Ubiquinone-binding site mutations in the Saccharomyces cerevisiae succinate dehydrogenase generate superoxide and lead to the accumulation of succinate

Journal of Biological Chemistry

Volumn 282, Issue 37, 2007, Pages 27518-27526

  Szeto, Samuel S W ^a   Reinke, Stacey N ^a   Sykes, Brian D ^a   Lemire, Bernard D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME ACTIVITY; GENES; OXIDATION; YEAST;

ELECTRON TRANSPORT CHAIN; ONCOGENESIS; REACTIVE OXYGEN SPECIES; SUCCINATE; SUPEROXIDE PRODUCTION;

ENZYME KINETICS;

ASPARTIC ACID; CYSTEINE; GLUTAMIC ACID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LEAD; LYSINE; SUCCINATE DEHYDROGENASE; SUCCINIC ACID; SUPEROXIDE; UBIQUINONE;

ARTICLE; BINDING SITE; CANCER; CARCINOGENESIS; ENZYME ACTIVITY; ENZYME BINDING; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEOMICS; SACCHAROMYCES CEREVISIAE;

BINDING SITES; ELECTRON TRANSPORT COMPLEX II; MUTATION; OXIDATIVE STRESS; SACCHAROMYCES CEREVISIAE; SUCCINIC ACID; SUPEROXIDES; UBIQUINONE;

SACCHAROMYCES CEREVISIAE;

EID: 34848866025     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700601200     Document Type: Article

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