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Volumn 64, Issue 24, 2007, Pages 3295-3305

The interaction of superoxide with nitric oxide destabilizes hypoxia-inducible factor-1α

Author keywords

Calcium; Calpain; HIF 1 ; Mitochondria; Nitric oxide; Oxygen radicals

Indexed keywords

CALPAIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NITRIC OXIDE; SUPEROXIDE;

EID: 39749113294     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-007-7371-9     Document Type: Article
Times cited : (12)

References (51)
  • 1
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
    • Semenza, G. L. and Wang, G. L. (1992) A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol. Cell Biol. 12, 5447-5454.
    • (1992) Mol. Cell Biol , vol.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 2
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Wang, G. L. and Semenza, G. L. (1995) Purification and characterization of hypoxia-inducible factor 1. J. Biol. Chem. 270, 1230-1237.
    • (1995) J. Biol. Chem , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 3
    • 0037098081 scopus 로고    scopus 로고
    • How oxygen makes its presence felt
    • Kaelin, Jr. W. G. (2002) How oxygen makes its presence felt. Genes Dev. 16, 1441-1445.
    • (2002) Genes Dev , vol.16 , pp. 1441-1445
    • Kaelin Jr., W.G.1
  • 4
    • 0242330181 scopus 로고    scopus 로고
    • Oxygen sensing in the hypoxic response pathway: Regulation of the hypoxia-inducible transcription factor
    • Bruick, R. K. (2003) Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor. Genes Dev. 17, 2614-2623.
    • (2003) Genes Dev , vol.17 , pp. 2614-2623
    • Bruick, R.K.1
  • 5
    • 0037490210 scopus 로고    scopus 로고
    • Hypoxia-inducible factor and its biomedical relevance
    • Huang, L. E. and Bunn, H. F. (2003) Hypoxia-inducible factor and its biomedical relevance. J. Biol. Chem. 278, 19575-19578.
    • (2003) J. Biol. Chem , vol.278 , pp. 19575-19578
    • Huang, L.E.1    Bunn, H.F.2
  • 6
    • 0038037735 scopus 로고    scopus 로고
    • Regulation of angiogenesis by hypoxia: Role of the HIF system
    • Pugh, C.W. and Ratcliffe, P. J. (2003) Regulation of angiogenesis by hypoxia: role of the HIF system. Nat. Med. 9, 677-684.
    • (2003) Nat. Med , vol.9 , pp. 677-684
    • Pugh, C.W.1    Ratcliffe, P.J.2
  • 7
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza, G. L. (2003)Targeting HIF-1 for cancer therapy.Nat. Rev. Cancer 3, 721-732.
    • (2003) Nat Rev. Cancer , vol.3 , pp. 721-732
    • Semenzag, L.1
  • 8
    • 0035887011 scopus 로고    scopus 로고
    • FIH-1: A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity
    • Mahon, P. C., Hirota, K. and Semenza, G. L. (2001) FIH-1: A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev. 15, 2675-2686.
    • (2001) Genes Dev , vol.15 , pp. 2675-2686
    • Mahon, P.C.1    Hirota, K.2    Semenza, G.L.3
  • 11
    • 0035880239 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain
    • Vaux, E. C., Metzen, E., Yeates, K. M. and Ratcliffe, P. J. (2001) Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain. Blood 98, 296-302.
    • (2001) Blood , vol.98 , pp. 296-302
    • Vaux, E.C.1    Metzen, E.2    Yeates, K.M.3    Ratcliffe, P.J.4
  • 13
    • 24144447915 scopus 로고    scopus 로고
    • Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation
    • Mansfield, K. D., Guzy, R. D., Pan, Y., Young, R. M., Cash, T. P., Schumacker, P. T. and Simon, M. C. (2005) Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation. Cell Metab. 1, 393-399.
    • (2005) Cell Metab , vol.1 , pp. 393-399
    • Mansfield, K.D.1    Guzy, R.D.2    Pan, Y.3    Young, R.M.4    Cash, T.P.5    Schumacker, P.T.6    Simon, M.C.7
  • 15
    • 33645748498 scopus 로고    scopus 로고
    • Regulation of cardiotrophin-1 expression in mouse embryonic stem cells by HIF-1alpha and intracellular reactive oxygen species
    • Ateghang, B., Wartenberg, M., Gassmann, M. and Sauer, H. (2006) Regulation of cardiotrophin-1 expression in mouse embryonic stem cells by HIF-1alpha and intracellular reactive oxygen species. J. Cell Sci. 119, 1043-1052.
    • (2006) J. Cell Sci , vol.119 , pp. 1043-1052
    • Ateghang, B.1    Wartenberg, M.2    Gassmann, M.3    Sauer, H.4
  • 16
    • 0037073695 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms
    • Page, E. L., Robitaille, G. A., Pouyssegur, J. and Richard, D. E. (2002) Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms. J. Biol. Chem. 277, 48403-48409.
    • (2002) J. Biol. Chem , vol.277 , pp. 48403-48409
    • Pagee, L.1    Robitailleg, A.2    Pouyssegur, J.3    Richardd, E.4
  • 17
    • 0037165643 scopus 로고    scopus 로고
    • Crystal structure of a clavaminate synthase-Fe(II)-2-oxoglutarate- substrate-NO complex: Evidence for metal centered rearrangements
    • Zhang, Z., Ren, J., Harlos, K., McKinnon, C. H., Clifton, I. J. and Schofield, C. J. (2002) Crystal structure of a clavaminate synthase-Fe(II)-2- oxoglutarate-substrate-NO complex: Evidence for metal centered rearrangements. FEBS Lett. 517, 7-12.
    • (2002) FEBS Lett , vol.517 , pp. 7-12
    • Zhang, Z.1    Ren, J.2    Harlos, K.3    McKinnon, C.H.4    Clifton, I.J.5    Schofield, C.J.6
  • 18
    • 0042469448 scopus 로고    scopus 로고
    • Nitric oxide impairs normoxic degradation of HIF- 1alpha by inhibition of prolyl hydroxylases
    • Metzen, E., Zhou, J., Jelkmann, W., Fandrey, J. and Brune, B. (2003) Nitric oxide impairs normoxic degradation of HIF- 1alpha by inhibition of prolyl hydroxylases. Mol. Biol. Cell 14, 3470-3481.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 3470-3481
    • Metzen, E.1    Zhou, J.2    Jelkmann, W.3    Fandrey, J.4    Brune, B.5
  • 20
    • 33646031246 scopus 로고    scopus 로고
    • Reactive oxygen species attenuate nitric-oxide-mediated hypoxia-inducible factor- 1alpha stabilization
    • Kohl, R., Zhou, J. and Brune, B. (2006) Reactive oxygen species attenuate nitric-oxide-mediated hypoxia-inducible factor- 1alpha stabilization. Free Radic. Biol. Med. 40, 1430-1442.
    • (2006) Free Radic. Biol. Med , vol.40 , pp. 1430-1442
    • Kohl, R.1    Zhou, J.2    Brune, B.3
  • 22
    • 0032511014 scopus 로고    scopus 로고
    • Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5' enhancer
    • Liu, Y., Christou, H., Morita, T., Laughner, E., Semenza, G. L. andKourembanas, S. (1998) Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5' enhancer. J. Biol. Chem. 273, 15257-15262.
    • (1998) J. Biol. Chem , vol.273 , pp. 15257-15262
    • Liu, Y.1    Christou, H.2    Morita, T.3    Laughner, E.4    Semenza, G.L.5    Kourembanas, S.6
  • 25
    • 1442339194 scopus 로고    scopus 로고
    • Nitric oxide and reactive oxygen species exert opposing effects on the stability of hypoxiainducible factor-1alpha (HIF-1alpha) in explants of human pial arteries
    • Wellman, T. L., Jenkins, J., Penar, P. L., Tranmer, B., Zahr, R. and Lounsbury, K. M. (2004) Nitric oxide and reactive oxygen species exert opposing effects on the stability of hypoxiainducible factor-1alpha (HIF-1alpha) in explants of human pial arteries. FASEB J. 18, 379-381.
    • (2004) FASEB J , vol.18 , pp. 379-381
    • Wellman, T.L.1    Jenkins, J.2    Penar, P.L.3    Tranmer, B.4    Zahr, R.5    Lounsbury, K.M.6
  • 27
    • 1642556829 scopus 로고    scopus 로고
    • Protein kinase C zeta transactivates hypoxia-inducible factor alpha by promoting its association with p300 in renal cancer
    • Datta, K., Li, J., Bhattacharya, R., Gasparian, L., Wang, E. and Mukhopadhyay, D. (2004) Protein kinase C zeta transactivates hypoxia-inducible factor alpha by promoting its association with p300 in renal cancer. Cancer Res. 64, 456-462.
    • (2004) Cancer Res , vol.64 , pp. 456-462
    • Datta, K.1    Li, J.2    Bhattacharya, R.3    Gasparian, L.4    Wang, E.5    Mukhopadhyay, D.6
  • 28
    • 35148860529 scopus 로고    scopus 로고
    • PKC-mediated modulation of factor inhibiting HIF-1 (FIH-1) expression by the homeodomain protein CDP/Cut/Cux
    • Li, J., Wang, E., Dutta, S., Lau, J. S., Jiang, S.W., Datta, K. and Mukhopadhyay, D. (2007) PKC-mediated modulation of factor inhibiting HIF-1 (FIH-1) expression by the homeodomain protein CDP/Cut/Cux. Mol. Cell Biol. 20, 7345-7353.
    • (2007) Mol. Cell Biol , vol.20 , pp. 7345-7353
    • Li, J.1    Wang, E.2    Dutta, S.3    Lau, J.S.4    Jiang, S.W.5    Datta, K.6    Mukhopadhyay, D.7
  • 29
    • 33745398366 scopus 로고    scopus 로고
    • Calpain mediates a von Hippel-Lindau protein-independent destruction of hypoxia-inducible factor-1alpha
    • Zhou, J., Kohl, R., Herr, B., Frank, R. and Brune, B. (2006) Calpain mediates a von Hippel-Lindau protein-independent destruction of hypoxia-inducible factor-1alpha. Mol. Biol. Cell 17, 1549-1558.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 1549-1558
    • Zhou, J.1    Kohl, R.2    Herr, B.3    Frank, R.4    Brune, B.5
  • 30
    • 0036566855 scopus 로고    scopus 로고
    • Modulation of mitochondrial transcription in response to mtDNA depletion and repletion in HeLa cells
    • Seidel-Rogol, B. L. and Shadel, G. S. (2002) Modulation of mitochondrial transcription in response to mtDNA depletion and repletion in HeLa cells. Nucleic Acids Res. 30, 1929-1934.
    • (2002) Nucleic Acids Res , vol.30 , pp. 1929-1934
    • Seidel-Rogol, B.L.1    Shadel, G.S.2
  • 32
    • 0021895138 scopus 로고
    • A new generation of Ca2+ indicators with greatly improved fluorescence properties
    • Grynkiewicz, G., Poenie, M. and Tsien, R. Y. (1985) A new generation of Ca2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 3440-3450.
    • (1985) J. Biol. Chem , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 33
    • 33947197650 scopus 로고    scopus 로고
    • Nitric oxide-evoked transient kinetics of cyclic GMP in vascular smooth muscle cells
    • Cawley, S. M., Sawyer, C. L., Brunelle, K. F., van der Vliet, A. and Dostmann, W. R. (2007) Nitric oxide-evoked transient kinetics of cyclic GMP in vascular smooth muscle cells. Cell. Signal. 19, 1023-1033.
    • (2007) Cell. Signal , vol.19 , pp. 1023-1033
    • Cawley, S.M.1    Sawyer, C.L.2    Brunelle, K.F.3    Van Der Vliet, A.4    Dostmann, W.R.5
  • 37
    • 0348134741 scopus 로고    scopus 로고
    • Redistribution of intracellular oxygen in hypoxia by nitric oxide: Effect on HIF1alpha
    • Hagen, T., Taylor, C. T., Lam, F. and Moncad, S. (2003) Redistribution of intracellular oxygen in hypoxia by nitric oxide: Effect on HIF1alpha. Science 302, 1975-1978.
    • (2003) Science , vol.302 , pp. 1975-1978
    • Hagen, T.1    Taylor, C.T.2    Lam, F.3    Moncad, S.4
  • 38
    • 18844413584 scopus 로고    scopus 로고
    • Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation-Implications for prolyl hydroxylase activity and iron
    • Callapina, M., Zhou, J., Schnitzer, S., Metzen, E., Lohr, C., Deitmer, J.W. and Brune, B. (2005) Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation-Implications for prolyl hydroxylase activity and iron. Exp. Cell Res. 306, 274-284.
    • (2005) Exp. Cell Res , vol.306 , pp. 274-284
    • Callapina, M.1    Zhou, J.2    Schnitzer, S.3    Metzen, E.4    Lohr, C.5    Deitmer, J.W.6    Brune, B.7
  • 41
    • 0031423791 scopus 로고    scopus 로고
    • Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: Implications for intracellular measurement of reactive nitrogen and oxygen species
    • Crow, J. P. (1997) Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: Implications for intracellular measurement of reactive nitrogen and oxygen species. Nitric Oxide 1, 145-157.
    • (1997) Nitric Oxide , vol.1 , pp. 145-157
    • Crow, J.P.1
  • 42
    • 4544326749 scopus 로고    scopus 로고
    • Oxidative stress-induced apoptosis in retinal photoreceptor cells is mediated by calpains and caspases and blocked by the oxygen radical scavenger CR-6
    • Sanvicens, N., Gomez-Vicente, V., Masip, I., Messeguer, A. and Cotter, T. G. (2004) Oxidative stress-induced apoptosis in retinal photoreceptor cells is mediated by calpains and caspases and blocked by the oxygen radical scavenger CR-6. J. Biol. Chem. 279, 39268-39278.
    • (2004) J. Biol. Chem , vol.279 , pp. 39268-39278
    • Sanvicens, N.1    Gomez-Vicente, V.2    Masip, I.3    Messeguer, A.4    Cotter, T.G.5
  • 43
    • 0029977549 scopus 로고    scopus 로고
    • Peroxynitrite stimulates the pyridine nucleotide-linked Ca2+ release from intact rat liver mitochondria
    • Schweizer, M. and Richter, C. (1996) Peroxynitrite stimulates the pyridine nucleotide-linked Ca2+ release from intact rat liver mitochondria. Biochemistry 35, 4524-4528.
    • (1996) Biochemistry , vol.35 , pp. 4524-4528
    • Schweizer, M.1    Richter, C.2
  • 44
    • 84883837791 scopus 로고    scopus 로고
    • Exogenous nitric oxide triggers classic ischemic preconditioning by preventing intracellular Ca(2+) overload in cardiomyocytes
    • in press
    • Rickover, O., Zinman, T., Kaplan, D. and Shainberg, A. (2007) Exogenous nitric oxide triggers classic ischemic preconditioning by preventing intracellular Ca(2+) overload in cardiomyocytes. Cell Calcium (in press).
    • (2007) Cell Calcium
    • Rickover, O.1    Zinman, T.2    Kaplan, D.3    Shainberg, A.4
  • 45
    • 34548700121 scopus 로고    scopus 로고
    • Nitric oxide regulates growth cone filopodial dynamics via ryanodine receptormediated calcium release
    • Welshhans, K. and Rehder, V. (2007) Nitric oxide regulates growth cone filopodial dynamics via ryanodine receptormediated calcium release. Eur. J. Neurosci. 26, 1537-1547.
    • (2007) Eur. J. Neurosci , vol.26 , pp. 1537-1547
    • Welshhans, K.1    Rehder, V.2
  • 47
    • 33746047996 scopus 로고    scopus 로고
    • Mu-calpain binds to lipid bilayers via the exposed hydrophobic surface of its Ca2+-activated conformation
    • Fernandez-Montalvan, A., Assfalg-Machleidt, I., Pfeiler, D., Fritz, H., Jochum, M. and Machleidt, W. (2006) Mu-calpain binds to lipid bilayers via the exposed hydrophobic surface of its Ca2+-activated conformation. Biol. Chem. 387, 617-627.
    • (2006) Biol. Chem , vol.387 , pp. 617-627
    • Fernandez-Montalvan, A.1    Assfalg-Machleidt, I.2    Pfeiler, D.3    Fritz, H.4    Jochum, M.5    MacHleidt, W.6
  • 48
    • 34249283396 scopus 로고    scopus 로고
    • Involvement of the ERK/MAP kinase signalling pathway in milli-calpain activation and myogenic cell migration
    • Leloup, L., Daury, L., Mazeres, G., Cottin, P. and Brustis, J. J. (2007) Involvement of the ERK/MAP kinase signalling pathway in milli-calpain activation and myogenic cell migration. Int. J. Biochem. Cell Biol. 39, 1177-1189.
    • (2007) Int. J. Biochem. Cell Biol , vol.39 , pp. 1177-1189
    • Leloup, L.1    Daury, L.2    Mazeres, G.3    Cottin, P.4    Brustis, J.J.5
  • 49
    • 0037165818 scopus 로고    scopus 로고
    • Mesangial cells but not hepatocytes are protected against NO/O(2)(-) cogeneration Mechanistic considerations
    • Sumbayev, V. V., Sandau, K. B. and Brune, B. (2002) Mesangial cells but not hepatocytes are protected against NO/O(2)(-) cogeneration: Mechanistic considerations. Eur. J. Pharmacol. 444, 1-11.
    • (2002) Eur J Pharmacol , vol.444 , pp. 1-11
    • Sumbayev, V.V.1    Sandau, K.B.2    Brune, B.3


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