-
1
-
-
0015786246
-
Antigen-T lymphocyte interactions: Inhibition by cy tochalasin B
-
Henney CS, Bubbers JE. 1973. Antigen-T lymphocyte interactions: inhibition by cy tochalasin B. J. Immunol. 111:85-90
-
(1973)
J. Immunol
, vol.111
, pp. 85-90
-
-
Henney, C.S.1
Bubbers, J.E.2
-
2
-
-
0028961573
-
Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
-
Valitutti S, Dessing M, Aktories K, Gallati H, Lanzavecchia A. 1995. Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton. J. Exp. Med. 181:577-84
-
(1995)
J. Exp. Med
, vol.181
, pp. 577-584
-
-
Valitutti, S.1
Dessing, M.2
Aktories, K.3
Gallati, H.4
Lanzavecchia, A.5
-
3
-
-
0032493028
-
Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction
-
Holsinger LJ, Graef IA, Swat W, Chi T, Bautista DM, et al. 1998. Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction. Curr. Biol. 8:563-72
-
(1998)
Curr. Biol
, vol.8
, pp. 563-572
-
-
Holsinger, L.J.1
Graef, I.A.2
Swat, W.3
Chi, T.4
Bautista, D.M.5
-
5
-
-
4444310711
-
Lymphocyte microvilli are dynamic, actin-dependent structures that do not require Wiskott-Aldrich syndrome protein (WASp) for their morphology
-
Majstoravich S, Zhang J, Nicholson-Dykstra S, Linder S, Friedrich W, et al. 2004. Lymphocyte microvilli are dynamic, actin-dependent structures that do not require Wiskott-Aldrich syndrome protein (WASp) for their morphology. Blood 104:1396-403
-
(2004)
Blood
, vol.104
, pp. 1396-1403
-
-
Majstoravich, S.1
Zhang, J.2
Nicholson-Dykstra, S.3
Linder, S.4
Friedrich, W.5
-
6
-
-
0033521607
-
1-selectin-mediated leukocyte adhesion in vivo: Microvillous distribution determines tethering efficiency, but not rolling velocity
-
Stein JV, Cheng G, Stockton BM, Fors BP, Butcher EC, von Andrian UH. 1999. 1-selectin-mediated leukocyte adhesion in vivo: microvillous distribution determines tethering efficiency, but not rolling velocity. J. Exp. Med. 189:37-50
-
(1999)
J. Exp. Med
, vol.189
, pp. 37-50
-
-
Stein, J.V.1
Cheng, G.2
Stockton, B.M.3
Fors, B.P.4
Butcher, E.C.5
von Andrian, U.H.6
-
7
-
-
0028984949
-
α4integrins mediate lymphocyte attachment and rolling under physiologic flow
-
Berlin C, Bargatze RF, Campbell JJ, von Andrian UH, Szabo MC, et al. 1995. α4integrins mediate lymphocyte attachment and rolling under physiologic flow. Cell 80:413-22
-
(1995)
Cell
, vol.80
, pp. 413-422
-
-
Berlin, C.1
Bargatze, R.F.2
Campbell, J.J.3
von Andrian, U.H.4
Szabo, M.C.5
-
8
-
-
0029817026
-
Quantitation of 1-selectin distribution on human leukocyte microvilli by immunogold labeling and electron microscopy
-
Bruehl RE, Springer TA, Bainton DF. 1996. Quantitation of 1-selectin distribution on human leukocyte microvilli by immunogold labeling and electron microscopy. J. Histochem. Cytochem. 44:835-44
-
(1996)
J. Histochem. Cytochem
, vol.44
, pp. 835-844
-
-
Bruehl, R.E.1
Springer, T.A.2
Bainton, D.F.3
-
9
-
-
0344826472
-
Chemokine stimulation of human peripheral blood T lymphocytes induces rapid dephosphorylation of ERM proteins, which facilitates loss of microvilli and polarization
-
Brown MJ, Nijhara R, Hallam JA, Gignac M, Yamada KM, et al. 2003. Chemokine stimulation of human peripheral blood T lymphocytes induces rapid dephosphorylation of ERM proteins, which facilitates loss of microvilli and polarization. Blood 102:3890-99
-
(2003)
Blood
, vol.102
, pp. 3890-3899
-
-
Brown, M.J.1
Nijhara, R.2
Hallam, J.A.3
Gignac, M.4
Yamada, K.M.5
-
10
-
-
0036024087
-
From rolling to arrest on blood vessels: Leukocyte tap dancing on endothelial integrin ligands and chemokines at subsecond contacts
-
Alon R, Feigelson S. 2002. From rolling to arrest on blood vessels: leukocyte tap dancing on endothelial integrin ligands and chemokines at subsecond contacts. Semin. Immunol. 14:93-104
-
(2002)
Semin. Immunol
, vol.14
, pp. 93-104
-
-
Alon, R.1
Feigelson, S.2
-
11
-
-
0028247080
-
Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members
-
Takeuchi K, Sato N, Kasahara H, Funayama N, Nagafuchi A, et al. 1994. Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members. J. Cell Biol. 125:1371-84
-
(1994)
J. Cell Biol
, vol.125
, pp. 1371-1384
-
-
Takeuchi, K.1
Sato, N.2
Kasahara, H.3
Funayama, N.4
Nagafuchi, A.5
-
12
-
-
0022893107
-
Morphological abnormalities in the lymphocytes of patients with the Wiscott-Aldrich Syndrome
-
Kenney D, Cairns L, Remold-O'Donnell E, Peterson J, Rosen F, Parkman R. 1986. Morphological abnormalities in the lymphocytes of patients with the Wiscott-Aldrich Syndrome. Blood 68:1329-32
-
(1986)
Blood
, vol.68
, pp. 1329-1332
-
-
Kenney, D.1
Cairns, L.2
Remold-O'Donnell, E.3
Peterson, J.4
Rosen, F.5
Parkman, R.6
-
13
-
-
0030816363
-
Defective actin reorganization and polymerization of Wiskott-Aldrich T cells in response to CD3-mediated stimulation
-
Gallego MD, Santamaria M, Pena J, Molina IJ. 1997. Defective actin reorganization and polymerization of Wiskott-Aldrich T cells in response to CD3-mediated stimulation. Blood 90:3089-97
-
(1997)
Blood
, vol.90
, pp. 3089-3097
-
-
Gallego, M.D.1
Santamaria, M.2
Pena, J.3
Molina, I.J.4
-
14
-
-
0026731846
-
T cell lines characterize events in the pathogenesis of the Wiscott-Aldrich Syndrome
-
Molina I, Kenney D, Rosen F, Remold-O'Donnell E. 1992. T cell lines characterize events in the pathogenesis of the Wiscott-Aldrich Syndrome. J. Exp. Med. 176:867-74
-
(1992)
J. Exp. Med
, vol.176
, pp. 867-874
-
-
Molina, I.1
Kenney, D.2
Rosen, F.3
Remold-O'Donnell, E.4
-
15
-
-
0030785793
-
Polarization of chemokine receptors to the leading edge during lymphocyte chemotaxis
-
Nieto M, Frade JM, Sancho D, Mellado M, Martinez AC, Sanchez-Madrid F. 1997. Polarization of chemokine receptors to the leading edge during lymphocyte chemotaxis. J. Exp. Med. 186:153-58
-
(1997)
J. Exp. Med
, vol.186
, pp. 153-158
-
-
Nieto, M.1
Frade, J.M.2
Sancho, D.3
Mellado, M.4
Martinez, A.C.5
Sanchez-Madrid, F.6
-
17
-
-
0035879352
-
Cutting edge: Integration of human T lymphocyte cytoskeleton by the cytolinker plectin
-
Brown MJ, Hallam JA, Liu Y, Yamada KM, Shaw S. 2001. Cutting edge: integration of human T lymphocyte cytoskeleton by the cytolinker plectin. J. Immunol. 167:641-45
-
(2001)
J. Immunol
, vol.167
, pp. 641-645
-
-
Brown, M.J.1
Hallam, J.A.2
Liu, Y.3
Yamada, K.M.4
Shaw, S.5
-
18
-
-
27844470230
-
Mechanisms of T cell motility and arrest: Deciphering the relationship between intra- and extracellular determinants
-
Friedman RS, Jacobelli J, Krummel MF. 2005. Mechanisms of T cell motility and arrest: deciphering the relationship between intra- and extracellular determinants. Semin. Immunol. 17:387-99
-
(2005)
Semin. Immunol
, vol.17
, pp. 387-399
-
-
Friedman, R.S.1
Jacobelli, J.2
Krummel, M.F.3
-
19
-
-
2342643498
-
A single class II myosin modulates T cell motility and stopping, but not synapse formation
-
Jacobelli J, Chmura SA, Buxton DB, Davis MM, Krummel MF. 2004. A single class II myosin modulates T cell motility and stopping, but not synapse formation. Nat. Immunol. 5:531-38
-
(2004)
Nat. Immunol
, vol.5
, pp. 531-538
-
-
Jacobelli, J.1
Chmura, S.A.2
Buxton, D.B.3
Davis, M.M.4
Krummel, M.F.5
-
20
-
-
0032700438
-
Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes
-
del Pozo MA, Vicente-Manzanares M, Tejedor R, Serrador JM, Sanchez-Madrid F. 1999. Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes. Eur. J. Immunol. 29:3609-20
-
(1999)
Eur. J. Immunol
, vol.29
, pp. 3609-3620
-
-
del Pozo, M.A.1
Vicente-Manzanares, M.2
Tejedor, R.3
Serrador, J.M.4
Sanchez-Madrid, F.5
-
21
-
-
0035996796
-
Understanding Rho/Rac biology in T-cells using animal models
-
Bustelo XR. 2002. Understanding Rho/Rac biology in T-cells using animal models. BioEssays 24:602-12
-
(2002)
BioEssays
, vol.24
, pp. 602-612
-
-
Bustelo, X.R.1
-
22
-
-
0038743116
-
Rho kinase is required for CCR7-mediated polarization and chemotaxis of T lymphocytes
-
Bardi G, Niggli V, Loetscher P. 2003. Rho kinase is required for CCR7-mediated polarization and chemotaxis of T lymphocytes. FEBS Lett. 542:79-83
-
(2003)
FEBS Lett
, vol.542
, pp. 79-83
-
-
Bardi, G.1
Niggli, V.2
Loetscher, P.3
-
23
-
-
7244247060
-
Roles of p-ERM and Rho-ROCK signaling in lymphocyte polarity and uropod formation
-
Lee JH, Katakai T, Hara T, Gonda H, Sugai M, Shimizu A. 2004. Roles of p-ERM and Rho-ROCK signaling in lymphocyte polarity and uropod formation. J. Cell Biol. 167:327-37
-
(2004)
J. Cell Biol
, vol.167
, pp. 327-337
-
-
Lee, J.H.1
Katakai, T.2
Hara, T.3
Gonda, H.4
Sugai, M.5
Shimizu, A.6
-
24
-
-
33745568317
-
A Pak- and Pix-dependent branch of the SDF-1α signalling pathway mediates T cell chemotaxis across restrictive barriers
-
Volinsky N, Gantman A, Yablonski D. 2006. A Pak- and Pix-dependent branch of the SDF-1α signalling pathway mediates T cell chemotaxis across restrictive barriers. Biochem. J. 397:213-22
-
(2006)
Biochem. J
, vol.397
, pp. 213-222
-
-
Volinsky, N.1
Gantman, A.2
Yablonski, D.3
-
25
-
-
33845439460
-
Defective chemokine-directed lymphocyte migration and development in the absence of Rho guanosine diphosphate-dissociation inhibitors α and β
-
Ishizaki H, Togawa A, Tanaka-Okamoto M, Hori K, Nishimura M, et al. 2006. Defective chemokine-directed lymphocyte migration and development in the absence of Rho guanosine diphosphate-dissociation inhibitors α and β. J. Immunol. 177:8512-21
-
(2006)
J. Immunol
, vol.177
, pp. 8512-8521
-
-
Ishizaki, H.1
Togawa, A.2
Tanaka-Okamoto, M.3
Hori, K.4
Nishimura, M.5
-
26
-
-
0038341887
-
Role of Rho-family GTPase Cdc42 in polarized expression of lymphocyte appendages
-
Ratner S, Piechocki MP, Galy A. 2003. Role of Rho-family GTPase Cdc42 in polarized expression of lymphocyte appendages. J. Leukoc. Biol. 73:830-40
-
(2003)
J. Leukoc. Biol
, vol.73
, pp. 830-840
-
-
Ratner, S.1
Piechocki, M.P.2
Galy, A.3
-
27
-
-
0020058757
-
The area of attachment of cytotoxic T lymphocytes to their target cells shows high motility and polarization of actin, but not myosin
-
Ryser JE, Rungger-Brandle E, Chaponnier C, Gabbiani G, Vassalli P. 1982. The area of attachment of cytotoxic T lymphocytes to their target cells shows high motility and polarization of actin, but not myosin. J. Immunol. 128:1159-62
-
(1982)
J. Immunol
, vol.128
, pp. 1159-1162
-
-
Ryser, J.E.1
Rungger-Brandle, E.2
Chaponnier, C.3
Gabbiani, G.4
Vassalli, P.5
-
28
-
-
0022362235
-
The reorientation of the Golgi apparatus and the microtubule-organizing center in the cytotoxic effector cell is a prerequisite in the lysis of bound target cells
-
Kupfer A, Dennert G, Singer SJ. 1985. The reorientation of the Golgi apparatus and the microtubule-organizing center in the cytotoxic effector cell is a prerequisite in the lysis of bound target cells. J. Mol. Cell. Immunol. 2:37-49
-
(1985)
J. Mol. Cell. Immunol
, vol.2
, pp. 37-49
-
-
Kupfer, A.1
Dennert, G.2
Singer, S.J.3
-
29
-
-
0028354216
-
Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: Immunofluorescence microscopy studies of Th-B antigen-presenting cell interactions
-
Kupfer H, Monks C, Kupfer A. 1994. Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopy studies of Th-B antigen-presenting cell interactions. J. Exp. Med. 179:1507-15
-
(1994)
J. Exp. Med
, vol.179
, pp. 1507-1515
-
-
Kupfer, H.1
Monks, C.2
Kupfer, A.3
-
30
-
-
0035652354
-
Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin
-
Delon J, Kaibuchi K, Germain RN. 2001. Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin. Immunity 15:691-701
-
(2001)
Immunity
, vol.15
, pp. 691-701
-
-
Delon, J.1
Kaibuchi, K.2
Germain, R.N.3
-
31
-
-
1842836367
-
The distal pole complex: A novel membrane domain distal to the immunological synapse
-
Cullinan P, Sperling AI, Burkhardt JK. 2002. The distal pole complex: a novel membrane domain distal to the immunological synapse. Immunol. Rev. 189:111-22
-
(2002)
Immunol. Rev
, vol.189
, pp. 111-122
-
-
Cullinan, P.1
Sperling, A.I.2
Burkhardt, J.K.3
-
32
-
-
1542377326
-
ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation
-
Faure S, Salazar-Fontana LI, Semichon M, Tybulewicz VL, Bismuth G, et al. 2004. ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation. Nat. Immunol. 5:272-79
-
(2004)
Nat. Immunol
, vol.5
, pp. 272-279
-
-
Faure, S.1
Salazar-Fontana, L.I.2
Semichon, M.3
Tybulewicz, V.L.4
Bismuth, G.5
-
33
-
-
0030002451
-
Proteolytic cleavage of α-actinin bycalpain in T cells stimulated with anti-CD3 monoclonal antibody
-
Selliah N, Brooks WH, Roszman TL. 1996. Proteolytic cleavage of α-actinin bycalpain in T cells stimulated with anti-CD3 monoclonal antibody. J. Immunol. 156:3215-21
-
(1996)
J. Immunol
, vol.156
, pp. 3215-3221
-
-
Selliah, N.1
Brooks, W.H.2
Roszman, T.L.3
-
34
-
-
33747091892
-
Cytoskeletal regulation couples LFA-1 conformational changes to receptor lateral mobility and clustering
-
Cairo CW, Mirchev R, Golan DE. 2006. Cytoskeletal regulation couples LFA-1 conformational changes to receptor lateral mobility and clustering. Immunity 25:297-308
-
(2006)
Immunity
, vol.25
, pp. 297-308
-
-
Cairo, C.W.1
Mirchev, R.2
Golan, D.E.3
-
35
-
-
33846250468
-
Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells
-
Morley SC, Sung J, Sun GP, Martelli MP, Bunnell SC, Bierer BE. 2007. Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells. Mol. Immunol. 44:2469-80
-
(2007)
Mol. Immunol
, vol.44
, pp. 2469-2480
-
-
Morley, S.C.1
Sung, J.2
Sun, G.P.3
Martelli, M.P.4
Bunnell, S.C.5
Bierer, B.E.6
-
38
-
-
0033063684
-
The cytoskeletal association of CD11/CD18 leukocyte integrins in phorbol ester-activated cells correlates with CD18 phosphorylation
-
Valmu L, Fagerholm S, Suila H, Gahmberg CG. 1999. The cytoskeletal association of CD11/CD18 leukocyte integrins in phorbol ester-activated cells correlates with CD18 phosphorylation. Eur. J. Immunol. 29:2107-18
-
(1999)
Eur. J. Immunol
, vol.29
, pp. 2107-2118
-
-
Valmu, L.1
Fagerholm, S.2
Suila, H.3
Gahmberg, C.G.4
-
39
-
-
34247590210
-
14-3-3 proteins bind both filamin and αLβ2 integrin in activated T cells
-
Nurmi SM, Gahmberg CG, Fagerholm SC. 2006. 14-3-3 proteins bind both filamin and αLβ2 integrin in activated T cells. Ann. NY Acad. Sci. 1090:318-25
-
(2006)
Ann. NY Acad. Sci
, vol.1090
, pp. 318-325
-
-
Nurmi, S.M.1
Gahmberg, C.G.2
Fagerholm, S.C.3
-
41
-
-
11244274075
-
The primacy of affinity over clustering in regulation of adhesiveness of the integrin αLβ2
-
Kim M, Carman CV, Yang W, Salas A, Springer TA. 2004. The primacy of affinity over clustering in regulation of adhesiveness of the integrin αLβ2. J. Cell Biol. 167:1241-53
-
(2004)
J. Cell Biol
, vol.167
, pp. 1241-1253
-
-
Kim, M.1
Carman, C.V.2
Yang, W.3
Salas, A.4
Springer, T.A.5
-
42
-
-
0042931251
-
Regulation of sustained actin dynamics by the TCR and costimulation as a mechanism of receptor localization
-
Tskvitaria-Fuller I, Rozelle AL, Yin HL, Wulfing C. 2003. Regulation of sustained actin dynamics by the TCR and costimulation as a mechanism of receptor localization. J. Immunol. 171:2287-95
-
(2003)
J. Immunol
, vol.171
, pp. 2287-2295
-
-
Tskvitaria-Fuller, I.1
Rozelle, A.L.2
Yin, H.L.3
Wulfing, C.4
-
43
-
-
27544441784
-
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
-
Campi G, Varma R, Dustin ML. 2005. Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J. Exp. Med. 202:1031-36
-
(2005)
J. Exp. Med
, vol.202
, pp. 1031-1036
-
-
Campi, G.1
Varma, R.2
Dustin, M.L.3
-
44
-
-
34249013684
-
Opposing effects of PKCO and WASp on symmetry breaking and relocation of the immunological synapse
-
Sims TN, Soos TJ, Xenias HS, Dubin-Thaler B, Hofman JM, et al. 2007. Opposing effects of PKCO and WASp on symmetry breaking and relocation of the immunological synapse. Cell 129:773-85
-
(2007)
Cell
, vol.129
, pp. 773-785
-
-
Sims, T.N.1
Soos, T.J.2
Xenias, H.S.3
Dubin-Thaler, B.4
Hofman, J.M.5
-
45
-
-
0034730182
-
The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface
-
Wulfing C, Bauch A, Crabtree GR, Davis MM. 2000. The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface. Proc. Natl. Acad. Sci. USA 97:10150-55
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10150-10155
-
-
Wulfing, C.1
Bauch, A.2
Crabtree, G.R.3
Davis, M.M.4
-
47
-
-
33646150237
-
Immune synapses in T-cell activation
-
Cemerski S, Shaw A 2006. Immune synapses in T-cell activation. Curr. Opin. Immunol. 18:298-304
-
(2006)
Curr. Opin. Immunol
, vol.18
, pp. 298-304
-
-
Cemerski, S.1
Shaw, A.2
-
48
-
-
21844440052
-
Tuning immune responses: Diversity and adaptation of the immunological synapse
-
Friedl P, den Boer AT, Gunzer M. 2005. Tuning immune responses: diversity and adaptation of the immunological synapse. Nat. Rev. Immunol. 5:532-45
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 532-545
-
-
Friedl, P.1
den Boer, A.T.2
Gunzer, M.3
-
49
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
Monks CR, Freiberg BA, Kupfer H, Sciaky N, Kupfer A. 1998. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395:82-86
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
51
-
-
27944442353
-
Altered TCR signaling from geometrically repatterned immunological synapses
-
Mossman KD, Campi G, Groves JT, Dustin ML. 2005. Altered TCR signaling from geometrically repatterned immunological synapses. Science 310:1191-93
-
(2005)
Science
, vol.310
, pp. 1191-1193
-
-
Mossman, K.D.1
Campi, G.2
Groves, J.T.3
Dustin, M.L.4
-
52
-
-
33947189706
-
The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse
-
Cemerski S, Das J, Locasale J, Arnold P, Giurisato E, et al. 2007. The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse. Immunity 26:345-55
-
(2007)
Immunity
, vol.26
, pp. 345-355
-
-
Cemerski, S.1
Das, J.2
Locasale, J.3
Arnold, P.4
Giurisato, E.5
-
53
-
-
0242497659
-
The immunological synapse balances T cell receptor signaling and degradation
-
Lee KH, Dinner AR, Tu C, Campi G, Raychaudhuri S, et al. 2003. The immunological synapse balances T cell receptor signaling and degradation. Science 302:1218-22
-
(2003)
Science
, vol.302
, pp. 1218-1222
-
-
Lee, K.H.1
Dinner, A.R.2
Tu, C.3
Campi, G.4
Raychaudhuri, S.5
-
54
-
-
0037144842
-
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
-
Bunnell SC, Hong DI, Kardon JR, Ymiazaki T, McGlade CJ, et al. 2002. T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. J. Cell Biol. 158:1263-75
-
(2002)
J. Cell Biol
, vol.158
, pp. 1263-1275
-
-
Bunnell, S.C.1
Hong, D.I.2
Kardon, J.R.3
Ymiazaki, T.4
McGlade, C.J.5
-
55
-
-
30044441433
-
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76
-
Yokosuka T, Sakata-Sogawa K, Kobayashi W, Hiroshima M, Hashimoto-Tane A, et al. 2005. Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. Nat. Immunol. 6:1253-62
-
(2005)
Nat. Immunol
, vol.6
, pp. 1253-1262
-
-
Yokosuka, T.1
Sakata-Sogawa, K.2
Kobayashi, W.3
Hiroshima, M.4
Hashimoto-Tane, A.5
-
56
-
-
33746011209
-
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster
-
Varma R, Campi G, Yokosuka T, Saito T, Dustin ML. 2006. T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity 25:117-27
-
(2006)
Immunity
, vol.25
, pp. 117-127
-
-
Varma, R.1
Campi, G.2
Yokosuka, T.3
Saito, T.4
Dustin, M.L.5
-
57
-
-
33749037156
-
The ARP2/3 complex: An actin nucleator comes of age
-
Goley ED, Welch MD. 2006. The ARP2/3 complex: an actin nucleator comes of age. Nat. Rev. Mol. Cell Biol. 7:713-26
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 713-726
-
-
Goley, E.D.1
Welch, M.D.2
-
58
-
-
33847311403
-
Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse
-
Gomez TS, Kumar K, Medeiros RB, Shimizu Y, Leibson PJ, Billadeau DD. 2007. Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse. Immunity 26:177-90
-
(2007)
Immunity
, vol.26
, pp. 177-190
-
-
Gomez, T.S.1
Kumar, K.2
Medeiros, R.B.3
Shimizu, Y.4
Leibson, P.J.5
Billadeau, D.D.6
-
59
-
-
0037112347
-
Structure of the N-WASP EVH1 domain-WIP complex: Insight into the molecular basis of Wiskott-Aldrich Syndrome
-
Volkman BF, Prehoda KE, Scott JA, Peterson FC, Lim WA. 2002. Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome. Cell 111:565-76
-
(2002)
Cell
, vol.111
, pp. 565-576
-
-
Volkman, B.F.1
Prehoda, K.E.2
Scott, J.A.3
Peterson, F.C.4
Lim, W.A.5
-
60
-
-
33846526209
-
WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP)
-
de la Fuente MA, Sasahara Y, Calamito M, Anton IM, Elkhal A, et al. 2007. WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP). Proc. Natl. Acad. Sci. USA 104:926-31
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 926-931
-
-
de la Fuente, M.A.1
Sasahara, Y.2
Calamito, M.3
Anton, I.M.4
Elkhal, A.5
-
61
-
-
0141629510
-
Wskott-Aldrich Syndrome: A model for defective actin reorganization, cell trafficking and synapse formation
-
Notarangelo LD, Ochs HD. 2003. Wskott-Aldrich Syndrome: a model for defective actin reorganization, cell trafficking and synapse formation. Curr. Opin. Immunol. 15:585-91
-
(2003)
Curr. Opin. Immunol
, vol.15
, pp. 585-591
-
-
Notarangelo, L.D.1
Ochs, H.D.2
-
62
-
-
31544454208
-
WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1α
-
Gallego MD, de la Fuente MA, Anton IM, Snapper S, Fuhlbrigge R, Geha RS. 2006. WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1α. Int. Immunol. 18:221-32
-
(2006)
Int. Immunol
, vol.18
, pp. 221-232
-
-
Gallego, M.D.1
de la Fuente, M.A.2
Anton, I.M.3
Snapper, S.4
Fuhlbrigge, R.5
Geha, R.S.6
-
63
-
-
0041845112
-
SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site
-
Zeng R, Cannon JL, Abraham RT, Way M, Billadeau DD, et al. 2003. SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site. J. Immunol. 171:1360-68
-
(2003)
J. Immunol
, vol.171
, pp. 1360-1368
-
-
Zeng, R.1
Cannon, J.L.2
Abraham, R.T.3
Way, M.4
Billadeau, D.D.5
-
64
-
-
0037241232
-
The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse
-
Badour K, Zhang J, Shi F, McGavin MK, Rampersad V, et al. 2003. The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse. Immunity 18:141-54
-
(2003)
Immunity
, vol.18
, pp. 141-154
-
-
Badour, K.1
Zhang, J.2
Shi, F.3
McGavin, M.K.4
Rampersad, V.5
-
65
-
-
0034624753
-
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
-
Kim AS, Kakalis LT, Abdul-Manan N, Liu GA, Rosen MK. 2000. Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein. Nature 404:151-58
-
(2000)
Nature
, vol.404
, pp. 151-158
-
-
Kim, A.S.1
Kakalis, L.T.2
Abdul-Manan, N.3
Liu, G.A.4
Rosen, M.K.5
-
66
-
-
0038392871
-
Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP
-
Torres E, Rosen MK. 2003. Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP. Mol. Cell 11:1215-27
-
(2003)
Mol. Cell
, vol.11
, pp. 1215-1227
-
-
Torres, E.1
Rosen, M.K.2
-
67
-
-
0347915637
-
Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation
-
Badour K, Zhang J, Shi F, Leng Y, Collins M, Siminovitch KA. 2004. Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation. J. Exp. Med. 199:99-112
-
(2004)
J. Exp. Med
, vol.199
, pp. 99-112
-
-
Badour, K.1
Zhang, J.2
Shi, F.3
Leng, Y.4
Collins, M.5
Siminovitch, K.A.6
-
68
-
-
33645643086
-
Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP
-
Torres E, Rosen MK. 2006. Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP. J. Biol. Chem. 281:3513-20
-
(2006)
J. Biol. Chem
, vol.281
, pp. 3513-3520
-
-
Torres, E.1
Rosen, M.K.2
-
69
-
-
30044446991
-
The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation
-
Nolz JC, Gomez TS, Zhu P, Li S, Medeiros RB, et al. 2006. The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation. Curr. Biol. 16:24-34
-
(2006)
Curr. Biol
, vol.16
, pp. 24-34
-
-
Nolz, J.C.1
Gomez, T.S.2
Zhu, P.3
Li, S.4
Medeiros, R.B.5
-
70
-
-
0036199184
-
Vavl controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells
-
Krawczyk C, Oliveira-dos-Santos A, Sasaki T, Griffiths E, Ohashi PS, et al. 2002. Vavl controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells. Immunity 16:331-43
-
(2002)
Immunity
, vol.16
, pp. 331-343
-
-
Krawczyk, C.1
Oliveira-dos-Santos, A.2
Sasaki, T.3
Griffiths, E.4
Ohashi, P.S.5
-
71
-
-
3242762840
-
Differential roles for Wiskott-Aldrich syndrome protein in immune synapse formation and IL-2 production
-
Cannon JL, Burkhardt JK. 2004. Differential roles for Wiskott-Aldrich syndrome protein in immune synapse formation and IL-2 production. J. Immunol. 173:1658-62
-
(2004)
J. Immunol
, vol.173
, pp. 1658-1662
-
-
Cannon, J.L.1
Burkhardt, J.K.2
-
72
-
-
30044438580
-
Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling
-
Zipfel PA, Bunnell SC, Witherow DS, Gu JJ, Chislock EM, et al. 2006. Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling. Curr. Biol. 16:35-46
-
(2006)
Curr. Biol
, vol.16
, pp. 35-46
-
-
Zipfel, P.A.1
Bunnell, S.C.2
Witherow, D.S.3
Gu, J.J.4
Chislock, E.M.5
-
73
-
-
0032403083
-
WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac
-
Miki H, Suetsugu S, Takenawa T. 1998. WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac. EMBO J. 17:6932-41
-
(1998)
EMBO J
, vol.17
, pp. 6932-6941
-
-
Miki, H.1
Suetsugu, S.2
Takenawa, T.3
-
74
-
-
2342483041
-
Abil is essential for the formation and activation of a WAVE2 signalling complex
-
Innocenti M, Zucconi A, Disanza A, Frittoli E, Areces LB, et al. 2004. Abil is essential for the formation and activation of a WAVE2 signalling complex. Nat. Cell Biol. 6:319-27
-
(2004)
Nat. Cell Biol
, vol.6
, pp. 319-327
-
-
Innocenti, M.1
Zucconi, A.2
Disanza, A.3
Frittoli, E.4
Areces, L.B.5
-
75
-
-
0034619847
-
IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling
-
Miki H, Yamaguchi H, Suetsugu S, Takenawa T. 2000. IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling. Nature 408:732-35
-
(2000)
Nature
, vol.408
, pp. 732-735
-
-
Miki, H.1
Yamaguchi, H.2
Suetsugu, S.3
Takenawa, T.4
-
76
-
-
12844251861
-
Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation
-
Leng Y, Zhang J, Badour K, Arpaia E, Freeman S, et al. 2005. Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation. Proc. Natl. Acad. Sci. USA 102:1098-103
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1098-1103
-
-
Leng, Y.1
Zhang, J.2
Badour, K.3
Arpaia, E.4
Freeman, S.5
-
77
-
-
27844539337
-
The coiled-coil domain is required for HS1 to bind to F-actin and activate Arp2/3 complex
-
Hao JJ, Zhu J, Zhou K, Smith N, Zhan X. 2005. The coiled-coil domain is required for HS1 to bind to F-actin and activate Arp2/3 complex. J. Biol. Chem. 280:37988-94
-
(2005)
J. Biol. Chem
, vol.280
, pp. 37988-37994
-
-
Hao, J.J.1
Zhu, J.2
Zhou, K.3
Smith, N.4
Zhan, X.5
-
78
-
-
0035090317
-
Activation of Arp2/3 complex-mediated actin polymerization by cortactin
-
Uruno T, Liu J, Zhang P, Fan Y, Egile C, et al. 2001. Activation of Arp2/3 complex-mediated actin polymerization by cortactin. Nat. Cell Biol. 3:259-66
-
(2001)
Nat. Cell Biol
, vol.3
, pp. 259-266
-
-
Uruno, T.1
Liu, J.2
Zhang, P.3
Fan, Y.4
Egile, C.5
-
79
-
-
0038752667
-
Haematopoietic lineage cell-specific protein 1 (HS1) promotes actin-related protein (Arp) 2/3 complex-mediated actin polymerization
-
Uruno T, Zhang P, Liu J, Hao JJ, Zhan X. 2003. Haematopoietic lineage cell-specific protein 1 (HS1) promotes actin-related protein (Arp) 2/3 complex-mediated actin polymerization. Biochem. J. 371:485-93
-
(2003)
Biochem. J
, vol.371
, pp. 485-493
-
-
Uruno, T.1
Zhang, P.2
Liu, J.3
Hao, J.J.4
Zhan, X.5
-
80
-
-
0035814938
-
Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation
-
Weaver AM, Karginov AV, Kinley AW, Weed SA, Li Y, et al. 2001. Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation. Curr. Biol. 11:370-74
-
(2001)
Curr. Biol
, vol.11
, pp. 370-374
-
-
Weaver, A.M.1
Karginov, A.V.2
Kinley, A.W.3
Weed, S.A.4
Li, Y.5
-
81
-
-
33744981370
-
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse
-
Gomez TS, McCarney SD, Carrizosa E, Labno CM, Comiskey EO, et al. 2006. HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse. Immunity 24:741-52
-
(2006)
Immunity
, vol.24
, pp. 741-752
-
-
Gomez, T.S.1
McCarney, S.D.2
Carrizosa, E.3
Labno, C.M.4
Comiskey, E.O.5
-
82
-
-
1242341975
-
Cofilin peptide homologs interfere with immunological synapse formation and T cell activation
-
Eibert SM, Lee KH, Pipkorn R, Sester U, Wabnitz GH, et al. 2004. Cofilin peptide homologs interfere with immunological synapse formation and T cell activation. Proc. Natl. Acad. Sci. USA 101:1957-62
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1957-1962
-
-
Eibert, S.M.1
Lee, K.H.2
Pipkorn, R.3
Sester, U.4
Wabnitz, G.H.5
-
84
-
-
0034536444
-
The serine phosphatases PP1 and PP2A associate with and activate the actin-binding protein cofilin in human T lymphocytes
-
Ambach A, Saunus J, Konstandin M, Wesselborg S, Meuer SC, Samstag Y. 2000. The serine phosphatases PP1 and PP2A associate with and activate the actin-binding protein cofilin in human T lymphocytes. Eur. J. Immunol. 30:3422-31
-
(2000)
Eur. J. Immunol
, vol.30
, pp. 3422-3431
-
-
Ambach, A.1
Saunus, J.2
Konstandin, M.3
Wesselborg, S.4
Meuer, S.C.5
Samstag, Y.6
-
85
-
-
0026499536
-
Dephosphorylation of pp19: A common second signal for human T cell activation mediated through different accessory molecules
-
Samstag Y, Henning SW, Bader A, Meuer SC. 1992. Dephosphorylation of pp19: a common second signal for human T cell activation mediated through different accessory molecules. Int. Immunol. 4:1255-62
-
(1992)
Int. Immunol
, vol.4
, pp. 1255-1262
-
-
Samstag, Y.1
Henning, S.W.2
Bader, A.3
Meuer, S.C.4
-
86
-
-
0034599541
-
Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator- stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton
-
Krause M, Sechi AS, Konradt M, Monner D, Gertler FB, Wehland J. 2000. Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator- stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton. J. Cell Biol. 149:181-94
-
(2000)
J. Cell Biol
, vol.149
, pp. 181-194
-
-
Krause, M.1
Sechi, A.S.2
Konradt, M.3
Monner, D.4
Gertler, F.B.5
Wehland, J.6
-
87
-
-
33646864565
-
Staying in shape with formins
-
Faix J, Grosse R. 2006. Staying in shape with formins. Dev. Cell 10:693-706
-
(2006)
Dev. Cell
, vol.10
, pp. 693-706
-
-
Faix, J.1
Grosse, R.2
-
88
-
-
0345687479
-
Ena/VASP proteins: Regulators of the actin cytoskeleton and cell migration
-
Krause M, Dent EW, Bear JE, Loureiro JJ, Gertler FB. 2003. Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration. Annu. Rev. Cell Dev. Biol. 19:541-64
-
(2003)
Annu. Rev. Cell Dev. Biol
, vol.19
, pp. 541-564
-
-
Krause, M.1
Dent, E.W.2
Bear, J.E.3
Loureiro, J.J.4
Gertler, F.B.5
-
89
-
-
21044451441
-
Polycomb group protein ezh2 controls actin polymerization and cell signaling
-
Su IH, Dobenecker MW, Dickinson E, Oser M, Basavaraj A, et al. 2005. Polycomb group protein ezh2 controls actin polymerization and cell signaling. Cell 121:425-36
-
(2005)
Cell
, vol.121
, pp. 425-436
-
-
Su, I.H.1
Dobenecker, M.W.2
Dickinson, E.3
Oser, M.4
Basavaraj, A.5
-
90
-
-
33644652364
-
Lysine methylation and 'signaling memory'
-
Su IH, Tarakhovsky A. 2006. Lysine methylation and 'signaling memory'. Curr. Opin. Immunol. 18:152-57
-
(2006)
Curr. Opin. Immunol
, vol.18
, pp. 152-157
-
-
Su, I.H.1
Tarakhovsky, A.2
-
91
-
-
20144372910
-
Dynamin 2 regulates T cell activation by controlling actin polymerization at the immunological synapse
-
Gomez TS, Hamann MJ, McCarney S, Savoy DN, Lubking CM, et al. 2005. Dynamin 2 regulates T cell activation by controlling actin polymerization at the immunological synapse. Nat. Immunol. 6:261-70
-
(2005)
Nat. Immunol
, vol.6
, pp. 261-270
-
-
Gomez, T.S.1
Hamann, M.J.2
McCarney, S.3
Savoy, D.N.4
Lubking, C.M.5
-
92
-
-
33744508200
-
Dynamin as a mover and pincher during cell migration and invasion
-
Kruchten AE, McNiven MA. 2006. Dynamin as a mover and pincher during cell migration and invasion. J. Cell Sci. 119:1683-90
-
(2006)
J. Cell Sci
, vol.119
, pp. 1683-1690
-
-
Kruchten, A.E.1
McNiven, M.A.2
-
93
-
-
1842836367
-
The distal pole complex: A novel membrane domain distal to the immunological synapse
-
Cullinan P, Sperling AI, Burkhardt JK. 2002. The distal pole complex: a novel membrane domain distal to the immunological synapse. Immunol. Rev. 189:111-22
-
(2002)
Immunol. Rev
, vol.189
, pp. 111-122
-
-
Cullinan, P.1
Sperling, A.I.2
Burkhardt, J.K.3
-
94
-
-
18244364886
-
ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse
-
Allenspach EJ, Cullinan P, Tong J, Tang Q, Tesciuba AG, et al. 2001. ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse. Immunity 15:739-50
-
(2001)
Immunity
, vol.15
, pp. 739-750
-
-
Allenspach, E.J.1
Cullinan, P.2
Tong, J.3
Tang, Q.4
Tesciuba, A.G.5
-
95
-
-
0037090303
-
Polar redistribution of the sialoglycoprotein CD43: Implications for T cell function
-
Savage ND, Kimzey SL, Bromley SK, Johnson KG, Dustin ML, Green JM. 2002. Polar redistribution of the sialoglycoprotein CD43: implications for T cell function. J. Immunol. 168:3740-46
-
(2002)
J. Immunol
, vol.168
, pp. 3740-3746
-
-
Savage, N.D.1
Kimzey, S.L.2
Bromley, S.K.3
Johnson, K.G.4
Dustin, M.L.5
Green, J.M.6
-
96
-
-
20444445916
-
A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation
-
Ludford-Menting MJ, Oliaro J, Sacirbegovic F, Cheah ET, Pedersen N, et al. 2005. A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation. Immunity 22:737-48
-
(2005)
Immunity
, vol.22
, pp. 737-748
-
-
Ludford-Menting, M.J.1
Oliaro, J.2
Sacirbegovic, F.3
Cheah, E.T.4
Pedersen, N.5
-
97
-
-
0035654721
-
The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation
-
Roumier A, Olivo-Marin JC, Arpin M, Michel F, Martin M, et al. 2001. The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation. Immunity 15:715-28
-
(2001)
Immunity
, vol.15
, pp. 715-728
-
-
Roumier, A.1
Olivo-Marin, J.C.2
Arpin, M.3
Michel, F.4
Martin, M.5
-
98
-
-
33846514807
-
Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-κB transcription factors
-
Round JL, Humphries LA, Tomassian T, Mittelstadt P, Zhang M, Miceli MC. 2007. Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-κB transcription factors. Nat. Immunol. 8:154-61
-
(2007)
Nat. Immunol
, vol.8
, pp. 154-161
-
-
Round, J.L.1
Humphries, L.A.2
Tomassian, T.3
Mittelstadt, P.4
Zhang, M.5
Miceli, M.C.6
-
99
-
-
13644268540
-
Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells
-
Round JL, Tomassian T, Zhang M, Patel V, Schoenberger SP, Miceli MC. 2005. Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells. J. Exp. Med. 201:419-30
-
(2005)
J. Exp. Med
, vol.201
, pp. 419-430
-
-
Round, J.L.1
Tomassian, T.2
Zhang, M.3
Patel, V.4
Schoenberger, S.P.5
Miceli, M.C.6
-
100
-
-
0041976988
-
The tyrosine phosphatase CD148 is excluded from the immunologic synapse and down-regulates prolonged T cell signaling
-
Lin J, Weiss A. 2003. The tyrosine phosphatase CD148 is excluded from the immunologic synapse and down-regulates prolonged T cell signaling. J. Cell Biol. 162:673-82
-
(2003)
J. Cell Biol
, vol.162
, pp. 673-682
-
-
Lin, J.1
Weiss, A.2
-
101
-
-
0242664138
-
Regulation of T-cell activation by phosphodiesterase 4B2 requires its dynamic redistribution during immunological synapse formation
-
Arp J, Kirchhof MG, Baroja ML, Nazarian SH, Chau TA, et al. 2003. Regulation of T-cell activation by phosphodiesterase 4B2 requires its dynamic redistribution during immunological synapse formation. Mol. Cell. Biol. 23:8042-57
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 8042-8057
-
-
Arp, J.1
Kirchhof, M.G.2
Baroja, M.L.3
Nazarian, S.H.4
Chau, T.A.5
-
102
-
-
33645960166
-
PKCC at the crossroad of NF-κB and Jak1/Stat6 signaling pathways
-
Moscat J, Rennert P, Diaz-Meco MT. 2006. PKCC at the crossroad of NF-κB and Jak1/Stat6 signaling pathways. Cell Death Differ. 13:702-11
-
(2006)
Cell Death Differ
, vol.13
, pp. 702-711
-
-
Moscat, J.1
Rennert, P.2
Diaz-Meco, M.T.3
-
103
-
-
0036853106
-
Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse
-
Costello PS, Gallagher M, Cantrell DA. 2002. Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse. Nat. Immunol. 3:1082-89
-
(2002)
Nat. Immunol
, vol.3
, pp. 1082-1089
-
-
Costello, P.S.1
Gallagher, M.2
Cantrell, D.A.3
-
104
-
-
0037338890
-
TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways
-
Stefanova I, Hemmer B, Vergelli M, Martin R, Biddison WE, Germain RN. 2003. TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways. Nat. Immunol. 4:248-54
-
(2003)
Nat. Immunol
, vol.4
, pp. 248-254
-
-
Stefanova, I.1
Hemmer, B.2
Vergelli, M.3
Martin, R.4
Biddison, W.E.5
Germain, R.N.6
-
105
-
-
0037080345
-
Cutting edge: Negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly
-
Itoh K, Sakakibara M, Yamasaki S, Takeuchi A, Arase H, et al. 2002. Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly. J. Immunol. 168:541-44
-
(2002)
J. Immunol
, vol.168
, pp. 541-544
-
-
Itoh, K.1
Sakakibara, M.2
Yamasaki, S.3
Takeuchi, A.4
Arase, H.5
-
106
-
-
33847290896
-
Regulation of signal transducer and activator of transcription signaling by the tyrosine phosphatase PTP-BL
-
Nakahira M, Tanaka T, Robson BE, Mizgerd JP, Grusby MJ. 2007. Regulation of signal transducer and activator of transcription signaling by the tyrosine phosphatase PTP-BL. Immunity 26:163-76
-
(2007)
Immunity
, vol.26
, pp. 163-176
-
-
Nakahira, M.1
Tanaka, T.2
Robson, B.E.3
Mizgerd, J.P.4
Grusby, M.J.5
-
107
-
-
7444223478
-
PKC9 is required for the activation of human T lymphocytes induced by CD43 engagement
-
del Rio R, Rincon M, Layseca-Espinosa E, Fierro NA, Rosenstein Y, Pedraza-Alva G. 2004. PKC9 is required for the activation of human T lymphocytes induced by CD43 engagement. Biochem. Biophys. Res. Commun. 325:133-43
-
(2004)
Biochem. Biophys. Res. Commun
, vol.325
, pp. 133-143
-
-
del Rio, R.1
Rincon, M.2
Layseca-Espinosa, E.3
Fierro, N.A.4
Rosenstein, Y.5
Pedraza-Alva, G.6
-
108
-
-
0029065528
-
CD43 is a murine T cell costimulatory receptor that functions independently of CD28
-
Sperling M, Green JM, Mosley RL, Smith PL, DiPaolo RJ, et al. 1995. CD43 is a murine T cell costimulatory receptor that functions independently of CD28. J. Exp. Med. 182:139-46
-
(1995)
J. Exp. Med
, vol.182
, pp. 139-146
-
-
Sperling, M.1
Green, J.M.2
Mosley, R.L.3
Smith, P.L.4
DiPaolo, R.J.5
-
109
-
-
33845474041
-
Ligation of the cell surface receptor, CD46, alters T cell polarity and response to antigen presentation
-
Oliaro J, Pasam A, Waterhouse NJ, Browne KA, Ludford-Menting MJ, et al. 2006. Ligation of the cell surface receptor, CD46, alters T cell polarity and response to antigen presentation. Proc. Natl. Acad. Sci. USA 103:18685-90
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 18685-18690
-
-
Oliaro, J.1
Pasam, A.2
Waterhouse, N.J.3
Browne, K.A.4
Ludford-Menting, M.J.5
-
111
-
-
0036171199
-
Activation of the PKB/AKT pathway by ICAM-2
-
Perez OD, Kinoshita S, Hitoshi Y, Payan DG, Kitamura T, et al. 2002. Activation of the PKB/AKT pathway by ICAM-2. Immunity 16:51-65
-
(2002)
Immunity
, vol.16
, pp. 51-65
-
-
Perez, O.D.1
Kinoshita, S.2
Hitoshi, Y.3
Payan, D.G.4
Kitamura, T.5
-
112
-
-
0034597013
-
CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: A novel regulatory mechanism of the CD95 apoptotic pathway
-
Parlato S, Giammarioli AM, Logozzi M, Lozupone F, Matarrese P, et al. 2000. CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway. EMBO J. 19:5123-34
-
(2000)
EMBO J
, vol.19
, pp. 5123-5134
-
-
Parlato, S.1
Giammarioli, A.M.2
Logozzi, M.3
Lozupone, F.4
Matarrese, P.5
-
113
-
-
10744229269
-
Identification and relevance of the CD95-binding domain in the N-terminal region of ezrin
-
Lozupone F, Lugini L, Matarrese P, Luciani F, Federici C, et al. 2004. Identification and relevance of the CD95-binding domain in the N-terminal region of ezrin. J. Biol. Chem. 279:9199-207
-
(2004)
J. Biol. Chem
, vol.279
, pp. 9199-9207
-
-
Lozupone, F.1
Lugini, L.2
Matarrese, P.3
Luciani, F.4
Federici, C.5
-
114
-
-
33846100727
-
Self-masking in an intact ERM-merlin protein: An active role for the central α-helical domain
-
Li Q, Nance MR, Kulikauskas R, Nyberg K, Fehon R, et al. 2007. Self-masking in an intact ERM-merlin protein: an active role for the central α-helical domain. J. Mol. Biol. 365:1446-59
-
(2007)
J. Mol. Biol
, vol.365
, pp. 1446-1459
-
-
Li, Q.1
Nance, M.R.2
Kulikauskas, R.3
Nyberg, K.4
Fehon, R.5
-
116
-
-
6344219506
-
Rac1 mediates collapse of microvilli on chemokine-activated T lymphocytes
-
Nijhara R, van Hennik PB, Gignac ML, Kruhlak MJ, Hordijk PL, et al. 2004. Rac1 mediates collapse of microvilli on chemokine-activated T lymphocytes. J. Immunol. 173:4985-93
-
(2004)
J. Immunol
, vol.173
, pp. 4985-4993
-
-
Nijhara, R.1
van Hennik, P.B.2
Gignac, M.L.3
Kruhlak, M.J.4
Hordijk, P.L.5
-
117
-
-
33745034465
-
Measles virus contact with T cells impedes cytoskeletal remodeling associated with spreading, polarization, and CD3 clustering
-
Muller N, Avota E, Schneider-Schaulies J, Harms H, Krohne G, Schneider-Schaulies S. 2006. Measles virus contact with T cells impedes cytoskeletal remodeling associated with spreading, polarization, and CD3 clustering. Traffic 7:849-58
-
(2006)
Traffic
, vol.7
, pp. 849-858
-
-
Muller, N.1
Avota, E.2
Schneider-Schaulies, J.3
Harms, H.4
Krohne, G.5
Schneider-Schaulies, S.6
-
118
-
-
0028141777
-
Ligation of CD4 surface antigen induces rapid tyrosine phosphorylation of the cytoskeletal protein ezrin
-
Thuillier L, Hivroz C, Fagard R, Andreoli C, Mangeat P. 1994. Ligation of CD4 surface antigen induces rapid tyrosine phosphorylation of the cytoskeletal protein ezrin. Cell. Immunol. 156:322-31
-
(1994)
Cell. Immunol
, vol.156
, pp. 322-331
-
-
Thuillier, L.1
Hivroz, C.2
Fagard, R.3
Andreoli, C.4
Mangeat, P.5
-
119
-
-
0026697728
-
Identification of ezrin as an 81-kDa tyrosine-phosphorylated protein in T cells
-
Egerton M, Burgess WH, Chen D, Druker BJ, Bretscher A, Samelson LE. 1992. Identification of ezrin as an 81-kDa tyrosine-phosphorylated protein in T cells. J. Immunol. 149:1847-52
-
(1992)
J. Immunol
, vol.149
, pp. 1847-1852
-
-
Egerton, M.1
Burgess, W.H.2
Chen, D.3
Druker, B.J.4
Bretscher, A.5
Samelson, L.E.6
-
120
-
-
0037472801
-
Ezrin is a substrate for Lck in T cells
-
Autero M, Heiska L, Ronnstrand L, Vaheri A, Gahmberg CG, Carpen O. 2003. Ezrin is a substrate for Lck in T cells. FEBS Lett. 535:82-86
-
(2003)
FEBS Lett
, vol.535
, pp. 82-86
-
-
Autero, M.1
Heiska, L.2
Ronnstrand, L.3
Vaheri, A.4
Gahmberg, C.G.5
Carpen, O.6
-
121
-
-
0033594950
-
Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway
-
Gautreau A, Poullet P, Louvard D, Arpin AI. 1999. Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway. Proc. Natl. Acad. Sci. USA 96:7300-5
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7300-7305
-
-
Gautreau, A.1
Poullet, P.2
Louvard, D.3
Arpin, A.I.4
-
122
-
-
0037127291
-
The cytoplasmic tail of 1-selectin interacts with members of the Ezrin-Radixin-Moesin (ERM) family of proteins: Cell activation-dependent binding of Moesin but not Ezrin
-
Ivetic A, Deka J, Ridley A, Ager A. 2002. The cytoplasmic tail of 1-selectin interacts with members of the Ezrin-Radixin-Moesin (ERM) family of proteins: cell activation-dependent binding of Moesin but not Ezrin. J. Biol. Chem. 277:2321-29
-
(2002)
J. Biol. Chem
, vol.277
, pp. 2321-2329
-
-
Ivetic, A.1
Deka, J.2
Ridley, A.3
Ager, A.4
-
123
-
-
33645746316
-
The PAR-aPKC system: Lessons in polarity
-
Suzuki A, Ohno S. 2006. The PAR-aPKC system: lessons in polarity. J. Cell Sci. 119:979-87
-
(2006)
J. Cell Sci
, vol.119
, pp. 979-987
-
-
Suzuki, A.1
Ohno, S.2
-
124
-
-
20444480611
-
PDZ domains and the politics of polarity in lymphocytes
-
Xavier R, Seed B. 2005. PDZ domains and the politics of polarity in lymphocytes. Immunity 22:655-56
-
(2005)
Immunity
, vol.22
, pp. 655-656
-
-
Xavier, R.1
Seed, B.2
-
125
-
-
4444382955
-
Discs large (Dlg1) complexes in lymphocyte activation
-
Xavier R, Rabizadeh S, Ishiguro K, Andre N, Ortiz JB, et al. 2004. Discs large (Dlg1) complexes in lymphocyte activation. J. Cell Biol. 166:173-78
-
(2004)
J. Cell Biol
, vol.166
, pp. 173-178
-
-
Xavier, R.1
Rabizadeh, S.2
Ishiguro, K.3
Andre, N.4
Ortiz, J.B.5
-
126
-
-
33947283144
-
The Par polarity complex regulates Rap1-and chemokine-induced T cell polarization
-
Gerard A, Mertens AE, Van Der Kammen RA, Collard JG. 2007. The Par polarity complex regulates Rap1-and chemokine-induced T cell polarization. J. Cell Biol. 176:863-75
-
(2007)
J. Cell Biol
, vol.176
, pp. 863-875
-
-
Gerard, A.1
Mertens, A.E.2
Van Der Kammen, R.A.3
Collard, J.G.4
-
127
-
-
33947730608
-
Asymmetric T lymphocyte division in the initiation of adaptive immune responses
-
Chang JT, Palanivel VR, Kinjyo I, Schambach F, Intlekofer AM, et al. 2007. Asymmetric T lymphocyte division in the initiation of adaptive immune responses. Science 315:1687-91
-
(2007)
Science
, vol.315
, pp. 1687-1691
-
-
Chang, J.T.1
Palanivel, V.R.2
Kinjyo, I.3
Schambach, F.4
Intlekofer, A.M.5
-
128
-
-
0037304542
-
All roads lead to actin: The intimate relationship between TCR signaling and the cytoskeleton
-
Fuller CL, Braciale VL, Samelson LE. 2003. All roads lead to actin: the intimate relationship between TCR signaling and the cytoskeleton. Immunol. Rev. 191:220-36
-
(2003)
Immunol. Rev
, vol.191
, pp. 220-236
-
-
Fuller, C.L.1
Braciale, V.L.2
Samelson, L.E.3
-
129
-
-
0036362481
-
Regulation of Vav proteins by intramolecular events
-
Bustelo XR. 2002. Regulation of Vav proteins by intramolecular events. Front. Biosci. 7:d24-30
-
(2002)
Front. Biosci
, vol.7
-
-
Bustelo, X.R.1
-
130
-
-
19944431032
-
Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton
-
Dombroski D, Houghtling RA, Labno CM, Precht P, Takesono A, et al. 2005. Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton . J. Immunol. 174:1385-92
-
(2005)
J. Immunol
, vol.174
, pp. 1385-1392
-
-
Dombroski, D.1
Houghtling, R.A.2
Labno, C.M.3
Precht, P.4
Takesono, A.5
-
131
-
-
10744228513
-
Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP
-
Labno CM, Lewis CM, You D, Leung DW, Takesono A, et al. 2003. Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP. Curr. Biol. 13:1619-24
-
(2003)
Curr. Biol
, vol.13
, pp. 1619-1624
-
-
Labno, C.M.1
Lewis, C.M.2
You, D.3
Leung, D.W.4
Takesono, A.5
-
132
-
-
13144259727
-
Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor
-
Fischer KD, Kong YY, Nishina H, Tedford K, Marengere LE, et al. 1998. Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor. Curr. Biol. 8:554-62
-
(1998)
Curr. Biol
, vol.8
, pp. 554-562
-
-
Fischer, K.D.1
Kong, Y.Y.2
Nishina, H.3
Tedford, K.4
Marengere, L.E.5
-
133
-
-
0034292369
-
CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation
-
Michel F, Mangino G, Attal-Bonnefoy G, Tuosto L, Alcover A, et al. 2000. CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation. J. Immunol. 165:3820-29
-
(2000)
J. Immunol
, vol.165
, pp. 3820-3829
-
-
Michel, F.1
Mangino, G.2
Attal-Bonnefoy, G.3
Tuosto, L.4
Alcover, A.5
-
134
-
-
15144353776
-
Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav
-
Han J, Luby-Phelps K, Das B, Shu X, Xia Y, et al. 1998. Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav. Science 279:558-60
-
(1998)
Science
, vol.279
, pp. 558-560
-
-
Han, J.1
Luby-Phelps, K.2
Das, B.3
Shu, X.4
Xia, Y.5
-
135
-
-
4143074805
-
Tec kinases: Shaping T-cell activation through actin
-
Finkelstein LD, Schwartzberg PL. 2004. Tec kinases: shaping T-cell activation through actin. Trends Cell Biol. 14:443-51
-
(2004)
Trends Cell Biol
, vol.14
, pp. 443-451
-
-
Finkelstein, L.D.1
Schwartzberg, P.L.2
-
136
-
-
31144470414
-
Phosphatidylinositol 3-kinase functions as a Ras effector in the signaling cascade that regulates dephosphorylation of the actin-remodeling protein cofilin after costimulation of untransformed human T lymphocytes
-
Wabnitz GH, Nebl G, Klemke M, Schroder AJ, Samstag Y. 2006. Phosphatidylinositol 3-kinase functions as a Ras effector in the signaling cascade that regulates dephosphorylation of the actin-remodeling protein cofilin after costimulation of untransformed human T lymphocytes. J. Immunol. 176:1668-74
-
(2006)
J. Immunol
, vol.176
, pp. 1668-1674
-
-
Wabnitz, G.H.1
Nebl, G.2
Klemke, M.3
Schroder, A.J.4
Samstag, Y.5
-
137
-
-
34147144013
-
Costimulation induced phosphorylation of 1-plastin facilitates surface transport of the T cell activation molecules CD69 and CD25
-
Wabnitz GH, Kocher T, Lohneis P, Stober C, Konstandin MH, et al. 2007. Costimulation induced phosphorylation of 1-plastin facilitates surface transport of the T cell activation molecules CD69 and CD25. Eur. J. Immunol. 37:649-62
-
(2007)
Eur. J. Immunol
, vol.37
, pp. 649-662
-
-
Wabnitz, G.H.1
Kocher, T.2
Lohneis, P.3
Stober, C.4
Konstandin, M.H.5
-
138
-
-
0037079628
-
Rho GTPases link cytoskeletal rearrangements and activation processes induced via the tetraspanin CD82 in T lymphocytes
-
Delaguillaumie A, Lagaudriere-Gesbert C, Popoff MR, Conjeaud H. 2002. Rho GTPases link cytoskeletal rearrangements and activation processes induced via the tetraspanin CD82 in T lymphocytes. J. Cell Sci. 115:433-43
-
(2002)
J. Cell Sci
, vol.115
, pp. 433-443
-
-
Delaguillaumie, A.1
Lagaudriere-Gesbert, C.2
Popoff, M.R.3
Conjeaud, H.4
-
139
-
-
0035892881
-
CD46/CD3 costimulation induces morphological changes of human T cells and activation of Vav, Rac, and extracellular signal-regulated kinase mitogen-activated protein kinase
-
Zaffran Y, Destaing O, Roux A, Ory S, Nheu T, et al. 2001. CD46/CD3 costimulation induces morphological changes of human T cells and activation of Vav, Rac, and extracellular signal-regulated kinase mitogen-activated protein kinase. J. Immunol. 167:6780-85
-
(2001)
J. Immunol
, vol.167
, pp. 6780-6785
-
-
Zaffran, Y.1
Destaing, O.2
Roux, A.3
Ory, S.4
Nheu, T.5
-
140
-
-
33845350068
-
AILIM/ICOS-mediated elongation of activated T cells is regulated by both the PI3-kinase/Akt and Rho family cascade
-
Nukada Y, Okamoto N, Konakahara S, Tezuka K, Ohashi K, et al. 2006. AILIM/ICOS-mediated elongation of activated T cells is regulated by both the PI3-kinase/Akt and Rho family cascade. Int. Immunol. 18:1815-24
-
(2006)
Int. Immunol
, vol.18
, pp. 1815-1824
-
-
Nukada, Y.1
Okamoto, N.2
Konakahara, S.3
Tezuka, K.4
Ohashi, K.5
-
141
-
-
0033230229
-
Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes
-
Zhang J, Shehabeldin A, da Cruz LA, Butler J, Somani AK, et al. 1999. Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes. J. Exp. Med. 190:1329-42
-
(1999)
J. Exp. Med
, vol.190
, pp. 1329-1342
-
-
Zhang, J.1
Shehabeldin, A.2
da Cruz, L.A.3
Butler, J.4
Somani, A.K.5
-
142
-
-
28444431954
-
2 005. Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome
-
Cianferoni A, Massaad M, Feske S, de la Fuente MA, Gallego L, et al. 2 005. Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome. J. Allergy Clin. Immunol. 116:1364-71
-
J. Allergy Clin. Immunol
, vol.116
, pp. 1364-1371
-
-
Cianferoni, A.1
Massaad, M.2
Feske, S.3
de la Fuente, M.A.4
Gallego, L.5
-
143
-
-
0032981244
-
The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-κB pathways
-
Costello PS, Walters AE, Mee PJ, Turner M, Reynolds LF, et al. 1999. The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-κB pathways. Proc. Natl. Acad. Sci. USA 96:3035-40
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3035-3040
-
-
Costello, P.S.1
Walters, A.E.2
Mee, P.J.3
Turner, M.4
Reynolds, L.F.5
-
144
-
-
33846796315
-
Interaction of the Wiskott-Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cells
-
Badour K, McGavin MK, Zhang J, Freeman S, Vieira C, et al. 2007. Interaction of the Wiskott-Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cells. Proc. Natl. Acad. Sci. USA 104:1593-98
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 1593-1598
-
-
Badour, K.1
McGavin, M.K.2
Zhang, J.3
Freeman, S.4
Vieira, C.5
-
145
-
-
0035905308
-
The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis
-
McGavin MK, Badour K, Hardy LA, Kubiseski TJ, Zhang J, Siminovitch KA. 2001. The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis. J. Exp. Med. 194:1777-87
-
(2001)
J. Exp. Med
, vol.194
, pp. 1777-1787
-
-
McGavin, M.K.1
Badour, K.2
Hardy, L.A.3
Kubiseski, T.J.4
Zhang, J.5
Siminovitch, K.A.6
-
146
-
-
0842346270
-
Do phosphoinositide 3-kinases direct lymphocyte navigation?
-
Ward SG. 2004. Do phosphoinositide 3-kinases direct lymphocyte navigation? Trends Immunol. 25:67-74
-
(2004)
Trends Immunol
, vol.25
, pp. 67-74
-
-
Ward, S.G.1
-
147
-
-
3042642085
-
Requirement for Tec kinases in chemokine-induced migration and activation of Cdc42 and Rac
-
Takesono A, Horai R, Mandai M, Dombroski D, Schwartzberg PL. 2004. Requirement for Tec kinases in chemokine-induced migration and activation of Cdc42 and Rac. Curr. Biol. 14:917-22
-
(2004)
Curr. Biol
, vol.14
, pp. 917-922
-
-
Takesono, A.1
Horai, R.2
Mandai, M.3
Dombroski, D.4
Schwartzberg, P.L.5
-
148
-
-
28544448740
-
Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival
-
Liu E, Sinha S, Williams C, Cyrille M, Heller E, et al. 2005. Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival. Mol. Cell. Biol. 25:11145-55
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 11145-11155
-
-
Liu, E.1
Sinha, S.2
Williams, C.3
Cyrille, M.4
Heller, E.5
-
149
-
-
17044427681
-
Control of lymphocyte shape and the chemotactic response by the GTP exchange factor Vav
-
Vicente-Manzanares M, Cruz-Adalia A, Martin-Cofreces NB, Cabrero JR, Dosil M, et al. 2005. Control of lymphocyte shape and the chemotactic response by the GTP exchange factor Vav. Blood 105:3026-34
-
(2005)
Blood
, vol.105
, pp. 3026-3034
-
-
Vicente-Manzanares, M.1
Cruz-Adalia, A.2
Martin-Cofreces, N.B.3
Cabrero, J.R.4
Dosil, M.5
-
150
-
-
33750335844
-
CrkL plays a role in SDF-1-induced activation of the Raf-1/MEK/Erk pathway through Ras and Rac to mediate chemotactic signaling in hematopoietic cells
-
Arai A, Aoki M, Weihua Y, Jin A, Miura O. 2006. CrkL plays a role in SDF-1-induced activation of the Raf-1/MEK/Erk pathway through Ras and Rac to mediate chemotactic signaling in hematopoietic cells. Cell. Signal. 18:2162-71
-
(2006)
Cell. Signal
, vol.18
, pp. 2162-2171
-
-
Arai, A.1
Aoki, M.2
Weihua, Y.3
Jin, A.4
Miura, O.5
-
151
-
-
0036142414
-
Stromal cell-derived factor 1α activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis
-
Nishita M, Aizawa H, Mizuno K. 2002. Stromal cell-derived factor 1α activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis. Mol. Cell. Biol. 22:774-83
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 774-783
-
-
Nishita, M.1
Aizawa, H.2
Mizuno, K.3
-
152
-
-
0036136257
-
A role for the Rho-p 160 Rho coiled-coil kinase axis in the chemokine stromal cell-derived factor-1α-induced lymphocyte actomyosin and microtubular organization and chemotaxis
-
Vicente-Manzanares M, Cabrero JR, Rey M, Perez-Martinez M, Ursa A, et al. 2002. A role for the Rho-p 160 Rho coiled-coil kinase axis in the chemokine stromal cell-derived factor-1α-induced lymphocyte actomyosin and microtubular organization and chemotaxis. J. Immunol. 168:400-10
-
(2002)
J. Immunol
, vol.168
, pp. 400-410
-
-
Vicente-Manzanares, M.1
Cabrero, J.R.2
Rey, M.3
Perez-Martinez, M.4
Ursa, A.5
-
153
-
-
0035989343
-
Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in TH1 responses
-
Croker BA, Handman E, Hayball JD, Baldwin TM, Voigt V, et al. 2002. Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in TH1 responses. Immunol. Cell Biol. 80:231-40
-
(2002)
Immunol. Cell Biol
, vol.80
, pp. 231-240
-
-
Croker, B.A.1
Handman, E.2
Hayball, J.D.3
Baldwin, T.M.4
Voigt, V.5
-
154
-
-
17944375813
-
Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration
-
Fukui Y, Hashimoto O, Sanui T, Oono T, Koga H, et al. 2001. Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration. Nature 412:826-31
-
(2001)
Nature
, vol.412
, pp. 826-831
-
-
Fukui, Y.1
Hashimoto, O.2
Sanui, T.3
Oono, T.4
Koga, H.5
-
155
-
-
33748304311
-
DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration
-
Shulman Z, Pasvolsky R, Woolf E, Grabovsky V, Feigelson SW, et al. 2006. DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration. Blood 108:2150-58
-
(2006)
Blood
, vol.108
, pp. 2150-2158
-
-
Shulman, Z.1
Pasvolsky, R.2
Woolf, E.3
Grabovsky, V.4
Feigelson, S.W.5
-
156
-
-
33947411398
-
A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress
-
Nombela-Arrieta C, Mempel TR, Soriano SF, Mazo I, Wymann MP, et al. 2007. A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress. J. Exp. Med. 204:497-510
-
(2007)
J. Exp. Med
, vol.204
, pp. 497-510
-
-
Nombela-Arrieta, C.1
Mempel, T.R.2
Soriano, S.F.3
Mazo, I.4
Wymann, M.P.5
-
157
-
-
4444335344
-
Differential requirements for DOCK2 and phosphoinositide-3-kinase γ during T and B lymphocyte homing
-
Nombela-Arrieta C, Lacalle RA, Montoya MC, Kunisaki Y, Megias D, et al. 2004. Differential requirements for DOCK2 and phosphoinositide-3-kinase γ during T and B lymphocyte homing. Immunity 21:429-41
-
(2004)
Immunity
, vol.21
, pp. 429-441
-
-
Nombela-Arrieta, C.1
Lacalle, R.A.2
Montoya, M.C.3
Kunisaki, Y.4
Megias, D.5
-
158
-
-
27544502276
-
Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration
-
Nishita M, Tomizawa C, Yamamoto M, Horita Y, Ohashi K, Mizuno K. 2005. Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration. J. Cell Biol. 171:349-59
-
(2005)
J. Cell Biol
, vol.171
, pp. 349-359
-
-
Nishita, M.1
Tomizawa, C.2
Yamamoto, M.3
Horita, Y.4
Ohashi, K.5
Mizuno, K.6
-
159
-
-
33847338043
-
Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization
-
Li J, Brieher WM, Scimone ML, Kang SJ, Zhu H, et al. 2007. Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization. Nat. Cell Biol. 9:276-86
-
(2007)
Nat. Cell Biol
, vol.9
, pp. 276-286
-
-
Li, J.1
Brieher, W.M.2
Scimone, M.L.3
Kang, S.J.4
Zhu, H.5
-
160
-
-
33747106194
-
Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis
-
Foger N, Rangell L, Danilenko DM, Chan AC. 2006. Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis. Science 313:839-42
-
(2006)
Science
, vol.313
, pp. 839-842
-
-
Foger, N.1
Rangell, L.2
Danilenko, D.M.3
Chan, A.C.4
-
161
-
-
33847420825
-
Coronin IB coordinates Arp2/3 complex and cofilin activities at the leading edge
-
Cai L, Marshall TW, Uetrecht AC, Schafer DA, Bear JE. 2007. Coronin IB coordinates Arp2/3 complex and cofilin activities at the leading edge. Cell 128:915-29
-
(2007)
Cell
, vol.128
, pp. 915-929
-
-
Cai, L.1
Marshall, T.W.2
Uetrecht, A.C.3
Schafer, D.A.4
Bear, J.E.5
-
162
-
-
0037377169
-
Inhibition of actin polymerization enhances commitment to and execution of apoptosis induced by withdrawal of trophic support
-
Celeste Morley S, Sun GP, Bierer BE. 2003. Inhibition of actin polymerization enhances commitment to and execution of apoptosis induced by withdrawal of trophic support. J. Cell. Biochem. 88:1066-76
-
(2003)
J. Cell. Biochem
, vol.88
, pp. 1066-1076
-
-
Celeste Morley, S.1
Sun, G.P.2
Bierer, B.E.3
-
163
-
-
0036133127
-
Molecular ordering of the initial signaling events of CD95
-
Algeciras-Schimnich A, Shen L, Barnhart BC, Murmann AE, Burkhardt JK, Peter ME. 2002. Molecular ordering of the initial signaling events of CD95. Mol. Cell. Biol. 22:207-20
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 207-220
-
-
Algeciras-Schimnich, A.1
Shen, L.2
Barnhart, B.C.3
Murmann, A.E.4
Burkhardt, J.K.5
Peter, M.E.6
-
164
-
-
0038198615
-
Actin dependent CD95 internalization is specific for Type I cells
-
Algeciras-Schimnich A, Peter ME. 2003. Actin dependent CD95 internalization is specific for Type I cells. FEBS Lett. 546:185-88
-
(2003)
FEBS Lett
, vol.546
, pp. 185-188
-
-
Algeciras-Schimnich, A.1
Peter, M.E.2
-
165
-
-
33846192430
-
Palmitoylation is required for efficient Fas cell death signaling
-
Chakrabandhu K, Herincs Z, Huault S, Dost B, Peng L, et al. 2007. Palmitoylation is required for efficient Fas cell death signaling. EMBO J. 26:209-20
-
(2007)
EMBO J
, vol.26
, pp. 209-220
-
-
Chakrabandhu, K.1
Herincs, Z.2
Huault, S.3
Dost, B.4
Peng, L.5
-
166
-
-
12144288884
-
Association of a four-amino acid residue insertion polymorphism of the HS1 gene with systemic lupus erythematosus: Molecular and functional analysis
-
Otsuka J, Horiuchi T, Yoshizawa S, Tsukamoto H, Sawabe T, et al. 2004. Association of a four-amino acid residue insertion polymorphism of the HS1 gene with systemic lupus erythematosus: molecular and functional analysis. Arthritis Rheum. 50:871-81
-
(2004)
Arthritis Rheum
, vol.50
, pp. 871-881
-
-
Otsuka, J.1
Horiuchi, T.2
Yoshizawa, S.3
Tsukamoto, H.4
Sawabe, T.5
-
167
-
-
0642309014
-
Aberrant HS1 molecule in a patient with systemic lupus erythematosus
-
Sawabe T, Horiuchi T, Koga R, Tsukamoto H, Kojima T, et al. 2003. Aberrant HS1 molecule in a patient with systemic lupus erythematosus. Genes Immun. 4:122-31
-
(2003)
Genes Immun
, vol.4
, pp. 122-131
-
-
Sawabe, T.1
Horiuchi, T.2
Koga, R.3
Tsukamoto, H.4
Kojima, T.5
-
168
-
-
33846536952
-
Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus
-
Li Y, Harada T, Juang YT, Kyttaris VC, Wang Y, et al. 2007. Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus. J. Immunol. 178:1938-47
-
(2007)
J. Immunol
, vol.178
, pp. 1938-1947
-
-
Li, Y.1
Harada, T.2
Juang, Y.T.3
Kyttaris, V.C.4
Wang, Y.5
-
169
-
-
33746292619
-
Interactions of human retroviruses with the host cell cytoskeleton
-
Fackler OT, Krausslich HG. 2006. Interactions of human retroviruses with the host cell cytoskeleton. Curr. Opin. Microbiol. 9:409-15
-
(2006)
Curr. Opin. Microbiol
, vol.9
, pp. 409-415
-
-
Fackler, O.T.1
Krausslich, H.G.2
|