Cutting edge: Expression of IL-1 receptor-associated kinase-4 (IRAK-4) proteins with mutations identified in a patient with recurrent bacterial infections alters normal IRAK-4 interaction with components of the IL-1 receptor complex

Journal of Immunology

Volumn 174, Issue 11, 2005, Pages 6587-6591

  Medvedev, Andrei E ^a   Thomas, Karen ^a   Awomoyi, Agnes ^a   Kuhns, Douglas B ^b   Gallin, John I ^c   Li, Xiaoxia ^d   Vogel, Stefanie N ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b SAIC FREDERICK INC   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; MUTANT PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL INFECTION; CELL STRAIN HEK293; ENZYME ACTIVATION; ENZYME ANALYSIS; GENE MUTATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECURRENT INFECTION;

EID: 18944391904     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.11.6587     Document Type: Article

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