Transforming growth factor-β regulates tubular epithelial-myofibroblast transdifferentiation in vitro

Kidney International

Volumn 56, Issue 4, 1999, Pages 1455-1467

  Fan, Jun Ming ^a,e   Yee Yung, N G ^b   Hill, Prudence A ^c   Nikolic Paterson, David J ^d   Mu, Wei ^a   Atkins, Robert C ^b   Lan, Hui Y ^c  

^a WEST CHINA UNIVERSITY OF MEDICAL SCIENCES   (China)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d MONASH UNIVERSITY   (Australia)

^e MONASH MEDICAL CENTRE   (Australia)

Author keywords

Collagen type 1; Fibrosis; TGF ; Transdifferentiation; Tubulointerstitial fibrosis; smooth muscle actin

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

ANIMAL TISSUE; CELL DIFFERENTIATION; CELL GROWTH; CELL POLARITY; CELL STRUCTURE; CONFERENCE PAPER; IN VITRO STUDY; KIDNEY FIBROSIS; KIDNEY TUBULE EPITHELIUM; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0032842887     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1999.00656.x     Document Type: Conference Paper

References (36)

1. EDDY A A: Molecular insights into renal interstitial fibrosis. J Am Soc Nephrol 7:2495-2508, 1996
2. CREELY JH, COMMERS PA, HARALSON MA: Synthesis of type III collagen by cultured kidney epithelial cells. Conned Tissue Res 18:107-122, 1988
3. CREELY JJ, DIMARI SJ, HOWE AM, HARALSON MA: Effects of transforming growth factor-beta on collagen synthesis by normal rat kidney epithelial cells. Am J Palhol 140:45-55, 1992
4. TANG Ww, VAN GY, Qi M: Myofibroblast and a, (III) collagen expression in experimental tubulointerstitial nephritis. Kidney Int 51:926-931, 1997
5. HOGEMANN B, GlLLESSEN A, BOCKER W, RAUTERBERG J, DO.MSCIIKE W: Myofibroblast-like cells produce mRNA for type I and III procollagens in chronic active hepatitis. Scanil J Gastroenterol 28:591-594, 1993
6. ZIIANG HY, GIIARAEE-KER.MANI M, ZIIANO K, KARMIOL S, PIIAN SU: Lung fibroblast alpha-smooth muscle actin expression and contractile phenotype in bleomycin-induced pulmonary fibrosis. Am J Pathol 148:527-537, 1996
7. ALPERS CE, HUDKINS KL, FLOEGE J, JOHNSON RJ: Human renal cortical interstitial cells with some features of smooth muscle cells participate in tubulointerstitial and crescentic glomerular injury. J Am Soc Nephrol 5:201-209, 1994
8. GOUMENOS DS, BROWN CB, SIIORTLAND J, EL NAIIAS AM: Myofibroblasts, predictors of progression of mesangial IgA nephropathy? Nephrol Dial Transplant 9:1418-1425, 1994
9. HEWITSON TD, BECKER GJ: Interstitial myofibroblasts in IgA glomerulonephritis. Am J Nephrol 15:111-117, 1995
10. ROBERTS IS, BURROWS C, SHANKS JH, YENNING M, MCWILLIAM LJ: Interstitial myofibroblasts: Predictors of progression in membranous nephropathy. J Clin Pallia! 50:123-127ri997
11. ESSAWY M, SOYLEMEZOGLU O, MUCHANETA-KUBARA EC, SlIORT-LAND J, BROWN CB, EL NAIIAS AM: Myofibroblasts and the progression of diabetic nephropathy. Nephrol Dial Transplant 12:4350, 1997
12. HEWITSON TD, Wu HL, BECKER GJ: Interstitial myofibroblasts in experimental renal infection and scarring. Am J Nephrol 15:411417, 1995
13. DIAMOND JR, VAN GH, DING G, ENGELMYER E: Myofibroblasts in experimental hydronephrosis. Am J Pathol 146:121-129, 1995
14. ZIIANG G, MOORIIEAD PJ, EL NAIIAS AM: Myofibroblasts and the progression of experimental glomerulonephritis. Exp Nephrol 3:308-318, 1995
15. DESMOULIERE A, GABBIANI G: Myofibroblast differentiation during fibrosis. Exp Nephrol 3:134-139, 1995
16. MASUR SK, DEWAL HS, DI.NII TT, ERENBURG I, PETRIDOU S: Myofibroblasts differentiate from fibroblasts when plated at low density. Proc Natl Acad Sci USA 93:4219-4223, 1996
17. TANG WW, ULICII TR, LACEY DL, HILL DC, Qi M, KAUFMAN SA, VAN GY, TARPLEY JE, YEE JS: Platelet-derived growth factorBB induces renal tubulointerstitial myofibroblast formation and tubulointerstitial fibrosis. Am J Pathol 148:1169-1180, 1996
18. STRUTZ F, OKADA H, Lo CW, DANOFFT, CARONE RL, TOMASZEWSKI JE, NEILSON EG: Identification and characterization of a fibroblast marker: FSP1. J Cell Dial 130:393-405, 1995
19. Nc YY, HUANG TP, YANG WC, CIIEN ZP, YANG AH, Mu W, NIKOLIC-PATERSON DJ, ATKINS RC, LAN HY: Evidence for tubular epithelial-myofibroblast transdiffercntiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats. Kidney Int 54:864-876, 1998
20. BORDER WA, NOBLE NA: TGF-beta in kidney fibrosis: A target for gene therapy. Kidney Int 51:1388-1396, 1997
21. ISAKA Y, FUJIWARA Y, UEDA N, KANEDA Y, KAMADA T, IMAI E: Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney. J Clin Invest 92:2597-2601, 1993
22. MIETTINEN PJ, EBNER R, LOPEZ AR, DERYNCK R: TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors. J Cell Dial 127:2021-2036, 1994
23. Pons JD, DAGLE JM, WALDER JA, WEEKS DL, RUNYAN RB: Epithelial-mesenchymal transformation of embryonic cardiac endothelial cells is inhibited by a modified antiscnse oligodeoxynuclcotide to transforming growth factor beta 3. Proc NatlAcad Sci USA 88:1516-1520, 1991
24. OKADA H, DANOFF TM, KALLURI R, NEILSON EG: Early role of Fspl in epithelial-mesenchymal transformation. Am J Pliysiol 273:F563-F574, 1997
25. SUZUKI E, HIRATA Y, HAYAKAWA H, OMATA M, KANGAWA K, MiNAMINO N, MATSUO H: Evidence for C-type natriuretic pcptide production in the rat kidney. Biochem Biophys Res Commun 192:532-538, 1993
26. WALKER C, EVERITT J, FREED JJ, KNUDSON AG JR, WIIITELEY LO: Altered expression of transforming growth factor-alpha in hereditary rat renal cell carcinoma. Cancer Res 51:2973-2978, 1991
27. HILL PA, LAN HY, NIKOLIC-PATERSON DJ, ATKINS RC: ICAM-1 directs migration and localization of interstitial leukocytes in experimental glomerulonephritis. Kidney Int 45:32-42, 1994
28. McHuGii KM, LESSARD JL: The nucleotide sequence of a rat vascular smooth muscle alpha-actin cDNA. Nucleic Acid Res 16:4167, 1988
29. HATTORI M, NIKOLIC-PATERSON DJ, LAN HY, KAWAGUCIII H, ITO K, ATKINS RC: Up-regulation of ICAM-1 and VCAM-1 expression during macrophage recruitment in lipid-induced glomerular injury in ExHC rats. Nephrology 1:221-232, 1995
30. NIKOLIC-PATERSON DJ, JUN Z,TESCII GH, LAN HY, FOTI R, ATKINS RC: De novo CD44 expression by proliferating mesangial cells in anti-Thy-1 nephritis in the rat. J Am Soc Nephrol 7:1006-1014, 1996
31. LAN HY, HUTCHINSON P, TESCII GH, Mu W, ATKINS RC: A novel method of microwave treatment for detection of cytoplasmic and nuclear antigens by flow cytomctry. J Immunol Methods 190:1-10, 1996
32. HUMES HD, BEALS TF, CIESLINSKI DA, SANCIIEZ IO, PAGE TP: Effects of transforming growth factor-beta, transforming growth factor-alpha, and other growth factors on renal proximal tubule cells. Lab Invest 64:538-545, 1991
33. HUMES HD, NAKAMURA T, CIESLINSKI DA, MILLER D, EMMONS RV, BORDER WA: Role of proteoglycans and cytoskeleton in the effects of TGF-beta 1 on renal proximal tubule cells. Kidney Int 43:575-584, 1993
34. HAY ED, ZUK A: Transformations between epithelium and mesenchyme: Normal, pathological, and experimentally induced. Am J Kidney Dis 26:678-690, 1995
35. ZUK A, HAY ED: Expression of beta 1 integrins changes during transformation of avian lens epithelium to mesenchyme in collagen gels. Dev Dyn 201:378-393, 1994
36. ZUK A, MATLIN KS, HAY ED: Type I collagen gel induces MadinDarby canine kidney cells to become fusiform in shape and lose apical-basal polarity. J Cell Biol 108:903-919, 1989