989)
Mol Cell. Biol.
, vol.9
, pp. 4605-4612
-
-
Pellegrini, S.1
John, J.2
Shearer, M.3
Kerr, I.M.4
Stark, G.R.5
-
19
-
-
0025880813
-
An inhibitory mutant of c-Raf-1 blocks v-Src-induced activation of the Egr-1 promoter
-
Qureshi, S. A., M. Rim, J. Bruder, W. Kolch, U. Rapp, V. P. Sukhatme, and D. A. Foster. 1991. An inhibitory mutant of c-Raf-1 blocks v-Src-induced activation of the Egr-1 promoter. J. Biol. Chem. 266:20594-20597.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 20594-20597
-
-
Qureshi, S.A.1
Rim, M.2
Bruder, J.3
Kolch, W.4
Rapp, U.5
Sukhatme, V.P.6
Foster, D.A.7
-
20
-
-
0029061508
-
Tyrosine phosphorylated Stal1 and Stat2 plus a 48 kD protein all contact DNA in forming the interferon stimulated gene factor 3 (ISGF3)
-
Qureshi, S. A., M. Salditt-Georgieff, and J. E. Darnell, Jr. 1995. Tyrosine phosphorylated Stal1 and Stat2 plus a 48 kD protein all contact DNA in forming the interferon stimulated gene factor 3 (ISGF3). Proc. Natl. Acad. Sci. USA 92:3929-3933
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3929-3933
-
-
Qureshi, S.A.1
Salditt-Georgieff, M.2
Darnell Jr., J.E.3
-
21
-
-
0342535752
-
Interferon-induced transcription of a gene encoding a 15 kDa protein depends on an upstream enhancer element
-
Reich, N., B. Evans, D. E. Levy, D. Fahey, E. Knight, Jr., and J. E. Darnell. Jr. 1987 Interferon-induced transcription of a gene encoding a 15 kDa protein depends on an upstream enhancer element. Proc. Natl. Acad Sci USA 84:6394-6398.
-
(1987)
Proc. Natl. Acad Sci USA
, vol.84
, pp. 6394-6398
-
-
Reich, N.1
Evans, B.2
Levy, D.E.3
Fahey, D.4
Knight Jr., E.5
Darnell Jr., J.E.6
-
22
-
-
0023883901
-
Transcription of interferon-stimulated genes is induced by adenovirus particles but is suppressed by E1A transcription
-
Reich, N., R. Pine, L. Levy, and J. E. Darnell, Jr. 1988. Transcription of interferon-stimulated genes is induced by adenovirus particles but is suppressed by E1A transcription J. Virol. 62:114-119.
-
(1988)
J. Virol.
, vol.62
, pp. 114-119
-
-
Reich, N.1
Pine, R.2
Levy, L.3
Darnell Jr., J.E.4
-
23
-
-
0003903343
-
-
Cold Spring Harbor laboratory, Cold Spring Harbor, N.Y.
-
Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989 Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor laboratory, Cold Spring Harbor, N.Y.
-
(1989)
Molecular Cloning: A Laboratory Manual, 2nd Ed.
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
24
-
-
0029069145
-
Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
-
Schindler, C., and J. E. Darnell, Jr. 1995. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway Annu Rev Biochem 64:621-651.
-
(1995)
Annu Rev Biochem
, vol.64
, pp. 621-651
-
-
Schindler, C.1
Darnell Jr., J.E.2
-
25
-
-
0026725868
-
Proteins of transcription factor ISGF-3: One gene encodes the 91 and 84 kDa ISGF-3 proteins that are activated by interferon-α
-
Schindler, C., X.-Y. Fu, T. Improta, R. Aebersold, and J. E. Darnell, Jr. 1992. Proteins of transcription factor ISGF-3: one gene encodes the 91 and 84 kDa ISGF-3 proteins that are activated by interferon-α Proc Natl. Acad. Sci. USA 89:7836-7839
-
(1992)
Proc Natl. Acad. Sci. USA
, vol.89
, pp. 7836-7839
-
-
Schindler, C.1
Fu, X.-Y.2
Improta, T.3
Aebersold, R.4
Darnell Jr., J.E.5
-
26
-
-
0026770248
-
Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
-
Schindler, C., K. Shuai, V. R. Prezioso, and J. E. Darnell, Jr. 1992. Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 257:809-815.
-
(1992)
Science
, vol.257
, pp. 809-815
-
-
Schindler, C.1
Shuai, K.2
Prezioso, V.R.3
Darnell Jr., J.E.4
-
27
-
-
0028349904
-
Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
-
Shuai, K., C. M. Horvath, L. H. Tsai-Huang, S. Qureshi, D. Cowburn, and J. E. Darnell, Jr. 1994. Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. Cell 76:821-828.
-
(1994)
Cell
, vol.76
, pp. 821-828
-
-
Shuai, K.1
Horvath, C.M.2
Tsai-Huang, L.H.3
Qureshi, S.4
Cowburn, D.5
Darnell Jr., J.E.6
-
28
-
-
0027090310
-
Activation of transcription by IFN-γ: Tyrosine phosphorylation of a 91 kD DNA binding protein
-
Shuai, K., C. Schindler, V. R. Prezioso, and J. E. Darnell, Jr. 1992. Activation of transcription by IFN-γ: tyrosine phosphorylation of a 91 kD DNA binding protein Science 259:1808-1812
-
(1992)
Science
, vol.259
, pp. 1808-1812
-
-
Shuai, K.1
Schindler, C.2
Prezioso, V.R.3
Darnell Jr., J.E.4
-
29
-
-
0026778338
-
Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins
-
Veals, S. A., C. Schindler, D. Leonard, X.-Y. Fu, R. Aebersold, J. E. Darnell, Jr., and D. E. Levy. 1992. Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins. Mol Cell Biol. 12:3315-3324.
-
(1992)
Mol Cell Biol.
, vol.12
, pp. 3315-3324
-
-
Veals, S.A.1
Schindler, C.2
Leonard, D.3
Fu, X.-Y.4
Aebersold, R.5
Darnell Jr., J.E.6
Levy, D.E.7
-
30
-
-
0026632288
-
A protein tyrosine kinase in the interferon α/β signalling pathway
-
Velazquez, L., M. Fellows, G. R. Stark, and S. Pellegrini. 1992. A protein tyrosine kinase in the interferon α/β signalling pathway. Cell 70:313-322.
-
(1992)
Cell
, vol.70
, pp. 313-322
-
-
Velazquez, L.1
Fellows, M.2
Stark, G.R.3
Pellegrini, S.4
-
31
-
-
0026698924
-
Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylared peptides
-
Waksman, G., D. Kominos, S. R. Robertson, N. Pant, D. Baltimore, R. B. Birge, D. Cowburn, H. Hanafuaa, B. J. Mayer, M. Overduin, M. D. Resh, C. B. Rios, L. Silverman, and J. Kuriyan. 1992 Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylared peptides. Nature (London) 358:646-653.
-
(1992)
Nature (London)
, vol.358
, pp. 646-653
-
-
Waksman, G.1
Kominos, D.2
Robertson, S.R.3
Pant, N.4
Baltimore, D.5
Birge, R.B.6
Cowburn, D.7
Hanafuaa, H.8
Mayer, B.J.9
Overduin, M.10
Resh, M.D.11
Rios, C.B.12
Silverman, L.13
Kuriyan, J.14
-
32
-
-
0027914818
-
Complementation by the protein tyrosine kinase Jak2 of a mutant cell line defective in the interferon-γ signal transduction pathwav
-
Watling, D., D. Gushin, M. Muller, O. Silvennoinen, B. A. Witthuhn, F. W. Quelle, N. C. Rogers, C. Schindler, G. R. Stark, J. N. Ihle, and I. M. Kerr. 1993 Complementation by the protein tyrosine kinase Jak2 of a mutant cell line defective in the interferon-γ signal transduction pathwav. Nature (London) 366:166-170.
-
(1993)
Nature (London)
, vol.366
, pp. 166-170
-
-
Watling, D.1
Gushin, D.2
Muller, M.3
Silvennoinen, O.4
Witthuhn, B.A.5
Quelle, F.W.6
Rogers, N.C.7
Schindler, C.8
Stark, G.R.9
Ihle, J.N.10
Kerr, I.M.11
-
33
-
-
0029117304
-
Maximal activation of transcription of Stat1 and Stat3 requires both tyrosine and serine phosphorylation
-
Wen, Z., Z. Zhong, and J. E. Darnell, Jr. 1995 Maximal activation of transcription of Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82:241-250.
-
(1995)
Cell
, vol.82
, pp. 241-250
-
-
Wen, Z.1
Zhong, Z.2
Darnell Jr., J.E.3
|