Effects of modulators of the production and degradation of hydrogen peroxide on erythropoietin synthesis

Respiration Physiology

Volumn 114, Issue 2, 1998, Pages 175-183

  Canbolat, O ^a   Fandrey, J ^a   Jelkmann, W ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Chemicals, reactive O2 species; Enzymes, erythropoietin; Hypoxia, erythropoietin; Mammals, humans; Oxygen, sensing, H2O2

Indexed keywords

ANTIOXIDANT; CATALASE; ERYTHROPOIETIN; GLUCOSE OXIDASE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RHODAMINE; SUPEROXIDE DISMUTASE; THIOUREA DERIVATIVE; XANTHINE OXIDASE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPOXIA; LIVER CELL CULTURE; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ANOXIA; CARCINOMA, HEPATOCELLULAR; CATALASE; ERYTHROPOIETIN; FREE RADICAL SCAVENGERS; GLUTATHIONE PEROXIDASE; HUMANS; HYDROGEN PEROXIDE; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TUMOR CELLS, CULTURED;

EID: 0031791118     PISSN: 00345687     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0034-5687(98)00080-2     Document Type: Article

References (35)

1. Acker H. Mechanisms and meaning of cellular oxygen sensing in the organism. Respir. Physiol. 95:1994;1-10.
2. Aebi H. Catalase. Bergmeyer H.U. Methods of Enzymatic Analysis. 1974;673-683 Academic Press, New York.
3. 2 sensor in the pulmonary artery. J. Appl. Physiol. 66:1989;167-170.
4. Czyzyk-Krzeska M.F. Molecular aspects of oxygen sensing in physiological adaptation to hypoxia. Respir. Physiol. 110:1997;99-111.
5. Cool R.H., Merten E., Theiss C., Acker H. Rac1, and not Rac2, is involved in the regulation of the intracellular hydrogen peroxide level in HepG2 cells. Biochem. J. 332:1998;5-8.
6. Durak I., Isik A.C.Ü., Canbolat O., Akyol O., Kavutcu M. Adenosine deaminase, 5′ nucleotidase, xanthine oxidase, superoxide dismutase, and catalase activities in cancerous and noncancerous human laryngeal tissues. Free Rad. Biol. Med. 15:1993;681-684.
7. Durak I., Canbolat O., Kavutcu M., Öztürk H.S., Yurtarsl Z. Activities of total, cytoplasmic, and mitochondrial superoxide-dismutase enzymes in sera and pleural fluids from patients with lung-cancer. J. Clin. Lab. Anal. 10:1996;17-20.
8. Durak I., Güven T., Birey M., Öztürk H.S., Kurtipek Ö., Yel M., Dikmen B., Canbolat O. Halothane hepatotoxicity and hepatic free radical metabolism in guinea pigs; the effects of vitamin E. Can. J. Anaesth. 43:1996;741-748.
9. Ehleben W., Porwol T., Fandrey J., Kummer W., Acker H. Cobalt and desferrioxamine reveal crucial members of the oxygen sensing pathway in HepG2 cells. Kidney Int. 51:1997;483-491.
10. 450 in the control of the production of erythropoietin. Life Sci. 47:1990;127-134.
11. Fandrey J., Frede S., Jelkmann W. Role of hydrogen peroxide in hypoxia-induced erythropoietin production. Biochem. J. 303:1994;507-510.
12. Fandrey J., Frede S., Ehleben W., Porwol T., Acker H., Jelkmann W. Cobalt chloride and desferrioxamine antagonize the inhibition of erythropoietin production by reactive oxygen species. Kidney Int. 51:1997;492-496.
13. Gleadle J.M., Ebert B.L., Firth J.D., Ratcliffe P.J. Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents. Am. J. Physiol. 268:1995;C1362-C1368.
14. Goldberg M.A., Glass G.A., Cunningham J.M., Bunn H.F. The regulated expression of erythropoietin by two human hepatoma cell lines. Proc. Natl. Acad. Sci. USA. 84:1987;7972-7976.
15. Görlach A., Holtermann G., Jelkmann W., Hancock J.T., Jones S.A., Jones O.T.G., Acker H. Photometric characteristics of haem proteins in erythropoietin-producing hepatoma cells (HepG2). Biochem. J. 290:1993;771-776.
16. Huang L.E., Arany Z., Livingston D.M., Bunn H.F. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α-subunit. J. Biol. Chem. 271:1996;32253-32259.
17. Imagawa S., Yamamoto M., Ueda M., Miura Y. Erythropoietin gene expression by hydrogen peroxide. Int. J. Hematol. 64:1996;189-195.
18. Kavutcu M., Canbolat O., Öztürk H.S., Olcay E., Ulutepe S., Ekinci C., Gökhun I.H., Durak I. Reduced enzymatic antioxidant defense mechanism in kidney tissues from gentamicin-treated guinea pigs: effects of vitamins E and C. Nephron. 72:1996;269-274.
19. 2. Biochem. J. 321:1997;17-20.
20. 2+ signaling followed by phospholipase-A2 activation and potentiated by an adenosine derivative. Endocrinology. 136:1995;116-123.
21. Kling P.J., Dragsten P.R., Roberts R.A., Santos B.D., Brooks D.J., Hedlund B.E., Taetle R. Iron deprivation increases erythropoietin production in vitro, in normal subjects and patients with malignancy. Br. J. Haematol. 95:1996;241-248.
22. 2 sensors in hypoxic regulation of tyrosine hydroxylase gene expression. Am. J. Physiol. 274:1998;C167-C174.
23. Lander H.M. An essential role for free radicals and derived species in signal transduction. FASEB J. 11:1997;118-124.
24. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
25. 2 consumption in monolayer cell cultures. Respir. Physiol. 100:1994;101-106.
26. Paglia D.E., Valentine W. N. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 70:1967;158-169.
27. Röhrdanz E., Kahl R. Alterations of antioxidant enzyme expression in response to hydrogen peroxide. Free Rad. Biol. Med. 24:1998;27-38.
28. Salceda S., Caro J. Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. J. Biol. Chem. 272:1997;22642-22647.
29. Sato K., Ito K., Kohara H., Yamaguchi Y., Adachi K., Endo H. Negative regulation of catalase gene expression in hepatoma cells. Mol. Cell Biol. 12:1992;2525-2533.
30. Satriano J.A., Shuldiner M., Hora K., Xing Y., Shan Z., Schlondorff D. Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1, and the monocyte colony-stimulating factor, CSF-1, in response to tumor necrosis factor-β and immunoglobulin G. J. Clin. Invest. 92:1993;1564-1571.
31. Spagnoli A., Spadoni G.L., Sesti G., Del-Principe D., Germani D., Boscherini B. Effect of insulin on hydrogen peroxide production by human polymorphonuclear leukocytes. Studies with monoclonal anti-insulin receptor antibodies, and an agonist and an inhibitor of protein kinase C. Horm. Res. 43:1995;286-293.
32. Wang G.L., Jiang B.-H., Semenza G.L. Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1. Biochem. Biophys. Res. Commun. 212:1995;550-556.
33. 558 containing nicotinamide adenine dinucleotide phosphate oxidase. Blood. 87:1996;756-761.
34. Wolff M., Jelkmann W. Effects of chemotherapeutic and immunosuppressive drugs on the production of erythropoietin in human hepatoma cultures. Ann. Hematol. 66:1993;27-31.
35. O2 in erythropoietin-producing human hepatoma cell cultures. Am. J. Physiol. 265, C1266-C1270.