-
1
-
-
0030026679
-
Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase
-
Hannigan G.E., Leung-Hagesteijn C., Fitz-Gibbon L., Coppolino M.G., Radeva G., Filmus J., Bell J.C., Dedhar S. Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase. Nature. 379:1996;91-96.
-
(1996)
Nature
, vol.379
, pp. 91-96
-
-
Hannigan, G.E.1
Leung-Hagesteijn, C.2
Fitz-Gibbon, L.3
Coppolino, M.G.4
Radeva, G.5
Filmus, J.6
Bell, J.C.7
Dedhar, S.8
-
2
-
-
0030786162
-
Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase
-
Li F., Liu J., Mayne R., Wu C. Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase. Biochim. Biophys. Acta. 1358:1997;215-220.
-
(1997)
Biochim. Biophys. Acta
, vol.1358
, pp. 215-220
-
-
Li, F.1
Liu, J.2
Mayne, R.3
Wu, C.4
-
3
-
-
0033020670
-
The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells
-
Tu Y., Li F., Goicoechea S., Wu C. The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells. Mol. Cell. Biol. 19:1999;2425-2434.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2425-2434
-
-
Tu, Y.1
Li, F.2
Goicoechea, S.3
Wu, C.4
-
4
-
-
0032530482
-
Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
-
Delcommenne M., Tan C., Gray V., Rue L., Woodgett J., Dedhar S. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase. Proc. Natl. Acad. Sci. U. S. A. 95:1998;11211-11216.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 11211-11216
-
-
Delcommenne, M.1
Tan, C.2
Gray, V.3
Rue, L.4
Woodgett, J.5
Dedhar, S.6
-
5
-
-
0033378656
-
Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats
-
Li F., Zhang Y., Wu C. Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats. J. Cell. Sci. 112(Pt 24):1999;4589-4599.
-
(1999)
J. Cell. Sci.
, vol.112
, Issue.PT 24
, pp. 4589-4599
-
-
Li, F.1
Zhang, Y.2
Wu, C.3
-
6
-
-
0035341207
-
Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1
-
Leung-Hagesteijn C., Mahendra A., Naruszewicz I., Hannigan G.E. Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1. EMBO J. 20:2001;2160-2170.
-
(2001)
EMBO J.
, vol.20
, pp. 2160-2170
-
-
Leung-Hagesteijn, C.1
Mahendra, A.2
Naruszewicz, I.3
Hannigan, G.E.4
-
7
-
-
0033144540
-
Integrin-linked kinase and associated proteins
-
Huang Y., Wu C. Integrin-linked kinase and associated proteins. Int. J. Mol. Med. 3:1999;563-572.
-
(1999)
Int. J. Mol. Med.
, vol.3
, pp. 563-572
-
-
Huang, Y.1
Wu, C.2
-
8
-
-
0035969233
-
Integrin-linked kinase (ILK) and its interactors: A new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes
-
Wu C., Dedhar S. Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes. J. Cell Biol. 155:2001;505-510.
-
(2001)
J. Cell Biol.
, vol.155
, pp. 505-510
-
-
Wu, C.1
Dedhar, S.2
-
9
-
-
0035972170
-
A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading
-
Tu Y., Huang Y., Zhang Y., Hua Y., Wu C. A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading. J. Cell Biol. 153:2001;585-598.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 585-598
-
-
Tu, Y.1
Huang, Y.2
Zhang, Y.3
Hua, Y.4
Wu, C.5
-
10
-
-
0035844879
-
A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction
-
Yamaji S., Suzuki A., Sugiyama Y., Koide Y., Yoshida M., Kanamori H., Mohri H., Ohno S., Ishigatsubo Y. A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction. J. Cell Biol. 153:2001;1251-1264.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1251-1264
-
-
Yamaji, S.1
Suzuki, A.2
Sugiyama, Y.3
Koide, Y.4
Yoshida, M.5
Kanamori, H.6
Mohri, H.7
Ohno, S.8
Ishigatsubo, Y.9
-
11
-
-
0035968234
-
Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions
-
Nikolopoulos S.N., Turner C.E. Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions. J. Biol. Chem. 276:2001;23499-23505.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 23499-23505
-
-
Nikolopoulos, S.N.1
Turner, C.E.2
-
12
-
-
0344012484
-
Integration of cell attachment, cytoskeletal localization and signaling by Integrin-Linked Kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN
-
Attwell S., Mills J., Troussard A., Wu C., Dedhar S. Integration of cell attachment, cytoskeletal localization and signaling by Integrin-Linked Kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN. Mol. Biol. Cell. 14:2004;4813-4825.
-
(2004)
Mol. Biol. Cell
, vol.14
, pp. 4813-4825
-
-
Attwell, S.1
Mills, J.2
Troussard, A.3
Wu, C.4
Dedhar, S.5
-
13
-
-
0034104592
-
Cell-substrate interactions and signaling through ILK
-
Dedhar S. Cell-substrate interactions and signaling through ILK. Curr. Opin. Cell Biol. 12:2000;250-256.
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 250-256
-
-
Dedhar, S.1
-
14
-
-
0031962084
-
Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity
-
Wu C., Keightley S.Y., Leung-Hagesteijn C., Radeva G., Coppolino M., Goicoechea S., McDonald J.A., Dedhar S. Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity. J. Biol. Chem. 273:1998;528-536.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 528-536
-
-
Wu, C.1
Keightley, S.Y.2
Leung-Hagesteijn, C.3
Radeva, G.4
Coppolino, M.5
Goicoechea, S.6
McDonald, J.A.7
Dedhar, S.8
-
15
-
-
0035900740
-
Integrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells
-
Ishii T., Satoh E., Nishimura M. Integrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells. J. Biol. Chem. 276:2001;42994-43003.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42994-43003
-
-
Ishii, T.1
Satoh, E.2
Nishimura, M.3
-
16
-
-
0034724443
-
Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells
-
Persad S., Attwell S., Gray V., Delcommenne M., Troussard A., Sanghera J., Dedhar S. Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells. Proc. Natl. Acad. Sci. U. S. A. 97:2000;3207-3212.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 3207-3212
-
-
Persad, S.1
Attwell, S.2
Gray, V.3
Delcommenne, M.4
Troussard, A.5
Sanghera, J.6
Dedhar, S.7
-
17
-
-
0035920145
-
Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: Critical roles for kinase activity and amino acids arginine 211 and serine 343
-
Persad S., Attwell S., Gray V., Mawji N., Deng J.T., Leung D., Yan J., Sanghera J., Walsh M.P., Dedhar S. Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343. J. Biol. Chem. 276:2001;27462-27469.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27462-27469
-
-
Persad, S.1
Attwell, S.2
Gray, V.3
Mawji, N.4
Deng, J.T.5
Leung, D.6
Yan, J.7
Sanghera, J.8
Walsh, M.P.9
Dedhar, S.10
-
18
-
-
0035844886
-
Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation
-
Persad S., Troussard A.A., McPhee T.R., Mulholland D.J., Dedhar S. Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation. J. Cell Biol. 153:2001;1161-1174.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1161-1174
-
-
Persad, S.1
Troussard, A.A.2
McPhee, T.R.3
Mulholland, D.J.4
Dedhar, S.5
-
19
-
-
0033599029
-
Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism
-
Lynch D.K., Ellis C.A., Edwards P.A., Hiles I.D. Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism. Oncogene. 18:1999;8024-8032.
-
(1999)
Oncogene
, vol.18
, pp. 8024-8032
-
-
Lynch, D.K.1
Ellis, C.A.2
Edwards, P.A.3
Hiles, I.D.4
-
20
-
-
0035809918
-
Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane
-
Zervas C.G., Gregory S.L., Brown N.H. Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane. J. Cell Biol. 152:2001;1007-1018.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 1007-1018
-
-
Zervas, C.G.1
Gregory, S.L.2
Brown, N.H.3
-
21
-
-
0037666792
-
Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation
-
Troussard A.A., Mawji N.M., Ong C., Mui A., St-Arnaud R., Dedhar S. Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation. J. Biol. Chem. 278:2003;22374-22378.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 22374-22378
-
-
Troussard, A.A.1
Mawji, N.M.2
Ong, C.3
Mui, A.4
St-Arnaud, R.5
Dedhar, S.6
-
22
-
-
0035844257
-
Ca2+-independent smooth muscle contraction. a novel function for integrin-linked kinase
-
Deng J.T., Van Lierop J.E., Sutherland C., Walsh M.P. Ca2+-independent smooth muscle contraction. A novel function for integrin-linked kinase. J. Biol. Chem. 276:2001;16365-16373.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16365-16373
-
-
Deng, J.T.1
Van Lierop, J.E.2
Sutherland, C.3
Walsh, M.P.4
-
23
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
Vivanco I., Sawyers C.L. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat. Rev., Cancer. 2:2002;489-501.
-
(2002)
Nat. Rev., Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
24
-
-
0036771764
-
Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway
-
Di-Poi N., Tan N.S., Michalik L., Wahli W., Desvergne B. Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway. Mol. Cell. 10:2002;721-733.
-
(2002)
Mol. Cell
, vol.10
, pp. 721-733
-
-
Di-Poi, N.1
Tan, N.S.2
Michalik, L.3
Wahli, W.4
Desvergne, B.5
-
25
-
-
0026029808
-
Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity
-
Boyle W.J., Smeal T., Defize L.H., Angel P., Woodgett J.R., Karin M., Hunter T. Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity. Cell. 64:1991;573-584.
-
(1991)
Cell
, vol.64
, pp. 573-584
-
-
Boyle, W.J.1
Smeal, T.2
Defize, L.H.3
Angel, P.4
Woodgett, J.R.5
Karin, M.6
Hunter, T.7
-
26
-
-
0026808555
-
Differential regulation of glycogen synthase kinase-3 beta by protein kinase C isotypes
-
Goode N., Hughes K., Woodgett J.R., Parker P.J. Differential regulation of glycogen synthase kinase-3 beta by protein kinase C isotypes. J. Biol. Chem. 267:1992;16878-16882.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 16878-16882
-
-
Goode, N.1
Hughes, K.2
Woodgett, J.R.3
Parker, P.J.4
-
27
-
-
0027512538
-
Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells
-
Nikolakaki E., Coffer P.J., Hemelsoet R., Woodgett J.R., Defize L.H. Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells. Oncogene. 8:1993;833-840.
-
(1993)
Oncogene
, vol.8
, pp. 833-840
-
-
Nikolakaki, E.1
Coffer, P.J.2
Hemelsoet, R.3
Woodgett, J.R.4
Defize, L.H.5
-
28
-
-
0026475204
-
Phosphorylation state and DNA-binding activity of c-Jun depend on the intracellular concentration of binding sites
-
Papavassiliou A.G., Chavrier C., Bohmann D. Phosphorylation state and DNA-binding activity of c-Jun depend on the intracellular concentration of binding sites. Proc. Natl. Acad. Sci. U. S. A. 89:1992;11562-11565.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 11562-11565
-
-
Papavassiliou, A.G.1
Chavrier, C.2
Bohmann, D.3
-
29
-
-
0034676338
-
The Integrin Linked Kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent upregulation of matrix metalloproteinase 9 (MMP-9)
-
Troussard A.A., Costello P., Yoganathan T.N., Kumagai S., Roskelley C.D., Dedhar S. The Integrin Linked Kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent upregulation of matrix metalloproteinase 9 (MMP-9). Oncogene. 19:2000;5444-5452.
-
(2000)
Oncogene
, vol.19
, pp. 5444-5452
-
-
Troussard, A.A.1
Costello, P.2
Yoganathan, T.N.3
Kumagai, S.4
Roskelley, C.D.5
Dedhar, S.6
-
30
-
-
0032746701
-
Cell-extracellular matrix interactions stimulate the AP-1 transcription factor in an integrin-linked kinase- and glycogen synthase kinase 3-dependent manner
-
Troussard A.A., Tan C., Yoganathan T.N., Dedhar S. Cell-extracellular matrix interactions stimulate the AP-1 transcription factor in an integrin-linked kinase- and glycogen synthase kinase 3-dependent manner. Mol. Cell. Biol. 19:1999;7420-7427.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7420-7427
-
-
Troussard, A.A.1
Tan, C.2
Yoganathan, T.N.3
Dedhar, S.4
-
31
-
-
0032516094
-
Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways
-
Novak A., Hsu S.C., Leung-Hagesteijn C., Radeva G., Papkoff J., Montesano R., Roskelley C., Grosschedl R., Dedhar S. Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways. Proc. Natl. Acad. Sci. U. S. A. 95:1998;4374-4379.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 4374-4379
-
-
Novak, A.1
Hsu, S.C.2
Leung-Hagesteijn, C.3
Radeva, G.4
Papkoff, J.5
Montesano, R.6
Roskelley, C.7
Grosschedl, R.8
Dedhar, S.9
-
32
-
-
0034601436
-
The integrin-linked kinase (ILK) suppresses anoikis
-
Attwell S., Roskelley C., Dedhar S. The integrin-linked kinase (ILK) suppresses anoikis. Oncogene. 19:2000;3811-3815.
-
(2000)
Oncogene
, vol.19
, pp. 3811-3815
-
-
Attwell, S.1
Roskelley, C.2
Dedhar, S.3
-
33
-
-
0030999580
-
Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression
-
Radeva G., Petrocelli T., Behrend E., Leung-Hagesteijn C., Filmus J., Slingerland J., Dedhar S. Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression. J. Biol. Chem. 272:1997;13937-13944.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13937-13944
-
-
Radeva, G.1
Petrocelli, T.2
Behrend, E.3
Leung-Hagesteijn, C.4
Filmus, J.5
Slingerland, J.6
Dedhar, S.7
-
34
-
-
0035804215
-
Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells
-
Tan C., Costello P., Sanghera J., Dominguez D., Baulida J., de Herreros A.G., Dedhar S. Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells. Oncogene. 20:2001;133-140.
-
(2001)
Oncogene
, vol.20
, pp. 133-140
-
-
Tan, C.1
Costello, P.2
Sanghera, J.3
Dominguez, D.4
Baulida, J.5
De Herreros, A.G.6
Dedhar, S.7
-
35
-
-
0034692686
-
The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3 beta and cAMP-responsive element-binding protein-dependent pathways
-
D'Amico M., Hulit J., Amanatullah D.F., Zafonte B.T., Albanese C., Bouzahzah B., Fu M., Augenlicht L.H., Donehower L.A., Takemaru K., Moon R.T., Davis R., Lisanti M.P., Shtutman M., Zhurinsky J., Ben-Ze'ev A., Troussard A.A., Dedhar S., Pestell R.G. The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3 beta and cAMP-responsive element-binding protein-dependent pathways. J. Biol. Chem. 275:2000;32649-32657.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32649-32657
-
-
D'Amico, M.1
Hulit, J.2
Amanatullah, D.F.3
Zafonte, B.T.4
Albanese, C.5
Bouzahzah, B.6
Fu, M.7
Augenlicht, L.H.8
Donehower, L.A.9
Takemaru, K.10
Moon, R.T.11
Davis, R.12
Lisanti, M.P.13
Shtutman, M.14
Zhurinsky, J.15
Ben-Ze'Ev, A.16
Troussard, A.A.17
Dedhar, S.18
Pestell, R.G.19
-
36
-
-
0036479113
-
Integrin-linked kinase regulates inducible nitric oxide synthase and cyclooxygenase-2 expression in an NF-kappa B-dependent manner
-
Tan C., Mui A., Dedhar S. Integrin-linked kinase regulates inducible nitric oxide synthase and cyclooxygenase-2 expression in an NF-kappa B-dependent manner. J. Biol. Chem. 277:2002;3109-3116.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3109-3116
-
-
Tan, C.1
Mui, A.2
Dedhar, S.3
-
37
-
-
0345103747
-
Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation
-
Sakai T., Li S., Docheva D., Grashoff C., Sakai K., Kostka G., Braun A., Pfeifer A., Yurchenco P.D., Fassler R. Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation. Genes Dev. 17:2003;926-940.
-
(2003)
Genes Dev.
, vol.17
, pp. 926-940
-
-
Sakai, T.1
Li, S.2
Docheva, D.3
Grashoff, C.4
Sakai, K.5
Kostka, G.6
Braun, A.7
Pfeifer, A.8
Yurchenco, P.D.9
Fassler, R.10
-
38
-
-
12144286718
-
Regulation of Tumor Angiogenesis by Integrin-Linked Kinase (ILK)
-
(in press).
-
C. Tan, S. Cruet-Hennequart, A. Troussard, L. Fazili, P. Costello, K. Sutton, J. Wheeler, M. Gleave, J. Sanghera, S. Dedhar, Regulation of Tumor Angiogenesis by Integrin-Linked Kinase (ILK), Cancer Cell (in press).
-
Cancer Cell
-
-
Tan, C.1
Cruet-Hennequart, S.2
Troussard, A.3
Fazili, L.4
Costello, P.5
Sutton, K.6
Wheeler, J.7
Gleave, M.8
Sanghera, J.9
Dedhar, S.10
-
39
-
-
0038323946
-
Integrin-linked kinase regulates chondrocyte shape and proliferation
-
Grashoff C., Aszodi A., Sakai T., Hunziker E.B., Fassler R. Integrin-linked kinase regulates chondrocyte shape and proliferation. EMBO Rep. 4:2003;432-438.
-
(2003)
EMBO Rep.
, vol.4
, pp. 432-438
-
-
Grashoff, C.1
Aszodi, A.2
Sakai, T.3
Hunziker, E.B.4
Fassler, R.5
-
40
-
-
0038148536
-
Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes
-
Terpstra L., Prud'homme J., Arabian A., Takeda S., Karsenty G., Dedhar S., St-Arnaud R. Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes. J. Cell Biol. 162:2003;139-148.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 139-148
-
-
Terpstra, L.1
Prud'Homme, J.2
Arabian, A.3
Takeda, S.4
Karsenty, G.5
Dedhar, S.6
St-Arnaud, R.7
-
41
-
-
0035067120
-
Overexpression of the integrin-linked kinase mesenchymally transforms mammary epithelial cells
-
Somasiri A., Howarth A., Goswami D., Dedhar S., Roskelley C.D. Overexpression of the integrin-linked kinase mesenchymally transforms mammary epithelial cells. J. Cell. Sci. 114:2001;1125-1136.
-
(2001)
J. Cell. Sci.
, vol.114
, pp. 1125-1136
-
-
Somasiri, A.1
Howarth, A.2
Goswami, D.3
Dedhar, S.4
Roskelley, C.D.5
-
42
-
-
0035950544
-
Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice
-
White D.E., Cardiff R.D., Dedhar S., Muller W.J. Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice. Oncogene. 20:2001;7064-7072.
-
(2001)
Oncogene
, vol.20
, pp. 7064-7072
-
-
White, D.E.1
Cardiff, R.D.2
Dedhar, S.3
Muller, W.J.4
-
43
-
-
0141891463
-
Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival
-
Dai D.L., Makretsov N., Campos E.I., Huang C., Zhou Y., Huntsman D., Martinka M., Li G. Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival. Clin. Cancer Res. 9:2003;4409-4414.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 4409-4414
-
-
Dai, D.L.1
Makretsov, N.2
Campos, E.I.3
Huang, C.4
Zhou, Y.5
Huntsman, D.6
Martinka, M.7
Li, G.8
-
44
-
-
0141995796
-
Integrin-linked kinase expression increases with ovarian tumour grade and is sustained by peritoneal tumour fluid
-
Ahmed N., Riley C., Oliva K., Stutt E., Rice E.G., Quinn A.M. Integrin-linked kinase expression increases with ovarian tumour grade and is sustained by peritoneal tumour fluid. J. Pathol. 201:2003;229-237.
-
(2003)
J. Pathol.
, vol.201
, pp. 229-237
-
-
Ahmed, N.1
Riley, C.2
Oliva, K.3
Stutt, E.4
Rice, E.G.5
Quinn, A.M.6
-
45
-
-
0037295608
-
Expression of integrin-linked kinase is closely correlated with invasion and metastasis of gastric carcinoma
-
Ito R., Oue N., Zhu X., Yoshida K., Nakayama H., Yokozaki H., Yasui W. Expression of integrin-linked kinase is closely correlated with invasion and metastasis of gastric carcinoma. Virchows Arch. 442:2003;118-123.
-
(2003)
Virchows Arch.
, vol.442
, pp. 118-123
-
-
Ito, R.1
Oue, N.2
Zhu, X.3
Yoshida, K.4
Nakayama, H.5
Yokozaki, H.6
Yasui, W.7
-
46
-
-
0038751716
-
Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3beta (GSK-3beta) in vitro
-
Cordes N., van Beuningen D. Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3beta (GSK-3beta) in vitro. Br. J. Cancer. 88:2003;1470-1479.
-
(2003)
Br. J. Cancer
, vol.88
, pp. 1470-1479
-
-
Cordes, N.1
Van Beuningen, D.2
-
47
-
-
0038604840
-
Characterisation of integrin-linked kinase signalling in sporadic human colon cancer
-
Marotta A., Parhar K., Owen D., Dedhar S., Salh B. Characterisation of integrin-linked kinase signalling in sporadic human colon cancer. Br. J. Cancer. 88:2003;1755-1762.
-
(2003)
Br. J. Cancer
, vol.88
, pp. 1755-1762
-
-
Marotta, A.1
Parhar, K.2
Owen, D.3
Dedhar, S.4
Salh, B.5
-
48
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
Thiery J.P. Epithelial-mesenchymal transitions in tumour progression. Nat. Rev., Cancer. 2:2002;442-454.
-
(2002)
Nat. Rev., Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
49
-
-
0029900187
-
Cadherin/catenin complex: A target for antiinvasive therapy?
-
Mareel M., Berx G., Van Roy F., Bracke M. Cadherin/catenin complex: a target for antiinvasive therapy? J. Cell. Biochem. 61:1996;524-530.
-
(1996)
J. Cell. Biochem.
, vol.61
, pp. 524-530
-
-
Mareel, M.1
Berx, G.2
Van Roy, F.3
Bracke, M.4
-
50
-
-
0031686745
-
Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression
-
Llorens A., Rodrigo I., Lopez-Barcons L., Gonzalez-Garrigues M., Lozano E., Vinyals A., Quintanilla M., Cano A., Fabra A. Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression. Lab. Invest. 78:1998;1131-1142.
-
(1998)
Lab. Invest.
, vol.78
, pp. 1131-1142
-
-
Llorens, A.1
Rodrigo, I.2
Lopez-Barcons, L.3
Gonzalez-Garrigues, M.4
Lozano, E.5
Vinyals, A.6
Quintanilla, M.7
Cano, A.8
Fabra, A.9
-
51
-
-
0028205806
-
Enlarged cell-associated proteoglycans abolish E-cadherin functionality in invasive tumor cells
-
Vleminckx K.L., Deman J.J., Bruyneel E.A., Vandenbossche G.M., Keirsebilck A.A., Mareel M.M., van Roy F.M. Enlarged cell-associated proteoglycans abolish E-cadherin functionality in invasive tumor cells. Cancer Res. 54:1994;873-877.
-
(1994)
Cancer Res.
, vol.54
, pp. 873-877
-
-
Vleminckx, K.L.1
Deman, J.J.2
Bruyneel, E.A.3
Vandenbossche, G.M.4
Keirsebilck, A.A.5
Mareel, M.M.6
Van Roy, F.M.7
-
52
-
-
0032510494
-
A causal role for E-cadherin in the transition from adenoma to carcinoma
-
Perl A.K., Wilgenbus P., Dahl U., Semb H., Christofori G. A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature. 392:1998;190-193.
-
(1998)
Nature
, vol.392
, pp. 190-193
-
-
Perl, A.K.1
Wilgenbus, P.2
Dahl, U.3
Semb, H.4
Christofori, G.5
-
53
-
-
0029939992
-
E-cadherin mediated adhesion system in cancer cells
-
Shiozaki H., Oka H., Inoue M., Tamura S., Monden M. E-cadherin mediated adhesion system in cancer cells. Cancer. 77:1996;1605-1613.
-
(1996)
Cancer
, vol.77
, pp. 1605-1613
-
-
Shiozaki, H.1
Oka, H.2
Inoue, M.3
Tamura, S.4
Monden, M.5
-
54
-
-
0027282962
-
The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak
-
Burdsal C.A., Damsky C.H., Pedersen R.A. The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak. Development. 118:1993;829-844.
-
(1993)
Development
, vol.118
, pp. 829-844
-
-
Burdsal, C.A.1
Damsky, C.H.2
Pedersen, R.A.3
-
55
-
-
0028293208
-
Selective disruption of E-cadherin function in early Xenopus embryos by a dominant negative mutant
-
Levine E., Lee C.H., Kintner C., Gumbiner B.M. Selective disruption of E-cadherin function in early Xenopus embryos by a dominant negative mutant. Development. 120:1994;901-909.
-
(1994)
Development
, vol.120
, pp. 901-909
-
-
Levine, E.1
Lee, C.H.2
Kintner, C.3
Gumbiner, B.M.4
-
57
-
-
0028821380
-
A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development
-
Riethmacher D., Brinkmann V., Birchmeier C. A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development. Proc. Natl. Acad. Sci. U. S. A. 92:1995;855-859.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 855-859
-
-
Riethmacher, D.1
Brinkmann, V.2
Birchmeier, C.3
-
58
-
-
0030056968
-
Cell adhesion: The molecular basis of tissue architecture and morphogenesis
-
Gumbiner B.M. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell. 84:1996;345-357.
-
(1996)
Cell
, vol.84
, pp. 345-357
-
-
Gumbiner, B.M.1
-
59
-
-
0026534152
-
Regulation of keratinocyte intercellular junction organization and epidermal morphogenesis by E-cadherin
-
Wheelock M.J., Jensen P.J. Regulation of keratinocyte intercellular junction organization and epidermal morphogenesis by E-cadherin. J. Cell Biol. 117:1992;415-425.
-
(1992)
J. Cell Biol.
, vol.117
, pp. 415-425
-
-
Wheelock, M.J.1
Jensen, P.J.2
-
60
-
-
0029160437
-
Morphogenetic roles of classic cadherins
-
Takeichi M. Morphogenetic roles of classic cadherins. Curr. Opin. Cell Biol. 7:1995;619-627.
-
(1995)
Curr. Opin. Cell Biol.
, vol.7
, pp. 619-627
-
-
Takeichi, M.1
-
61
-
-
0032563564
-
Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein
-
Adams C.L., Chen Y.T., Smith S.J., Nelson W.J. Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein. J. Cell Biol. 142:1998;1105-1119.
-
(1998)
J. Cell Biol.
, vol.142
, pp. 1105-1119
-
-
Adams, C.L.1
Chen, Y.T.2
Smith, S.J.3
Nelson, W.J.4
-
62
-
-
0027185632
-
From cadherins to catenins: Cytoplasmic protein interactions and regulation of cell adhesion
-
Kemler R. From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 9:1993;317-321.
-
(1993)
Trends Genet.
, vol.9
, pp. 317-321
-
-
Kemler, R.1
-
63
-
-
0034331032
-
Cadherins in embryonic and neural morphogenesis
-
Tepass U., Truong K., Godt D., Ikura M., Peifer M. Cadherins in embryonic and neural morphogenesis. Nat. Rev., Mol. Cell Biol. 1:2000;91-100.
-
(2000)
Nat. Rev., Mol. Cell Biol.
, vol.1
, pp. 91-100
-
-
Tepass, U.1
Truong, K.2
Godt, D.3
Ikura, M.4
Peifer, M.5
-
64
-
-
0037131409
-
Snail induction of epithelial-to-mesenchymal transition in tumor cells is accompanied by MUC-1 repression and ZEB1 expression
-
Guaita S., Puig I., Franci C., Garrido M., Dominguez D., Batlle E., Sancho E., Dedhar S., Garcia De Herreros A., Baulida J. Snail induction of epithelial-to-mesenchymal transition in tumor cells is accompanied by MUC-1 repression and ZEB1 expression. J. Biol. Chem. 277:2002;39209-39216.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39209-39216
-
-
Guaita, S.1
Puig, I.2
Franci, C.3
Garrido, M.4
Dominguez, D.5
Batlle, E.6
Sancho, E.7
Dedhar, S.8
Garcia De Herreros, A.9
Baulida, J.10
-
65
-
-
0141720342
-
Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis
-
Li Y., Yang J., Dai C., Wu C., Liu Y. Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis. J. Clin. Invest. 112:2003;503-516.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 503-516
-
-
Li, Y.1
Yang, J.2
Dai, C.3
Wu, C.4
Liu, Y.5
-
66
-
-
0033784843
-
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
-
Cano A., Perez-Moreno M.A., Rodrigo I., Locascio A., Blanco M.J., del Barrio M.G., Portillo F., Nieto M.A. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2:2000;76-83.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 76-83
-
-
Cano, A.1
Perez-Moreno, M.A.2
Rodrigo, I.3
Locascio, A.4
Blanco, M.J.5
Del Barrio, M.G.6
Portillo, F.7
Nieto, M.A.8
-
67
-
-
0026328043
-
The E-cadherin promoter: Functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element
-
Behrens J., Lowrick O., Klein-Hitpass L., Birchmeier W. The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element. Proc. Natl. Acad. Sci. U. S. A. 88:1991;11495-11499.
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 11495-11499
-
-
Behrens, J.1
Lowrick, O.2
Klein-Hitpass, L.3
Birchmeier, W.4
-
68
-
-
0026410424
-
The structure of the gene coding for the mouse cell adhesion molecule uvomorulin
-
Ringwald M., Baribault H., Schmidt C., Kemler R. The structure of the gene coding for the mouse cell adhesion molecule uvomorulin. Nucleic Acids Res. 19:1991;6533-6539.
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 6533-6539
-
-
Ringwald, M.1
Baribault, H.2
Schmidt, C.3
Kemler, R.4
-
69
-
-
0031577787
-
Role of e boxes in the repression of E-cadherin expression
-
Giroldi L.A., Bringuier P.P., de Weijert M., Jansen C., van Bokhoven A., Schalken J.A. Role of E boxes in the repression of E-cadherin expression. Biochem. Biophys. Res. Commun. 241:1997;453-458.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.241
, pp. 453-458
-
-
Giroldi, L.A.1
Bringuier, P.P.2
De Weijert, M.3
Jansen, C.4
Van Bokhoven, A.5
Schalken, J.A.6
-
70
-
-
0033789680
-
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
-
Batlle E., Sancho E., Franci C., Dominguez D., Monfar M., Baulida J., Garcia De Herreros A. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat. Cell Biol. 2:2000;84-89.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 84-89
-
-
Batlle, E.1
Sancho, E.2
Franci, C.3
Dominguez, D.4
Monfar, M.5
Baulida, J.6
Garcia De Herreros, A.7
-
71
-
-
0037086277
-
The SLUG zinc-finger protein represses E-cadherin in breast cancer
-
Hajra K.M., Chen D.Y., Fearon E.R. The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res. 62:2002;1613-1618.
-
(2002)
Cancer Res.
, vol.62
, pp. 1613-1618
-
-
Hajra, K.M.1
Chen, D.Y.2
Fearon, E.R.3
-
72
-
-
0035920152
-
A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions
-
Perez-Moreno M.A., Locascio A., Rodrigo I., Dhondt G., Portillo F., Nieto M.A., Cano A. A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions. J. Biol. Chem. 276:2001;27424-27431.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27424-27431
-
-
Perez-Moreno, M.A.1
Locascio, A.2
Rodrigo, I.3
Dhondt, G.4
Portillo, F.5
Nieto, M.A.6
Cano, A.7
-
73
-
-
0035167812
-
The mouse snail gene encodes a key regulator of the epithelial- mesenchymal transition
-
Carver E.A., Jiang R., Lan Y., Oram K.F., Gridley T. The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol. Cell. Biol. 21:2001;8184-8188.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 8184-8188
-
-
Carver, E.A.1
Jiang, R.2
Lan, Y.3
Oram, K.F.4
Gridley, T.5
-
74
-
-
0035816677
-
Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail
-
Poser I., Dominguez D., de Herreros A.G., Varnai A., Buettner R., Bosserhoff A.K. Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail. J. Biol. Chem. 276:2001;24661-24666.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24661-24666
-
-
Poser, I.1
Dominguez, D.2
De Herreros, A.G.3
Varnai, A.4
Buettner, R.5
Bosserhoff, A.K.6
-
75
-
-
0034964418
-
The two-handed e box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
-
Comijn J., Berx G., Vermassen P., Verschueren K., van Grunsven L., Bruyneel E., Mareel M., Huylebroeck D., van Roy F. The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol. Cell. 7:2001;1267-1278.
-
(2001)
Mol. Cell
, vol.7
, pp. 1267-1278
-
-
Comijn, J.1
Berx, G.2
Vermassen, P.3
Verschueren, K.4
Van Grunsven, L.5
Bruyneel, E.6
Mareel, M.7
Huylebroeck, D.8
Van Roy, F.9
-
76
-
-
0037326569
-
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors
-
Bolos V., Peinado H., Perez-Moreno M.A., Fraga M.F., Esteller M., Cano A. The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J. Cell. Sci. 116:2003;499-511.
-
(2003)
J. Cell. Sci.
, vol.116
, pp. 499-511
-
-
Bolos, V.1
Peinado, H.2
Perez-Moreno, M.A.3
Fraga, M.F.4
Esteller, M.5
Cano, A.6
-
77
-
-
0030066481
-
Mechanisms identified in the transcriptional control of epithelial gene expression
-
Hennig G., Lowrick O., Birchmeier W., Behrens J. Mechanisms identified in the transcriptional control of epithelial gene expression. J. Biol. Chem. 271:1996;595-602.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 595-602
-
-
Hennig, G.1
Lowrick, O.2
Birchmeier, W.3
Behrens, J.4
-
78
-
-
0030752437
-
Transcriptional defects underlie loss of E-cadherin expression in breast cancer
-
Ji X., Woodard A.S., Rimm D.L., Fearon E.R. Transcriptional defects underlie loss of E-cadherin expression in breast cancer. Cell Growth Differ. 8:1997;773-778.
-
(1997)
Cell Growth Differ.
, vol.8
, pp. 773-778
-
-
Ji, X.1
Woodard, A.S.2
Rimm, D.L.3
Fearon, E.R.4
-
79
-
-
0035963314
-
Mechanisms of inactivation of E-cadherin in breast carcinoma: Modification of the two-hit hypothesis of tumor suppressor gene
-
Cheng C.W., Wu P.E., Yu J.C., Huang C.S., Yue C.T., Wu C.W., Shen C.Y. Mechanisms of inactivation of E-cadherin in breast carcinoma: modification of the two-hit hypothesis of tumor suppressor gene. Oncogene. 20:2001;3814-3823.
-
(2001)
Oncogene
, vol.20
, pp. 3814-3823
-
-
Cheng, C.W.1
Wu, P.E.2
Yu, J.C.3
Huang, C.S.4
Yue, C.T.5
Wu, C.W.6
Shen, C.Y.7
-
80
-
-
0031835432
-
RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2
-
Batsche E., Muchardt C., Behrens J., Hurst H.C., Cremisi C. RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2. Mol. Cell. Biol. 18:1998;3647-3658.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3647-3658
-
-
Batsche, E.1
Muchardt, C.2
Behrens, J.3
Hurst, H.C.4
Cremisi, C.5
-
81
-
-
0033518130
-
Extinction of E-cadherin expression in breast cancer via a dominant repression pathway acting on proximal promoter elements
-
Hajra K.M., Ji X., Fearon E.R. Extinction of E-cadherin expression in breast cancer via a dominant repression pathway acting on proximal promoter elements. Oncogene. 18:1999;7274-7279.
-
(1999)
Oncogene
, vol.18
, pp. 7274-7279
-
-
Hajra, K.M.1
Ji, X.2
Fearon, E.R.3
-
82
-
-
0036513626
-
The snail superfamily of zinc-finger transcription factors
-
Nieto M.A. The snail superfamily of zinc-finger transcription factors. Nat. Rev., Mol. Cell Biol. 3:2002;155-166.
-
(2002)
Nat. Rev., Mol. Cell Biol.
, vol.3
, pp. 155-166
-
-
Nieto, M.A.1
-
83
-
-
0027184973
-
Definition of the DNA-binding site repertoire for the Drosophila transcription factor SNAIL
-
Mauhin V., Lutz Y., Dennefeld C., Alberga A. Definition of the DNA-binding site repertoire for the Drosophila transcription factor SNAIL. Nucleic Acids Res. 21:1993;3951-3957.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 3951-3957
-
-
Mauhin, V.1
Lutz, Y.2
Dennefeld, C.3
Alberga, A.4
-
84
-
-
0032126746
-
The transition to endoreduplication in trophoblast giant cells is regulated by the mSNA zinc finger transcription factor
-
Nakayama H., Scott I.C., Cross J.C. The transition to endoreduplication in trophoblast giant cells is regulated by the mSNA zinc finger transcription factor. Dev. Biol. 199:1998;150-163.
-
(1998)
Dev. Biol.
, vol.199
, pp. 150-163
-
-
Nakayama, H.1
Scott, I.C.2
Cross, J.C.3
-
85
-
-
0028019579
-
Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot
-
Fuse N., Hirose S., Hayashi S. Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot. Genes Dev. 8:1994;2270-2281.
-
(1994)
Genes Dev.
, vol.8
, pp. 2270-2281
-
-
Fuse, N.1
Hirose, S.2
Hayashi, S.3
-
86
-
-
0033197879
-
SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein
-
Inukai T., Inoue A., Kurosawa H., Goi K., Shinjyo T., Ozawa K., Mao M., Inaba T., Look A.T. SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein. Mol. Cell. 4:1999;343-352.
-
(1999)
Mol. Cell
, vol.4
, pp. 343-352
-
-
Inukai, T.1
Inoue, A.2
Kurosawa, H.3
Goi, K.4
Shinjyo, T.5
Ozawa, K.6
Mao, M.7
Inaba, T.8
Look, A.T.9
-
87
-
-
0031005659
-
The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition
-
Savagner P., Yamada K.M., Thiery J.P. The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition. J. Cell Biol. 137:1997;1403-1419.
-
(1997)
J. Cell Biol.
, vol.137
, pp. 1403-1419
-
-
Savagner, P.1
Yamada, K.M.2
Thiery, J.P.3
-
88
-
-
0034193218
-
Snail-related transcriptional repressors are required in Xenopus for both the induction of the neural crest and its subsequent migration
-
LaBonne C., Bronner-Fraser M. Snail-related transcriptional repressors are required in Xenopus for both the induction of the neural crest and its subsequent migration. Dev. Biol. 221:2000;195-205.
-
(2000)
Dev. Biol.
, vol.221
, pp. 195-205
-
-
Labonne, C.1
Bronner-Fraser, M.2
-
89
-
-
0342409273
-
A novel function for the Xslug gene: Control of dorsal mesendoderm development by repressing BMP-4
-
Mayor R., Guerrero N., Young R.M., Gomez-Skarmeta J.L., Cuellar C. A novel function for the Xslug gene: control of dorsal mesendoderm development by repressing BMP-4. Mech. Dev. 97:2000;47-56.
-
(2000)
Mech. Dev.
, vol.97
, pp. 47-56
-
-
Mayor, R.1
Guerrero, N.2
Young, R.M.3
Gomez-Skarmeta, J.L.4
Cuellar, C.5
-
90
-
-
0034650716
-
A novel snail-related transcription factor Smuc regulates basic helix-loop-helix transcription factor activities via specific E-box motifs
-
Kataoka H., Murayama T., Yokode M., Mori S., Sano H., Ozaki H., Yokota Y., Nishikawa S., Kita T. A novel snail-related transcription factor Smuc regulates basic helix-loop-helix transcription factor activities via specific E-box motifs. Nucleic Acids Res. 28:2000;626-633.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 626-633
-
-
Kataoka, H.1
Murayama, T.2
Yokode, M.3
Mori, S.4
Sano, H.5
Ozaki, H.6
Yokota, Y.7
Nishikawa, S.8
Kita, T.9
-
91
-
-
0031903097
-
The snail repressor establishes a muscle/notochord boundary in the Ciona embryo
-
Fujiwara S., Corbo J.C., Levine M. The snail repressor establishes a muscle/notochord boundary in the Ciona embryo. Development. 125:1998;2511-2520.
-
(1998)
Development
, vol.125
, pp. 2511-2520
-
-
Fujiwara, S.1
Corbo, J.C.2
Levine, M.3
-
92
-
-
0033916759
-
Human Slug is a repressor that localizes to sites of active transcription
-
Hemavathy K., Guru S.C., Harris J., Chen J.D., Ip Y.T. Human Slug is a repressor that localizes to sites of active transcription. Mol. Cell. Biol. 20:2000;5087-5095.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5087-5095
-
-
Hemavathy, K.1
Guru, S.C.2
Harris, J.3
Chen, J.D.4
Ip, Y.T.5
-
93
-
-
0037033693
-
Inverse correlation between E-cadherin and Snail expression in hepatocellular carcinoma cell lines in vitro and in vivo
-
Jiao W., Miyazaki K., Kitajima Y. Inverse correlation between E-cadherin and Snail expression in hepatocellular carcinoma cell lines in vitro and in vivo. Br. J. Cancer. 86:2002;98-101.
-
(2002)
Br. J. Cancer
, vol.86
, pp. 98-101
-
-
Jiao, W.1
Miyazaki, K.2
Kitajima, Y.3
-
94
-
-
0034612270
-
Differential expression and function of members of the zfh-1 family of zinc finger/homeodomain repressors
-
Postigo A.A., Dean D.C. Differential expression and function of members of the zfh-1 family of zinc finger/homeodomain repressors. Proc. Natl. Acad. Sci. U. S. A. 97:2000;6391-6396.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 6391-6396
-
-
Postigo, A.A.1
Dean, D.C.2
-
95
-
-
0033513540
-
Independent repressor domains in ZEB regulate muscle and T-cell differentiation
-
Postigo A.A., Dean D.C. Independent repressor domains in ZEB regulate muscle and T-cell differentiation. Mol. Cell. Biol. 19:1999;7961-7971.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7961-7971
-
-
Postigo, A.A.1
Dean, D.C.2
-
96
-
-
0028318730
-
Control of cell behavior during vertebrate development by Slug, a zinc finger gene
-
Nieto M.A., Sargent M.G., Wilkinson D.G., Cooke J. Control of cell behavior during vertebrate development by Slug, a zinc finger gene. Science. 264:1994;835-839.
-
(1994)
Science
, vol.264
, pp. 835-839
-
-
Nieto, M.A.1
Sargent, M.G.2
Wilkinson, D.G.3
Cooke, J.4
-
97
-
-
0032525997
-
The Slug gene is not essential for mesoderm or neural crest development in mice
-
Jiang R., Lan Y., Norton C.R., Sundberg J.P., Gridley T. The Slug gene is not essential for mesoderm or neural crest development in mice. Dev. Biol. 198:1998;277-285.
-
(1998)
Dev. Biol.
, vol.198
, pp. 277-285
-
-
Jiang, R.1
Lan, Y.2
Norton, C.R.3
Sundberg, J.P.4
Gridley, T.5
-
98
-
-
0035872426
-
Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation
-
Ellenrieder V., Hendler S.F., Boeck W., Seufferlein T., Menke A., Ruhland C., Adler G., Gress T.M. Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation. Cancer Res. 61:2001;4222-4228.
-
(2001)
Cancer Res.
, vol.61
, pp. 4222-4228
-
-
Ellenrieder, V.1
Hendler, S.F.2
Boeck, W.3
Seufferlein, T.4
Menke, A.5
Ruhland, C.6
Adler, G.7
Gress, T.M.8
-
99
-
-
11944255353
-
Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential
-
Welch D.R., Fabra A., Nakajima M. Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential. Proc. Natl. Acad. Sci. U. S. A. 87:1990;7678-7682.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 7678-7682
-
-
Welch, D.R.1
Fabra, A.2
Nakajima, M.3
-
100
-
-
0031928528
-
Transforming growth factor beta1 is associated with angiogenesis, metastasis, and poor clinical outcome in prostate cancer
-
Wikstrom P., Stattin P., Franck-Lissbrant I., Damber J.E., Bergh A. Transforming growth factor beta1 is associated with angiogenesis, metastasis, and poor clinical outcome in prostate cancer. Prostate. 37:1998;19-29.
-
(1998)
Prostate
, vol.37
, pp. 19-29
-
-
Wikstrom, P.1
Stattin, P.2
Franck-Lissbrant, I.3
Damber, J.E.4
Bergh, A.5
-
101
-
-
0030598681
-
TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
-
Cui W., Fowlis D.J., Bryson S., Duffie E., Ireland H., Balmain A., Akhurst R.J. TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cell. 86:1996;531-542.
-
(1996)
Cell
, vol.86
, pp. 531-542
-
-
Cui, W.1
Fowlis, D.J.2
Bryson, S.3
Duffie, E.4
Ireland, H.5
Balmain, A.6
Akhurst, R.J.7
-
102
-
-
0029662049
-
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
-
Oft M., Peli J., Rudaz C., Schwarz H., Beug H., Reichmann E. TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev. 10:1996;2462-2477.
-
(1996)
Genes Dev.
, vol.10
, pp. 2462-2477
-
-
Oft, M.1
Peli, J.2
Rudaz, C.3
Schwarz, H.4
Beug, H.5
Reichmann, E.6
-
103
-
-
0038756636
-
Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: Mechanisms for epithelial mesenchymal transitions
-
Peinado H., Quintanilla M., Cano A. Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J. Biol. Chem. 278:2003;21113-21123.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21113-21123
-
-
Peinado, H.1
Quintanilla, M.2
Cano, A.3
-
104
-
-
0037148532
-
Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: Dissection of Ras signaling pathways
-
Janda E., Lehmann K., Killisch I., Jechlinger M., Herzig M., Downward J., Beug H., Grunert S. Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. J. Cell Biol. 156:2002;299-313.
-
(2002)
J. Cell Biol.
, vol.156
, pp. 299-313
-
-
Janda, E.1
Lehmann, K.2
Killisch, I.3
Jechlinger, M.4
Herzig, M.5
Downward, J.6
Beug, H.7
Grunert, S.8
-
105
-
-
0034666839
-
Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: A mechanism leading to increased malignancy in epithelial cells
-
Lehmann K., Janda E., Pierreux C.E., Rytomaa M., Schulze A., McMahon M., Hill C.S., Beug H., Downward J. Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells. Genes Dev. 14:2000;2610-2622.
-
(2000)
Genes Dev.
, vol.14
, pp. 2610-2622
-
-
Lehmann, K.1
Janda, E.2
Pierreux, C.E.3
Rytomaa, M.4
Schulze, A.5
McMahon, M.6
Hill, C.S.7
Beug, H.8
Downward, J.9
-
106
-
-
0042704731
-
Arg-Gly-Asp-Ser (RGDS) peptide stimulates transforming growth factor beta1 transcription and secretion through integrin activation
-
Ortega-Velazquez R., Diez-Marques M.L., Ruiz-Torres M.P., Gonzalez-Rubio M., Rodriguez-Puyol M., Rodriguez-Puyol D. Arg-Gly-Asp-Ser (RGDS) peptide stimulates transforming growth factor beta1 transcription and secretion through integrin activation. FASEB J. 17:2003;1529-1531.
-
(2003)
FASEB J.
, vol.17
, pp. 1529-1531
-
-
Ortega-Velazquez, R.1
Diez-Marques, M.L.2
Ruiz-Torres, M.P.3
Gonzalez-Rubio, M.4
Rodriguez-Puyol, M.5
Rodriguez-Puyol, D.6
-
107
-
-
0035991607
-
Direct evidence for a role of beta-catenin/LEF-1 signaling pathway in induction of EMT
-
Kim K., Lu Z., Hay E.D. Direct evidence for a role of beta-catenin/LEF-1 signaling pathway in induction of EMT. Cell Biol. Int. 26:2002;463-476.
-
(2002)
Cell Biol. Int.
, vol.26
, pp. 463-476
-
-
Kim, K.1
Lu, Z.2
Hay, E.D.3
-
108
-
-
0025933683
-
Biosynthesis of the cell adhesion molecule uvomorulin (E-cadherin) in Madin-Darby canine kidney epithelial cells
-
Shore E.M., Nelson W.J. Biosynthesis of the cell adhesion molecule uvomorulin (E-cadherin) in Madin-Darby canine kidney epithelial cells. J. Biol. Chem. 266:1991;19672-19680.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 19672-19680
-
-
Shore, E.M.1
Nelson, W.J.2
-
109
-
-
0034617148
-
Differential regulation of endogenous cadherin expression in Madin-Darby canine kidney cells by cell-cell adhesion and activation of beta-catenin signaling
-
Stewart D.B., Barth A.I., Nelson W.J. Differential regulation of endogenous cadherin expression in Madin-Darby canine kidney cells by cell-cell adhesion and activation of beta-catenin signaling. J. Biol. Chem. 275:2000;20707-20716.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20707-20716
-
-
Stewart, D.B.1
Barth, A.I.2
Nelson, W.J.3
-
110
-
-
0034798707
-
Leaving the neighborhood: Molecular mechanisms involved during epithelial-mesenchymal transition
-
Savagner P. Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition. BioEssays. 23:2001;912-923.
-
(2001)
BioEssays
, vol.23
, pp. 912-923
-
-
Savagner, P.1
-
111
-
-
0029553183
-
An overview of epithelio-mesenchymal transformation
-
Hay E.D. An overview of epithelio-mesenchymal transformation. Acta Anat. (Basel). 154:1995;8-20.
-
(1995)
Acta Anat. (Basel)
, vol.154
, pp. 8-20
-
-
Hay, E.D.1
-
112
-
-
0036617188
-
TGFbeta3-induced activation of RhoA/Rho-kinase pathway is necessary but not sufficient for epithelio-mesenchymal transdifferentiation: Implications for palatogenesis
-
Kaartinen V., Haataja L., Nagy A., Heisterkamp N., Groffen J. TGFbeta3-induced activation of RhoA/Rho-kinase pathway is necessary but not sufficient for epithelio-mesenchymal transdifferentiation: implications for palatogenesis. Int. J. Mol. Med. 9:2002;563-570.
-
(2002)
Int. J. Mol. Med.
, vol.9
, pp. 563-570
-
-
Kaartinen, V.1
Haataja, L.2
Nagy, A.3
Heisterkamp, N.4
Groffen, J.5
-
113
-
-
0028234672
-
A scatter factor-like factor is produced by a metastatic variant of a rat bladder carcinoma cell line
-
Bellusci S., Moens G., Thiery J.P., Jouanneau J. A scatter factor-like factor is produced by a metastatic variant of a rat bladder carcinoma cell line. J. Cell. Sci. 107(Pt 5):1994;1277-1287.
-
(1994)
J. Cell. Sci.
, vol.107
, Issue.PT 5
, pp. 1277-1287
-
-
Bellusci, S.1
Moens, G.2
Thiery, J.P.3
Jouanneau, J.4
-
114
-
-
0035011168
-
Genes and proteins involved in mesenchymal to epithelial transition
-
Barasch J. Genes and proteins involved in mesenchymal to epithelial transition. Curr. Opin. Nephrol. Hypertens. 10:2001;429-436.
-
(2001)
Curr. Opin. Nephrol. Hypertens.
, vol.10
, pp. 429-436
-
-
Barasch, J.1
-
115
-
-
0033995537
-
Kidney morphogenesis: Cellular and molecular regulation
-
Kuure S., Vuolteenaho R., Vainio S. Kidney morphogenesis: cellular and molecular regulation. Mech. Dev. 92:2000;31-45.
-
(2000)
Mech. Dev.
, vol.92
, pp. 31-45
-
-
Kuure, S.1
Vuolteenaho, R.2
Vainio, S.3
-
116
-
-
0032729458
-
Signaling through beta-catenin and Lef/Tcf
-
Novak A., Dedhar S. Signaling through beta-catenin and Lef/Tcf. Cell. Mol. Life Sci. 56:1999;523-537.
-
(1999)
Cell. Mol. Life Sci.
, vol.56
, pp. 523-537
-
-
Novak, A.1
Dedhar, S.2
-
117
-
-
0028035292
-
Unraveling the cytoplasmic interactions of the cadherin superfamily
-
Cowin P. Unraveling the cytoplasmic interactions of the cadherin superfamily. Proc. Natl. Acad. Sci. U. S. A. 91:1994;10759-10761.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 10759-10761
-
-
Cowin, P.1
-
118
-
-
0024451982
-
The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species
-
Ozawa M., Baribault H., Kemler R. The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO J. 8:1989;1711-1717.
-
(1989)
EMBO J.
, vol.8
, pp. 1711-1717
-
-
Ozawa, M.1
Baribault, H.2
Kemler, R.3
-
119
-
-
0024755646
-
Transmembrane control of cadherin-mediated cell adhesion: A 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin
-
Nagafuchi A., Takeichi M. Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin. Cell Regul. 1:1989;37-44.
-
(1989)
Cell Regul.
, vol.1
, pp. 37-44
-
-
Nagafuchi, A.1
Takeichi, M.2
-
120
-
-
0025374899
-
Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule
-
Ozawa M., Ringwald M., Kemler R. Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc. Natl. Acad. Sci. U. S. A. 87:1990;4246-4250.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 4246-4250
-
-
Ozawa, M.1
Ringwald, M.2
Kemler, R.3
-
121
-
-
0026316099
-
A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin
-
McCrea P.D., Turck C.W., Gumbiner B. A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. Science. 254:1991;1359-1361.
-
(1991)
Science
, vol.254
, pp. 1359-1361
-
-
McCrea, P.D.1
Turck, C.W.2
Gumbiner, B.3
-
122
-
-
0025729647
-
The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation
-
Peifer M., Rauskolb C., Williams M., Riggleman B., Wieschaus E. The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation. Development. 111:1991;1029-1043.
-
(1991)
Development
, vol.111
, pp. 1029-1043
-
-
Peifer, M.1
Rauskolb, C.2
Williams, M.3
Riggleman, B.4
Wieschaus, E.5
-
123
-
-
0029920839
-
Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes
-
Papkoff J., Rubinfeld B., Schryver B., Polakis P. Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes. Mol. Cell. Biol. 16:1996;2128-2134.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2128-2134
-
-
Papkoff, J.1
Rubinfeld, B.2
Schryver, B.3
Polakis, P.4
-
124
-
-
0030917251
-
A versatile transcriptional effector of Wingless signaling
-
Nusse R. A versatile transcriptional effector of Wingless signaling. Cell. 89:1997;321-323.
-
(1997)
Cell
, vol.89
, pp. 321-323
-
-
Nusse, R.1
-
125
-
-
0029991079
-
Genomic organization of the human beta-catenin gene (CTNNB1)
-
Nollet F., Berx G., Molemans F., van Roy F. Genomic organization of the human beta-catenin gene (CTNNB1). Genomics. 32:1996;413-424.
-
(1996)
Genomics
, vol.32
, pp. 413-424
-
-
Nollet, F.1
Berx, G.2
Molemans, F.3
Van Roy, F.4
-
126
-
-
0029781509
-
Functional interaction of beta-catenin with the transcription factor LEF-1
-
Behrens J., von Kries J.P., Kuhl M., Bruhn L., Wedlich D., Grosschedl R., Birchmeier W. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature. 382:1996;638-642.
-
(1996)
Nature
, vol.382
, pp. 638-642
-
-
Behrens, J.1
Von Kries, J.P.2
Kuhl, M.3
Bruhn, L.4
Wedlich, D.5
Grosschedl, R.6
Birchmeier, W.7
-
127
-
-
0031456158
-
Wnt signaling: A common theme in animal development
-
Cadigan K.M., Nusse R. Wnt signaling: a common theme in animal development. Genes Dev. 11:1997;3286-3305.
-
(1997)
Genes Dev.
, vol.11
, pp. 3286-3305
-
-
Cadigan, K.M.1
Nusse, R.2
-
128
-
-
0031128225
-
WNTs modulate cell fate and behavior during vertebrate development
-
Moon R.T., Brown J.D., Torres M. WNTs modulate cell fate and behavior during vertebrate development. Trends Genet. 13:1997;157-162.
-
(1997)
Trends Genet.
, vol.13
, pp. 157-162
-
-
Moon, R.T.1
Brown, J.D.2
Torres, M.3
-
129
-
-
0021270667
-
Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15
-
Nusse R., van Ooyen A., Cox D., Fung Y.K., Varmus H. Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15. Nature. 307:1984;131-136.
-
(1984)
Nature
, vol.307
, pp. 131-136
-
-
Nusse, R.1
Van Ooyen, A.2
Cox, D.3
Fung, Y.K.4
Varmus, H.5
-
130
-
-
0030900696
-
Stabilization of beta-catenin by genetic defects in melanoma cell lines
-
Rubinfeld B., Robbins P., El-Gamil M., Albert I., Porfiri E., Polakis P. Stabilization of beta-catenin by genetic defects in melanoma cell lines. Science. 275:1997;1790-1792.
-
(1997)
Science
, vol.275
, pp. 1790-1792
-
-
Rubinfeld, B.1
Robbins, P.2
El-Gamil, M.3
Albert, I.4
Porfiri, E.5
Polakis, P.6
-
131
-
-
0030949463
-
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
-
Morin P.J., Sparks A.B., Korinek V., Barker N., Clevers H., Vogelstein B., Kinzler K.W. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science. 275:1997;1787-1790.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogelstein, B.6
Kinzler, K.W.7
-
132
-
-
0022993326
-
A retrovirus vector expressing the putative mammary oncogene int-1 causes partial transformation of a mammary epithelial cell line
-
Brown A.M., Wildin R.S., Prendergast T.J., Varmus H.E. A retrovirus vector expressing the putative mammary oncogene int-1 causes partial transformation of a mammary epithelial cell line. Cell. 46:1986;1001-1009.
-
(1986)
Cell
, vol.46
, pp. 1001-1009
-
-
Brown, A.M.1
Wildin, R.S.2
Prendergast, T.J.3
Varmus, H.E.4
-
133
-
-
0027965236
-
Differential transformation of mammary epithelial cells by Wnt genes
-
Wong G.T., Gavin B.J., McMahon A.P. Differential transformation of mammary epithelial cells by Wnt genes. Mol. Cell. Biol. 14:1994;6278-6286.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6278-6286
-
-
Wong, G.T.1
Gavin, B.J.2
McMahon, A.P.3
-
134
-
-
0033590172
-
Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways
-
Miller J.R., Hocking A.M., Brown J.D., Moon R.T. Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways. Oncogene. 18:1999;7860-7872.
-
(1999)
Oncogene
, vol.18
, pp. 7860-7872
-
-
Miller, J.R.1
Hocking, A.M.2
Brown, J.D.3
Moon, R.T.4
-
135
-
-
0029964851
-
Signal transduction through beta-catenin and specification of cell fate during embryogenesis
-
Miller J.R., Moon R.T. Signal transduction through beta-catenin and specification of cell fate during embryogenesis. Genes Dev. 10:1996;2527-2539.
-
(1996)
Genes Dev.
, vol.10
, pp. 2527-2539
-
-
Miller, J.R.1
Moon, R.T.2
-
136
-
-
0035902040
-
Developmental biology. Making head or tail of Dickkopf
-
Nusse R. Developmental biology. Making head or tail of Dickkopf. Nature. 411:2001;255-256.
-
(2001)
Nature
, vol.411
, pp. 255-256
-
-
Nusse, R.1
-
137
-
-
0037205007
-
The promise and perils of Wnt signaling through beta-catenin
-
Moon R.T., Bowerman B., Boutros M., Perrimon N. The promise and perils of Wnt signaling through beta-catenin. Science. 296:2002;1644-1646.
-
(2002)
Science
, vol.296
, pp. 1644-1646
-
-
Moon, R.T.1
Bowerman, B.2
Boutros, M.3
Perrimon, N.4
-
138
-
-
0035947772
-
E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner
-
Gottardi C.J., Wong E., Gumbiner B.M. E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner. J. Cell Biol. 153:2001;1049-1060.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1049-1060
-
-
Gottardi, C.J.1
Wong, E.2
Gumbiner, B.M.3
-
139
-
-
0032891720
-
E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation
-
Orsulic S., Huber O., Aberle H., Arnold S., Kemler R. E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation. J. Cell. Sci. 112(Pt 8):1999;1237-1245.
-
(1999)
J. Cell. Sci.
, vol.112
, Issue.PT 8
, pp. 1237-1245
-
-
Orsulic, S.1
Huber, O.2
Aberle, H.3
Arnold, S.4
Kemler, R.5
-
140
-
-
0342327346
-
Cadherins, catenins and APC protein: Interplay between cytoskeletal complexes and signaling pathways
-
Barth A.I., Nathke I.S., Nelson W.J. Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways. Curr. Opin. Cell Biol. 9:1997;683-690.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 683-690
-
-
Barth, A.I.1
Nathke, I.S.2
Nelson, W.J.3
-
141
-
-
0033545845
-
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
-
Shtutman M., Zhurinsky J., Simcha I., Albanese C., D'Amico M., Pestell R., Ben-Ze'ev A. The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc. Natl. Acad. Sci. U. S. A. 96:1999;5522-5527.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 5522-5527
-
-
Shtutman, M.1
Zhurinsky, J.2
Simcha, I.3
Albanese, C.4
D'Amico, M.5
Pestell, R.6
Ben-Ze'Ev, A.7
-
142
-
-
0035138178
-
Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling
-
van de Wetering M., Barker N., Harkes I.C., van der Heyden M., Dijk N.J., Hollestelle A., Klijn J.G., Clevers H., Schutte M. Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling. Cancer Res. 61:2001;278-284.
-
(2001)
Cancer Res.
, vol.61
, pp. 278-284
-
-
Van De Wetering, M.1
Barker, N.2
Harkes, I.C.3
Van Der Heyden, M.4
Dijk, N.J.5
Hollestelle, A.6
Klijn, J.G.7
Clevers, H.8
Schutte, M.9
-
143
-
-
0033870244
-
Expression of nuclear beta-catenin and c-myc is correlated with tumor size but not with proliferative activity of colorectal adenomas
-
Brabletz T., Herrmann K., Jung A., Faller G., Kirchner T. Expression of nuclear beta-catenin and c-myc is correlated with tumor size but not with proliferative activity of colorectal adenomas. Am. J. Pathol. 156:2000;865-870.
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 865-870
-
-
Brabletz, T.1
Herrmann, K.2
Jung, A.3
Faller, G.4
Kirchner, T.5
-
144
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He T.C., Sparks A.B., Rago C., Hermeking H., Zawel L., da Costa L.T., Morin P.J., Vogelstein B., Kinzler K.W. Identification of c-MYC as a target of the APC pathway. Science. 281:1998;1509-1512.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
Da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
146
-
-
0030975671
-
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
-
Korinek V., Barker N., Morin P.J., van Wichen D., de Weger R., Kinzler K.W., Vogelstein B., Clevers H. Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science. 275:1997;1784-1787.
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
Van Wichen, D.4
De Weger, R.5
Kinzler, K.W.6
Vogelstein, B.7
Clevers, H.8
-
147
-
-
0032492954
-
Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta
-
Hart M.J., de los Santos R., Albert I.N., Rubinfeld B., Polakis P. Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. Curr. Biol. 8:1998;573-581.
-
(1998)
Curr. Biol.
, vol.8
, pp. 573-581
-
-
Hart, M.J.1
De Los Santos, R.2
Albert, I.N.3
Rubinfeld, B.4
Polakis, P.5
-
148
-
-
0032054828
-
Wnt signaling: Why is everything so negative?
-
Brown J.D., Moon R.T. Wnt signaling: why is everything so negative? Curr. Opin. Cell Biol. 10:1998;182-187.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 182-187
-
-
Brown, J.D.1
Moon, R.T.2
-
149
-
-
0036270763
-
The subcellular destinations of APC proteins
-
Bienz M. The subcellular destinations of APC proteins. Nat. Rev., Mol. Cell Biol. 3:2002;328-338.
-
(2002)
Nat. Rev., Mol. Cell Biol.
, vol.3
, pp. 328-338
-
-
Bienz, M.1
-
150
-
-
0030739838
-
Carcinogenesis: A balance between beta-catenin and APC
-
Gumbiner B.M. Carcinogenesis: a balance between beta-catenin and APC. Curr. Biol. 7:1997;R443-R446.
-
(1997)
Curr. Biol.
, vol.7
, pp. 443-R446
-
-
Gumbiner, B.M.1
-
151
-
-
0031557898
-
The adenomatous polyposis coli (APC) tumor suppressor
-
Polakis P. The adenomatous polyposis coli (APC) tumor suppressor. Biochim. Biophys. Acta. 1332:1997;F127-F147.
-
(1997)
Biochim. Biophys. Acta
, vol.1332
, pp. 127-F147
-
-
Polakis, P.1
-
152
-
-
0033611558
-
Axin prevents Wnt-3a-induced accumulation of beta-catenin
-
Kishida M., Koyama S., Kishida S., Matsubara K., Nakashima S., Higano K., Takada R., Takada S., Kikuchi A. Axin prevents Wnt-3a-induced accumulation of beta-catenin. Oncogene. 18:1999;979-985.
-
(1999)
Oncogene
, vol.18
, pp. 979-985
-
-
Kishida, M.1
Koyama, S.2
Kishida, S.3
Matsubara, K.4
Nakashima, S.5
Higano, K.6
Takada, R.7
Takada, S.8
Kikuchi, A.9
-
153
-
-
0033565533
-
Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex
-
Willert K., Shibamoto S., Nusse R. Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex. Genes Dev. 13:1999;1768-1773.
-
(1999)
Genes Dev.
, vol.13
, pp. 1768-1773
-
-
Willert, K.1
Shibamoto, S.2
Nusse, R.3
-
155
-
-
0038724824
-
The role of integrin-linked kinase (ILK) in cancer progression
-
Persad S., Dedhar S. The role of integrin-linked kinase (ILK) in cancer progression. Cancer Metastasis Rev. 22:2003;375-384.
-
(2003)
Cancer Metastasis Rev.
, vol.22
, pp. 375-384
-
-
Persad, S.1
Dedhar, S.2
-
156
-
-
0035959870
-
Dysregulation of integrin-linked kinase (ILK) signaling in colonic polyposis
-
Marotta A., Tan C., Gray V., Malik S., Gallinger S., Sanghera J., Dupuis B., Owen D., Dedhar S., Salh B. Dysregulation of integrin-linked kinase (ILK) signaling in colonic polyposis. Oncogene. 20:2001;6250-6257.
-
(2001)
Oncogene
, vol.20
, pp. 6250-6257
-
-
Marotta, A.1
Tan, C.2
Gray, V.3
Malik, S.4
Gallinger, S.5
Sanghera, J.6
Dupuis, B.7
Owen, D.8
Dedhar, S.9
Salh, B.10
-
157
-
-
0034717582
-
Colocalization and redistribution of dishevelled and actin during Wnt-induced mesenchymal morphogenesis
-
Torres M.A., Nelson W.J. Colocalization and redistribution of dishevelled and actin during Wnt-induced mesenchymal morphogenesis. J. Cell Biol. 149:2000;1433-1442.
-
(2000)
J. Cell Biol.
, vol.149
, pp. 1433-1442
-
-
Torres, M.A.1
Nelson, W.J.2
-
158
-
-
0033180094
-
Wnt pathway components orient a mitotic spindle in the early Caenorhabditis elegans embryo without requiring gene transcription in the responding cell
-
Schlesinger A., Shelton C.A., Maloof J.N., Meneghini M., Bowerman B. Wnt pathway components orient a mitotic spindle in the early Caenorhabditis elegans embryo without requiring gene transcription in the responding cell. Genes Dev. 13:1999;2028-2038.
-
(1999)
Genes Dev.
, vol.13
, pp. 2028-2038
-
-
Schlesinger, A.1
Shelton, C.A.2
Maloof, J.N.3
Meneghini, M.4
Bowerman, B.5
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