메뉴 건너뛰기




Volumn 3, Issue 11, 2002, Pages 1082-1089

Sustained and dynamic inositol lipid metabolism inside and outside the immonological synapse

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; INOSITOL; LIPID; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE;

EID: 0036853106     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni848     Document Type: Article
Times cited : (184)

References (50)
  • 1
    • 0035367805 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinases in T lymphocyte activation
    • Ward, S. G. & Cantrell, D. A. Phosphoinositide 3-kinases in T lymphocyte activation. Curr. Opin. Immunol. 13, 332-338 (2001).
    • (2001) Curr. Opin. Immunol , vol.13 , pp. 332-338
    • Ward, S.G.1    Cantrell, D.A.2
  • 2
    • 0035020950 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase signalling pathways
    • Cantrell, D. A. Phosphoinositide 3-kinase signalling pathways. J. Cell Sci. 114, 1439-1445 (2001).
    • (2001) J. Cell Sci , vol.114 , pp. 1439-1445
    • Cantrell, D.A.1
  • 3
    • 0036200194 scopus 로고    scopus 로고
    • Protein kinase B (Akt) regulation and function in T lymphocytes
    • Cantrell, D. Protein kinase B (Akt) regulation and function in T lymphocytes. Semin. Immunol. 14, 19-26 (2002).
    • (2002) Semin. Immunol , vol.14 , pp. 19-26
    • Cantrell, D.1
  • 4
    • 0034653608 scopus 로고    scopus 로고
    • The P13K-PDK1 connection: More than just a road to PKB
    • Vanhaesebroeck, B. & Alessi, D. R. The P13K-PDK1 connection: more than just a road to PKB. Biochem. J. 346, 561-576 (2000).
    • (2000) Biochem. J , vol.346 , pp. 561-576
    • Vanhaesebroeck, B.1    Alessi, D.R.2
  • 5
    • 0036199607 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase in immunological systems
    • Fruman, D. A. & Cantley, L. C. Phosphoinositide 3-kinase in immunological systems. Semin. Immunol. 14, 7-18 (2002).
    • (2002) Semin. Immunol , vol.14 , pp. 7-18
    • Fruman, D.A.1    Cantley, L.C.2
  • 6
    • 0030293886 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways
    • Reif, K., Nobes, C. D., Thomas, G., Hall, A. & Cantrell, D. A. Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways. Curr. Biol. 6, 1445-1455 (1996).
    • (1996) Curr. Biol , vol.6 , pp. 1445-1455
    • Reif, K.1    Nobes, C.D.2    Thomas, G.3    Hall, A.4    Cantrell, D.A.5
  • 7
    • 0037047590 scopus 로고    scopus 로고
    • Impaired B and T cell antigen receptor signaling in p110δ P13-kinase mutant mice
    • Okkenhaug, K. et al. Impaired B and T cell antigen receptor signaling in p110δ P13-kinase mutant mice. Science 297, 1031-1034 (2002).
    • (2002) Science , vol.297 , pp. 1031-1034
    • Okkenhaug, K.1
  • 9
    • 0035892899 scopus 로고    scopus 로고
    • IL-7 enhances the survival and maintains the size of naive T cells
    • Rathmell, J. C., Farkash, E. A., Gao, W. & Thompson, C. B. IL-7 enhances the survival and maintains the size of naive T cells. J. Immunol. 167, 6869-6876 (2001).
    • (2001) J. Immunol , vol.167 , pp. 6869-6876
    • Rathmell, J.C.1    Farkash, E.A.2    Gao, W.3    Thompson, C.B.4
  • 10
    • 0036069699 scopus 로고    scopus 로고
    • The CD28 signaling pathway regulates glucose metabolism
    • Frauwirth, K. A. et al. The CD28 signaling pathway regulates glucose metabolism. Immunity 16, 769-777 (2002).
    • (2002) Immunity , vol.16 , pp. 769-777
    • Frauwirth, K.A.1
  • 11
    • 0036629251 scopus 로고    scopus 로고
    • Cell cycle and death control: Long live Forkheads
    • Burgering, B. M. & Kops, G. J. Cell cycle and death control: long live Forkheads. Trends Biochem. Sci. 27, 352-360 (2002).
    • (2002) Trends Biochem. Sci , vol.27 , pp. 352-360
    • Burgering, B.M.1    Kops, G.J.2
  • 12
    • 0031433335 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase controls E2F transcriptional activity in response to interleukin-2
    • Brennan, P. et al. Phosphatidylinositol 3-kinase controls E2F transcriptional activity in response to interleukin-2. Immunity 7, 679-689 (1997).
    • (1997) Immunity , vol.7 , pp. 679-689
    • Brennan, P.1
  • 14
    • 0026502874 scopus 로고
    • Regulation of D-3 phosphoinositides during T cell activation via the T cell antigen receptor/CD3 complex and CD2 antigens
    • Ward, S. G., Ley, S. C., MacPhee, C. & Cantrell, D. A. Regulation of D-3 phosphoinositides during T cell activation via the T cell antigen receptor/CD3 complex and CD2 antigens. Eur. J. Immunol. 22, 45-49 (1992).
    • (1992) Eur. J. Immunol , vol.22 , pp. 45-49
    • Ward, S.G.1    Ley, S.C.2    MacPhee, C.3    Cantrell, D.A.4
  • 15
    • 0034550280 scopus 로고    scopus 로고
    • The T cell antigen receptor activates phosphatidylinositol 3-kinase-regulated serine kinases protein kinase B and ribosomal S6 kinase 1
    • Lafont, V., Astoul, E., Laurence, A., Liautard, J. & Cantrell, D. The T cell antigen receptor activates phosphatidylinositol 3-kinase-regulated serine kinases protein kinase B and ribosomal S6 kinase 1. FEBS Lett. 486, 38-42 (2000).
    • (2000) FEBS Lett , vol.486 , pp. 38-42
    • Lafont, V.1    Astoul, E.2    Laurence, A.3    Liautard, J.4    Cantrell, D.5
  • 16
    • 0031936042 scopus 로고    scopus 로고
    • + T cells: Compulsory cytoskeletal alterations for the triggering of an intracellular calcium response
    • + T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response. Eur. J. Immunol. 28, 716-729 (1998).
    • (1998) Eur. J. Immunol , vol.28 , pp. 716-729
    • Delon, J.1    Bercovici, N.2    Liblau, R.3    Trautmann, A.4
  • 18
    • 0026606454 scopus 로고
    • Imaging early steps of human T cell activation by antigen-presenting cells
    • Donnadieu, E. et al. Imaging early steps of human T cell activation by antigen-presenting cells. J. Immunol. 148, 2643-2653 (1992).
    • (1992) J. Immunol , vol.148 , pp. 2643-2653
    • Donnadieu, E.1
  • 19
    • 0034769286 scopus 로고    scopus 로고
    • Functional antigen-independent synapses formed between T cells and dendritic cells
    • Revy, P., Sospedra, M., Barbour, B. & Trautmann, A. Functional antigen-independent synapses formed between T cells and dendritic cells. Nature Immunol. 2, 925-931 (2001).
    • (2001) Nature Immunol , vol.2 , pp. 925-931
    • Revy, P.1    Sospedra, M.2    Barbour, B.3    Trautmann, A.4
  • 20
    • 0037154747 scopus 로고    scopus 로고
    • T cell receptor signaling precedes immunological synapse formation
    • Lee, K. H. et al. T cell receptor signaling precedes immunological synapse formation. Science 295, 1539-1542 (2002).
    • (2002) Science , vol.295 , pp. 1539-1542
    • Lee, K.H.1
  • 21
    • 0034581533 scopus 로고    scopus 로고
    • Studies of signal transduction events using chimeras to green fluorescent protein
    • Meyer, T. & Oancea, E. Studies of signal transduction events using chimeras to green fluorescent protein. Meth. Enzymol. 327, 500-513 (2000).
    • (2000) Meth. Enzymol , vol.327 , pp. 500-513
    • Meyer, T.1    Oancea, E.2
  • 22
    • 0034644538 scopus 로고    scopus 로고
    • Translocation and reversible localization of signaling proteins: A dynamic future for signal transduction
    • Teruel, M. N. & Meyer, T. Translocation and reversible localization of signaling proteins: a dynamic future for signal transduction. Cell 103, 181-184 (2000).
    • (2000) Cell , vol.103 , pp. 181-184
    • Teruel, M.N.1    Meyer, T.2
  • 23
    • 0037040545 scopus 로고    scopus 로고
    • Parallel single-cell monitoring of receptor-triggered membrane translocation of a calcium-sensing protein module
    • Teruel, M. N. & Meyer, T. Parallel single-cell monitoring of receptor-triggered membrane translocation of a calcium-sensing protein module. Science 295, 1910-1912 (2002).
    • (2002) Science , vol.295 , pp. 1910-1912
    • Teruel, M.N.1    Meyer, T.2
  • 24
    • 0032855089 scopus 로고    scopus 로고
    • Dynamic re-distribution of protein kinase D (PKD) as revealed by a GFP-PKD fusion protein: Dissociation from PKD activation
    • Matthews, S., Iglesias, T., Cantrell, D. & Rozengurt, E. Dynamic re-distribution of protein kinase D (PKD) as revealed by a GFP-PKD fusion protein: dissociation from PKD activation. FEBS Lett 457, 515-521 (1999).
    • (1999) FEBS Lett , vol.457 , pp. 515-521
    • Matthews, S.1    Iglesias, T.2    Cantrell, D.3    Rozengurt, E.4
  • 25
    • 0034659737 scopus 로고    scopus 로고
    • Spatial and temporal regulation of protein kinase D (PKD)
    • Matthews, S. A., Iglesias, T., Rozengurt, E. & Cantrell, D. Spatial and temporal regulation of protein kinase D (PKD). EMBO J. 19, 2935-2945 (2000).
    • (2000) EMBO J , vol.19 , pp. 2935-2945
    • Matthews, S.A.1    Iglesias, T.2    Rozengurt, E.3    Cantrell, D.4
  • 26
    • 0034638836 scopus 로고    scopus 로고
    • Spatial sensing in fibroblasts mediated by 3′ phosphoinositides
    • Haugh, J. M., Codazzi, F., Teruel, M. & Meyer, T. Spatial sensing in fibroblasts mediated by 3′ phosphoinositides. J. Cell Biol. 151, 1269-1280 (2000).
    • (2000) J. Cell Biol , vol.151 , pp. 1269-1280
    • Haugh, J.M.1    Codazzi, F.2    Teruel, M.3    Meyer, T.4
  • 27
    • 0035954430 scopus 로고    scopus 로고
    • Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fcγ receptor-mediated phagocytosis
    • Marshall, J. G. et al. Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fcγ receptor-mediated phagocytosis. J. Cell Biol. 153, 1369-1380 (2001).
    • (2001) J. Cell Biol , vol.153 , pp. 1369-1380
    • Marshall, J.G.1
  • 28
    • 0033612540 scopus 로고    scopus 로고
    • The dynamics of protein kinase B regulation during B cell antigen receptor engagement
    • Astoul, E., Watton, S. & Cantrell, D. The dynamics of protein kinase B regulation during B cell antigen receptor engagement. J. Cell Biol. 145, 1511-1520 (1999).
    • (1999) J. Cell Biol , vol.145 , pp. 1511-1520
    • Astoul, E.1    Watton, S.2    Cantrell, D.3
  • 29
    • 0033594403 scopus 로고    scopus 로고
    • Akt/PKB localisation and 3′ phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction
    • Watton, S. J. & Downward, J. Akt/PKB localisation and 3′ phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction. Curr. Biol. 9, 433-436 (1999).
    • (1999) Curr. Biol , vol.9 , pp. 433-436
    • Watton, S.J.1    Downward, J.2
  • 30
    • 0033560747 scopus 로고    scopus 로고
    • Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium
    • Meili, R. et al. Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO J. 18, 2092-2105 (1999).
    • (1999) EMBO J , vol.18 , pp. 2092-2105
    • Meili, R.1
  • 31
    • 0034232037 scopus 로고    scopus 로고
    • The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling
    • Dustin, M. L. & Cooper, J. A. The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. Nature Immunol. 1, 23-29 (2000).
    • (2000) Nature Immunol , vol.1 , pp. 23-29
    • Dustin, M.L.1    Cooper, J.A.2
  • 32
    • 0033538574 scopus 로고    scopus 로고
    • The immunological synapse: A molecular machine controlling T cell activation
    • Grakoui, A. et al. The immunological synapse: a molecular machine controlling T cell activation. Science 285, 221-227 (1999).
    • (1999) Science , vol.285 , pp. 221-227
    • Grakoui, A.1
  • 33
    • 0035059418 scopus 로고    scopus 로고
    • The immunological synapse
    • Bromley, S. K. et al. The immunological synapse. Annu. Rev. Immunol. 19, 375-396 (2001).
    • (2001) Annu. Rev. Immunol , vol.19 , pp. 375-396
    • Bromley, S.K.1
  • 34
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • Monks, C. R., Freiberg, B. A., Kupfer H., Sciaky, N. & Kupfer, A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395, 82-86 (1998).
    • (1998) Nature , vol.395 , pp. 82-86
    • Monks, C.R.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 35
    • 0035940426 scopus 로고    scopus 로고
    • + T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells
    • + T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells. Proc. Natl. Acad. Sci. USA 98, 12624-12629 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12624-12629
    • Potter, T.A.1    Grebe, K.2    Freiberg, B.3    Kupfer, A.4
  • 36
    • 0036359608 scopus 로고    scopus 로고
    • Transgenic analysis of thymocyte signal transduction
    • Cantrell, D. A. Transgenic analysis of thymocyte signal transduction. Nature Rev. Immunol. 2, 20-27 (2002).
    • (2002) Nature Rev. Immunol , vol.2 , pp. 20-27
    • Cantrell, D.A.1
  • 37
    • 0035876932 scopus 로고    scopus 로고
    • + lymphocyte rolling in inflamed venules
    • + lymphocyte rolling in inflamed venules. J. Immunol. 166, 7520-7526 (2001).
    • (2001) J. Immunol , vol.166 , pp. 7520-7526
    • Singbartl, K.1
  • 38
    • 0027368922 scopus 로고
    • T cell deletion follows chronic antigen specific T cell activation in vivo
    • Mamalaki, C. et al. T cell deletion follows chronic antigen specific T cell activation in vivo. Int. Immunol. 5, 1285-1292 (1993).
    • (1993) Int. Immunol , vol.5 , pp. 1285-1292
    • Mamalaki, C.1
  • 39
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • Pircher, H., Burki, K., Lang, R., Hengartner, H. & Zinkernagel, R. M. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 342, 559-561 (1989).
    • (1989) Nature , vol.342 , pp. 559-561
    • Pircher, H.1    Burki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 40
    • 0033980716 scopus 로고    scopus 로고
    • From synapses to immunological memory: The role of sustained T cell stimulation
    • Lanzavecchia, A. & Sallusto, F. From synapses to immunological memory: The role of sustained T cell stimulation. Curr. Opin. Immunol. 12, 92-98 (2000).
    • (2000) Curr. Opin. Immunol , vol.12 , pp. 92-98
    • Lanzavecchia, A.1    Sallusto, F.2
  • 41
    • 0030914290 scopus 로고    scopus 로고
    • Understanding the mechanisms of sustained signaling and T cell activation
    • Lanzavecchia, A. Understanding the mechanisms of sustained signaling and T cell activation. J. Exp. Med. 185, 1717-1719 (1997).
    • (1997) J. Exp. Med , vol.185 , pp. 1717-1719
    • Lanzavecchia, A.1
  • 42
    • 0031884839 scopus 로고    scopus 로고
    • The duration of antigenic stimulation determines the fate of naive and effector T cells
    • Lezzi, G., Karjalainen, K. & Lanzavecchia, A. The duration of antigenic stimulation determines the fate of naive and effector T cells. Immunity 8, 89-95 (1998).
    • (1998) Immunity , vol.8 , pp. 89-95
    • Lezzi, G.1    Karjalainen, K.2    Lanzavecchia, A.3
  • 43
    • 0035451761 scopus 로고    scopus 로고
    • PI 3-K and T-cell activation: Limitations of T-leukemic cell lines as signaling models
    • Astoul, E., Edmunds, C., Cantrell, D. A. & Ward, S. G. PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models. Trends Immunol. 22, 490-496 (2001).
    • (2001) Trends Immunol , vol.22 , pp. 490-496
    • Astoul, E.1    Edmunds, C.2    Cantrell, D.A.3    Ward, S.G.4
  • 44
    • 0035655587 scopus 로고    scopus 로고
    • The immunological synapse of CTL contains a secretory domain and membrane bridges
    • Stinchcombe, J. C., Bossi, G., Booth, S. & Griffiths, G. M. The immunological synapse of CTL contains a secretory domain and membrane bridges. Immunity 15, 751-761 (2001).
    • (2001) Immunity , vol.15 , pp. 751-761
    • Stinchcombe, J.C.1    Bossi, G.2    Booth, S.3    Griffiths, G.M.4
  • 45
    • 0037154745 scopus 로고    scopus 로고
    • Immunology. The immunological synapse-a multitasking system
    • van Der Merwe, P. A. & Davis, S. J. Immunology. The immunological synapse-a multitasking system. Science 295, 1479-1480 (2002).
    • (2002) Science , vol.295 , pp. 1479-1480
    • Van Der Merwe, P.A.1    Davis, S.J.2
  • 46
    • 0035336165 scopus 로고    scopus 로고
    • LFA-1-mediated costimulation of CD8+ T cell proliferation requires phosphatidylinositol 3-kinase activity
    • Ni, H. T., Deeths, M. J. & Mescher, M. F. LFA-1-mediated costimulation of CD8+ T cell proliferation requires phosphatidylinositol 3-kinase activity. J. Immunol. 166, 6523-6529 (2001).
    • (2001) J. Immunol , vol.166 , pp. 6523-6529
    • Ni, H.T.1    Deeths, M.J.2    Mescher, M.F.3
  • 47
    • 0035652354 scopus 로고    scopus 로고
    • Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin
    • Delon, J., Kaibuchi, K. & Germain, R. N. Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin. Immunity 15, 691-701 (2001).
    • (2001) Immunity , vol.15 , pp. 691-701
    • Delon, J.1    Kaibuchi, K.2    Germain, R.N.3
  • 48
    • 0032534304 scopus 로고    scopus 로고
    • TCR signaling induces selective exclusion of CD43 from the T cell-antigen-presenting cell contact site
    • Sperling, A. I. et al. TCR signaling induces selective exclusion of CD43 from the T cell-antigen-presenting cell contact site. J. Immunol. 161, 6459-6462 (1998).
    • (1998) J. Immunol , vol.161 , pp. 6459-6462
    • Sperling, A.I.1
  • 49
    • 0035654721 scopus 로고    scopus 로고
    • The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation
    • Roumier, A. et al. The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation. Immunity 15, 715-728 (2001).
    • (2001) Immunity , vol.15 , pp. 715-728
    • Roumier, A.1
  • 50
    • 0029037960 scopus 로고
    • Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice
    • Zhumabekov, T., Corbella, P., Tolaini, M. & Kioussis, D. Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice. J. Immunol. Meth. 185, 133-140 (1995).
    • (1995) J. Immunol. Meth , vol.185 , pp. 133-140
    • Zhumabekov, T.1    Corbella, P.2    Tolaini, M.3    Kioussis, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.