-
1
-
-
0034680825
-
The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia
-
Agani, F. H., P. Pichiule, J. C. Chavez, and J. C. LaManna. 2000. The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia. J. Biol. Chem. 275:35863-35867.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 35863-35867
-
-
Agani, F.H.1
Pichiule, P.2
Chavez, J.C.3
LaManna, J.C.4
-
2
-
-
0018344726
-
The mechanism of reduction of single-site redox proteins by ascorbic acid
-
Al-Ayash, A. I., and M. T. Wilson. 1979. The mechanism of reduction of single-site redox proteins by ascorbic acid. Biochem. J. 177:641-648.
-
(1979)
Biochem. J
, vol.177
, pp. 641-648
-
-
Al-Ayash, A.I.1
Wilson, M.T.2
-
4
-
-
0035341719
-
2 induce apoptosis through Fenton chemistry independent of the cellular thiol state
-
2 induce apoptosis through Fenton chemistry independent of the cellular thiol state. Free Radic. Biol. Med. 30:1008-1018.
-
(2001)
Free Radic. Biol. Med
, vol.30
, pp. 1008-1018
-
-
Antunes, F.1
Cadenas, E.2
-
5
-
-
0034674055
-
2 gradients across biomembranes
-
2 gradients across biomembranes. FEBS Lett. 475:121-126.
-
(2000)
FEBS Lett
, vol.475
, pp. 121-126
-
-
Antunes, F.1
Cadenas, E.2
-
6
-
-
0035826733
-
Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1
-
Arnold, R. S., J. Shi, E. Murad, A. M. Whalen, C. Q. Sun, R. Polavarapu, S. Parthasarathy, J. A. Petros, and J. D. Lambeth. 2001. Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1. Proc. Natl. Acad. Sci. USA 98:5550-5555.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 5550-5555
-
-
Arnold, R.S.1
Shi, J.2
Murad, E.3
Whalen, A.M.4
Sun, C.Q.5
Polavarapu, R.6
Parthasarathy, S.7
Petros, J.A.8
Lambeth, J.D.9
-
7
-
-
33846262003
-
2 signaling in the nigrostriatal dopamine pathway via ATP-sensitive potassium channels: Issues and answers
-
2 signaling in the nigrostriatal dopamine pathway via ATP-sensitive potassium channels: issues and answers. Antioxid. Redox Signal. 9:219-231.
-
(2007)
Antioxid. Redox Signal
, vol.9
, pp. 219-231
-
-
Avshalumov, M.V.L.1
Bao, C.P.J.2
Rice, M.E.3
-
8
-
-
35248871643
-
Mitochondrial oxygen sensing: Regulation of hypoxia-inducible factor by mitochondrial generated reactive oxygen species
-
Bell, E. L., and N. S. Chandel. 2007. Mitochondrial oxygen sensing: regulation of hypoxia-inducible factor by mitochondrial generated reactive oxygen species. Essays Biochem. 43:17-27.
-
(2007)
Essays Biochem
, vol.43
, pp. 17-27
-
-
Bell, E.L.1
Chandel, N.S.2
-
9
-
-
34250745912
-
The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production
-
Bell, E. L., T. A. Klimova, J. Eisenbart, C. T. Moraes, M. P. Murphy, G. R. Budinger, and N. S. Chandel. 2007. The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production. J. Cell Biol. 177:1029-1036.
-
(2007)
J. Cell Biol
, vol.177
, pp. 1029-1036
-
-
Bell, E.L.1
Klimova, T.A.2
Eisenbart, J.3
Moraes, C.T.4
Murphy, M.P.5
Budinger, G.R.6
Chandel, N.S.7
-
10
-
-
34547914798
-
Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia
-
Bell, E. L., T. A. Klimova, J. Eisenbart, P. T. Schumacker, and N. S. Chandel. 2007. Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia. Mol. Cell. Biol. 27:5737-5745.
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 5737-5745
-
-
Bell, E.L.1
Klimova, T.A.2
Eisenbart, J.3
Schumacker, P.T.4
Chandel, N.S.5
-
11
-
-
0023553381
-
Catalase activity in human hepatocellular carcinoma (HCC)
-
Bellisola, G., M. Casaril, G. B. Gabrielli, M. Caraffi, and R. Corrocher. 1987. Catalase activity in human hepatocellular carcinoma (HCC). Clin. Biochem. 20:415-417.
-
(1987)
Clin. Biochem
, vol.20
, pp. 415-417
-
-
Bellisola, G.1
Casaril, M.2
Gabrielli, G.B.3
Caraffi, M.4
Corrocher, R.5
-
12
-
-
0032474834
-
Fenton reagent advanced oxidation of polynuclear aromatic hydrocarbons in water
-
Beltran, F. J., M. Gonzalez, F. J. Rivas, and P. Alvarez. 1998. Fenton reagent advanced oxidation of polynuclear aromatic hydrocarbons in water. Water Air Soil Pollut. 105:685-700.
-
(1998)
Water Air Soil Pollut
, vol.105
, pp. 685-700
-
-
Beltran, F.J.1
Gonzalez, M.2
Rivas, F.J.3
Alvarez, P.4
-
13
-
-
0033435198
-
Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain
-
Bergeron, M., A. Y. Yu, K. E. Solway, G. L. Semenza, and F. R. Sharp. 1999. Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain. Eur. J. Neurosci. 11:4159-4170.
-
(1999)
Eur. J. Neurosci
, vol.11
, pp. 4159-4170
-
-
Bergeron, M.1
Yu, A.Y.2
Solway, K.E.3
Semenza, G.L.4
Sharp, F.R.5
-
14
-
-
0036211764
-
Normobaric hypoxia induces tolerance to focal permanent cerebral ischemia in association with an increased expression of hypoxia-inducible factor-1 and its target genes, erythropoietin and VEGF, in the adult mouse brain
-
Bernaudin, M., A. S. Nedelec, D. Divoux, E. T. MacKenzie, E. Petit, and P. Schumann-Bard. 2002. Normobaric hypoxia induces tolerance to focal permanent cerebral ischemia in association with an increased expression of hypoxia-inducible factor-1 and its target genes, erythropoietin and VEGF, in the adult mouse brain. J. Cereb. Blood Flow Metab. 22:393-403.
-
(2002)
J. Cereb. Blood Flow Metab
, vol.22
, pp. 393-403
-
-
Bernaudin, M.1
Nedelec, A.S.2
Divoux, D.3
MacKenzie, E.T.4
Petit, E.5
Schumann-Bard, P.6
-
15
-
-
33847753534
-
Specific aquaporins facilitate the diffusion of hydrogen peroxide across membranes
-
Bienert, G. P., A. L. Moller, K. A. Kristiansen, A. Schulz, I. M. Moller, J. K. Schjoerring, and T. P. Jahn. 2007. Specific aquaporins facilitate the diffusion of hydrogen peroxide across membranes. J. Biol. Chem. 282:1183-1192.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 1183-1192
-
-
Bienert, G.P.1
Moller, A.L.2
Kristiansen, K.A.3
Schulz, A.4
Moller, I.M.5
Schjoerring, J.K.6
Jahn, T.P.7
-
17
-
-
33846991976
-
Insulin-induced activation of hypoxia-inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase
-
Biswas, S., M. K. Gupta, D. Chattopadhyay, and C. K. Mukhopadhyay. 2007. Insulin-induced activation of hypoxia-inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase. Am. J. Physiol. Heart Circ. Physiol. 292:H758-H566.
-
(2007)
Am. J. Physiol. Heart Circ. Physiol
, vol.292
-
-
Biswas, S.1
Gupta, M.K.2
Chattopadhyay, D.3
Mukhopadhyay, C.K.4
-
18
-
-
0015363173
-
The cellular production of hydrogen peroxide
-
Boveris, A., N. Oshino, and B. Chance. 1972. The cellular production of hydrogen peroxide. Biochem. J. 128:617-630.
-
(1972)
Biochem. J
, vol.128
, pp. 617-630
-
-
Boveris, A.1
Oshino, N.2
Chance, B.3
-
19
-
-
0019829973
-
Differential cytotoxicity of daunomycin in tumour cells is related to glutathione-dependent hydrogen peroxide metabolism
-
Bozzi, A., I. Mavelli, B. Mondovi, R. Strom, and G. Rotilio. 1981. Differential cytotoxicity of daunomycin in tumour cells is related to glutathione-dependent hydrogen peroxide metabolism. Biochem. J. 194:369-372.
-
(1981)
Biochem. J
, vol.194
, pp. 369-372
-
-
Bozzi, A.1
Mavelli, I.2
Mondovi, B.3
Strom, R.4
Rotilio, G.5
-
20
-
-
24144444133
-
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation
-
Brunelle, J. K., E. L. Bell, N. M. Quesada, K. Vercauteren, V. Tiranti, M. Zeviani, R. C. Scarpulla, and N. S. Chandel. 2005. Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation. Cell. Metab. 1:409-414.
-
(2005)
Cell. Metab
, vol.1
, pp. 409-414
-
-
Brunelle, J.K.1
Bell, E.L.2
Quesada, N.M.3
Vercauteren, K.4
Tiranti, V.5
Zeviani, M.6
Scarpulla, R.C.7
Chandel, N.S.8
-
21
-
-
0033528653
-
Hydrogen peroxide, potassium currents, and membrane potential in human endothelial cells
-
Bychkov, R., K. Pieper, C. Ried, M. Milosheva, E. Bychkov, F. C. Luft, and H. Haller. 1999. Hydrogen peroxide, potassium currents, and membrane potential in human endothelial cells. Circulation 99:1719-1725.
-
(1999)
Circulation
, vol.99
, pp. 1719-1725
-
-
Bychkov, R.1
Pieper, K.2
Ried, C.3
Milosheva, M.4
Bychkov, E.5
Luft, F.C.6
Haller, H.7
-
22
-
-
33644620740
-
NO restores HIF-1α hydroxylation during hypoxia: Role of reactive oxygen species
-
Callapina, M., J. Zhou, T. Schmid, R. Kohl, and B. Brune. 2005. NO restores HIF-1α hydroxylation during hypoxia: role of reactive oxygen species. Free Radic. Biol. Med. 39:925-936.
-
(2005)
Free Radic. Biol. Med
, vol.39
, pp. 925-936
-
-
Callapina, M.1
Zhou, J.2
Schmid, T.3
Kohl, R.4
Brune, B.5
-
23
-
-
0031791118
-
Effects of modulators of the production and degradation of hydrogen peroxide on erythropoietin synthesis
-
Canbolat, O., J. Fandrey, and W. Jelkmann. 1998. Effects of modulators of the production and degradation of hydrogen peroxide on erythropoietin synthesis. Respir. Physiol. 114:175-183.
-
(1998)
Respir. Physiol
, vol.114
, pp. 175-183
-
-
Canbolat, O.1
Fandrey, J.2
Jelkmann, W.3
-
24
-
-
0021964203
-
Prooxidant states and tumor promotion
-
Cerutti, P. A. 1985. Prooxidant states and tumor promotion. Science 227:375-381.
-
(1985)
Science
, vol.227
, pp. 375-381
-
-
Cerutti, P.A.1
-
25
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance, B., H. Sies, and A. Boveris. 1979. Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 59:527-605.
-
(1979)
Physiol. Rev
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
27
-
-
27744513341
-
Stabilization of hypoxia-inducible factor-1α by prostacyclin under prolonged hypoxia via reducing reactive oxygen species level in endothelial cells
-
Chang, T. C., C. J. Huang, K. Tam, S. F. Chen, K. T. Tan, M. S. Tsai, T. N. Lin, and S. K. Shyue. 2005. Stabilization of hypoxia-inducible factor-1α by prostacyclin under prolonged hypoxia via reducing reactive oxygen species level in endothelial cells. J. Biol. Chem. 280:36567- 36574.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 36567-36574
-
-
Chang, T.C.1
Huang, C.J.2
Tam, K.3
Chen, S.F.4
Tan, K.T.5
Tsai, M.S.6
Lin, T.N.7
Shyue, S.K.8
-
28
-
-
0033763820
-
Expression of hypoxia-inducible factor-1α in the brain of rats during chronic hypoxia
-
Chavez, J. C., F. Agani, P. Pichiule, and J. C. LaManna. 2000. Expression of hypoxia-inducible factor-1α in the brain of rats during chronic hypoxia. J. Appl. Physiol. 89:1937-1942.
-
(2000)
J. Appl. Physiol
, vol.89
, pp. 1937-1942
-
-
Chavez, J.C.1
Agani, F.2
Pichiule, P.3
LaManna, J.C.4
-
29
-
-
0037109768
-
Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: Potential role of insulin-like growth factor-1
-
Chavez, J. C., and J. C. LaManna. 2002. Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: potential role of insulin-like growth factor-1. J. Ncurosci. 22:8922-8931.
-
(2002)
J. Ncurosci
, vol.22
, pp. 8922-8931
-
-
Chavez, J.C.1
LaManna, J.C.2
-
30
-
-
0035577304
-
Differential expression of manganese superoxide dismutase and catalase in lung cancer
-
Chung-man Ho, J., S. Zheng, S. A. Comhair, C. Farver, and S. C. Erzurum. 2001. Differential expression of manganese superoxide dismutase and catalase in lung cancer. Cancer Res. 61:8578-8585.
-
(2001)
Cancer Res
, vol.61
, pp. 8578-8585
-
-
Chung-man Ho, J.1
Zheng, S.2
Comhair, S.A.3
Farver, C.4
Erzurum, S.C.5
-
31
-
-
45549098266
-
Induction of hypoxia-inducible factor lalpha gene expression by vascular endothelial growth factor. Role of a superoxide-mediated mechanism
-
Deudero, J. J., C. Caramelo, M. C. Castellanos, F. Neria, R. Fernandez-Sanchez, O. Calabia, S. Penate, and F. R. Gonzalez-Pacheco. 2008. Induction of hypoxia-inducible factor lalpha gene expression by vascular endothelial growth factor. Role of a superoxide-mediated mechanism. J. Biol. Chem. 283:11435-11444.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 11435-11444
-
-
Deudero, J.J.1
Caramelo, C.2
Castellanos, M.C.3
Neria, F.4
Fernandez-Sanchez, R.5
Calabia, O.6
Penate, S.7
Gonzalez-Pacheco, F.R.8
-
32
-
-
0028863701
-
Global cerebral ischemia in the rat: Online monitoring of oxygen free radical production using chemiluminescence in vivo
-
Dirnagl, U., U. Lindauer, A. Them, S. Schreiber, H. W. Pfister, U. Koedel, R. Reszka, D. Freyer, and A. Villringer. 1995. Global cerebral ischemia in the rat: online monitoring of oxygen free radical production using chemiluminescence in vivo. J. Cereb. Blood Flow Metab. 15:929-940.
-
(1995)
J. Cereb. Blood Flow Metab
, vol.15
, pp. 929-940
-
-
Dirnagl, U.1
Lindauer, U.2
Them, A.3
Schreiber, S.4
Pfister, H.W.5
Koedel, U.6
Reszka, R.7
Freyer, D.8
Villringer, A.9
-
33
-
-
0027970536
-
Role of hydrogen peroxide in hypoxia-induced erythropoietin production
-
Fandrey, J., S. Frede, and W. Jelkmann. 1994. Role of hydrogen peroxide in hypoxia-induced erythropoietin production. Biochem. J. 303:507-510.
-
(1994)
Biochem. J
, vol.303
, pp. 507-510
-
-
Fandrey, J.1
Frede, S.2
Jelkmann, W.3
-
34
-
-
4544346656
-
JunD reduces tumor angiogenesis by protecting cells from oxidative stress
-
Gerald, D., E. Berra, Y. M. Frapart, D. A. Chan, A. J. Giaccia, D. Mansuy, J. Pouyssegur, M. Yaniv, and F. Mechta-Grigoriou. 2004. JunD reduces tumor angiogenesis by protecting cells from oxidative stress. Cell 118:781-794.
-
(2004)
Cell
, vol.118
, pp. 781-794
-
-
Gerald, D.1
Berra, E.2
Frapart, Y.M.3
Chan, D.A.4
Giaccia, A.J.5
Mansuy, D.6
Pouyssegur, J.7
Yaniv, M.8
Mechta-Grigoriou, F.9
-
35
-
-
42449111722
-
PHDs overactivation during chronic hypoxia "desensitizes" HIFα and protects cells from necrosis
-
Ginouves, A., K. Ilc, N. Macias, J. Pouyssegur, and E. Berra. 2008. PHDs overactivation during chronic hypoxia "desensitizes" HIFα and protects cells from necrosis. Proc. Natl. Acad. Sci. USA 105:4745-4750.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 4745-4750
-
-
Ginouves, A.1
Ilc, K.2
Macias, N.3
Pouyssegur, J.4
Berra, E.5
-
36
-
-
34548148201
-
Hydrogen peroxide: A metabolic by-product or a common mediator of ageing signals?
-
Giorgio, M., M. Trinei, E. Migliaccio, and P. G. Pelicci. 2007. Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? Nat. Rev. Mol. Cell Biol. 8:722-728.
-
(2007)
Nat. Rev. Mol. Cell Biol
, vol.8
, pp. 722-728
-
-
Giorgio, M.1
Trinei, M.2
Migliaccio, E.3
Pelicci, P.G.4
-
37
-
-
0031025115
-
Homeostatic regulation of intracellular hydrogen peroxide concentration in aerobically growing Escherichia coli
-
Gonzalez-Flecha, B., and B. Demple. 1997. Homeostatic regulation of intracellular hydrogen peroxide concentration in aerobically growing Escherichia coli. J. Bacteriol. 179:382-388.
-
(1997)
J. Bacteriol
, vol.179
, pp. 382-388
-
-
Gonzalez-Flecha, B.1
Demple, B.2
-
38
-
-
28544446058
-
Mitochondrial tumour suppressors: A genetic and biochemical update
-
Gottlieb, E., and I. P. Tomlinson. 2005. Mitochondrial tumour suppressors: a genetic and biochemical update. Nat. Rev. Cancer 5:857-866.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 857-866
-
-
Gottlieb, E.1
Tomlinson, I.P.2
-
39
-
-
0023029160
-
Xanthine oxidase and neutrophil infiltration in intestinal ischemia
-
Grisham, M. B., L. A. Hernandez, and D. N. Granger. 1986. Xanthine oxidase and neutrophil infiltration in intestinal ischemia. Am. J. Physiol. 251:G567-G574.
-
(1986)
Am. J. Physiol
, vol.251
-
-
Grisham, M.B.1
Hernandez, L.A.2
Granger, D.N.3
-
40
-
-
24144493814
-
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
-
Guzy, R. D., B. Hoyos, E. Robin, H. Chen, L. Liu, K. D. Mansfield, M. C. Simon, U. Hammerling, and P. T. Schumacker. 2005. Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell. Metab. 1:401-408.
-
(2005)
Cell. Metab
, vol.1
, pp. 401-408
-
-
Guzy, R.D.1
Hoyos, B.2
Robin, E.3
Chen, H.4
Liu, L.5
Mansfield, K.D.6
Simon, M.C.7
Hammerling, U.8
Schumacker, P.T.9
-
41
-
-
33747596652
-
Oxygen sensing by mitochondria at complex III: The paradox of increased reactive oxygen species during hypoxia
-
Guzy, R. D., and P. T. Schumacker. 2006. Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Exp. Physiol. 91:807-819.
-
(2006)
Exp. Physiol
, vol.91
, pp. 807-819
-
-
Guzy, R.D.1
Schumacker, P.T.2
-
42
-
-
37849022071
-
Loss of the SdhB, but not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis
-
Guzy, R. D., B. Sharma, E. Bell, N. S. Chandel, and P. T. Schumacker. 2008. Loss of the SdhB, but not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis. Mol. Cell. Biol. 28:718-731.
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 718-731
-
-
Guzy, R.D.1
Sharma, B.2
Bell, E.3
Chandel, N.S.4
Schumacker, P.T.5
-
43
-
-
0035860375
-
A non-hypoxic, ROS-sensitive pathway mediates TNF-alpha-dependent regulation of HIF-1α
-
Haddad, J. J., and S. C. Land. 2001. A non-hypoxic, ROS-sensitive pathway mediates TNF-alpha-dependent regulation of HIF-1α. FEBS Lett. 505: 269-274.
-
(2001)
FEBS Lett
, vol.505
, pp. 269-274
-
-
Haddad, J.J.1
Land, S.C.2
-
44
-
-
0348134741
-
Redistribution of intracellular oxygen in hypoxia by nitric oxide: Effect on HIF1α
-
Hagen, T., C. T. Taylor, F. Lam, and S. Moncada. 2003. Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1α. Science 302:1975-1978.
-
(2003)
Science
, vol.302
, pp. 1975-1978
-
-
Hagen, T.1
Taylor, C.T.2
Lam, F.3
Moncada, S.4
-
45
-
-
0037474155
-
Structural biology. Complex II is complex too
-
Hederstedt, L. 2003. Structural biology. Complex II is complex too. Science 299:671-672.
-
(2003)
Science
, vol.299
, pp. 671-672
-
-
Hederstedt, L.1
-
46
-
-
39749113294
-
The interaction of superoxide with nitric oxide destabilizes hypoxia-inducible factor-1α
-
Herr, B., J. Zhou, S. Drose, and B. Brune. 2007. The interaction of superoxide with nitric oxide destabilizes hypoxia-inducible factor-1α. Cell Mol. Life Sci. 64:3295-3305.
-
(2007)
Cell Mol. Life Sci
, vol.64
, pp. 3295-3305
-
-
Herr, B.1
Zhou, J.2
Drose, S.3
Brune, B.4
-
47
-
-
38449113332
-
Hydrogen peroxide is a true first messenger
-
Holmquist, L., G. Stuchbury, M. Steele, and G. Munch. 2007. Hydrogen peroxide is a true first messenger. J. Neural Transm. Suppl. 2007:39-41.
-
(2007)
J. Neural Transm. Suppl
, vol.2007
, pp. 39-41
-
-
Holmquist, L.1
Stuchbury, G.2
Steele, M.3
Munch, G.4
-
48
-
-
0032514466
-
A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes
-
Ishii, N., M. Fujii, P. S. Hartman, M. Tsuda, K. Yasuda, N. Senoo-Matsuda, S. Yanase, D. Ayusawa, and K. Suzuki. 1998. A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes. Nature 394:694-697.
-
(1998)
Nature
, vol.394
, pp. 694-697
-
-
Ishii, N.1
Fujii, M.2
Hartman, P.S.3
Tsuda, M.4
Yasuda, K.5
Senoo-Matsuda, N.6
Yanase, S.7
Ayusawa, D.8
Suzuki, K.9
-
49
-
-
11244279161
-
A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis
-
Ishii, T., K. Yasuda, A. Akatsuka, O. Hino, P. S. Hartman, and N. Ishii. 2005. A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis. Cancer Res. 65:203-209.
-
(2005)
Cancer Res
, vol.65
, pp. 203-209
-
-
Ishii, T.1
Yasuda, K.2
Akatsuka, A.3
Hino, O.4
Hartman, P.S.5
Ishii, N.6
-
50
-
-
33747178432
-
Hypoxia in the tumorigenesis of gliomas and as a potential target for therapeutic measures
-
Jensen, R. L. 2006. Hypoxia in the tumorigenesis of gliomas and as a potential target for therapeutic measures. Neurosurg. Focus 20:E24.
-
(2006)
Neurosurg. Focus
, vol.20
-
-
Jensen, R.L.1
-
51
-
-
0036259903
-
Hypoxia-inducible factor-1α accumulation in the brain after experimental intracerebral hemorrhage
-
Jiang, Y., J. Wu, R. F. Keep, Y. Hua, J. T. Hoff, and G. Xi. 2002. Hypoxia-inducible factor-1α accumulation in the brain after experimental intracerebral hemorrhage. J. Cereb. Blood Flow Metab. 22:689-696.
-
(2002)
J. Cereb. Blood Flow Metab
, vol.22
, pp. 689-696
-
-
Jiang, Y.1
Wu, J.2
Keep, R.F.3
Hua, Y.4
Hoff, J.T.5
Xi, G.6
-
52
-
-
41849094797
-
Reactive oxygen species stabilize hypoxia inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells
-
Jung, S. N., W. K. Yang, J. Kim, H. S. Kim, E. J. Kim, H. Yun, H. Park, S. S. Kim, W. Choe, I. Kang, and J. Ha. 2008. Reactive oxygen species stabilize hypoxia inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells. Carcinogenesis 29:713-721.
-
(2008)
Carcinogenesis
, vol.29
, pp. 713-721
-
-
Jung, S.N.1
Yang, W.K.2
Kim, J.3
Kim, H.S.4
Kim, E.J.5
Yun, H.6
Park, H.7
Kim, S.S.8
Choe, W.9
Kang, I.10
Ha, J.11
-
53
-
-
33746930794
-
Succinate dehydrogenase and fumarate hydratase: Linking mitochondrial dysfunction and cancer
-
King, A., M. A. Selak, and E. Gottlieb. 2006. Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer. Oncogene 25:4675-4682.
-
(2006)
Oncogene
, vol.25
, pp. 4675-4682
-
-
King, A.1
Selak, M.A.2
Gottlieb, E.3
-
54
-
-
33646031246
-
Reactive oxygen species attenuate nitric-oxide-mediated hypoxia-inducible factor-1α stabilization
-
Kohl, R., J. Zhou, and B. Brune. 2006. Reactive oxygen species attenuate nitric-oxide-mediated hypoxia-inducible factor-1α stabilization. Free Radic. Biol. Med. 40:1430-1442.
-
(2006)
Free Radic. Biol. Med
, vol.40
, pp. 1430-1442
-
-
Kohl, R.1
Zhou, J.2
Brune, B.3
-
55
-
-
33947520506
-
Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: Possible links between cell metabolism and stabilization of HIF
-
Koivunen, P., M. Hirsila, A. M. Remes, I. E. Hassinen, K. I. Kivirikko, and J. Myllyharju. 2007. Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF. J. Biol. Chem. 282:4524-4532.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 4524-4532
-
-
Koivunen, P.1
Hirsila, M.2
Remes, A.M.3
Hassinen, I.E.4
Kivirikko, K.I.5
Myllyharju, J.6
-
56
-
-
33745006163
-
Nitric oxide inhibits HIF-1α protein accumulation under hypoxic conditions: Implication of 2-oxoglutarate and iron
-
Kozhukhar, A. V., I. M. Yasinska, and V. V. Sumbayev. 2006. Nitric oxide inhibits HIF-1α protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron. Biochimie 88:411-418.
-
(2006)
Biochimie
, vol.88
, pp. 411-418
-
-
Kozhukhar, A.V.1
Yasinska, I.M.2
Sumbayev, V.V.3
-
57
-
-
27744605175
-
Signal pathway of hypoxia-inducible factor-1α phosphorylation and its interaction with von Hippel-Lindau tumor suppressor protein during ischemia in MiaPaCa-2 pancreatic cancer cells
-
Kwon, S. J., J. J. Song, and Y. J. Lee. 2005. Signal pathway of hypoxia-inducible factor-1α phosphorylation and its interaction with von Hippel-Lindau tumor suppressor protein during ischemia in MiaPaCa-2 pancreatic cancer cells. Clin. Cancer Res. 11:7607-7613.
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 7607-7613
-
-
Kwon, S.J.1
Song, J.J.2
Lee, Y.J.3
-
58
-
-
0033695425
-
Plasma hydrogen peroxide production in human essential hypertension: Role of heredity, gender, and ethnicity
-
Lacy, F., M. T. Kailasam, D. T. O'Connor, G. W. Schmid-Schonbein, and R. J. Parmer. 2000. Plasma hydrogen peroxide production in human essential hypertension: role of heredity, gender, and ethnicity. Hypertension 36:878-884.
-
(2000)
Hypertension
, vol.36
, pp. 878-884
-
-
Lacy, F.1
Kailasam, M.T.2
O'Connor, D.T.3
Schmid-Schonbein, G.W.4
Parmer, R.J.5
-
59
-
-
20844447150
-
Controlling tumor growth by modulating endogenous production of reactive oxygen species
-
Laurent, A., C. Nicco, C. Chereau, C. Goulvestre, J. Alexandre, A. Alves, E. Levy, F. Goldwasser, Y. Panis, O. Soubrane, B. Weill, and F. Batteux. 2005. Controlling tumor growth by modulating endogenous production of reactive oxygen species. Cancer Res. 65:948-956.
-
(2005)
Cancer Res
, vol.65
, pp. 948-956
-
-
Laurent, A.1
Nicco, C.2
Chereau, C.3
Goulvestre, C.4
Alexandre, J.5
Alves, A.6
Levy, E.7
Goldwasser, F.8
Panis, Y.9
Soubrane, O.10
Weill, B.11
Batteux, F.12
-
60
-
-
34347230541
-
Docosahexaenoic acid supplementation induces dose and time dependent oxidative changes in C6 glioma cells
-
Leonardi, F., L. Attorri, R. D. Benedetto, A. D. Biase, M. Sanchez, F. P. Tregno, M. Nardini, and S. Salvati. 2007. Docosahexaenoic acid supplementation induces dose and time dependent oxidative changes in C6 glioma cells. Free Radic. Res. 41:748-756.
-
(2007)
Free Radic. Res
, vol.41
, pp. 748-756
-
-
Leonardi, F.1
Attorri, L.2
Benedetto, R.D.3
Biase, A.D.4
Sanchez, M.5
Tregno, F.P.6
Nardini, M.7
Salvati, S.8
-
61
-
-
34248396033
-
Dual role of hydrogen peroxide in cancer: Possible relevance to cancer chemoprevention and therapy
-
Lopez-Lazaro, M. 2007. Dual role of hydrogen peroxide in cancer: possible relevance to cancer chemoprevention and therapy. Cancer Lett. 252:1-8.
-
(2007)
Cancer Lett
, vol.252
, pp. 1-8
-
-
Lopez-Lazaro, M.1
-
62
-
-
17344377672
-
A kinetic study on iron stimulation of the xanthine oxidase dependent oxidation of ascorbate
-
Lovstad, R. A. 2003. A kinetic study on iron stimulation of the xanthine oxidase dependent oxidation of ascorbate. Biometals 16:435-439.
-
(2003)
Biometals
, vol.16
, pp. 435-439
-
-
Lovstad, R.A.1
-
63
-
-
29644442625
-
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1
-
Lu, H., C. L. Dalgard, A. Mohyeldin, T. McFate, A. S. Tait, and A. Verma. 2005. Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1. J. Biol. Chem. 280:41928-41939.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 41928-41939
-
-
Lu, H.1
Dalgard, C.L.2
Mohyeldin, A.3
McFate, T.4
Tait, A.S.5
Verma, A.6
-
64
-
-
34247553146
-
Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells
-
MacKenzie, E. D., M. A. Selak, D. A. Tennant, L. J. Payne, S. Crosby, C. M. Frederiksen, D. G. Watson, and E. Gottlieb. 2007. Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells. Mol. Cell. Biol. 27:3282-3289.
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 3282-3289
-
-
MacKenzie, E.D.1
Selak, M.A.2
Tennant, D.A.3
Payne, L.J.4
Crosby, S.5
Frederiksen, C.M.6
Watson, D.G.7
Gottlieb, E.8
-
66
-
-
24144447915
-
Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation
-
Mansfield, K. D., R. D. Guzy, Y. Pan, R. M. Young, T. P. Cash, P. T. Schumacker, and M. C. Simon. 2005. Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation. Cell. Metab. 1:393-399.
-
(2005)
Cell. Metab
, vol.1
, pp. 393-399
-
-
Mansfield, K.D.1
Guzy, R.D.2
Pan, Y.3
Young, R.M.4
Cash, T.P.5
Schumacker, P.T.6
Simon, M.C.7
-
67
-
-
33846869739
-
Age-related changes in mitochondrial function and antioxidative enzyme activity in Fischer 344 rats
-
Meng, Q., Y. T. Wong, J. Chen, and R. Ruan. 2007. Age-related changes in mitochondrial function and antioxidative enzyme activity in Fischer 344 rats. Mech. Ageing Dev. 128:286-292.
-
(2007)
Mech. Ageing Dev
, vol.128
, pp. 286-292
-
-
Meng, Q.1
Wong, Y.T.2
Chen, J.3
Ruan, R.4
-
68
-
-
2342611976
-
Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: Role of reoxygenation, free radicals, and stress granules
-
Moeller, B. J., Y. Cao, C. Y. Li, and M. W. Dewhirst. 2004. Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules. Cancer Cell 5:429-441.
-
(2004)
Cancer Cell
, vol.5
, pp. 429-441
-
-
Moeller, B.J.1
Cao, Y.2
Li, C.Y.3
Dewhirst, M.W.4
-
69
-
-
0037444052
-
Micromolar concentrations of hydrogen peroxide induce oxidative DNA lesions more efficiently than millimolar concentrations in mammalian cells
-
Nakamura, J., E. R. Purvis, and J. A. Swenberg. 2003. Micromolar concentrations of hydrogen peroxide induce oxidative DNA lesions more efficiently than millimolar concentrations in mammalian cells. Nucleic Acids Res. 31:1790-1795.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 1790-1795
-
-
Nakamura, J.1
Purvis, E.R.2
Swenberg, J.A.3
-
70
-
-
38749106115
-
Hypoxia-inducible factor-1α stabilization in nonhypoxic conditions: Role of oxidation and intracellular ascorbate depletion
-
Page, E. L., D. A. Chan, A. J. Giaccia, M. Levine, and D. E. Richard. 2008. Hypoxia-inducible factor-1α stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion. Mol. Biol. Cell 19:86-94.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 86-94
-
-
Page, E.L.1
Chan, D.A.2
Giaccia, A.J.3
Levine, M.4
Richard, D.E.5
-
71
-
-
33846630894
-
Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro
-
Pan, Y., K. D. Mansfield, C. C. Bertozzi, V. Rudenko, D. A. Chan, A. J. Giaccia, and M. C. Simon. 2007. Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro. Mol. Cell. Biol. 27:912-925.
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 912-925
-
-
Pan, Y.1
Mansfield, K.D.2
Bertozzi, C.C.3
Rudenko, V.4
Chan, D.A.5
Giaccia, A.J.6
Simon, M.C.7
-
72
-
-
21544465580
-
Substantial DNA damage from submicromolar intracellular hydrogen peroxide detected in Hpx- mutants of Escherichia coli
-
Park, S., X. You, and J. A. Imlay. 2005. Substantial DNA damage from submicromolar intracellular hydrogen peroxide detected in Hpx- mutants of Escherichia coli. Proc. Natl. Acad. Sci. USA 102:9317-9322.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9317-9322
-
-
Park, S.1
You, X.2
Imlay, J.A.3
-
73
-
-
0031942539
-
Increased formation of reactive oxygen species after permanent and reversible middle cerebral artery occlusion in the rat
-
Peters, O., T. Back, U. Lindauer, C. Busch, D. Megow, J. Dreier, and U. Dirnagl. 1998. Increased formation of reactive oxygen species after permanent and reversible middle cerebral artery occlusion in the rat. J. Cereb. Blood Flow Metab. 18:196-205.
-
(1998)
J. Cereb. Blood Flow Metab
, vol.18
, pp. 196-205
-
-
Peters, O.1
Back, T.2
Lindauer, U.3
Busch, C.4
Megow, D.5
Dreier, J.6
Dirnagl, U.7
-
74
-
-
26444570010
-
Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations
-
Pollard, P. J., J. J. Briere, N. A. Alam, J. Barwell, E. Barclay, N. C. Wortham, T. Hunt, M. Mitchell, S. Olpin, S. J. Moat, I. P. Hargreaves, S. J. Heales, Y. L. Chung, J. R. Griffiths, A. Dalgleish, J. A. McGrath, M. J. Gleeson, S. V. Hodgson, R. Poulsom, P. Rustin, and I. P. Tomlinson. 2005. Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations. Hum. Mol. Genet. 14:2231-2239.
-
(2005)
Hum. Mol. Genet
, vol.14
, pp. 2231-2239
-
-
Pollard, P.J.1
Briere, J.J.2
Alam, N.A.3
Barwell, J.4
Barclay, E.5
Wortham, N.C.6
Hunt, T.7
Mitchell, M.8
Olpin, S.9
Moat, S.J.10
Hargreaves, I.P.11
Heales, S.J.12
Chung, Y.L.13
Griffiths, J.R.14
Dalgleish, A.15
McGrath, J.A.16
Gleeson, M.J.17
Hodgson, S.V.18
Poulsom, R.19
Rustin, P.20
Tomlinson, I.P.21
more..
-
75
-
-
33750622643
-
Redox regulation of the hypoxia-inducible factor
-
Pouyssegur, J., and F. Mechta-Grigoriou. 2006. Redox regulation of the hypoxia-inducible factor. Biol. Chem. 387:1337-1346.
-
(2006)
Biol. Chem
, vol.387
, pp. 1337-1346
-
-
Pouyssegur, J.1
Mechta-Grigoriou, F.2
-
76
-
-
0037974523
-
Functional genomics and the comparative physiology of hypoxia
-
Powell, F. L. 2003. Functional genomics and the comparative physiology of hypoxia. Annu. Rev. Physiol. 65:203-230.
-
(2003)
Annu. Rev. Physiol
, vol.65
, pp. 203-230
-
-
Powell, F.L.1
-
77
-
-
33748774664
-
A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1 alpha
-
Qutub, A. A., and A. S. Popel. 2006. A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1 alpha. J. Cell Sci. 119: 3467-3480.
-
(2006)
J. Cell Sci
, vol.119
, pp. 3467-3480
-
-
Qutub, A.A.1
Popel, A.S.2
-
78
-
-
34848842419
-
Three autocrine feedback loops determine HIF1 alpha expression in chronic hypoxia
-
Qutub, A. A., and A. S. Popel. 2007. Three autocrine feedback loops determine HIF1 alpha expression in chronic hypoxia. Biochim. Biophys. Acta 1773:1511-1525.
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 1511-1525
-
-
Qutub, A.A.1
Popel, A.S.2
-
79
-
-
0017470593
-
Aeration without air: Oxygen supply by hydrogen peroxide
-
Schlegel, H. G. 1977. Aeration without air: oxygen supply by hydrogen peroxide. Biotechnol. Bioeng. 19:413-424.
-
(1977)
Biotechnol. Bioeng
, vol.19
, pp. 413-424
-
-
Schlegel, H.G.1
-
80
-
-
0023713873
-
Oxidant-induced DNA damage of target cells
-
Schraufstatter, I., P. A. Hyslop, J. H. Jackson, and C. G. Cochrane. 1988. Oxidant-induced DNA damage of target cells. J. Clin. Investig. 82:1040-1050.
-
(1988)
J. Clin. Investig
, vol.82
, pp. 1040-1050
-
-
Schraufstatter, I.1
Hyslop, P.A.2
Jackson, J.H.3
Cochrane, C.G.4
-
82
-
-
0035212036
-
Hydrogen peroxide fluxes and compartmentalization inside growing Escherichia coli
-
Seaver, L. C., and J. A. Imlay. 2001. Hydrogen peroxide fluxes and compartmentalization inside growing Escherichia coli. J. Bacteriol. 183:7182-7189.
-
(2001)
J. Bacteriol
, vol.183
, pp. 7182-7189
-
-
Seaver, L.C.1
Imlay, J.A.2
-
83
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
-
Selak, M. A., S. M. Armour, E. D. MacKenzie, H. Boulahbel, D. G. Watson, K. D. Mansfield, Y. Pan, M. C. Simon, C. B. Thompson, and E. Gottlieb. 2005. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell 7:77-85.
-
(2005)
Cancer Cell
, vol.7
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
MacKenzie, E.D.3
Boulahbel, H.4
Watson, D.G.5
Mansfield, K.D.6
Pan, Y.7
Simon, M.C.8
Thompson, C.B.9
Gottlieb, E.10
-
84
-
-
33745591371
-
Redox stress is not essential for the pseudo-hypoxic phenotype of succinate dehydrogenase deficient cells
-
Selak, M. A., R. V. Duran, and E. Gottlieb. 2006. Redox stress is not essential for the pseudo-hypoxic phenotype of succinate dehydrogenase deficient cells. Biochim. Biophys. Acta 1757:567-572.
-
(2006)
Biochim. Biophys. Acta
, vol.1757
, pp. 567-572
-
-
Selak, M.A.1
Duran, R.V.2
Gottlieb, E.3
-
85
-
-
8344237449
-
Hydroxylation of HIF-1: Oxygen sensing at the molecular level
-
Semenza, G. L. 2004. Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiology (Bethesda) 19:176-182.
-
(2004)
Physiology (Bethesda)
, vol.19
, pp. 176-182
-
-
Semenza, G.L.1
-
86
-
-
0035834789
-
A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans
-
Senoo-Matsuda, N., K. Yasuda, M. Tsuda, T. Ohkubo, S. Yoshimura, H. Nakazawa, P. S. Hartman, and N. Ishii. 2001. A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans. J. Biol. Chem. 276:41553-41558.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 41553-41558
-
-
Senoo-Matsuda, N.1
Yasuda, K.2
Tsuda, M.3
Ohkubo, T.4
Yoshimura, S.5
Nakazawa, H.6
Hartman, P.S.7
Ishii, N.8
-
87
-
-
0035933716
-
Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway
-
Srinivas, V., I. Leshchinsky, N. Sang, M. P. King, A. Minchenko, and J. Caro. 2001. Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway. J. Biol. Chem. 276:21995-21998.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 21995-21998
-
-
Srinivas, V.1
Leshchinsky, I.2
Sang, N.3
King, M.P.4
Minchenko, A.5
Caro, J.6
-
88
-
-
33646698671
-
Hydrogen peroxide: A signaling messenger
-
Stone, J. R., and S. Yang. 2006. Hydrogen peroxide: a signaling messenger. Antioxid. Redox Signal. 8:243-270.
-
(2006)
Antioxid. Redox Signal
, vol.8
, pp. 243-270
-
-
Stone, J.R.1
Yang, S.2
-
89
-
-
33744782345
-
Peroxynitrite as an alternative donor of oxygen in HIF-1α proline hydroxylation under low oxygen availability
-
Sumbayev, V. V., and I. M. Yasinska. 2006. Peroxynitrite as an alternative donor of oxygen in HIF-1α proline hydroxylation under low oxygen availability. Free Radic. Res. 40:631-635.
-
(2006)
Free Radic. Res
, vol.40
, pp. 631-635
-
-
Sumbayev, V.V.1
Yasinska, I.M.2
-
90
-
-
0026021362
-
Production of large amounts of hydrogen peroxide by human tumor cells
-
Szatrowski, T. P., and C. F. Nathan. 1991. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res. 51:794-798.
-
(1991)
Cancer Res
, vol.51
, pp. 794-798
-
-
Szatrowski, T.P.1
Nathan, C.F.2
-
91
-
-
34848866025
-
Ubiquinone-binding site mutations in the Saccharomyces cerevisiae succinate dehydrogenase generate superoxide and lead to the accumulation of succinate
-
Szeto, S. S., S. N. Reinke, B. D. Sykes, and B. D. Lemire. 2007. Ubiquinone-binding site mutations in the Saccharomyces cerevisiae succinate dehydrogenase generate superoxide and lead to the accumulation of succinate. J. Biol. Chem. 282:27518-27526.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 27518-27526
-
-
Szeto, S.S.1
Reinke, S.N.2
Sykes, B.D.3
Lemire, B.D.4
-
92
-
-
34447523351
-
Glutathione peroxidase, glutathione reductase and protein oxidation in patients with glioblastoma multiforme and transitional meningioma
-
Tanriverdi, T., H. Hanimoglu, T. Kacira, G. Z. Sanus, R. Kemerdere, P. Atukeren, K. Gumustas, B. Canbaz, and M. Y. Kaynar. 2007. Glutathione peroxidase, glutathione reductase and protein oxidation in patients with glioblastoma multiforme and transitional meningioma. J. Cancer Res. Clin. Oncol. 133:627-633.
-
(2007)
J. Cancer Res. Clin. Oncol
, vol.133
, pp. 627-633
-
-
Tanriverdi, T.1
Hanimoglu, H.2
Kacira, T.3
Sanus, G.Z.4
Kemerdere, R.5
Atukeren, P.6
Gumustas, K.7
Canbaz, B.8
Kaynar, M.Y.9
-
93
-
-
0032493381
-
Lower intracellular hydrogen peroxide levels in cells overexpressing CuZn-superoxide dismutase
-
Teixeira, H. D., R. I. Schumacher, and R. Meneghini. 1998. Lower intracellular hydrogen peroxide levels in cells overexpressing CuZn-superoxide dismutase. Proc. Natl. Acad. Sci. USA 95:7872-7875.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7872-7875
-
-
Teixeira, H.D.1
Schumacher, R.I.2
Meneghini, R.3
-
94
-
-
37549005208
-
Detection of reactive oxygen species via endogenous oxidative pentose phosphate cycle activity in response to oxygen concentration: Implications for the mechanism of HIF-1α stabilization under moderate hypoxia
-
Tuttle, S. W., A. Maity, P. R. Oprysko, A. V. Kachur, I. S. Ayene, J. E. Biaglow, and C. J. Koch. 2007. Detection of reactive oxygen species via endogenous oxidative pentose phosphate cycle activity in response to oxygen concentration: implications for the mechanism of HIF-1α stabilization under moderate hypoxia. J. Biol. Chem. 282:36790-36796.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 36790-36796
-
-
Tuttle, S.W.1
Maity, A.2
Oprysko, P.R.3
Kachur, A.V.4
Ayene, I.S.5
Biaglow, J.E.6
Koch, C.J.7
-
95
-
-
39749188133
-
The good, the bad, and the cell type-specific roles of hypoxia inducible factor-1 alpha in neurons and astrocytes
-
Vangeison, G., D. Carr, H. J. Federoff, and D. A. Rempe. 2008. The good, the bad, and the cell type-specific roles of hypoxia inducible factor-1 alpha in neurons and astrocytes. J. Neurosci. 28:1988-1993.
-
(2008)
J. Neurosci
, vol.28
, pp. 1988-1993
-
-
Vangeison, G.1
Carr, D.2
Federoff, H.J.3
Rempe, D.A.4
-
96
-
-
0035880239
-
Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain
-
Vaux, E. C., E. Metzen, K. M. Yeates, and P. J. Ratcliffe. 2001. Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain. Blood 98:296-302.
-
(2001)
Blood
, vol.98
, pp. 296-302
-
-
Vaux, E.C.1
Metzen, E.2
Yeates, K.M.3
Ratcliffe, P.J.4
-
97
-
-
0038724686
-
Evaluation of hypoxia-inducible factor-1α (HIF-1α) as an intrinsic marker of tumor hypoxia in U87 MG human glioblastoma: In vitro and xenograft studies
-
Vordermark, D., and J. M. Brown. 2003. Evaluation of hypoxia-inducible factor-1α (HIF-1α) as an intrinsic marker of tumor hypoxia in U87 MG human glioblastoma: in vitro and xenograft studies. Int. J. Radiat. Oncol. Biol. Phys. 56:1184-1193.
-
(2003)
Int. J. Radiat. Oncol. Biol. Phys
, vol.56
, pp. 1184-1193
-
-
Vordermark, D.1
Brown, J.M.2
-
99
-
-
0037365537
-
Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species
-
Wartenberg, M., F. C. Ling, M. Muschen, F. Klein, H. Acker, M. Gassmann, K. Petrat, V. Putz, J. Hescheler, and H. Sauer. 2003. Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species. FASEB J. 17:503-505.
-
(2003)
FASEB J
, vol.17
, pp. 503-505
-
-
Wartenberg, M.1
Ling, F.C.2
Muschen, M.3
Klein, F.4
Acker, H.5
Gassmann, M.6
Petrat, K.7
Putz, V.8
Hescheler, J.9
Sauer, H.10
-
100
-
-
1442339194
-
Nitric oxide and reactive oxygen species exert opposing effects on the stability of hypoxia-inducible factor-1α (HIF-1α) in explants of human pial arteries
-
Wellman, T. L., J. Jenkins, P. L. Penar, B. Tranmer, R. Zahr, and K. M. Lounsbury. 2004. Nitric oxide and reactive oxygen species exert opposing effects on the stability of hypoxia-inducible factor-1α (HIF-1α) in explants of human pial arteries. FASEB J. 18:379-381.
-
(2004)
FASEB J
, vol.18
, pp. 379-381
-
-
Wellman, T.L.1
Jenkins, J.2
Penar, P.L.3
Tranmer, B.4
Zahr, R.5
Lounsbury, K.M.6
-
101
-
-
84970583204
-
Outer-sphere electron transfer of ascorbate anions
-
Williams, N., and J. Yandell. 1982. Outer-sphere electron transfer of ascorbate anions. Aust. J. Chem. 35:1133-1144.
-
(1982)
Aust. J. Chem
, vol.35
, pp. 1133-1144
-
-
Williams, N.1
Yandell, J.2
-
102
-
-
36348938884
-
Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor
-
Xia, C., Q. Meng, L. Z. Liu, Y. Rojanasakul, X. R. Wang, and B. H. Jiang. 2007. Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor. Cancer Res. 67:10823-10830.
-
(2007)
Cancer Res
, vol.67
, pp. 10823-10830
-
-
Xia, C.1
Meng, Q.2
Liu, L.Z.3
Rojanasakul, Y.4
Wang, X.R.5
Jiang, B.H.6
-
103
-
-
0037947590
-
Redox regulation of HIF-1alpha levels and HO-1 expression in renal medullary interstitial cells
-
Yang, Z. Z., A. Y. Zhang, F. X. Yi, P. L. Li, and A. P. Zou. 2003. Redox regulation of HIF-1alpha levels and HO-1 expression in renal medullary interstitial cells. Am. J. Physiol. Renal Physiol. 284:F1207-F1215.
-
(2003)
Am. J. Physiol. Renal Physiol
, vol.284
-
-
Yang, Z.Z.1
Zhang, A.Y.2
Yi, F.X.3
Li, P.L.4
Zou, A.P.5
-
104
-
-
0348150715
-
Architecture of succinate dehydrogenase and reactive oxygen species generation
-
Yankovskaya, V., R. Horsefield, S. Tornroth, C. Luna-Chavez, H. Miyoshi, C. Leger, B. Byrne, G. Cecchini, and S. Iwata. 2003. Architecture of succinate dehydrogenase and reactive oxygen species generation. Science 299: 700-704.
-
(2003)
Science
, vol.299
, pp. 700-704
-
-
Yankovskaya, V.1
Horsefield, R.2
Tornroth, S.3
Luna-Chavez, C.4
Miyoshi, H.5
Leger, C.6
Byrne, B.7
Cecchini, G.8
Iwata, S.9
-
105
-
-
0033460221
-
Expression of superoxide dismutases, catalase, and glutathione peroxidase in glioma cells
-
Zhong, W., T. Yan, R. Lim, and L. W. Oberley. 1999. Expression of superoxide dismutases, catalase, and glutathione peroxidase in glioma cells. Free Radic. Biol. Med. 27:1334-1345.
-
(1999)
Free Radic. Biol. Med
, vol.27
, pp. 1334-1345
-
-
Zhong, W.1
Yan, T.2
Lim, R.3
Oberley, L.W.4
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