-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D. & Weinberg, R. A. The hallmarks of cancer. Cell 100, 57-70 (2000).
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
0030689735
-
Cancer: What should be done?
-
Bishop, J. M. Cancer: what should be done? Science 278, 995 (1997).
-
(1997)
Science
, vol.278
, pp. 995
-
-
Bishop, J.M.1
-
3
-
-
0027401607
-
The multistep nature of cancer
-
Vogelstein, B. & Kinzler, K. W. The multistep nature of cancer. Trends Genet. 9, 138-141 (1993).
-
(1993)
Trends Genet
, vol.9
, pp. 138-141
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
4
-
-
0036852241
-
-
Dunn, G. P., Bruce, A. T., Ikeda, H., Old, L. J. & Schreiber, R. D. Cancer immunoediting: from immunosurveillance to tumor escape. Nature Immunol. 3, 991-998 (2002). This is an insightful review on the mechanisms of immune surveillance and immune editing of tumours.
-
Dunn, G. P., Bruce, A. T., Ikeda, H., Old, L. J. & Schreiber, R. D. Cancer immunoediting: from immunosurveillance to tumor escape. Nature Immunol. 3, 991-998 (2002). This is an insightful review on the mechanisms of immune surveillance and immune editing of tumours.
-
-
-
-
5
-
-
0042470540
-
Does the immune system see tumors as foreign or self?
-
Pardoll, D. Does the immune system see tumors as foreign or self? Annu. Rev. Immunol. 21, 807-839 (2003).
-
(2003)
Annu. Rev. Immunol
, vol.21
, pp. 807-839
-
-
Pardoll, D.1
-
6
-
-
3042844293
-
Cancer immunotherapy: A treatment for the masses
-
Blattman, J. N. & Greenberg, P. D. Cancer immunotherapy: a treatment for the masses. Science 305, 200-205 (2004).
-
(2004)
Science
, vol.305
, pp. 200-205
-
-
Blattman, J.N.1
Greenberg, P.D.2
-
7
-
-
10244279184
-
Mechanisms and functional significance of tumour-induced dendritic-cell defects
-
Gabrilovich, D. Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nature Rev. Immunol. 4, 941-952 (2004).
-
(2004)
Nature Rev. Immunol
, vol.4
, pp. 941-952
-
-
Gabrilovich, D.1
-
8
-
-
16844379997
-
Immunosuppressive networks in the tumour environment and their therapeutic relevance
-
Zou, W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nature Rev. Cancer 5, 263-274 (2005).
-
(2005)
Nature Rev. Cancer
, vol.5
, pp. 263-274
-
-
Zou, W.1
-
10
-
-
0347123433
-
Tumour-educated macrophages promote tumour progression and metastasis
-
Pollard, J. W. Tumour-educated macrophages promote tumour progression and metastasis. Nature Rev. Cancer 4, 71-78 (2004).
-
(2004)
Nature Rev. Cancer
, vol.4
, pp. 71-78
-
-
Pollard, J.W.1
-
11
-
-
0029069540
-
-
Yu, C. L. et al. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 269, 81-83 (1995). This study provides the first evidence that STAT3 has a role in oncogenesis in that STAT3 is constitutively activated by SRC oncoprotein.
-
Yu, C. L. et al. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 269, 81-83 (1995). This study provides the first evidence that STAT3 has a role in oncogenesis in that STAT3 is constitutively activated by SRC oncoprotein.
-
-
-
-
12
-
-
0034657336
-
The role of STATs in transcriptional control and their impact on cellular function
-
Bromberg, J. & Darnell, J. E. The role of STATs in transcriptional control and their impact on cellular function. Oncogene 19, 2468-2473 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 2468-2473
-
-
Bromberg, J.1
Darnell, J.E.2
-
13
-
-
1042302005
-
-
Yu, H. & Jove, R. The STATs of cancer - new molecular targets come of age. Nature Rev. Cancer 4, 97-105 (2004). A comprehensive review on the role of STAT3 in cancer progression and on STAT3 as a target for cancer therapy.
-
Yu, H. & Jove, R. The STATs of cancer - new molecular targets come of age. Nature Rev. Cancer 4, 97-105 (2004). A comprehensive review on the role of STAT3 in cancer progression and on STAT3 as a target for cancer therapy.
-
-
-
-
14
-
-
0033034365
-
H1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
-
H1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 10, 39-49 (1999).
-
(1999)
Immunity
, vol.10
, pp. 39-49
-
-
Takeda, K.1
-
15
-
-
0037452789
-
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunity
-
Welte, T. et al. STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc. Natl Acad. Sci. USA 100, 1879-1884 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 1879-1884
-
-
Welte, T.1
-
16
-
-
11144357779
-
-
H1-type immune-stimulating molecules, it also promotes the expression of immunosuppressive factors, leading to the inhibition of DC maturation.
-
H1-type immune-stimulating molecules, it also promotes the expression of immunosuppressive factors, leading to the inhibition of DC maturation.
-
-
-
-
17
-
-
28644445445
-
-
Kortylewski, M. et al. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nature Med. 11, 1314-1321 (2005). This study shows that STAT3 is constitutively activated in diverse immune-cell subsets in the tumour microenvironment. STAT3 signalling allows tumour cells and local immune cells to resonate with one another, leading to immunosuppression.
-
Kortylewski, M. et al. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nature Med. 11, 1314-1321 (2005). This study shows that STAT3 is constitutively activated in diverse immune-cell subsets in the tumour microenvironment. STAT3 signalling allows tumour cells and local immune cells to resonate with one another, leading to immunosuppression.
-
-
-
-
18
-
-
27944479710
-
-
Nabarro, S. et al. Coordinated oncogenic transformation and inhibition of host immune responses by the PAX3-FKHR fusion oncoprotein. J. Exp. Med. 202, 1399-1410 (2005). This paper shows that activation of STAT3 by an oncoprotein inhibits the host immune response in mouse models.
-
Nabarro, S. et al. Coordinated oncogenic transformation and inhibition of host immune responses by the PAX3-FKHR fusion oncoprotein. J. Exp. Med. 202, 1399-1410 (2005). This paper shows that activation of STAT3 by an oncoprotein inhibits the host immune response in mouse models.
-
-
-
-
19
-
-
33745859743
-
-
Sumimoto, H., Imabayashi, F., Iwata, T. & Kawakami, Y. The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells. J. Exp. Med. 203, 1651-1656 (2006). Results from this paper show that both STAT3 activation and the BRAF-MAPK signalling pathway can promote the expression of immunosuppressive factors such as IL-6, IL-10 and VEGF in human melanoma cells. Blocking either of these oncogenic signalling pathways in DCs decreases tumour-factor-induced inhibition of IL-12 expression.
-
Sumimoto, H., Imabayashi, F., Iwata, T. & Kawakami, Y. The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells. J. Exp. Med. 203, 1651-1656 (2006). Results from this paper show that both STAT3 activation and the BRAF-MAPK signalling pathway can promote the expression of immunosuppressive factors such as IL-6, IL-10 and VEGF in human melanoma cells. Blocking either of these oncogenic signalling pathways in DCs decreases tumour-factor-induced inhibition of IL-12 expression.
-
-
-
-
20
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell, J. E., Kerr, I. M. & Stark, G. R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264, 1415-1421 (1994).
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell, J.E.1
Kerr, I.M.2
Stark, G.R.3
-
21
-
-
0030890718
-
Gp130 and the interleukin-6 family of cytokines
-
Taga, T. & Kishimoto, T. Gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol. 15, 797-819 (1997).
-
(1997)
Annu. Rev. Immunol
, vol.15
, pp. 797-819
-
-
Taga, T.1
Kishimoto, T.2
-
22
-
-
0032168152
-
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
-
Heinrich, P. C., Behrmann, I., Muller-Newen, G., Schaper, F. & Graeve, L. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem. J. 334, 297-314 (1998).
-
(1998)
Biochem. J
, vol.334
, pp. 297-314
-
-
Heinrich, P.C.1
Behrmann, I.2
Muller-Newen, G.3
Schaper, F.4
Graeve, L.5
-
23
-
-
0031821617
-
Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway
-
Darnell, J. E. Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway. J. Interferon Cytokine Res. 18, 549-554 (1998).
-
(1998)
J. Interferon Cytokine Res
, vol.18
, pp. 549-554
-
-
Darnell, J.E.1
-
24
-
-
0031657551
-
How cells respond to interferons
-
Stark, G. R., Kerr, I. M., Williams, B. R., Silverman, R. H. & Schreiber, R. D. How cells respond to interferons. Annu. Rev. Biochem. 67, 227-264 (1998).
-
(1998)
Annu. Rev. Biochem
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.3
Silverman, R.H.4
Schreiber, R.D.5
-
25
-
-
0041677606
-
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
-
Heinrich, P. C. et al. Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem. J. 374, 1-20 (2003).
-
(2003)
Biochem. J
, vol.374
, pp. 1-20
-
-
Heinrich, P.C.1
-
26
-
-
15744385061
-
Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation
-
Wang, R., Cherukuri, P. & Luo, J. Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation. J. Biol. Chem. 280, 11528-11534 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 11528-11534
-
-
Wang, R.1
Cherukuri, P.2
Luo, J.3
-
27
-
-
12244251445
-
Stat3 dimerization regulated by reversible acetylation of a single lysine residue
-
Yuan, Z. L., Guan, Y. J., Chatterjee, D. & Chin, Y. E. Stat3 dimerization regulated by reversible acetylation of a single lysine residue. Science 307, 269-273 (2005).
-
(2005)
Science
, vol.307
, pp. 269-273
-
-
Yuan, Z.L.1
Guan, Y.J.2
Chatterjee, D.3
Chin, Y.E.4
-
28
-
-
0027371337
-
Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation
-
Silvennoinen, O., Schindler, C., Schlessinger, J. & Levy, D. E. Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation. Science 261, 1736-1739 (1993).
-
(1993)
Science
, vol.261
, pp. 1736-1739
-
-
Silvennoinen, O.1
Schindler, C.2
Schlessinger, J.3
Levy, D.E.4
-
29
-
-
0028349735
-
Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
-
Zhong, Z., Wen, Z. & Darnell, J. E. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 264, 95-98 (1994).
-
(1994)
Science
, vol.264
, pp. 95-98
-
-
Zhong, Z.1
Wen, Z.2
Darnell, J.E.3
-
30
-
-
0028085525
-
Epidermal growth factor and lipopolysaccharide activate Stat3 transcription factor in mouse liver
-
Ruff-Jamison, S. et al. Epidermal growth factor and lipopolysaccharide activate Stat3 transcription factor in mouse liver. J. Biol. Chem. 269, 21933-21935 (1994).
-
(1994)
J. Biol. Chem
, vol.269
, pp. 21933-21935
-
-
Ruff-Jamison, S.1
-
31
-
-
0036595049
-
Suppressors of cytokine signalling (SOCS) in the immune system
-
Alexander, W. S. Suppressors of cytokine signalling (SOCS) in the immune system. Nature Rev. Immunol. 2, 410-416 (2002).
-
(2002)
Nature Rev. Immunol
, vol.2
, pp. 410-416
-
-
Alexander, W.S.1
-
32
-
-
0346121599
-
Suppressors of cytokine signaling and immunity
-
Kubo, M., Hanada, T. & Yoshimura, A. Suppressors of cytokine signaling and immunity. Nature Immunol. 4, 1169-1176 (2003).
-
(2003)
Nature Immunol
, vol.4
, pp. 1169-1176
-
-
Kubo, M.1
Hanada, T.2
Yoshimura, A.3
-
33
-
-
23444461182
-
Regulation of gene-activation pathways by PIAS proteins in the immune system
-
Shuai, K. & Liu, B. Regulation of gene-activation pathways by PIAS proteins in the immune system. Nature Rev. Immunol. 5, 593-605 (2005).
-
(2005)
Nature Rev. Immunol
, vol.5
, pp. 593-605
-
-
Shuai, K.1
Liu, B.2
-
34
-
-
0031953831
-
Stat3 activation by Src induces specific gene regulation and is required for cell transformation
-
Turkson, J. et al. Stat3 activation by Src induces specific gene regulation and is required for cell transformation. Mol. Cell. Biol. 18, 2545-2552 (1998).
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 2545-2552
-
-
Turkson, J.1
-
35
-
-
0031893214
-
Stat3 activation is required for cellular transformation by v-src
-
Bromberg, J. F., Horvath, C. M., Besser, D., Lathem, W. W. & Darnell, J. E. Stat3 activation is required for cellular transformation by v-src. Mol. Cell. Biol. 18, 2553-2558 (1998).
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 2553-2558
-
-
Bromberg, J.F.1
Horvath, C.M.2
Besser, D.3
Lathem, W.W.4
Darnell, J.E.5
-
36
-
-
0033529704
-
-
Bromberg, J. F. et al. Stat3 as an oncogene. Cell 98, 295-303 (1999). Using a constitutively active mutant form of STAT3, this study formally establishes that STAT3 is an oncoprotein.
-
Bromberg, J. F. et al. Stat3 as an oncogene. Cell 98, 295-303 (1999). Using a constitutively active mutant form of STAT3, this study formally establishes that STAT3 is an oncoprotein.
-
-
-
-
37
-
-
0032984589
-
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
-
Catlett-Falcone, R. et al. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity 10, 105-115 (1999).
-
(1999)
Immunity
, vol.10
, pp. 105-115
-
-
Catlett-Falcone, R.1
-
38
-
-
0013689209
-
Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor-mediated cell growth in vitro
-
Grandis, J. R. et al. Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor-mediated cell growth in vitro. J. Clin. Invest. 102, 1385-1392 (1998).
-
(1998)
J. Clin. Invest
, vol.102
, pp. 1385-1392
-
-
Grandis, J.R.1
-
39
-
-
0034658551
-
The role of STATs in myeloid differentiation and leukemia
-
Coffer, P. J., Koenderman, L. & de Groot, R. P. The role of STATs in myeloid differentiation and leukemia. Oncogene 19, 2511-2522 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 2511-2522
-
-
Coffer, P.J.1
Koenderman, L.2
de Groot, R.P.3
-
40
-
-
0034658153
-
STAT signaling in the pathogenesis and treatment of leukemias
-
Lin, T. S., Mahajan, S. & Frank, D. A. STAT signaling in the pathogenesis and treatment of leukemias. Oncogene 19, 2496-2504 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 2496-2504
-
-
Lin, T.S.1
Mahajan, S.2
Frank, D.A.3
-
41
-
-
21544473172
-
Targeting STAT3 affects melanoma on multiple fronts
-
Kortylewski, M., Jove, R. & Yu, H. Targeting STAT3 affects melanoma on multiple fronts. Cancer Metastasis Rev. 24, 315-327 (2005).
-
(2005)
Cancer Metastasis Rev
, vol.24
, pp. 315-327
-
-
Kortylewski, M.1
Jove, R.2
Yu, H.3
-
42
-
-
0032718891
-
Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo
-
Niu, G. et al. Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo. Cancer Res. 59, 5059-5063 (1999).
-
(1999)
Cancer Res
, vol.59
, pp. 5059-5063
-
-
Niu, G.1
-
43
-
-
0035870249
-
Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest
-
Niu, G. et al. Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest. Cancer Res. 61, 3276-3280 (2001).
-
(2001)
Cancer Res
, vol.61
, pp. 3276-3280
-
-
Niu, G.1
-
44
-
-
85047695527
-
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
-
Niu, G. et al. Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene 21, 2000-2008 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 2000-2008
-
-
Niu, G.1
-
45
-
-
0037461934
-
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis
-
Wei, D. et al. Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. Oncogene 22, 319-329 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 319-329
-
-
Wei, D.1
-
46
-
-
0037435011
-
Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway
-
Wei, L. H. et al. Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway. Oncogene 22, 1517-1527 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 1517-1527
-
-
Wei, L.H.1
-
47
-
-
24644457736
-
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
-
Xu, Q. et al. Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways. Oncogene 24, 5552-5560 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 5552-5560
-
-
Xu, Q.1
-
48
-
-
33646557679
-
A novel activating function of c-Src and Stat3 on HGF transcription in mammary carcinoma cells
-
Wojcik, E. J. et al. A novel activating function of c-Src and Stat3 on HGF transcription in mammary carcinoma cells. Oncogene 25, 2773-2784 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 2773-2784
-
-
Wojcik, E.J.1
-
49
-
-
2442685645
-
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis
-
Xie, T. X. et al. Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis. Oncogene 23, 3550-3560 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 3550-3560
-
-
Xie, T.X.1
-
50
-
-
3242676769
-
Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C
-
Dechow, T. N. et al. Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C. Proc. Natl Acad. Sci. USA 101, 10602-10607 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 10602-10607
-
-
Dechow, T.N.1
-
51
-
-
20144376844
-
Stat3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects
-
Burdelya, L. et al. Stat3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects. J. Immunol. 174, 3925-3931 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 3925-3931
-
-
Burdelya, L.1
-
52
-
-
0036153123
-
Tumour escape from immune surveillance through dendritic cell inactivation
-
Vicari, A. P., Caux, C. & Trinchieri, G. Tumour escape from immune surveillance through dendritic cell inactivation. Semin. Cancer Biol. 12, 33-42 (2002).
-
(2002)
Semin. Cancer Biol
, vol.12
, pp. 33-42
-
-
Vicari, A.P.1
Caux, C.2
Trinchieri, G.3
-
53
-
-
0042971652
-
Tolerogenic dendritic cells
-
Steinman, R. M., Hawiger, D. & Nussenzweig, M. C. Tolerogenic dendritic cells. Annu. Rev. Immunol. 21, 685-711 (2003).
-
(2003)
Annu. Rev. Immunol
, vol.21
, pp. 685-711
-
-
Steinman, R.M.1
Hawiger, D.2
Nussenzweig, M.C.3
-
54
-
-
0347364683
-
Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer
-
Nefedova, Y. et al. Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer. J. Immunol. 172, 464-474 (2004).
-
(2004)
J. Immunol
, vol.172
, pp. 464-474
-
-
Nefedova, Y.1
-
55
-
-
4644249098
-
IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation
-
Park, S. J. et al. IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation. J. Immunol. 173, 3844-3854 (2004).
-
(2004)
J. Immunol
, vol.173
, pp. 3844-3854
-
-
Park, S.J.1
-
56
-
-
30444443121
-
Regulation of dendritic cell maturation and function by Bruton's tyrosine kinase via IL-10 and Stat3
-
Kawakami, Y. et al. Regulation of dendritic cell maturation and function by Bruton's tyrosine kinase via IL-10 and Stat3. Proc. Natl Acad. Sci. USA 103, 153-158 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 153-158
-
-
Kawakami, Y.1
-
57
-
-
0141790820
-
A critical role for Stat3 signaling in immune tolerance
-
Cheng, F. et al. A critical role for Stat3 signaling in immune tolerance. Immunity 19, 425-436 (2003).
-
(2003)
Immunity
, vol.19
, pp. 425-436
-
-
Cheng, F.1
-
58
-
-
33644775602
-
An oligonucleotide decoy for Stat3 activates the immune response of macrophages to breast cancer
-
Sun, Z., Yao, Z., Liu, S., Tang, H. & Yan, X. An oligonucleotide decoy for Stat3 activates the immune response of macrophages to breast cancer. Immunobiology 211, 199-209 (2006).
-
(2006)
Immunobiology
, vol.211
, pp. 199-209
-
-
Sun, Z.1
Yao, Z.2
Liu, S.3
Tang, H.4
Yan, X.5
-
59
-
-
15444377017
-
+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors
-
+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors. J. Exp. Med. 201, 779-791 (2005).
-
(2005)
J. Exp. Med
, vol.201
, pp. 779-791
-
-
Yu, P.1
-
60
-
-
25444439253
-
+ regulatory T cells in antitumor immune response
-
+ regulatory T cells in antitumor immune response. J. Immunol. 175, 4433-4440 (2005).
-
(2005)
J. Immunol
, vol.175
, pp. 4433-4440
-
-
Nishikawa, H.1
-
61
-
-
33751371759
-
+ regulatory T cell suppression of dendritic cell function involves TGF-β and IL-10
-
+ regulatory T cell suppression of dendritic cell function involves TGF-β and IL-10. Cancer Immunol. Immunother. 56, 48-59 (2007).
-
(2007)
Cancer Immunol. Immunother
, vol.56
, pp. 48-59
-
-
Larmonier, N.1
-
62
-
-
0036721629
-
Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
-
Liyanage, U. K. et al. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J. Immunol. 169, 2756-2761 (2002).
-
(2002)
J. Immunol
, vol.169
, pp. 2756-2761
-
-
Liyanage, U.K.1
-
63
-
-
0035874949
-
+ T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
-
+ T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res. 61, 4766-4772 (2001).
-
(2001)
Cancer Res
, vol.61
, pp. 4766-4772
-
-
Woo, E.Y.1
-
64
-
-
33645286546
-
-
Zou, W. Regulatory T cells, tumour immunity and immunotherapy. Nature Rev. Immunol. 6, 295-307 (2006).
-
Zou, W. Regulatory T cells, tumour immunity and immunotherapy. Nature Rev. Immunol. 6, 295-307 (2006).
-
-
-
-
65
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel, T. J. et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nature Med. 10, 942-949 (2004).
-
(2004)
Nature Med
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
-
66
-
-
20444485236
-
+ regulatory T cells in human ovarian carcinoma
-
+ regulatory T cells in human ovarian carcinoma. Cancer Res. 65, 5020-5026 (2005).
-
(2005)
Cancer Res
, vol.65
, pp. 5020-5026
-
-
Wei, S.1
-
67
-
-
16844365788
-
+ regulatory T cells in immunological tolerance to self and non-self
-
+ regulatory T cells in immunological tolerance to self and non-self. Nature Immunol. 6, 345-352 (2005).
-
(2005)
Nature Immunol
, vol.6
, pp. 345-352
-
-
Sakaguchi, S.1
-
68
-
-
0036597371
-
-
+ suppressor T cells: more questions than answers. Nature Rev. Immunol. 2, 389-400 (2002).
-
+ suppressor T cells: more questions than answers. Nature Rev. Immunol. 2, 389-400 (2002).
-
-
-
-
69
-
-
0348223787
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med. 198, 1875-1886 (2003).
-
(2003)
J. Exp. Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
-
70
-
-
2142645808
-
- T cells through Foxp3 induction and down-regulation of Smad7
-
- T cells through Foxp3 induction and down-regulation of Smad7. J. Immunol. 172, 5149-5153 (2004).
-
(2004)
J. Immunol
, vol.172
, pp. 5149-5153
-
-
Fantini, M.C.1
-
71
-
-
33645849231
-
-
Reg cells.
-
Reg cells.
-
-
-
-
72
-
-
33745587303
-
Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3
-
Kasprzycka, M., Marzec, M., Liu, X., Zhang, Q. & Wasik, M. A. Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3. Proc. Natl Acad. Sci. USA 103, 9964-9969 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 9964-9969
-
-
Kasprzycka, M.1
Marzec, M.2
Liu, X.3
Zhang, Q.4
Wasik, M.A.5
-
73
-
-
20144375594
-
Reg development and function during allergic airway inflammation in vivo
-
Reg development and function during allergic airway inflammation in vivo. J. Clin. Invest. 115, 313-325 (2005).
-
(2005)
J. Clin. Invest
, vol.115
, pp. 313-325
-
-
Doganci, A.1
-
74
-
-
33747801470
-
-
Reg cells is mediated by STAT3 and STAT5.
-
Reg cells is mediated by STAT3 and STAT5.
-
-
-
-
76
-
-
0242580058
-
Loss of tolerance and autoimmunity affecting multiple organs in STAT5A/5B-deficient mice
-
Snow, J. W. et al. Loss of tolerance and autoimmunity affecting multiple organs in STAT5A/5B-deficient mice. J. Immunol. 171, 5042-5050 (2003).
-
(2003)
J. Immunol
, vol.171
, pp. 5042-5050
-
-
Snow, J.W.1
-
77
-
-
11144256544
-
Protein microarrays for multiplex analysis of signal transduction pathways
-
Chan, S. M., Ermann, J., Su, L., Fathman, C. G. & Utz, P. J. Protein microarrays for multiplex analysis of signal transduction pathways. Nature Med. 10, 1390-1396 (2004).
-
(2004)
Nature Med
, vol.10
, pp. 1390-1396
-
-
Chan, S.M.1
Ermann, J.2
Su, L.3
Fathman, C.G.4
Utz, P.J.5
-
78
-
-
19944387916
-
IL-2 overcomes the unresponsiveness but fails to reverse the regulatory function of antigen-induced T regulatory cells
-
Anderson, P. O. et al. IL-2 overcomes the unresponsiveness but fails to reverse the regulatory function of antigen-induced T regulatory cells. J. Immunol. 174, 310-319 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 310-319
-
-
Anderson, P.O.1
-
80
-
-
33746534417
-
IL-23 promotes tumour incidence and growth
-
Langowski, J. L. et al. IL-23 promotes tumour incidence and growth. Nature 442, 461-465 (2006).
-
(2006)
Nature
, vol.442
, pp. 461-465
-
-
Langowski, J.L.1
-
81
-
-
11244348125
-
STAT3 regulates NF-κB recruitment to the IL-12p40 promoter in dendritic cells
-
Hoentjen, F., Sartor, R. B., Ozaki, M. & Jobin, C. STAT3 regulates NF-κB recruitment to the IL-12p40 promoter in dendritic cells. Blood 105, 689-696 (2005).
-
(2005)
Blood
, vol.105
, pp. 689-696
-
-
Hoentjen, F.1
Sartor, R.B.2
Ozaki, M.3
Jobin, C.4
-
82
-
-
33744479688
-
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells
-
Chen, Z. et al. Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells. Proc. Natl Acad. Sci. USA 103, 8137-8142 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 8137-8142
-
-
Chen, Z.1
-
83
-
-
25844459154
-
NF-κB: Linking inflammation and immunity to cancer development and progression
-
Karin, M. & Greten, F. R. NF-κB: linking inflammation and immunity to cancer development and progression. Nature Rev. Immunol. 5, 749-759 (2005).
-
(2005)
Nature Rev. Immunol
, vol.5
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
84
-
-
27744468499
-
Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer
-
Dalwadi, H. et al. Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer. Clin. Cancer Res. 11, 7674-7682 (2005).
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 7674-7682
-
-
Dalwadi, H.1
-
85
-
-
0035953308
-
IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
-
Shankaran, V. et al. IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 410, 1107-1111 (2001).
-
(2001)
Nature
, vol.410
, pp. 1107-1111
-
-
Shankaran, V.1
-
86
-
-
1642619154
-
Induced somatic inactivation of STAT3 in mice triggers the development of a fulminant form of enterocolitis
-
Alonzi, T. et al. Induced somatic inactivation of STAT3 in mice triggers the development of a fulminant form of enterocolitis. Cytokine 26, 45-56 (2004).
-
(2004)
Cytokine
, vol.26
, pp. 45-56
-
-
Alonzi, T.1
-
87
-
-
0035977055
-
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation
-
Turkson, J. et al. Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation. J. Biol. Chem. 276, 45443-45455 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 45443-45455
-
-
Turkson, J.1
-
88
-
-
25444513779
-
A novel platinum compound inhibits constitutive Stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells
-
Turkson, J. et al. A novel platinum compound inhibits constitutive Stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells. J. Biol. Chem. 280, 32979-32988 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 32979-32988
-
-
Turkson, J.1
-
89
-
-
12344328541
-
Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity
-
Turkson, J. et al. Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity. Mol. Cancer Ther. 3, 1533-1542 (2004).
-
(2004)
Mol. Cancer Ther
, vol.3
, pp. 1533-1542
-
-
Turkson, J.1
-
90
-
-
0033517152
-
Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
-
van Elsas, A., Hurwitz, A. A. & Allison, J. P. Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J. Exp. Med. 190, 355-366 (1999).
-
(1999)
J. Exp. Med
, vol.190
, pp. 355-366
-
-
van Elsas, A.1
Hurwitz, A.A.2
Allison, J.P.3
-
91
-
-
11144230063
-
The CD28 family: A T-cell rheostat for therapeutic control of T-cell activation
-
Riley, J. L. & June, C. H. The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation. Blood 105, 13-21 (2005).
-
(2005)
Blood
, vol.105
, pp. 13-21
-
-
Riley, J.L.1
June, C.H.2
-
92
-
-
11144254962
-
Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity
-
Shen, L., Evel-Kabler, K., Strube, R. & Chen, S. Y. Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity. Nature Biotechnol. 22, 1546-1553 (2004).
-
(2004)
Nature Biotechnol
, vol.22
, pp. 1546-1553
-
-
Shen, L.1
Evel-Kabler, K.2
Strube, R.3
Chen, S.Y.4
-
93
-
-
33645853780
-
B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma
-
Kryczek, I. et al. B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma. J. Exp. Med. 203, 871-881 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 871-881
-
-
Kryczek, I.1
-
94
-
-
5044220930
-
IDO expression by dendritic cells: Tolerance and tryptophan catabolism
-
Mellor, A. L. & Munn, D. H. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nature Rev. Immunol. 4, 762-774 (2004).
-
(2004)
Nature Rev. Immunol
, vol.4
, pp. 762-774
-
-
Mellor, A.L.1
Munn, D.H.2
-
95
-
-
4644324025
-
Cancer immunotherapy: Moving beyond current vaccines
-
Rosenberg, S. A., Yang, J. C. & Restifo, N. P. Cancer immunotherapy: moving beyond current vaccines. Nature Med. 10, 909-915 (2004).
-
(2004)
Nature Med
, vol.10
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
96
-
-
0036548986
-
Spinning molecular immunology into successful immunotherapy
-
Pardoll, D. M. Spinning molecular immunology into successful immunotherapy. Nature Rev. Immunol. 2, 227-238 (2002).
-
(2002)
Nature Rev. Immunol
, vol.2
, pp. 227-238
-
-
Pardoll, D.M.1
-
97
-
-
3042722266
-
Immunotherapy: Bewitched, bothered, and bewildered no more
-
Steinman, R. M. & Mellman, I. Immunotherapy: bewitched, bothered, and bewildered no more. Science 305, 197-200 (2004).
-
(2004)
Science
, vol.305
, pp. 197-200
-
-
Steinman, R.M.1
Mellman, I.2
-
98
-
-
0037136303
-
Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody
-
Vicari, A. P. et al. Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody. J. Exp. Med. 196, 541-549 (2002).
-
(2002)
J. Exp. Med
, vol.196
, pp. 541-549
-
-
Vicari, A.P.1
-
99
-
-
27144538568
-
Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway
-
Nefedova, Y. et al. Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway. Cancer Res. 65, 9525-9535 (2005).
-
(2005)
Cancer Res
, vol.65
, pp. 9525-9535
-
-
Nefedova, Y.1
-
100
-
-
27744449724
-
IL-6-STAT3 controls intracellular MHC class II αβ dimer level through cathepsin S activity in dendritic cells
-
Kitamura, H. et al. IL-6-STAT3 controls intracellular MHC class II αβ dimer level through cathepsin S activity in dendritic cells. Immunity 23, 491-502 (2005).
-
(2005)
Immunity
, vol.23
, pp. 491-502
-
-
Kitamura, H.1
-
101
-
-
18844420007
-
Immunotherapy: Target the stroma to hit the tumor
-
Kammertoens, T., Schuler, T. & Blankenstein, T. Immunotherapy: target the stroma to hit the tumor. Trends Mol. Med. 11, 225-231 (2005).
-
(2005)
Trends Mol. Med
, vol.11
, pp. 225-231
-
-
Kammertoens, T.1
Schuler, T.2
Blankenstein, T.3
-
102
-
-
33644757687
-
Tumor evasion of the immune system: Inhibiting p38 MAPK signaling restores the function of dendritic cells in multiple myeloma
-
Wang, S. et al. Tumor evasion of the immune system: inhibiting p38 MAPK signaling restores the function of dendritic cells in multiple myeloma. Blood 107, 2432-2439 (2006).
-
(2006)
Blood
, vol.107
, pp. 2432-2439
-
-
Wang, S.1
-
103
-
-
19444385692
-
Stat3 regulates genes common to both wound healing and cancer
-
Dauer, D. J. et al. Stat3 regulates genes common to both wound healing and cancer. Oncogene 24, 3397-3408 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 3397-3408
-
-
Dauer, D.J.1
-
104
-
-
0033198793
-
Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis
-
Sano, S. et al. Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis. EMBO J. 18, 4657-4668 (1999).
-
(1999)
EMBO J
, vol.18
, pp. 4657-4668
-
-
Sano, S.1
-
105
-
-
20944435271
-
Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target
-
Chiarle, R. et al. Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target. Nature Med. 11, 623-629 (2005).
-
(2005)
Nature Med
, vol.11
, pp. 623-629
-
-
Chiarle, R.1
-
106
-
-
33745919498
-
Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury
-
Okada, S. et al. Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury. Nature Med. 12, 829-834 (2006).
-
(2006)
Nature Med
, vol.12
, pp. 829-834
-
-
Okada, S.1
-
107
-
-
0034604653
-
Full oncogenic activities of v-Src are mediated by multiple signaling pathways. Ras as an essential mediator for cell survival
-
Odajima, J. et al. Full oncogenic activities of v-Src are mediated by multiple signaling pathways. Ras as an essential mediator for cell survival. J. Biol. Chem. 275, 24096-24105 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 24096-24105
-
-
Odajima, J.1
-
109
-
-
0035912763
-
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis
-
Bowman, T. et al. Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis. Proc. Natl Acad. Sci. USA 98, 7319-7324 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 7319-7324
-
-
Bowman, T.1
-
110
-
-
0034676267
-
Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: Role of activated STAT3 signaling
-
Sinibaldi, D. et al. Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling. Oncogene 19, 5419-5427 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 5419-5427
-
-
Sinibaldi, D.1
-
111
-
-
0033584297
-
L expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors
-
L expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors. Oncogene 18, 4654-4662 (1999).
-
(1999)
Oncogene
, vol.18
, pp. 4654-4662
-
-
Karni, R.1
Jove, R.2
Levitzki, A.3
-
112
-
-
0035136846
-
Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression
-
Epling-Burnette, P. K. et al. Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression. J. Clin. Invest. 107, 351-362 (2001).
-
(2001)
J. Clin. Invest
, vol.107
, pp. 351-362
-
-
Epling-Burnette, P.K.1
-
113
-
-
18644380911
-
Roles of activated Src and Stat3 signaling in melanoma tumor cell growth
-
Niu, G. et al. Roles of activated Src and Stat3 signaling in melanoma tumor cell growth. Oncogene 21, 7001-7010 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 7001-7010
-
-
Niu, G.1
-
114
-
-
0037441888
-
Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma
-
Aoki, Y., Feldman, G. M. & Tosato, G. Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma. Blood 101, 1535-1542 (2003).
-
(2003)
Blood
, vol.101
, pp. 1535-1542
-
-
Aoki, Y.1
Feldman, G.M.2
Tosato, G.3
-
115
-
-
3843062504
-
Selective inhibition of STAT3 induces apoptosis and G1 cell cycle arrest in ALK-positive anaplastic large cell lymphoma
-
Amin, H. M. et al. Selective inhibition of STAT3 induces apoptosis and G1 cell cycle arrest in ALK-positive anaplastic large cell lymphoma. Oncogene 23, 5426-5434 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 5426-5434
-
-
Amin, H.M.1
-
116
-
-
31544458469
-
Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells
-
Gritsko, T. et al. Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells. Clin. Cancer Res. 12, 11-19 (2006).
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 11-19
-
-
Gritsko, T.1
-
117
-
-
23844503025
-
Role of Stat3 in regulating p53 expression and function
-
Niu, G. et al. Role of Stat3 in regulating p53 expression and function. Mol. Cell. Biol. 25, 7432-7440 (2005).
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 7432-7440
-
-
Niu, G.1
-
118
-
-
0035853710
-
Co-operative effect of c-Src tyrosine kinase and Stat3 in activation of hepatocyte growth factor expression in mammary carcinoma cells
-
Hung, W. & Elliott, B. Co-operative effect of c-Src tyrosine kinase and Stat3 in activation of hepatocyte growth factor expression in mammary carcinoma cells. J. Biol. Chem. 276, 12395-12403 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 12395-12403
-
-
Hung, W.1
Elliott, B.2
-
119
-
-
33645532055
-
Activation of stat3 in human melanoma promotes brain metastasis
-
Xie, T. X. et al. Activation of stat3 in human melanoma promotes brain metastasis. Cancer Res. 66, 3188-3196 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 3188-3196
-
-
Xie, T.X.1
-
120
-
-
23444449093
-
STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells
-
Jung, J. E. et al. STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells. FASEB J. 19, 1296-1298 (2005).
-
(2005)
FASEB J
, vol.19
, pp. 1296-1298
-
-
Jung, J.E.1
-
121
-
-
1642334206
-
Recruitment of STAT3 for production of IL-10 by colon carcinoma cells induced by macrophage-derived IL-6
-
Herbeuval, J. P., Lelievre, E., Lambert, C., Dy, M. & Genin, C. Recruitment of STAT3 for production of IL-10 by colon carcinoma cells induced by macrophage-derived IL-6. J. Immunol. 172, 4630-4636 (2004).
-
(2004)
J. Immunol
, vol.172
, pp. 4630-4636
-
-
Herbeuval, J.P.1
Lelievre, E.2
Lambert, C.3
Dy, M.4
Genin, C.5
|