-
1
-
-
0035928391
-
Type 1 diabetes: New perspectives on disease pathogenesis and treatment
-
Atkinson, M. A., & Eisenbarth, G. S. (2001). Type 1 diabetes: New perspectives on disease pathogenesis and treatment. Lancet, 358, 221-229.
-
(2001)
Lancet
, vol.358
, pp. 221-229
-
-
Atkinson, M.A.1
Eisenbarth, G.S.2
-
2
-
-
0035061536
-
Tolerance to islet autoantigens in type 1 diabetes
-
Bach, J. F., & Chatenoud, L. (2001). Tolerance to islet autoantigens in type 1 diabetes. Annual Review of Immunology, 19, 131-161.
-
(2001)
Annual Review of Immunology
, vol.19
, pp. 131-161
-
-
Bach, J.F.1
Chatenoud, L.2
-
3
-
-
0036548159
-
Is type 1 diabetes transmissible by bone marrow allograft?
-
Beard, M. E., Willis, J. A., Scott, R. S., & Nesbit, J. W. (2002). Is type 1 diabetes transmissible by bone marrow allograft? Diabetes Care, 25, 799-800.
-
(2002)
Diabetes Care
, vol.25
, pp. 799-800
-
-
Beard, M.E.1
Willis, J.A.2
Scott, R.S.3
Nesbit, J.W.4
-
6
-
-
3242768392
-
+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes
-
+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes. Diabetes, 53, 1987-1994.
-
(2004)
Diabetes
, vol.53
, pp. 1987-1994
-
-
Reijonen, H.1
Mallone, R.2
Heninger, A.K.3
Laughlin, E.M.4
Kochik, S.A.5
Falk, B.6
Kwok, W.W.7
Greenbaum, C.8
Nepom, G.T.9
-
8
-
-
0033001488
-
The NOD mouse model of type 1 diabetes: As good as it gets?
-
Atkinson, M. A., & Leiter, E. H. (1999). The NOD mouse model of type 1 diabetes: As good as it gets? Nature Medicine, 5, 601-604.
-
(1999)
Nature Medicine
, vol.5
, pp. 601-604
-
-
Atkinson, M.A.1
Leiter, E.H.2
-
9
-
-
0027399707
-
Thymic T cell anergy in autoimmune nonobese diabetic mice is mediated by deficient T cell receptor regulation of the pathway of p21ras activation
-
Rapoport, M. J., Lazarus, A. H., Jaramillo, A., Speck, E., & Delovitch, T. L. (1993). Thymic T cell anergy in autoimmune nonobese diabetic mice is mediated by deficient T cell receptor regulation of the pathway of p21ras activation. Journal of Experimental Medicine, 177, 1221-1226.
-
(1993)
Journal of Experimental Medicine
, vol.177
, pp. 1221-1226
-
-
Rapoport, M.J.1
Lazarus, A.H.2
Jaramillo, A.3
Speck, E.4
Delovitch, T.L.5
-
10
-
-
0029825150
-
+-like thymocytes in the NOD mouse
-
+-like thymocytes in the NOD mouse. European Journal of Immunology, 26, 2989-2998.
-
(1996)
European Journal of Immunology
, vol.26
, pp. 2989-2998
-
-
Gombert, J.M.1
Herbelin, A.2
Tancrede-Bohin, E.3
Dy, M.4
Carnaud, C.5
Bach, J.F.6
-
11
-
-
1942453326
-
Homeostatic expansion of T cells during immune insufficiency generates autoimmunity
-
King, C., Ilic, A., Koelsch, K., & Sarvetnick, N. (2004). Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. Cell, 117, 265-277.
-
(2004)
Cell
, vol.117
, pp. 265-277
-
-
King, C.1
Ilic, A.2
Koelsch, K.3
Sarvetnick, N.4
-
12
-
-
0019448022
-
Defective suppressor cell generation in juvenile onset diabetes
-
Lederman, M. M., Ellner, J. J., & Rodman, H. M. (1981). Defective suppressor cell generation in juvenile onset diabetes. Journal of Immunology, 127, 2051-2055.
-
(1981)
Journal of Immunology
, vol.127
, pp. 2051-2055
-
-
Lederman, M.M.1
Ellner, J.J.2
Rodman, H.M.3
-
13
-
-
0029788211
-
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
-
Asano, M., Toda, M., Sakaguchi, N., & Sakaguchi, S. (1996). Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. Journal of Experimental Medicine, 184, 387-396.
-
(1996)
Journal of Experimental Medicine
, vol.184
, pp. 387-396
-
-
Asano, M.1
Toda, M.2
Sakaguchi, N.3
Sakaguchi, S.4
-
14
-
-
0033682056
-
+ immunoregulatory T cells that control autoimmune diabetes
-
+ immunoregulatory T cells that control autoimmune diabetes. Immunity, 12, 431-440.
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.1
Lenschow, D.J.2
Rhee, L.3
Ashourian, N.4
Singh, B.5
Sharpe, A.6
Bluestone, J.A.7
-
16
-
-
0036644326
-
Aberrant production of IL-12 by macrophages from several autoimmune-prone mouse strains is characterized by intrinsic and unique patterns of NF-kappa B expression and binding to the IL-12 p40 promoter
-
Liu, J., & Beller, D. (2002). Aberrant production of IL-12 by macrophages from several autoimmune-prone mouse strains is characterized by intrinsic and unique patterns of NF-kappa B expression and binding to the IL-12 p40 promoter. Journal of Immunology, 169, 581-586.
-
(2002)
Journal of Immunology
, vol.169
, pp. 581-586
-
-
Liu, J.1
Beller, D.2
-
17
-
-
0027173029
-
Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice
-
Serreze, D. V., Gaskins, H. R., & Leiter, E. H. (1993). Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice. Journal of Immunology, 150, 2534-2543.
-
(1993)
Journal of Immunology
, vol.150
, pp. 2534-2543
-
-
Serreze, D.V.1
Gaskins, H.R.2
Leiter, E.H.3
-
18
-
-
0033939014
-
Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: Elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice
-
Alleva, D. G., Pavlovich, R. P., Grant, C., Kaser, S. B., & Beller, D. I. (2000). Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: Elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice. Diabetes, 49, 1106-1115.
-
(2000)
Diabetes
, vol.49
, pp. 1106-1115
-
-
Alleva, D.G.1
Pavlovich, R.P.2
Grant, C.3
Kaser, S.B.4
Beller, D.I.5
-
19
-
-
0034161702
-
Low CD86 expression in the nonobese diabetic mouse results in the impairment of both T cell activation and CTLA-4 up-regulation
-
Dahlen, E., Hedlund, G., & Dawe, K. (2000). Low CD86 expression in the nonobese diabetic mouse results in the impairment of both T cell activation and CTLA-4 up-regulation. Journal of Immunology, 164, 2444-2456.
-
(2000)
Journal of Immunology
, vol.164
, pp. 2444-2456
-
-
Dahlen, E.1
Hedlund, G.2
Dawe, K.3
-
20
-
-
0036141438
-
Multiple immuno-regulatory defects in type-1 diabetes
-
Kukreja, A., Cost, G., Marker, J., Zhang, C., Sun, Z., Lin-Su, K., Ten, S., Sanz, M., Exley, M., Wilson, B., Porcelli, S., & Maclaren, N. (2002). Multiple immuno-regulatory defects in type-1 diabetes. Journal of Clinical Investigation, 109, 131-140.
-
(2002)
Journal of Clinical Investigation
, vol.109
, pp. 131-140
-
-
Kukreja, A.1
Cost, G.2
Marker, J.3
Zhang, C.4
Sun, Z.5
Lin-Su, K.6
Ten, S.7
Sanz, M.8
Exley, M.9
Wilson, B.10
Porcelli, S.11
Maclaren, N.12
-
21
-
-
0035424898
-
-
Weaver Jr., D. J., Poligone, B., Bui, T., Abdel-Motal, U. M., Baldwin Jr., A. S., & Tisch, R. (2001). Dendritic cells from nonobese diabetic mice exhibit a defect in NF-kappa B regulation due to a hyperactive I kappa B kinase. Journal of Immunology, 167, 1461-1468.
-
Weaver Jr., D. J., Poligone, B., Bui, T., Abdel-Motal, U. M., Baldwin Jr., A. S., & Tisch, R. (2001). Dendritic cells from nonobese diabetic mice exhibit a defect in NF-kappa B regulation due to a hyperactive I kappa B kinase. Journal of Immunology, 167, 1461-1468.
-
-
-
-
22
-
-
0037223260
-
Impaired processing and presentation by MHC class II proteins in human diabetic cells
-
Yan, G., Shi, L., Penfornis, A., & Faustman, D. L. (2003). Impaired processing and presentation by MHC class II proteins in human diabetic cells. Journal of Immunology, 170, 620-627.
-
(2003)
Journal of Immunology
, vol.170
, pp. 620-627
-
-
Yan, G.1
Shi, L.2
Penfornis, A.3
Faustman, D.L.4
-
23
-
-
0026500437
-
Response of peripheral-blood mononuclear cells to glutamate decarboxylase in insulin-dependent diabetes
-
Atkinson, M. A., Kaufman, D. L., Campbell, L., Gibbs, K. A., Shah, S. C., Bu, D. F., Erlander, M. G., Tobin, A. J., & Maclaren, N. K. (1992). Response of peripheral-blood mononuclear cells to glutamate decarboxylase in insulin-dependent diabetes. Lancet, 339, 458-459.
-
(1992)
Lancet
, vol.339
, pp. 458-459
-
-
Atkinson, M.A.1
Kaufman, D.L.2
Campbell, L.3
Gibbs, K.A.4
Shah, S.C.5
Bu, D.F.6
Erlander, M.G.7
Tobin, A.J.8
Maclaren, N.K.9
-
24
-
-
0028987253
-
T-cell reactivity to beta-cell membrane antigens associated with beta-cell destruction in IDDM
-
Roep, B. O., Kallan, A. A., Duinkerken, G., Arden, S. D., Hutton, J. C., Bruining, G. J., & de Vries, R. R. (1995). T-cell reactivity to beta-cell membrane antigens associated with beta-cell destruction in IDDM. Diabetes, 44, 278-283.
-
(1995)
Diabetes
, vol.44
, pp. 278-283
-
-
Roep, B.O.1
Kallan, A.A.2
Duinkerken, G.3
Arden, S.D.4
Hutton, J.C.5
Bruining, G.J.6
de Vries, R.R.7
-
25
-
-
0028007192
-
Cellular immunity to a determinant common to glutamate decarboxylase and cox-sackie virus in insulin-dependent diabetes
-
Atkinson, M. A., Bowman, M. A., Campbell, L., Darrow, B. L., Kaufman, D. L., & Maclaren, N. K. (1994). Cellular immunity to a determinant common to glutamate decarboxylase and cox-sackie virus in insulin-dependent diabetes. Journal of Clinical Investigation, 94, 2125-2129.
-
(1994)
Journal of Clinical Investigation
, vol.94
, pp. 2125-2129
-
-
Atkinson, M.A.1
Bowman, M.A.2
Campbell, L.3
Darrow, B.L.4
Kaufman, D.L.5
Maclaren, N.K.6
-
26
-
-
0030589224
-
Peripheral blood mononuclear cells of insulin-dependent diabetic patients respond to multiple islet cell proteins
-
Brooks-Worrell, B. M., Starkebaum, G. A., Greenbaum, C., & Palmer, J. P. (1996). Peripheral blood mononuclear cells of insulin-dependent diabetic patients respond to multiple islet cell proteins. Journal of Immunology, 157, 5668-5674.
-
(1996)
Journal of Immunology
, vol.157
, pp. 5668-5674
-
-
Brooks-Worrell, B.M.1
Starkebaum, G.A.2
Greenbaum, C.3
Palmer, J.P.4
-
27
-
-
0032701129
-
Naturally processed and presented epitopes of the islet cell autoantigen IA-2 eluted from HLA-DR4
-
Peakman, M., Stevens, E. J., Lohmann, T., Narendran, P., Dromey, J., Alexander, A., Tomlinson, A. J., Trucco, M., Gorga, J. C., & Chicz, R. M. (1999). Naturally processed and presented epitopes of the islet cell autoantigen IA-2 eluted from HLA-DR4. Journal of Clinical Investigation, 104, 1449-1457.
-
(1999)
Journal of Clinical Investigation
, vol.104
, pp. 1449-1457
-
-
Peakman, M.1
Stevens, E.J.2
Lohmann, T.3
Narendran, P.4
Dromey, J.5
Alexander, A.6
Tomlinson, A.J.7
Trucco, M.8
Gorga, J.C.9
Chicz, R.M.10
-
28
-
-
0035142467
-
A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin
-
Alleva, D. G., Crowe, P. D., Jin, L., Kwok, W. W., Ling, N., Gottschalk, M., Conlon, P. J., Gottlieb, P. A., Putnam, A. L., & Gaur, A. (2001). A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin. Journal of Clinical Investigation, 107, 173-180.
-
(2001)
Journal of Clinical Investigation
, vol.107
, pp. 173-180
-
-
Alleva, D.G.1
Crowe, P.D.2
Jin, L.3
Kwok, W.W.4
Ling, N.5
Gottschalk, M.6
Conlon, P.J.7
Gottlieb, P.A.8
Putnam, A.L.9
Gaur, A.10
-
29
-
-
0036212794
-
GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes
-
Viglietta, V., Kent, S. C., Orban, T., & Hafler, D. A. (2002). GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes. Journal of Clinical Investigation, 109, 895-903.
-
(2002)
Journal of Clinical Investigation
, vol.109
, pp. 895-903
-
-
Viglietta, V.1
Kent, S.C.2
Orban, T.3
Hafler, D.A.4
-
30
-
-
0038303191
-
The role of T-cells in the pathogenesis of type 1 diabetes: From cause to cure
-
Roep, B. O. (2003). The role of T-cells in the pathogenesis of type 1 diabetes: From cause to cure. Diabetologia, 46, 305-321.
-
(2003)
Diabetologia
, vol.46
, pp. 305-321
-
-
Roep, B.O.1
-
31
-
-
85047690395
-
Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health
-
Arif, S., Tree, T. I., Astill, T. P., Tremble, J. M., Bishop, A. J., Dayan, C. M., Roep, B. O., & Peakman, M. (2004). Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health. Journal of Clinical Investigation, 113, 451-463.
-
(2004)
Journal of Clinical Investigation
, vol.113
, pp. 451-463
-
-
Arif, S.1
Tree, T.I.2
Astill, T.P.3
Tremble, J.M.4
Bishop, A.J.5
Dayan, C.M.6
Roep, B.O.7
Peakman, M.8
-
32
-
-
3042698353
-
HLA-DQ-regulated T-cell responses to islet cell autoantigens insulin and GAD65
-
Tree, T. I., Duinkerken, G., Willemen, S., de Vries, R. R., & Roep, B. O. (2004). HLA-DQ-regulated T-cell responses to islet cell autoantigens insulin and GAD65. Diabetes, 53, 1692-1699.
-
(2004)
Diabetes
, vol.53
, pp. 1692-1699
-
-
Tree, T.I.1
Duinkerken, G.2
Willemen, S.3
de Vries, R.R.4
Roep, B.O.5
-
33
-
-
0035187182
-
Suppressor T cells - they're back and critical for regulation of autoimmunity!
-
Chatenoud, L., Salomon, B., & Bluestone, J. A. (2001). Suppressor T cells - they're back and critical for regulation of autoimmunity! Immunological Reviews, 182, 149-163.
-
(2001)
Immunological Reviews
, vol.182
, pp. 149-163
-
-
Chatenoud, L.1
Salomon, B.2
Bluestone, J.A.3
-
34
-
-
16844362608
-
Mechanisms of suppression by suppressor T cells
-
von Boehmer, H. (2005). Mechanisms of suppression by suppressor T cells. Nature Immunology, 6, 338-344.
-
(2005)
Nature Immunology
, vol.6
, pp. 338-344
-
-
von Boehmer, H.1
-
35
-
-
16844365788
-
+ regulatory T cells in immunological tolerance to self and non-self
-
+ regulatory T cells in immunological tolerance to self and non-self. Nature Immunology, 6, 345-352.
-
(2005)
Nature Immunology
, vol.6
, pp. 345-352
-
-
Sakaguchi, S.1
-
36
-
-
2442484053
-
+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annual Review of Immunology, 22, 531-562.
-
(2004)
Annual Review of Immunology
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
37
-
-
0031647622
-
+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state. International Immunology, 10, 1969-1980.
-
(1998)
International Immunology
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
Sakaguchi, N.4
Itoh, M.5
Iwata, M.6
Shimizu, J.7
Sakaguchi, S.8
-
39
-
-
0024321866
-
Circulating human T and B lymphocytes express the p55 interleukin-2 receptor molecule (TAC, CD25)
-
Zola, H., Mantzioris, B. X., Webster, J., & Kette, F. E. (1989). Circulating human T and B lymphocytes express the p55 interleukin-2 receptor molecule (TAC, CD25). Immunology and Cell Biology, 67, 233-237.
-
(1989)
Immunology and Cell Biology
, vol.67
, pp. 233-237
-
-
Zola, H.1
Mantzioris, B.X.2
Webster, J.3
Kette, F.E.4
-
40
-
-
0031091743
-
Is CTLA-4 a master switch for peripheral T cell tolerance?
-
Bluestone, J. A. (1997). Is CTLA-4 a master switch for peripheral T cell tolerance? Journal of Immunology, 158, 1989-1993.
-
(1997)
Journal of Immunology
, vol.158
, pp. 1989-1993
-
-
Bluestone, J.A.1
-
41
-
-
0036195161
-
+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity, 16, 311-323.
-
(2002)
Immunity
, vol.16
, pp. 311-323
-
-
McHugh, R.S.1
Whitters, M.J.2
Piccirillo, C.A.3
Young, D.A.4
Shevach, E.M.5
Collins, M.6
Byrne, M.C.7
-
43
-
-
0346103659
-
+T cells controlling distinct organ-specific autoimmune diseases
-
+T cells controlling distinct organ-specific autoimmune diseases. Proceedings of the National Academic Science USA, 100, 15806-15811.
-
(2003)
Proceedings of the National Academic Science USA
, vol.100
, pp. 15806-15811
-
-
Alyanakian, M.A.1
You, S.2
Damotte, D.3
Gouarin, C.4
Esling, A.5
Garcia, C.6
Havouis, S.7
Chatenoud, L.8
Bach, J.F.9
-
44
-
-
0742284032
-
+ T-regulatory cell subset has optimal suppressive and proliferative potential
-
+ T-regulatory cell subset has optimal suppressive and proliferative potential. American Journal of Transplantation, 4, 65-78.
-
(2004)
American Journal of Transplantation
, vol.4
, pp. 65-78
-
-
Fu, S.1
Yopp, A.C.2
Mao, X.3
Chen, D.4
Zhang, N.5
Chen, D.6
Mao, M.7
Ding, Y.8
Bromberg, J.S.9
-
47
-
-
0031821875
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. Journal of Experimental Medicine, 188, 287-296.
-
(1998)
Journal of Experimental Medicine
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
48
-
-
18644365981
-
+) T cells: Evidence from a lymphopenic T cell model
-
+) T cells: Evidence from a lymphopenic T cell model. Immunity, 17, 425-436.
-
(2002)
Immunity
, vol.17
, pp. 425-436
-
-
Bhandoola, A.1
Tai, X.2
Eckhaus, M.3
Auchincloss, H.4
Mason, K.5
Rubin, S.A.6
Carbone, K.M.7
Grossman, Z.8
Rosenberg, A.S.9
Singer, A.10
-
49
-
-
4143066714
-
+ T cell receptors
-
+ T cell receptors. Immunity, 21, 267-277.
-
(2004)
Immunity
, vol.21
, pp. 267-277
-
-
Hsieh, C.S.1
Liang, Y.2
Tyznik, A.J.3
Self, S.G.4
Liggitt, D.5
Rudensky, A.Y.6
-
50
-
-
0029028363
-
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta
-
Suzuki, H., Kundig, T. M., Furlonger, C., Wakeham, A., Timms, E., Matsuyama, T., Schmits, R., Simard, J. J., Ohashi, P. S., & Griesser, H. (1995). Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta. Science, 268, 1472-1476.
-
(1995)
Science
, vol.268
, pp. 1472-1476
-
-
Suzuki, H.1
Kundig, T.M.2
Furlonger, C.3
Wakeham, A.4
Timms, E.5
Matsuyama, T.6
Schmits, R.7
Simard, J.J.8
Ohashi, P.S.9
Griesser, H.10
-
51
-
-
0034654319
-
Normal lymphoid homeostasis and lack of lethal autoimmunity in mice containing mature T cells with severely impaired IL-2 receptors
-
Malek, T. R., Porter, B. O., Codias, E. K., Scibelli, P., & Yu, A. (2000). Normal lymphoid homeostasis and lack of lethal autoimmunity in mice containing mature T cells with severely impaired IL-2 receptors. Journal of Immunology, 164, 2905-2914.
-
(2000)
Journal of Immunology
, vol.164
, pp. 2905-2914
-
-
Malek, T.R.1
Porter, B.O.2
Codias, E.K.3
Scibelli, P.4
Yu, A.5
-
53
-
-
0035871883
-
Stat5a regulates T helper cell differentiation by several distinct mechanisms
-
Kagami, S., Nakajima, H., Suto, A., Hirose, K., Suzuki, K., Morita, S., Kato, I., Saito, Y., Kitamura, T., & Iwamoto, I. (2001). Stat5a regulates T helper cell differentiation by several distinct mechanisms. Blood, 97, 2358-2365.
-
(2001)
Blood
, vol.97
, pp. 2358-2365
-
-
Kagami, S.1
Nakajima, H.2
Suto, A.3
Hirose, K.4
Suzuki, K.5
Morita, S.6
Kato, I.7
Saito, Y.8
Kitamura, T.9
Iwamoto, I.10
-
54
-
-
1542514775
-
Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells
-
Takeda, I., Ine, S., Killeen, N., Ndhlovu, L. C., Murata, K., Satomi, S., Sugamura, K., & Ishii, N. (2004). Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells. Journal of Immunology, 172, 3580-3589.
-
(2004)
Journal of Immunology
, vol.172
, pp. 3580-3589
-
-
Takeda, I.1
Ine, S.2
Killeen, N.3
Ndhlovu, L.C.4
Murata, K.5
Satomi, S.6
Sugamura, K.7
Ishii, N.8
-
55
-
-
0035164360
-
Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: A role of CD40 in regulatory T cell development
-
Kumanogoh, A., Wang, X., Lee, I., Watanabe, C., Kamanaka, M., Shi, W., Yoshida, K., Sato, T., Habu, S., Itoh, M., Sakaguchi, N., Sakaguchi, S., & Kikutani, H. (2001). Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: A role of CD40 in regulatory T cell development. Journal of Immunology, 166, 353-360.
-
(2001)
Journal of Immunology
, vol.166
, pp. 353-360
-
-
Kumanogoh, A.1
Wang, X.2
Lee, I.3
Watanabe, C.4
Kamanaka, M.5
Shi, W.6
Yoshida, K.7
Sato, T.8
Habu, S.9
Itoh, M.10
Sakaguchi, N.11
Sakaguchi, S.12
Kikutani, H.13
-
59
-
-
0348223787
-
+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. Journal of Experimental Medicine, 198, 1875-1886.
-
(2003)
Journal of Experimental Medicine
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
McGrady, G.7
Wahl, S.M.8
-
60
-
-
0042931258
-
+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion
-
+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion. Journal of Immunology, 171, 2270-2278.
-
(2003)
Journal of Immunology
, vol.171
, pp. 2270-2278
-
-
Goudy, K.S.1
Burkhardt, B.R.2
Wasserfall, C.3
Song, S.4
Campbell-Thompson, M.L.5
Brusko, T.6
Powers, M.A.7
Clare-Salzler, M.J.8
Sobel, E.S.9
Ellis, T.M.10
Flotte, T.R.11
Atkinson, M.A.12
-
62
-
-
0037450804
-
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide
-
Caramalho, I., Lopes-Carvalho, T., Ostler, D., Zelenay, S., Haury, M., & Demengeot, J. (2003). Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. Journal of Experimental Medicine, 197, 403-411.
-
(2003)
Journal of Experimental Medicine
, vol.197
, pp. 403-411
-
-
Caramalho, I.1
Lopes-Carvalho, T.2
Ostler, D.3
Zelenay, S.4
Haury, M.5
Demengeot, J.6
-
63
-
-
10844252294
-
+ regulatory cell activation and function by dendritic cells
-
+ regulatory cell activation and function by dendritic cells. International Immunology, 16, 1769-1780.
-
(2004)
International Immunology
, vol.16
, pp. 1769-1780
-
-
Fehervari, Z.1
Sakaguchi, S.2
-
65
-
-
1242317790
-
Molecular aspects of regulatory T cell development
-
Fontenot, J. D., & Rudensky, A. Y. (2004). Molecular aspects of regulatory T cell development. Seminars in Immunology, 16, 73-80.
-
(2004)
Seminars in Immunology
, vol.16
, pp. 73-80
-
-
Fontenot, J.D.1
Rudensky, A.Y.2
-
66
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin, R. S., Ramsdell, F., Peake, J., Faravelli, F., Casanova, J. L., Buist, N., Levy-Lahad, E., Mazzella, M., Goulet, O., Perroni, L., Bricarelli, F. D., Byrne, G., McEuen, M., Proll, S., Appleby, M., & Brunlow, M. E. (2001). X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nature Genetics, 27, 18-20.
-
(2001)
Nature Genetics
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
Ramsdell, F.2
Peake, J.3
Faravelli, F.4
Casanova, J.L.5
Buist, N.6
Levy-Lahad, E.7
Mazzella, M.8
Goulet, O.9
Perroni, L.10
Bricarelli, F.D.11
Byrne, G.12
McEuen, M.13
Proll, S.14
Appleby, M.15
Brunlow, M.E.16
-
67
-
-
0036346861
-
Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome
-
Wildin, R. S., Smyk-Pearson, S., & Filipovich, A. H. (2002). Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome. Journal of Medical Genetics, 39, 537-545.
-
(2002)
Journal of Medical Genetics
, vol.39
, pp. 537-545
-
-
Wildin, R.S.1
Smyk-Pearson, S.2
Filipovich, A.H.3
-
68
-
-
0043246615
-
Rescue of the autoimmune scurfy mouse by partial bone marrow transplantation or by injection with T-enriched splenocytes
-
Smyk-Pearson, S. K., Bakke, A. C., Held, P. K., & Wildin, R. S. (2003). Rescue of the autoimmune scurfy mouse by partial bone marrow transplantation or by injection with T-enriched splenocytes. Clinical and Experimental Immunology, 133, 193-199.
-
(2003)
Clinical and Experimental Immunology
, vol.133
, pp. 193-199
-
-
Smyk-Pearson, S.K.1
Bakke, A.C.2
Held, P.K.3
Wildin, R.S.4
-
69
-
-
0027369395
-
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
-
Sadlack, B., Merz, H., Schorle, H., Schimpl, A., Feller, A. C., & Horak, I. (1993). Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell, 75, 253-261.
-
(1993)
Cell
, vol.75
, pp. 253-261
-
-
Sadlack, B.1
Merz, H.2
Schorle, H.3
Schimpl, A.4
Feller, A.C.5
Horak, I.6
-
70
-
-
0028784289
-
Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
-
Willerford, D. M., Chen, J., Ferry, J. A., Davidson, L., Ma, A., & Alt, F. W. (1995). Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity, 3, 521-530.
-
(1995)
Immunity
, vol.3
, pp. 521-530
-
-
Willerford, D.M.1
Chen, J.2
Ferry, J.A.3
Davidson, L.4
Ma, A.5
Alt, F.W.6
-
71
-
-
0342632839
-
Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo
-
Suzuki, H., Zhou, Y. W., Kato, M., Mak, T. W., & Nakashima, I. (1999). Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo. Journal of Experimental Medicine, 190, 1561-1572.
-
(1999)
Journal of Experimental Medicine
, vol.190
, pp. 1561-1572
-
-
Suzuki, H.1
Zhou, Y.W.2
Kato, M.3
Mak, T.W.4
Nakashima, I.5
-
72
-
-
0037100520
-
Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable
-
Leveen, P., Larsson, J., Ehinger, M., Cilio, C. M., Sundler, M., Sjostrand, L. J., Holmdahl, R., & Karlsson, S. (2002). Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable. Blood, 100, 560-568.
-
(2002)
Blood
, vol.100
, pp. 560-568
-
-
Leveen, P.1
Larsson, J.2
Ehinger, M.3
Cilio, C.M.4
Sundler, M.5
Sjostrand, L.J.6
Holmdahl, R.7
Karlsson, S.8
-
73
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
Waterhouse, P., Penninger, J. M., Timms, E., Wakeham, A., Shahinian, A., Lee, K. P., Thompson, C. B., Griesser, H., & Mak, T. W. (1995). Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science, 270, 985-988.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
Griesser, H.8
Mak, T.W.9
-
74
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett, C. L., Christie, J., Ramsdell, F., Brunkow, M. E., Ferguson, P. J., Whitesell, L., Kelly, T. E., Saulsbury, F. T., Chance, P. F., & Ochs, H. D. (2001). The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nature Genetics, 27, 20-21.
-
(2001)
Nature Genetics
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
Christie, J.2
Ramsdell, F.3
Brunkow, M.E.4
Ferguson, P.J.5
Whitesell, L.6
Kelly, T.E.7
Saulsbury, F.T.8
Chance, P.F.9
Ochs, H.D.10
-
75
-
-
0035576221
-
The amount of scurfin protein determines peripheral T cell number and responsiveness
-
Khattri, R., Kasprowicz, D., Cox, T., Mortrud, M., Appleby, M. W., Brunkow, M. E., Ziegler, S. F., & Ramsdell, F. (2001). The amount of scurfin protein determines peripheral T cell number and responsiveness. Journal of Immunology, 167, 6312-6320.
-
(2001)
Journal of Immunology
, vol.167
, pp. 6312-6320
-
-
Khattri, R.1
Kasprowicz, D.2
Cox, T.3
Mortrud, M.4
Appleby, M.W.5
Brunkow, M.E.6
Ziegler, S.F.7
Ramsdell, F.8
-
77
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., Nomura, T., & Sakaguchi, S. (2003). Control of regulatory T cell development by the transcription factor Foxp3. Science, 299, 1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
78
-
-
0035813231
-
Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation
-
Schubert, L. A., Jeffery, E., Zhang, Y., Ramsdell, F., & Ziegler, S. F. (2001). Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation. Journal of Biological Chemistry, 276, 37672-37679.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 37672-37679
-
-
Schubert, L.A.1
Jeffery, E.2
Zhang, Y.3
Ramsdell, F.4
Ziegler, S.F.5
-
79
-
-
0037866671
-
Fox's in development and disease
-
Lehmann, O. J., Sowden, J. C., Carlsson, P., Jordan, T., & Bhattacharya, S. S. (2003). Fox's in development and disease. Trends Genetics, 19, 339-344.
-
(2003)
Trends Genetics
, vol.19
, pp. 339-344
-
-
Lehmann, O.J.1
Sowden, J.C.2
Carlsson, P.3
Jordan, T.4
Bhattacharya, S.S.5
-
82
-
-
0037099613
-
+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
-
+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. Journal of Experimental Medicine, 196, 237-246.
-
(2002)
Journal of Experimental Medicine
, vol.196
, pp. 237-246
-
-
Piccirillo, C.A.1
Letterio, J.J.2
Thornton, A.M.3
McHugh, R.S.4
Mamura, M.5
Mizuhara, H.6
Shevach, E.M.7
-
83
-
-
0346969978
-
+
-
+. Journal of Clinical Investigation, 112, 1437-1443.
-
(2003)
Journal of Clinical Investigation
, vol.112
, pp. 1437-1443
-
-
Walker, M.R.1
Kasprowicz, D.J.2
Gersuk, V.H.3
Benard, A.4
Van Landeghen, M.5
Buckner, J.H.6
Ziegler, S.F.7
-
84
-
-
9144219649
-
+ T cells
-
+ T cells. Journal of Immunology, 173, 6526-6531.
-
(2004)
Journal of Immunology
, vol.173
, pp. 6526-6531
-
-
Huber, S.1
Schramm, C.2
Lehr, H.A.3
Mann, A.4
Schmitt, S.5
Becker, C.6
Protschka, M.7
Galle, P.R.8
Neurath, M.F.9
Blessing, M.10
-
85
-
-
15444363794
-
+) regulatory T cells
-
+) regulatory T cells. Journal of Experimental Medicine, 201, 737-746.
-
(2005)
Journal of Experimental Medicine
, vol.201
, pp. 737-746
-
-
Fahlen, L.1
Read, S.2
Gorelik, L.3
Hurst, S.D.4
Coffman, R.L.5
Flavell, R.A.6
Powrie, F.7
-
87
-
-
19944369378
-
+ T regulatory cells in humans
-
+ T regulatory cells in humans. Human Immunology, 66, 13-20.
-
(2005)
Human Immunology
, vol.66
, pp. 13-20
-
-
Morgan, M.E.1
van Bilsen, J.H.2
Bakker, A.M.3
Heemskerk, B.4
Schilham, M.W.5
Hartgers, F.C.6
Elferink, B.G.7
van der Zanden, L.8
de Vries, R.R.9
Huizinga, T.W.10
Ottenhoff, T.H.11
Toes, R.E.12
-
88
-
-
12744262844
-
Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes
-
Jaeckel, E., von Boehmer, H., & Manns, M. P. (2005). Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes. Diabetes, 54, 306-310.
-
(2005)
Diabetes
, vol.54
, pp. 306-310
-
-
Jaeckel, E.1
von Boehmer, H.2
Manns, M.P.3
-
89
-
-
0036700341
-
Expression of transgene encoded TGF-beta in islets prevents autoimmune diabetes in NOD mice by a local mechanism
-
Grewal, I. S., Grewal, K. D., Wong, F. S., Wang, H., Picarella, D. E., Janeway Jr., C. A. , & Flavell, R. A. (2002). Expression of transgene encoded TGF-beta in islets prevents autoimmune diabetes in NOD mice by a local mechanism. Journal of Autoimmunology, 19, 9-22.
-
(2002)
Journal of Autoimmunology
, vol.19
, pp. 9-22
-
-
Grewal, I.S.1
Grewal, K.D.2
Wong, F.S.3
Wang, H.4
Picarella, D.E.5
Janeway Jr., C.A.6
Flavell, R.A.7
-
91
-
-
20944444896
-
Autoimmune diabetes onset results from qualitative rather than quantitative age dependent changes in pathogenic T-cells
-
You, S., Belghith, M., Cobbold, S., Alyanakian, M. A., Gouarin, C., Barriot, S., Garcia, C., Waldmann, H., Bach, J. F., & Chatenoud, L. (2005). Autoimmune diabetes onset results from qualitative rather than quantitative age dependent changes in pathogenic T-cells. Diabetes, 54, 1415-1422.
-
(2005)
Diabetes
, vol.54
, pp. 1415-1422
-
-
You, S.1
Belghith, M.2
Cobbold, S.3
Alyanakian, M.A.4
Gouarin, C.5
Barriot, S.6
Garcia, C.7
Waldmann, H.8
Bach, J.F.9
Chatenoud, L.10
-
93
-
-
2442628376
-
+ regulatory T cells in autoimmune polyglandular syndrome Type II
-
+ regulatory T cells in autoimmune polyglandular syndrome Type II. Journal of Experimental Medicine, 199, 1285-1291.
-
(2004)
Journal of Experimental Medicine
, vol.199
, pp. 1285-1291
-
-
Kriegel, M.A.1
Lohmann, T.2
Gabler, C.3
Blank, N.4
Kalden, J.R.5
Lorenz, H.M.6
-
95
-
-
12144249838
-
+) T-cells from patients with type 1 diabetes
-
+) T-cells from patients with type 1 diabetes. Diabetes, 54, 92-99.
-
(2005)
Diabetes
, vol.54
, pp. 92-99
-
-
Lindley, S.1
Dayan, C.M.2
Bishop, A.3
Roep, B.O.4
Peakman, M.5
Tree, T.I.6
-
98
-
-
3042779888
-
No association between variation of the FOXP3 gene and common type 1 diabetes in the Sardinian population
-
Zavattari, P., Deidda, E., Pitzalis, M., Zoa, B., Moi, L., Lampis, R., Contu, D., Motzo, C., Frogia, P., Angius, E., Maioli, M., Todd, J. A., & Cucca, F. (2004). No association between variation of the FOXP3 gene and common type 1 diabetes in the Sardinian population. Diabetes, 53, 1911-1914.
-
(2004)
Diabetes
, vol.53
, pp. 1911-1914
-
-
Zavattari, P.1
Deidda, E.2
Pitzalis, M.3
Zoa, B.4
Moi, L.5
Lampis, R.6
Contu, D.7
Motzo, C.8
Frogia, P.9
Angius, E.10
Maioli, M.11
Todd, J.A.12
Cucca, F.13
-
99
-
-
20244373351
-
Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms
-
Vella, A., Cooper, J. D., Lowe, C. E., Walker, N., Nutland, S., Widmer, B., Jones, R., Ring, S. M., McArdle, W., Pembrey, M. E., Strachan, D. P., Dunger, D. B., Twells, R. C., Clayton, D. G., & Todd, J. A. (2005). Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. American Journal of Human Genetics, 76, 773-779.
-
(2005)
American Journal of Human Genetics
, vol.76
, pp. 773-779
-
-
Vella, A.1
Cooper, J.D.2
Lowe, C.E.3
Walker, N.4
Nutland, S.5
Widmer, B.6
Jones, R.7
Ring, S.M.8
McArdle, W.9
Pembrey, M.E.10
Strachan, D.P.11
Dunger, D.B.12
Twells, R.C.13
Clayton, D.G.14
Todd, J.A.15
-
101
-
-
18144396195
-
+ regulatory T cells suppress effector T cell proliferation
-
+ regulatory T cells suppress effector T cell proliferation. Clinical Immunology, 115, 3-9.
-
(2005)
Clinical Immunology
, vol.115
, pp. 3-9
-
-
Earle, K.E.1
Tang, Q.2
Zhou, X.3
Liu, W.4
Zhu, S.5
Bonyhadi, M.L.6
Bluestone, J.A.7
-
102
-
-
33847373481
-
+ Regulatory T-Cells in Type 1 Diabetes
-
+ Regulatory T-Cells in Type 1 Diabetes. Diabetes, 56(3), 604-612.
-
(2007)
Diabetes
, vol.56
, Issue.3
, pp. 604-612
-
-
Brusko, T.1
Wasserfall, C.2
McGrail, K.3
Schatz, R.4
Viener, H.L.5
Schatz, D.6
Haller, M.7
Rockell, J.8
Gottlieb, P.9
Clare-Salzler, M.10
Atkinson, M.11
-
103
-
-
33745817085
-
+ T reg cells
-
+ T reg cells. Journal ofExperimental Medicine, 203(7), 1701-1711.
-
(2006)
Journal ofExperimental Medicine
, vol.203
, Issue.7
, pp. 1701-1711
-
-
Liu, W.1
Putnam, A.L.2
Xu-Yu, Z.3
Szot, G.L.4
Lee, M.R.5
Zhu, S.6
Gottlieb, P.A.7
Kapranov, P.8
Gingeras, T.R.9
Fazekas de St Groth, B.10
Clayberger, C.11
Soper, D.M.12
Ziegler, S.F.13
Bluestone, J.A.14
-
104
-
-
33845379986
-
+ regulatory T cells of both healthy subjects and type 1 diabetic patients
-
+ regulatory T cells of both healthy subjects and type 1 diabetic patients. Journal of Immunology, 177(12), 8338-8347.
-
(2006)
Journal of Immunology
, vol.177
, Issue.12
, pp. 8338-8347
-
-
Battaglia, M.1
Stabilini, A.2
Migliavacca, B.3
Horejs-Hoeck, J.4
Kaupper, T.5
Roncarolo, M.G.6
|