메뉴 건너뛰기




Volumn 107, Issue 2, 2001, Pages 173-180

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; EPITOPE; GAMMA INTERFERON; HLA ANTIGEN CLASS 2; INSULIN;

EID: 0035142467     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI8525     Document Type: Article
Times cited : (188)

References (34)
  • 2
    • 0031423760 scopus 로고    scopus 로고
    • The nonobese diabetic mouse as a model of autoimmune diabetes: Immune dysregulation gets the NOD
    • erratum 1998, 8:531
    • (1997) Immunity , vol.7 , pp. 727-738
    • Delovitch, T.L.1    Singh, B.2
  • 7
    • 0032823399 scopus 로고    scopus 로고
    • Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library
    • (1999) Nat. Med. , vol.5 , pp. 1026-1031
    • Wong, F.S.1
  • 8
    • 0033553645 scopus 로고    scopus 로고
    • Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells
    • (1999) Science , vol.284 , pp. 1183-1187
    • Yoon, J.W.1
  • 9
    • 0027908753 scopus 로고
    • Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice
    • (1993) Nature , vol.366 , pp. 72-75
    • Tisch, R.1
  • 10
    • 0028584260 scopus 로고
    • Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives
    • (1994) Diabetes , vol.43 , pp. 1304-1310
    • Bingley, P.J.1
  • 11
    • 0028820551 scopus 로고
    • Correlates of insulin autoantibodies with beta cell function at the time of diagnosis of diabetes mellitus
    • (1995) Am.J. Med. Sci. , vol.310 , pp. 138-142
    • Al-Attas, O.S.1
  • 12
    • 0030935082 scopus 로고    scopus 로고
    • Altered immune response to insulin in newly diagnosed compared to insulin-treated diabetic patients and healthy control subjects
    • (1997) Diabetologia , vol.40 , pp. 564-572
    • Schloot, N.C.1
  • 16
    • 0032968699 scopus 로고    scopus 로고
    • Cellular immune responses against proinsulin: No evidence for enhanced reactivity in individuals with IDDM
    • (1999) Diabetes , vol.48 , pp. 299-303
    • Ellis, T.1
  • 17
    • 0031766035 scopus 로고    scopus 로고
    • Autoimmune responses to the beta cell autoantigen, insulin, and the INS VNTR-IDDM2 locus
    • (1998) Clin. Exp. Immunol. , vol.114 , pp. 370-376
    • Sarugeri, E.1
  • 22
    • 0029995958 scopus 로고    scopus 로고
    • Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies
    • (1996) Diabetes , vol.45 , pp. 926-933
    • Verge, C.F.1
  • 28
    • 0030692060 scopus 로고    scopus 로고
    • Biochemical characterization of the human diabetes-associated HLA-DQ8 allelic product: Similarity to the major histocompatibility complex class II I-A(g)7 protein of non-obese diabetic mice
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2478-2483
    • Reizis, B.1    Altmann, D.M.2    Cohen, I.R.3
  • 29
    • 0029360443 scopus 로고
    • Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes
    • (1995) Mol. Med. , vol.1 , pp. 625-633
    • Rudy, G.1
  • 30
    • 0030051666 scopus 로고    scopus 로고
    • HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent-onset insulin-dependent diabetes mellitus
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1285-1289
    • Roep, B.O.1
  • 32
    • 0031025574 scopus 로고    scopus 로고
    • Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice
    • erratum 1997, 46:924
    • (1997) Diabetes , vol.46 , pp. 34-39
    • French, M.B.1
  • 33
    • 0028861576 scopus 로고
    • Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcription
    • (1995) J. Clin. Invest. , vol.95 , pp. 628-634
    • Muir, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.