Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome

Journal of Allergy and Clinical Immunology

Volumn 116, Issue 6, 2005, Pages 1364-1371

  Cianferoni, Antonella ^a,c   Massaad, Michel ^a,c   Feske, Stefan ^b,c   De La Fuente, Miguel A ^a,c   Gallego, Lola ^a,c   Ramesh, Narayanaswamy ^a,c   Geha, Raif S ^a,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b CENTER FOR BLOOD RESEARCH   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

c fos; c Jun; Erk; IL 2 gene regulation; Jnk; NF B; NF AT; WASP

Indexed keywords

ANTIBODY; CD28 ANTIGEN; CD3 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEAR FACTOR; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR NFAT; WISKOTT ALDRICH SYNDROME PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA BINDING; ENZYME SUBSTRATE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPHOSPHORYLATION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; WESTERN BLOTTING; WISKOTT ALDRICH SYNDROME;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; DNA; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INTERLEUKIN-2; MICE; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-JUN; RNA, MESSENGER; T-LYMPHOCYTES; TRANSCRIPTION FACTOR AP-1; WISKOTT-ALDRICH SYNDROME; WISKOTT-ALDRICH SYNDROME PROTEIN;

EID: 28444431954     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2005.09.006     Document Type: Article

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