Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNγ-mediated signaling

Cell

Volumn 96, Issue 1, 1999, Pages 121-130

  Zhu, Ming Hua ^a   John, Susan ^a   Berg, Maria ^a   Leonard, Warren J ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; STAT1 PROTEIN; STAT5 PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; HUMAN; HUMAN CELL; IMMUNOREGULATION; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALIA;

EID: 0033534562     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80965-4     Document Type: Article

References (62)

1. Azam, M., Erdjument-Biomage, H., Kreider, B.L., Xia, M., Quelle, F., Basu, R., Saris, C., Tempst, P., Ihle, J.N., and Schindler, C. (1995). Interleukin-3 signals through multiple isoforms of Stat5. EMBO J. 14, 1402-1411.
2. Bannister, A.J., and Kouzarides, T. (1996). The CBP co-activator is a histone acetyltransferase. Nature 384, 641-643.
3. Bao, J., and Zervos, A.S. (1996). Isolation and characterization of Nmi, a novel partner of Myc proteins. Oncogene 12, 2171-2176.
4. Becker, S., Groner, B., and Müller, C.W. (1998). Three-dimensional structure of the Stat3 β homodimer bound to DNA. Nature 394, 145-151.
5. Bhattacharya, S., Eckner, R., Grossman, S., Oldread, E., Arany, Z., D'Andrea, A., and Livingston, D.M. (1996). Cooperation of Stat2 and p300 CBP in signaling induced by Interferon-α. Nature 383, 344-347.
6. c chain of the IL-2 receptor. Science 266, 1039-1042.
7. Cella, N., Groner, B., and Hynes, N.E. (1998). Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocorticoid receptor in mammary cells. Mol. Cell. Biol. 18, 1783-1792.
8. Chakravarti, D., LaMorte, V.J., Nelson, M.C., Nakajima,T., Schulman, I.G., Juguilon, H., Montminy, M., and Evans, R.M. (1996). Role of CBP/P300 in nuclear receptor signaling. Nature 383, 99-103.
9. Chen, M., Cheng, A., Chen, Y.Q., Hymel, A., Hanson, E.P., Kimmel, L., Minami, Y., Taniguchi, T., Changelian, P.S., and O'Shea, J.J. (1997). The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals. Proc. Natl. Acad. Sci. USA 94, 6910-6915.
10. Chen, X., Vinkemeier, U., Zhao, Y., Jeruzalmi, D., Darnell, J.E., Jr., and Kuriyan, J. (1998). Crystal structure of a tyrosine phosphorylated STAT 1 dimer bound to DNA. Cell 93, 827-839.
11. Chung, C.D., Liao, J., Liu, B., Rao, X., Jay, P., Berta, P., and Shuai, K. (1997). Specific inhibition of Stat3 signal transduction by PIAS3. Science 278, 1803-1805.
12. Darnell, J.E., Jr. (1997). STATs and gene regulation. Science 277, 1630-1636.
13. Durfee, T., Becherer, K., Chen, P.-L, Yeh, S.-H., Yang, Y., Kilburn, A.E., Lee, W.-H., and Elledge, S.J. (1993). The retinoblastoma protein associates with the protein phosphatase type I catalytic subunit. Genes Dev. 7, 555-569.
14. Eckner, R., Yao, T.-P., Oldread, E., and Livingston, D.M. (1996). Interaction and functional collaboration of p300 CBP and bHLH proteins in muscle and B-cell differentiation. Genes Dev. 10, 2478-2490.
15. Fu, X.-Y., Kessler, D.S., Veals, S.A., Levy, D.E., and Darnell, J.E., Jr. (1990). ISGF3, the transcriptional activator induced by Interferon alpha, consists of multiple interacting polypeptide chains. Proc. Natl. Acad. Sci. USA 87, 8555-8559.
16. Fujii, H., Nakagawa, Y., Schindler, U., Kawahara, A., Mori, H., Gouilleux, F., Groner, B., Ihle, J.N., Minami, Y., Miyazaki, T., and Taniguchi, T. (1995). Activation of Stats by interleukin 2 requires a carboxylterminal region of the interleukin 2 receptor β chain but is not essential for the proliferative signal transmission. Proc. Natl. Acad. Sci. USA 92, 5482-5486.
17. Gaffen, S.L., Lai, S.Y., Xu, W., Gouilleux, F., Groner, B., Goldsmith, M.A., and Greene, W.C. (1995). Signaling through the interleukin 2 receptor β chain activates a STAT-5-like DNA-binding activity. Proc. Natl. Acad. Sci. USA 92, 7192-7196.
18. Gilmour, K., Pine, R., and Reich, N.C. (1995). Interleukin 2 activates STAT5 transcription factor (mammary gland factor) and specific gene expression in T lymphocytes. Proc. Natl. Acad. Sci. USA 92, 10772-10776.
19. Gu, W., Shi, X.-L, and Roeder, R.G. (1997). Synergistic activation of transcription by CBP and p53. Nature 387, 819-823.
20. Horvai, A.E., Xu, L., Korzus, E., Brard, G., Kalafus, D., Mullen, T.-M., Rose, D.W., Rosenfeld, M.G., and Glass, C.K. (1997). Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc. Natl. Acad. Sci. USA 94, 1074-1079.
21. Horvath, C.M., Stark, G.R., Kerr, I.M., and Darnell, J.E., Jr. (1996). Interactions between STAT and non-STAT proteins in the ISGF3 complex. Mol. Cell. Biol. 16, 6957-6964.
22. Hou, J., Schindler, U., Henzel, W.J., Wong, S.C., and McKnight, S.L. (1995). Identification and purification of human Stat proteins activated in response to inter leukin-2. Immunity 2, 321-329.
23. Ihle, J.N. (1996). STATs: signal transducers and activators of transcription. Cell 84, 331-334.
24. Imada, K., Bloom, E.T., Nakajima, H., Horvath-Arcidiacono, J.A., Udy, G.B., Davey, H., and Leonard, W.J. (1998). Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity. J. Exp. Med. 188, 2067-2074.
25. Janknecht, R., and Hunter, T. (1996). Transcriptional control: versatile molecular glue. Curr. Biol. 6, 951-954.
26. John, S., Reeves, R.B., Lin, J.-X., Child, R., Leiden, J.M., Thompson, C.B., and Leonard, W.J. (1995). Regulation of cell-type-specific interleukin-2 receptor α chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-κB family proteins. Mol. Cell. Biol. 15, 1786-1796.
27. John, S., Robbins, C.M., and Leonard, W.J. (1996). An IL-2 response element in the human IL-2 receptor α chain promoter is a composite element that binds Stat5, Elf-1, HMG-I(Y) and a GATA family protein. EMBO J. 15, 5627-5635.
28. John, S., Vinkemeier, U., Soldaini, E., Darnell, J.E., Jr., and Leonard, W.J. (1999). The significance of tetramerization in promoter recruitment by Stat5. Mol. Cell. Biol., in press.
29. Lecine, P., Algarte, M., Rameil, P., Beadling, C., Bucher, P., Nabholz, M., and Imbert, J. (1996). Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor α gene. Mol. Cell. Biol. 16, 6829-6840.
30. Leonard, W.J., and O'Shea, J.J. (1998). Jaks and STATs: biological implications. Annu. Rev. Immunol. 16, 293-322.
31. Lill, N.L., Grossman, S.R., Ginsberg, D., DeCaprio, J., and Livingston, D.M. (1997). Binding and modulation of p53 by p300 CBP coactivators. Nature 387, 823-827.
32. Lin, J.-X., and Leonard, W.J. (1997). Signaling from the IL-2 receptor to the nucleus. Cyt. Growth Factor Rev. 8, 313-332.
33. Lin J.-X., Migone, T.S., Tsang, M., Friedmann, M., Weatherbee, J.A., Zhou, L., Yamauchi, A., Bloom, E.T., Mietz, J., John, S., and Leonard, W.J. (1995). The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 2, 331-339.
34. Lin, J.-X., Mietz, J., Modi, W.S., John, S., and Leonard, W.J. (1996). Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells. J. Biol. Chem. 271, 10738-10744.
35. Liu, X., Robinson, G.W., Wagner, K.-U., Garrett, L., Wynshaw-Boris, A., and Hennighausen, L. (1997). Stat5a is mandatory for adult mammary gland development and lactogenesis. Genes Dev. 11, 179-186.
36. Liu, B., Liao, J., Rao, X., Kushner, S.A., Chung, C.D., Chang, D.D., and Shuai, K. (1998). Inhibition of Stall-mediated gene activation by PIAS1. Proc. Natl. Acad. Sci. USA 95, 10626-10631.
37. Look, D.C., Pelletier, M.R., Tidwell, R.M., Roswit, W.T., and Holtzman, M.J. (1995). Stat1 depends on transcriplional synergy with Sp1. J. Biol. Chem. 270, 30264-30267.
38. Martinez-Moczygemba, M., Gulch, M.J., French, D.L, and Reich, N.C. (1997). Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-α-stimulated transcription factor ISGF3. J. Biol. Chem. 272, 20070-20076.
39. Minami, Y., Oishi, I., Liu, Z.J., Nakagawa, S., Miyazaki, T., and Taniguchi, T. (1994). Signal transduction medialed by the reconstituted IL-2 receptor: evidence for a cell type-specific function of IL-2 receptor β-chain. J. Immunol. 152, 5680-5690.
40. Miyazaki, T., Kawahara, A., Fujii, H., Nakagawa, Y., Minami, Y., Liu, Z.J., Oishi, I., Silvennoinen, O., Witthuhn, B.A., Ihle, J.N., and Taniguchi, T. (1994). Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits. Science 266, 1045-1047.
41. Mui, A.L., Wakao, H., O'Farrell, A.M., Harada, N., and Miyajima, A. (1995). lnterleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologues. EMBO J. 14, 1166-1175.
42. Nakajima, H., Liu, X.W., Wynshaw-Boris, A., Rosenthal, L.A., Imada, K., Finbloom, D.S., Hennighausen, L., and Leonard, W.J. (1997a). An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor α chain induction. Immunity 7, 691-701.
43. Nakajima, T., Uchida, C., Anderson, S.F., Lee, C.G., Hurwitz, J., Parvin, J.D., and Montminy, M. (1997b). RNA helicase A mediates association of CBP with RNA polymerase II. Cell 90, 1107-1112.
44. Nielsen, M., Svejgaard, A., Skov, S., and Odum, N. (1994). Interleukin-2 induces tyrosine phosphorylation and nuclear translocation of Stat3 in human T lymphocytes. Eur. J. Immunol. 24, 3082-3086.
45. Ogryzko, V.V., Schiltz, R.L., Russanova, V., Howard, B.H., and Nakatani, Y. (1996). The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87, 953-959.
46. Pfitzner, E., Jahne, R., Wissler, M., Stoecklin, E., and Groner, B. (1998). p300 CREB-binding protein enhances the prolactin-mediated transcriptional induction through direct interaction with the transactivation domain of Stat5, but does not participate in Stat5-mediated supression of the glucocorticoid response. Mol. Endocrin. 10, 1582-1593.
47. c chains with Jak1 and Jak3: implications for XSCID and XCID. Science 266, 1042-1045.
48. Schaefer, T.S., Sanders, L.K., and Nathans, D. (1995). Cooperative transcriptional activity of Jun and Stat3b, a short form of Stat3. Proc. Natl. Acad. Sci. USA 92, 9097-9101.
49. Sims, S.H., Cha, Y., Romine, M.F., Gao, P.-Q., Gottlieb, K., and Deisseroth, A.B. (1993). A novel interferon-inducible domain: structural and functional analysis of the human Interferon regulatory factor 1 gene promoter. Mol. Cell. Biol. 13, 690-702.
50. Sperisen, P., Wang, S.M., Soldaini, E., Pla, M., Rusterholz, C., Bucher, P., Corthesy, P., Reichenbach, P., and Nabholz, M. (1995). Mouse interleukin-2 receptor aα gene expression: interleukin-1 and interleukin-2 control transcription via distinct cis-acting elements. J. Biol. Chem. 270, 10743-10753.
51. Stocklin, E., Wissler, M., Gouilleux, F., and Groner, B. (1996). Functional interactions between Stat5 and the glucocorticoid receptor. Nature 383, 726-728.
52. Taniguchi, T. (1995). Cytokine signaling through nonreceptor protein tyrosine kinases. Science 268, 251-255.
53. Teglund, S., McKay, C., Shuetz, E., van Duersen, J.M., Stravopodis, D., Wang, D., Brown, M., Bodner, S., Grosveld, G., and Ihle, J.N. (1998). Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell 93, 841-850.
54. Udy, G.B., Towers, R.P., Snell, R.G., Wilkins, R.J., Park, S.-H., Ram, P.A., Waxman, D.J., and Davey, H.W. (1997). Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression. Proc. Natl. Acad. Sci. USA 94, 7239-7244.
55. Vinkemeier, U., Cohen, S.L., Moarefi, L, Chait, B.T., Kuriyan, J., and Darnell, J.E., Jr. (1996). DNA binding of in vitro activated Stat1α, Stal1 β and truncated Stal1 : interaction between NH2-lerminal domains stabilizes binding of two dimers to tandem DNA sites. EMBO J. 15, 5616-5626.
56. Vinkemeier, U., Moarefi, I., Darnell, J.E., Jr, and Kuriyan, J. (1998). Structure of the amino-terminal protein interaction domain of STAT-4. Science 279, 1048-1052.
57. Wen, Z., Zhong, Z., and Darnell, J.E., Jr. (1995). Maximal activation of transcription by Stal1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82, 241-250.
58. Xu, X., Sun, Y.L., and Hoey, T. (1996). Cooperative DNA binding and sequence-selective recognition conferred by the STAT aminoterminal domain. Science 273, 794-797.
59. Yao, T.-P, Oh, S.P., Fuchs, M., Zhou, N.-D., Ch'ng, L-E, Newsome, D., Bronson, R.T., Li, E., Livingston, D.M., and Eckner, R. (1998). Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell 93, 361-372.
60. Zhang, X., Blenis, J., Li, H.C., Schindler, C., and Chen-Kiang, S. (1995). Requirement of serine phosphorylation for formation of STAT-promoter complexes. Science 267, 1990-1994.
61. Zhang, J.J., Vinkemeier, U., Gu, W., Chakravarti, D., Horvath, C.M., and Darnell, J.E., Jr. (1996). Two contact regions between Stal1 and CBP p300 in Interferon gamma signaling. Proc. Natl. Acad. Sci. USA 93, 15092-15096.
62. Zhu, M., Berry, J.A., Russell, S.M., and Leonard, W.J. (1998). Delineation of the regions of interleukin-2 (IL-2) receptor β chain important for association of Jak1 and Jak3. J. Biol. Chem. 273, 10719-10725.