A small amphipathic α-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5

EMBO Journal

Volumn 19, Issue 3, 2000, Pages 392-399

  Wang, Demin ^a   Moriggl, Richard ^a   Stravopodis, Dimitrios ^a   Carpino, Nick ^a   Marine, Jean Christophe ^a   Teglund, Stephan ^a,c   Feng, Jian ^a,d   Ihle, James N ^a,b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

^d ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Downregulation; Proteasome; Stat proteins; Transcription

Indexed keywords

MUTANT PROTEIN; PHOSPHOTYROSINE; PROTEASOME; STAT1 PROTEIN; STAT2 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN;

ALPHA HELIX; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION;

ACETYLCYSTEINE; ANIMALS; CELL LINE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DNA-BINDING PROTEINS; LEUPEPTINS; MILK PROTEINS; MULTIENZYME COMPLEXES; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STRUCTURE, SECONDARY; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TYROSINE;

ANIMALIA; EUKARYOTA;

EID: 0034142208     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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