Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance

Journal of Biological Chemistry

Volumn 282, Issue 22, 2007, Pages 16042-16053

  Medvedev, Andrei E ^a   Piao, Wenji ^a   Shoenfelt, Joanna ^a   Sang, Hoon Rhee ^b   Chen, Haiyan ^a   Basu, Subhendu ^a   Wahl, Larry M ^c   Fenton, Matthew J ^a,d   Vogel, Stefanie N ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; ENZYME ACTIVITY; SIGNAL TRANSDUCTION;

CELL ACTIVATION; ENDOTOXIN TOLERANCE; HUMAN EMBRYONIC KIDNEY; LIPOPOLYSACCHARIDE (LPS);

PHOSPHORYLATION;

4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; CD14 ANTIGEN; CD4 ANTIGEN; ENDOTOXIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE LYN; PROTEIN MD 2; PROTEIN TYROSINE KINASE; RANTES; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TYROSINE; I KAPPA B; LY96 PROTEIN, HUMAN; LYN PROTEIN-TYROSINE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MYD88 PROTEIN, HUMAN; MYELOID DIFFERENTIATION FACTOR 88; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; TLR2 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN; TLR4 PROTEIN, MOUSE; UNCLASSIFIED DRUG;

AGONIST; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CELL STRAIN HEK293; CONTROLLED STUDY; CORRELATION ANALYSIS; EMBRYO; HUMAN; HUMAN CELL; MONOCYTE; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INDUCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; AMINO ACID SUBSTITUTION; ANIMAL; BIOSYNTHESIS; CELL LINE; DRUG EFFECT; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; METABOLISM; MISSENSE MUTATION; PHOSPHORYLATION; PHYSIOLOGY; SEQUENCE HOMOLOGY;

MUS;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIGENS, CD14; CELL LINE; HUMANS; I-KAPPA B PROTEINS; IMMUNE TOLERANCE; LIPOPOLYSACCHARIDES; LYMPHOCYTE ANTIGEN 96; MAP KINASE KINASE 4; MICE; MUTATION, MISSENSE; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 34447525018     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M606781200     Document Type: Article

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