Increased formation of reactive oxygen species after permanent and reversible middle cerebral artery occlusion in the rat

Journal of Cerebral Blood Flow and Metabolism

Volumn 18, Issue 2, 1998, Pages 196-205

  Peters, Oliver ^c   Back, Tobias ^a,b   Lindauer, Ute ^c   Busch, Christina ^c   Megow, Dirk ^c   Dreier, Jens ^c   Dirnagl, Ulrich ^c  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c NONE

Author keywords

Cranial window; DC potential; Focal ischemia; Reactive oxygen species; Superoxide radicals

Indexed keywords

REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN EDEMA; BRAIN INFARCTION; CONTROLLED STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

EID: 0031942539     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199802000-00011     Document Type: Article

References (50)

1. Abe K, Yuki S, Kogure K (1988) Strong attenuation of ischemic and postischemic brain edema in rats by a novel free radical scavenger. Stroke 19:480-485
2. Archer SL, Nelson DP, Weir EK (1989) Detection of activated O2 species in vitro and in rat lungs by chemiluminescence. J Appl Physiol 67:1912-1921
3. Back T, Hoehn-Berlage M, Kohno K, Hossmann K-A (1994a) Diffusion nuclear magnetic resonance imaging in experimental stroke. Stroke 25:494-500
4. Back T, Kohno K, Hossmann K-A (1994b) Conical negative DC deflections following middle cerebral artery occlusion and KCl-induced spreading depression: effect on blood flow, tissue oxygenation and electroencephalogram. J Cereb Blood Flow Metab 14: 12-19
5. Back T, Zhao W, Ginsberg MD (1995) Three-dimensional image analysis of brain glucose metabolism-blood flow uncoupling and its electrophysiological correlates in the acute ischemic penumbra following middle cerebral artery occlusion. J Cereb Blood Flow Metab 15:566-577
6. Back T, Ginsberg MD, Dietrich WD, Watson BD (1996) Induction of spreading depression in the ischemic hemisphere following experimental middle cerebral artery occlusion: effect on infarct morphology. J Cereb Blood Flow Metab 16:202-213
7. Back T, Nedergaard M, Ginsberg MD (1997) The ischemic penumbra: pathophysiology, and relevance of spreading depression-like phenomena. In: Cerebrovascular Disease - Pathophysiology, Diagnosis, and Treatment (Ginsberg MD, Bogousslavsky J, eds) Cambridge, MA, Blackwell Scientific (in press)
8. Boveris A, Chance B (1973) The mitochondrial generation of hydrogen peroxide. Biochem J 134:707-716
9. Braughler JM, Hall ED (1989) Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation. Free Rad Biol Med 6:289-301
10. Caggiano AO, Kraig RP (1997) Expression pattern of superoxide dismutase expression following neocortical spreading depression. J Cereb Blood Flow Metab 17 (Suppl 1):S553
11. Chan PH (1996) Role of oxidants in ischemic brain damage. Stroke 27:1124-1129
12. Dietrich WD, Nakayama H, Watson BD, Kanemitsu H (1989) Morphological consequences of early reperfusion following thrombotic or mechanical occlusion of the rat middle cerebral artery. Acta Neuropathol 78:605-614
13. Dietrich WD (1994) Morphological manifestations of reperfusion injury in brain. Ann N Y Acad Sci 723:15-24
14. Dirnagl U, Kaplan B, Jacewicz M, Pulsinelli W (1989) Continuous measurement of cerebral cortical blood flow by laser-Doppler flowmetry in a rat stroke model. J Cereb Blood Flow Metab 9: 589-596
15. Dirnagl U, Lindauer U, Schreiber S, Pfister HW, Koedel U, Reszka R, Freyer D, Villringer A (1995) Global cerebral ischemia in the rat: online monitoring of oxygen free radical production using chemiluminescence in vivo. J Cereb Blood Flow Metab 15:929-940
16. Ginsberg MD, Globus MYT, Martinez E, Morimoto T, Lin B, Schnippering H, Busto R (1994) Oxygen radical and excitotoxic processes in brain ischemia and trauma. In: Pharmacology of Cerebral Ischemia (Kriegelstein J, Oberpichler-Schwenk J, eds) Stuttgart, Wissenschaftliche Verlagsgesellschaft, pp 255-268
17. 1H-MRS. Magn Reson Med 31:337-341
18. He YY, Hsu CY, Ezrin AM, Miller MS (1993) Polyethylene glycol-conjugated superoxide dismutase in focal cerebral ischemia-reperfusion. Am J Physiol 265:H252-H256
19. Hossmann K-A (1997) Periinfarct depolarizations (Review). Cerebrovasc Brain Metab Rev 8:195-208
20. Hossmann KA, Mies G, Paschen W, Csiba L, Bodsch W, Rapin JR, Le Poncin-Lafitte MT (1985) Multiparametric imaging of blood flow and metabolism after middle cerebral artery occlusion in cats. J Cereb Blood Flow Metab 5:97-107
21. Iadecola C, Zhang F, Xu X (1995) Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage. Am J Physiol 37:R286-R292
22. Ikeda Y, Long DM (1990) The molecular basis of brain injury and brain edema: the role of oxygen free radicals. J Neurosurgery 27:1-11
23. Imaizumi S, Woolworth V, Fishman RA, Chan PH (1990) Liposome-entrapped superoxide dismutase reduces cerebral infarction in cerebral ischemia in rats. Stroke 21:1312-1317
24. Kinouchi H, Epstein CJ, Mizui T, Carlson E, Chen SF, Chan PH (1991) Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase. Proc Natl Acad Sci USA 88:11158-11162
25. Kochanek PM, Hallenbeck JM (1992) Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke. Stroke 23:1367-1379
26. Kogure K, Busto R, Schwarzman RJ, Scheinberg P (1980) The dissociation of cerebral blood flow, metabolism, and function in the early stages of developing cerebral infarction. Ann Neurol 8:278-290
27. Kohno K, Back T, Hoehn-Berlage M, Hossmann K-A (1995) A modified rat model of middle cerebral artery thread occlusion under electrophysiological control for magnetic resonance investigations. Magn Reson Imag 13:65-71
28. Korematsu K, Goto S, Nagahiro S, Ushio Y (1994) Microglial response to transient focal cerebral ischemia: an immunocytochemical study on the rat cerebral cortex using anti-phosphotyrosine antibody. J Cereb Blood Flow Metab 14:825-830
29. Lindauer U, Villringer A, Dirnagl U (1993) Characterization of CBF response to somatosensory stimulation: model and influence of anesthetics. Am J Physiol 264:H1223-H1228
30. Liu TH, Beckman JS, Freeman BA, Hogan EL, Hsu CY (1989) Polyethylene glycol conjugated superoxide dismutase and catalase reduce ischemic brain injury. Am J Physiol 256:H589-H593
31. Longa EZ, Weinstein PR, Carlson S, Cummins R (1989) Reversible middle artery occlusion without craniectomy in rats. Stroke 20:84-91
32. Matsushima K, Hogan MJ, Hakim AM (1996) Cortical spreading depression protects against subsequent focal cerebral ischemia in rats. J Cereb Blood Flow Metab 16:221-226
33. Matsuo Y, Kihara T, Ikeda M, Ninomiya M, Onodera H, Kogure K (1995) Role of neutrophils in radical production during ischemia and reperfusion of the rat brain: effect of neutrophil depletion on extracellular ascorbyl radical formation. J Cereb Blood Flow Metab 15:941-947
34. Mies G, Iijima T, Hossmann K-A (1993) Correlation between peri-infarct DC shifts and ischemic neuronal damage in cerebral cortex of the rat. Neuroreport 4:709-711
35. Morimoto T, Globus MYT, Busto R, Martinez E, Ginsberg MD (1996) Simultaneous measurement of salicylate hydroxylation and glutamate release in the penumbral cortex following transient middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab 16: 92-99
36. Nagasawa H, Kogure K (1989) Correlation between cerebral blood flow and histologic changes in a new rat model of middle cerebral artery occlusion. Stroke 20:1037-1043
37. Nedergaard M, Astrup J (1986) Infarct rim: effect of hyperglycemia on direct current potential and [14C]2-deoxyglucose phosphorylation. J Cereb Blood Flow Metab 6:607-615
38. Nedergaard M, Hansen AJ (1993) Characterization of cortical depolarizations evoked in focal cerebral ischemia. J Cereb Blood Flow Metab 13:568-574
39. Nowak TS Jr, Jacewicz M (1994) The heat shock/stress response in focal cerebral ischemia. Brain Pathol 4:67-76
40. Oh SM, Betz AL (1991) Interaction between free radicals and excitatory amino acids in the formation of ischemic brain edema in rats. Stroke 22:915-921
41. Paky A, Michael JR, Burke Wolin TM, Wolin MS, Gurtner GH (1993) Endogenous production of superoxide by rabbit lungs: effects of hypoxia or metabolic inhibitors. J Appl Physiol 74:2868-2874
42. Pellegrini-Giampietro DE, Cherici G, Alesiana M, Carla V, Moroni F (1990) Excitatory amino acid release and free radical formation may cooperate in the genenesis of ischemia-induced neuronal damage. J Neurosci 10:1035-1041
43. Siesjö BK, Zhao Q, Pahlmark K, Siesjö P, Katsura K, Folbergrova J (1995) Glutamate, calcium, and free radicals as mediators of ischemic brain damage. Ann Thorac Surg 59:1316-1320
44. Takeda Y, Jacewicz M, Nowak TS, Pulsinelli W (1993) DC-potential and energy metabolites in the focal ischemia. J Cereb Blood Flow Metab 13 (Suppl 1):S450
45. Traystman RJ, Kirsch JR, Koehler RC (1991) Oxygen radical mechanisms of brain injury following ischemia and reperfusion. J Appl Physiol 71:1185-1195
46. Tyson GW, Teasdale GM, Graham DI, McCulloch (1984) Focal cerebral ischemia in the rat: topography of nemodynamic and histopathological changes. Ann Neurol 15:559-567
47. Victorov IV, Barskow IV (1993) A method for staining ischemic neurons in the brain and spinal cord. Pathol Physiol Exp Therap 2:53
48. Watanabe T, Yuki S, Egawa M, Nishi H (1994) Protective effects of MCI-186 on cerebral ischemia: possible involvement of free radical scavenging and antioxidant actions. J Pharmacol Exp Ther 268:1597-1604
49. Yang G, Chan PH, Chen J, Carlson E, Chen SF, Weinstein PR, Epstein CJ, Kamii H (1994) Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia. Stroke 25:165-170
50. Yusa T, Crapo JD, Freeman BA (1984) Liposome-mediated augmentation of brain SOD and catalase inhibits CNS O2 toxicity. J Appl Physiol 57:1674-1681