TGF-β type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells

Journal of Cell Science

Volumn 112, Issue 24, 1999, Pages 4557-4568

  Piek, Ester ^a,b   Moustakas, Aristidis ^a   Kurisaki, Akira ^a   Heldin, Carl Henrik ^a   Ten Dijke, Peter ^a,c  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Sweden)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Actin cytoskeleton; Phenotypic transformation; SMAD; TGF receptor; Transdifferentiation

Indexed keywords

ACTIVIN A; ACTIVIN RECEPTOR; OSTEOGENIC PROTEIN 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE C INHIBITOR; SMAD PROTEIN; STAUROSPORINE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; VIRUS VECTOR;

ADENOVIRUS; ANIMAL CELL; ARTICLE; BREAST EPITHELIUM; CELL DIFFERENTIATION; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOSKELETON; EPITHELIUM CELL; GENE ACTIVATION; GENETIC TRANSFECTION; MESENCHYME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING;

ACTIVIN RECEPTORS, TYPE I; ACTIVINS; ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; DOWN-REGULATION; ENZYME INHIBITORS; EPITHELIAL CELLS; INHIBINS; LUCIFERASES; MAMMARY GLANDS, ANIMAL; MESODERM; MICE; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED;

EID: 0033377867     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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