메뉴 건너뛰기




Volumn 169, Issue 9, 2002, Pages 5209-5216

Dysregulation of LPS-induced toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells

Author keywords

[No Author keywords available]

Indexed keywords

DIFFERENTIATION ANTIGEN; ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHOTRANSFERASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

EID: 0036838930     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.9.5209     Document Type: Article
Times cited : (248)

References (67)
  • 1
    • 0033975869 scopus 로고    scopus 로고
    • Innate immune recognition: Mechanisms and pathways
    • Medzhitov, R., and C. Janeway, Jr. 2000. Innate immune recognition: Mechanisms and pathways. Immunol. Rev. 173:89.
    • (2000) Immunol. Rev. , vol.173 , pp. 89
    • Medzhitov, R.1    Janeway C., Jr.2
  • 5
    • 0034723186 scopus 로고    scopus 로고
    • Mouse toll-like receptor 4-MD-2 complex mediates lipopolysaccharidemimetic signal transduction by taxol
    • Kawasaki, K., S. Akashi, R. Shimazu, T. Yoshida, K. Miyake, and M. Nishijima. 2000. Mouse toll-like receptor 4-MD-2 complex mediates lipopolysaccharidemimetic signal transduction by taxol. J. Biol. Chem. 275:2251.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2251
    • Kawasaki, K.1    Akashi, S.2    Shimazu, R.3    Yoshida, T.4    Miyake, K.5    Nishijima, M.6
  • 7
    • 0034650427 scopus 로고    scopus 로고
    • Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
    • Ohashi, K., V. Burkart, S. Flohe, and H. Kolb. 2000. Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J. Immunol. 164:558.
    • (2000) J. Immunol. , vol.164 , pp. 558
    • Ohashi, K.1    Burkart, V.2    Flohe, S.3    Kolb, H.4
  • 8
    • 0033580949 scopus 로고    scopus 로고
    • Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2
    • Schwandner, R., R. Dziarski, H. Wesche, M. Rothe, and C. J. Kirschning. 1999. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2, J. Biol. Chem. 274:17406.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17406
    • Schwandner, R.1    Dziarski, R.2    Wesche, H.3    Rothe, M.4    Kirschning, C.J.5
  • 10
    • 0032716031 scopus 로고    scopus 로고
    • The CD14 ligands lipoarabinomannan and lipopotysaccharide differ in their requirement for Toll-like receptors
    • Means, T. K., E. Lien, A. Yoshimura, S. Wang, D. T. Golenbock, and M. J. Fenton. 1999. The CD14 ligands lipoarabinomannan and lipopotysaccharide differ in their requirement for Toll-like receptors. J. Immunol. 163:6748.
    • (1999) J. Immunol. , vol.163 , pp. 6748
    • Means, T.K.1    Lien, E.2    Yoshimura, A.3    Wang, S.4    Golenbock, D.T.5    Fenton, M.J.6
  • 11
    • 0034650420 scopus 로고    scopus 로고
    • Cutting edge: Preferentially the R-stereoisomet of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway
    • Takeuchi, O., A. Kaufmann, K. Grote, T. Kawai, K. Hoshino, M. Morr, P. F. Muhlradt, and S. Akira. 2000. Cutting edge: Preferentially the R-stereoisomet of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway. J. Immunol. 164:554.
    • (2000) J. Immunol. , vol.164 , pp. 554
    • Takeuchi, O.1    Kaufmann, A.2    Grote, K.3    Kawai, T.4    Hoshino, K.5    Morr, M.6    Muhlradt, P.F.7    Akira, S.8
  • 12
    • 0037177825 scopus 로고    scopus 로고
    • Novel signal transduction pathway utilized by extracellular HSP70: Role of toll-like receptor (TLR) 2 and TLR4
    • Asea, A., M. Rehli, E. Kabingu, J. A. Boch, O. Bare, P. E. Auron, M. A. Stevenson, and S. K. Calderwood. 2002. Novel signal transduction pathway utilized by extracellular HSP70: Role of toll-like receptor (TLR) 2 and TLR4. J. Biol. Chem. 277:15028.
    • (2002) J. Biol. Chem. , vol.277 , pp. 15028
    • Asea, A.1    Rehli, M.2    Kabingu, E.3    Boch, J.A.4    Bare, O.5    Auron, P.E.6    Stevenson, M.A.7    Calderwood, S.K.8
  • 13
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
    • Alexopoulou, L., A. C. Holt, R. Medzhitov, and R. A. Flavell. 2001. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413:732.
    • (2001) Nature , vol.413 , pp. 732
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 16
    • 0034623798 scopus 로고    scopus 로고
    • Structure and function of Toll-like receptor proteins
    • Means, T. K., D. T. Golenbock, and M. J. Fenton. 2000. Structure and function of Toll-like receptor proteins. Life Sci. 68:241.
    • (2000) Life Sci. , vol.68 , pp. 241
    • Means, T.K.1    Golenbock, D.T.2    Fenton, M.J.3
  • 17
    • 0033532629 scopus 로고    scopus 로고
    • MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
    • Shimazu, R., S. Akashi, H. Ogata, Y. Nagai, K. Fukudome, K. Miyake, and M. Kimoto. 1999. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189:1777.
    • (1999) J. Exp. Med. , vol.189 , pp. 1777
    • Shimazu, R.1    Akashi, S.2    Ogata, H.3    Nagai, Y.4    Fukudome, K.5    Miyake, K.6    Kimoto, M.7
  • 18
    • 0035555301 scopus 로고    scopus 로고
    • TIRAP: An adapter molecule in the Toll signaling pathway
    • Horng, T., G. M. Barton, and R. Medzhitov. 2001. TIRAP: An adapter molecule in the Toll signaling pathway. Nat. Immunol. 2:835.
    • (2001) Nat. Immunol. , vol.2 , pp. 835
    • Horng, T.1    Barton, G.M.2    Medzhitov, R.3
  • 20
    • 0035889228 scopus 로고    scopus 로고
    • Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
    • Kawai, T., O. Takeuchi, T. Fujita, J. Inoue, P. F. Muhlradt, S. Sato, K. Hoshino, and S. Akira. 2001. Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J. Immunol. 167:5887.
    • (2001) J. Immunol. , vol.167 , pp. 5887
    • Kawai, T.1    Takeuchi, O.2    Fujita, T.3    Inoue, J.4    Muhlradt, P.F.5    Sato, S.6    Hoshino, K.7    Akira, S.8
  • 21
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • Kawai, T., O. Adachi, T. Ogawa, K. Takeda, and S. Akira. 1999. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11:115.
    • (1999) Immunity , vol.11 , pp. 115
    • Kawai, T.1    Adachi, O.2    Ogawa, T.3    Takeda, K.4    Akira, S.5
  • 22
    • 0035339861 scopus 로고    scopus 로고
    • Endotoxin-induced maturation of MyD88-deficient dendritic cells
    • Kaisho, T., O. Takeuchi, T. Kawai, K. Hoshino, and S. Akira. 2001. Endotoxin-induced maturation of MyD88-deficient dendritic cells. J. Immunol. 166:5688.
    • (2001) J. Immunol. , vol.166 , pp. 5688
    • Kaisho, T.1    Takeuchi, O.2    Kawai, T.3    Hoshino, K.4    Akira, S.5
  • 25
    • 0035165287 scopus 로고    scopus 로고
    • Cutting edge: Functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenolsoluble modulin
    • Hajjar, A. M., D. S. O'Mahony, A. Ozinsky, D. M. Underhill, A. Aderem, S. J. Klebanoff, and C. B. Wilson. 2001. Cutting edge: Functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenolsoluble modulin. J. Immunol. 166:15.
    • (2001) J. Immunol. , vol.166 , pp. 15
    • Hajjar, A.M.1    O'Mahony, D.S.2    Ozinsky, A.3    Underhill, D.M.4    Aderem, A.5    Klebanoff, S.J.6    Wilson, C.B.7
  • 26
    • 0031821430 scopus 로고    scopus 로고
    • Molecular basis of endotoxin tolerance
    • Cook, J. A. 1998. Molecular basis of endotoxin tolerance. Ann. NY Acad. Sci. 851:426.
    • (1998) Ann. NY Acad. Sci. , vol.851 , pp. 426
    • Cook, J.A.1
  • 27
    • 0027476016 scopus 로고
    • Gram-negative sepsis: A dilemma of modem medicine
    • Bone, R. C. 1993. Gram-negative sepsis: A dilemma of modem medicine. Clin. Microbiol. Rev. 6:57.
    • (1993) Clin. Microbiol. Rev. , vol.6 , pp. 57
    • Bone, R.C.1
  • 29
    • 20244384395 scopus 로고    scopus 로고
    • Cutting edge: Endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface Toll-like receptor 4 expression
    • Nomura, F., S. Akashi, Y. Sakao, S. Sato, T. Kawai, M. Matsumoto, K. Nakanishi, M. Kimoto, K. Miyake, K. Takeda, et al. 2000. Cutting edge: Endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface Toll-like receptor 4 expression. J. Immunol. 164:3476.
    • (2000) J. Immunol. , vol.164 , pp. 3476
    • Nomura, F.1    Akashi, S.2    Sakao, Y.3    Sato, S.4    Kawai, T.5    Matsumoto, M.6    Nakanishi, K.7    Kimoto, M.8    Miyake, K.9    Takeda, K.10
  • 30
    • 0035881949 scopus 로고    scopus 로고
    • Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4
    • Medvedev, A. E., P. Henneke, A. Schromm, E. Lien, R. Ingalls, M. J. Fenton, D. T. Golenbock, and S. N. Vogel. 2001. Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4. J. Immunol. 167:2257.
    • (2001) J. Immunol , vol.167 , pp. 2257
    • Medvedev, A.E.1    Henneke, P.2    Schromm, A.3    Lien, E.4    Ingalls, R.5    Fenton, M.J.6    Golenbock, D.T.7    Vogel, S.N.8
  • 31
    • 0034725584 scopus 로고    scopus 로고
    • Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells
    • Li, L., S. Cousart, J. Hu, and C. E. McCall. 2000. Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells. J. Biol. Chem. 275:23340.
    • (2000) J. Biol. Chem. , vol.275 , pp. 23340
    • Li, L.1    Cousart, S.2    Hu, J.3    McCall, C.E.4
  • 32
    • 0037151080 scopus 로고    scopus 로고
    • Gram-negative flagellin-induced self-tolerance is associated with a block in IRAK release from TLR5
    • Mizel S. B., and J. A. Snipes. 2002. Gram-negative flagellin-induced self-tolerance is associated with a block in IRAK release from TLR5. J. Biol. Chem. 277:22414.
    • (2002) J. Biol. Chem. , vol.277 , pp. 22414
    • Mizel, S.B.1    Snipes, J.A.2
  • 33
    • 0035871626 scopus 로고    scopus 로고
    • Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators
    • Lehner, M. D., S. Morath, K. S. Michelsen, R. R. Schumann, and T. Hartung. 2001. Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. J. Immunol. 166:5161.
    • (2001) J. Immunol. , vol.166 , pp. 5161
    • Lehner, M.D.1    Morath, S.2    Michelsen, K.S.3    Schumann, R.R.4    Hartung, T.5
  • 34
    • 0014122519 scopus 로고
    • Chemical, physical, and biological properties of a lipopolysaccharide from Escherichia coli K235
    • McIntire, F. C., H. W. Sievert, G. H. Barlow, R. A. Finley, and A. Y. Lee. 1967. Chemical, physical, and biological properties of a lipopolysaccharide from Escherichia coli K235. Biochemistry 6:2363.
    • (1967) Biochemistry , vol.6 , pp. 2363
    • McIntire, F.C.1    Sievert, H.W.2    Barlow, G.H.3    Finley, R.A.4    Lee, A.Y.5
  • 35
    • 0034043956 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: Dysregulation of cytokine, chemokine, and Toll-like receptor 2 and 4 gene expression
    • Medvedev, A. E., K. M. Kopydlowski, and S. N. Vogel. 2000. Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: Dysregulation of cytokine, chemokine, and Toll-like receptor 2 and 4 gene expression. J. Immunol. 164:5564.
    • (2000) J. Immunol. , vol.164 , pp. 5564
    • Medvedev, A.E.1    Kopydlowski, K.M.2    Vogel, S.N.3
  • 36
    • 0033564270 scopus 로고    scopus 로고
    • Use of a photoactivatable taxol analogue to identify unique cellular targets in murine macrophages: Identification of murine CD18 as a major taxol-binding protein and a role for Mac-1 in taxol-induced gene expression
    • Bhat, N., P. Y. Perera, J. M. Carboni, J. Blanco, D. T. Golenbock, T. N. Mayadas, and S. N. Vogel. 1999. Use of a photoactivatable taxol analogue to identify unique cellular targets in murine macrophages: Identification of murine CD18 as a major taxol-binding protein and a role for Mac-1 in taxol-induced gene expression. J. Immunol. 162:7335.
    • (1999) J. Immunol. , vol.162 , pp. 7335
    • Bhat, N.1    Perera, P.Y.2    Carboni, J.M.3    Blanco, J.4    Golenbock, D.T.5    Mayadas, T.N.6    Vogel, S.N.7
  • 37
    • 0027227678 scopus 로고
    • Lipopolysaccharide antagonists block taxol-induced signaling in murine macrophages
    • Manthey, C. L., N. Qureshi, P. L. Stutz, and S. N. Vogel. 1993. Lipopolysaccharide antagonists block taxol-induced signaling in murine macrophages. J. Exp. Med. 178:695.
    • (1993) J. Exp. Med. , vol.178 , pp. 695
    • Manthey, C.L.1    Qureshi, N.2    Stutz, P.L.3    Vogel, S.N.4
  • 38
    • 0034651729 scopus 로고    scopus 로고
    • Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide
    • Flo, T. H., O. Halaas, E. Lien, L. Ryan, G. Teti, D. T. Golenbock, A. Sundan, and T. Espevik. 2000. Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. J. Immunol. 164:2064.
    • (2000) J. Immunol. , vol.164 , pp. 2064
    • Flo, T.H.1    Halaas, O.2    Lien, E.3    Ryan, L.4    Teti, G.5    Golenbock, D.T.6    Sundan, A.7    Espevik, T.8
  • 39
    • 0033382423 scopus 로고    scopus 로고
    • Analysis of Tlr4-mediated LPS signal transduction in macrophages by mutational modification of the receptor
    • Du, X., A. Poltorak, M. Silva, and B. Beutler. 1999. Analysis of Tlr4-mediated LPS signal transduction in macrophages by mutational modification of the receptor. Blood Cells Mol. Dis. 25:328.
    • (1999) Blood Cells Mol. Dis. , vol.25 , pp. 328
    • Du, X.1    Poltorak, A.2    Silva, M.3    Beutler, B.4
  • 41
    • 0031423761 scopus 로고    scopus 로고
    • MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
    • Wesche, H., W. J. Henzel, W. Shillinglaw, S. Li, and Z. Cao. 1997. MyD88: An adapter that recruits IRAK to the IL-1 receptor complex. Immunity 7:837.
    • (1997) Immunity , vol.7 , pp. 837
    • Wesche, H.1    Henzel, W.J.2    Shillinglaw, W.3    Li, S.4    Cao, Z.5
  • 42
    • 0030694108 scopus 로고    scopus 로고
    • IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
    • Muzio, M., J. Ni, P. Feng, and V. M. Dixit. 1997. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 278:1612.
    • (1997) Science , vol.278 , pp. 1612
    • Muzio, M.1    Ni, J.2    Feng, P.3    Dixit, V.M.4
  • 43
    • 0033002994 scopus 로고    scopus 로고
    • Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase
    • Li, X., M. Commane, C. Burns, K. Vithalani, Z. Cao, and G. R. Stark. 1999. Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase. Mol. Cell. Biol. 19:4643.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4643
    • Li, X.1    Commane, M.2    Burns, C.3    Vithalani, K.4    Cao, Z.5    Stark, G.R.6
  • 44
    • 0035500281 scopus 로고    scopus 로고
    • Differential induction of endotoxin tolerance by lipopolysaccharides derived from Porphyromonas gingivalis and Escherichia coli
    • Martin, M., J. Katz, S. N. Vogel, and S. M. Michalek. 2001. Differential induction of endotoxin tolerance by lipopolysaccharides derived from Porphyromonas gingivalis and Escherichia coli. J. Immunol. 167:5278.
    • (2001) J. Immunol. , vol.167 , pp. 5278
    • Martin, M.1    Katz, J.2    Vogel, S.N.3    Michalek, S.M.4
  • 45
    • 0036565888 scopus 로고    scopus 로고
    • Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-γ: A molecular basis for priming and synergism with bacterial lipopolysaccharide
    • Bosisio, D., N. Polentarutti, M. Sironi, S. Bemasconi, K. Miyake, G. R. Webb, M. U. Martin, A. Mantovani, and M. Muzio. 2002. Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-γ: A molecular basis for priming and synergism with bacterial lipopolysaccharide. Blood 99:3427.
    • (2002) Blood , vol.99 , pp. 3427
    • Bosisio, D.1    Polentarutti, N.2    Sironi, M.3    Bemasconi, S.4    Miyake, K.5    Webb, G.R.6    Martin, M.U.7    Mantovani, A.8    Muzio, M.9
  • 46
    • 0037080024 scopus 로고    scopus 로고
    • Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
    • Zarember, K. A., and P. J. Godowski. 2002. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J. Immunol. 168:554.
    • (2002) J. Immunol. , vol.168 , pp. 554
    • Zarember, K.A.1    Godowski, P.J.2
  • 49
    • 0036467357 scopus 로고    scopus 로고
    • In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-γ and TNF-α mediated up-regulation during inflammation
    • Wolfs, T. G., W. A. Buurman, A. van Schadewijk, B. de Vries, M. A. Daemen, P. S. Hiemstra, and C. van't Veer. 2002. In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-γ and TNF-α mediated up-regulation during inflammation. J. Immunol. 168:1286.
    • (2002) J. Immunol. , vol.168 , pp. 1286
    • Wolfs, T.G.1    Buurman, W.A.2    Van Schadewijk, A.3    De Vries, B.4    Daemen, M.A.5    Hiemstra, P.S.6    Van't Veer, C.7
  • 50
    • 0037018107 scopus 로고    scopus 로고
    • Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells
    • Hornef, M. W., T. Frisan, A. Vandewalle, S. Normark, and A. Richter-Dahlfors. 2002. Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells. J. Exp. Med. 195:559.
    • (2002) J. Exp. Med. , vol.195 , pp. 559
    • Hornef, M.W.1    Frisan, T.2    Vandewalle, A.3    Normark, S.4    Richter-Dahlfors, A.5
  • 51
    • 0035253370 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide and IFN-γ induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: Role of NF-κB activation
    • Faure, E., L. Thomas, H. Xu, A. Medvedev, O. Equils, and M. Arditi. 2001. Bacterial lipopolysaccharide and IFN-γ induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: Role of NF-κB activation. J. Immunol. 166:2018.
    • (2001) J. Immunol. , vol.166 , pp. 2018
    • Faure, E.1    Thomas, L.2    Xu, H.3    Medvedev, A.4    Equils, O.5    Arditi, M.6
  • 53
    • 0033779915 scopus 로고    scopus 로고
    • Endotoxin and cytokine regulation of toll-like receptor (TLR) 2 and TLR4 gene expression in murine liver and hepatocytes
    • Matsumura, T., A. Ito, T. Takii, H. Hayashi, and K. Onozaki. 2000. Endotoxin and cytokine regulation of toll-like receptor (TLR) 2 and TLR4 gene expression in murine liver and hepatocytes. J. Interferon Cytokine Res. 20:915.
    • (2000) J. Interferon Cytokine Res. , vol.20 , pp. 915
    • Matsumura, T.1    Ito, A.2    Takii, T.3    Hayashi, H.4    Onozaki, K.5
  • 54
    • 0034670047 scopus 로고    scopus 로고
    • Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages
    • Matsuguchi, T., T. Musikacharoen, T. Ogawa, and Y. Yoshikai. 2000. Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages. J. Immunol. 165:5767.
    • (2000) J. Immunol. , vol.165 , pp. 5767
    • Matsuguchi, T.1    Musikacharoen, T.2    Ogawa, T.3    Yoshikai, Y.4
  • 57
    • 0033564325 scopus 로고    scopus 로고
    • Cutting edge: Cells that carry A null allele for Toll-like receptor 2 are capable of responding to endotoxin
    • Heine, H., C. J. Kirschning, E. Lien, B. G. Monks, M. Rothe, and D. T. Golenbock. 1999. Cutting edge: Cells that carry A null allele for Toll-like receptor 2 are capable of responding to endotoxin. J. Immunol. 162:6971.
    • (1999) J. Immunol. , vol.162 , pp. 6971
    • Heine, H.1    Kirschning, C.J.2    Lien, E.3    Monks, B.G.4    Rothe, M.5    Golenbock, D.T.6
  • 58
    • 0033567388 scopus 로고    scopus 로고
    • ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway
    • Kopp, E., R. Medzhitov, J. Carothers, C. Xiao, I. Douglas, C. A. Janeway, and S. Ghosh. 1999. ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes Dev. 13:2059.
    • (1999) Genes Dev. , vol.13 , pp. 2059
    • Kopp, E.1    Medzhitov, R.2    Carothers, J.3    Xiao, C.4    Douglas, I.5    Janeway, C.A.6    Ghosh, S.7
  • 59
    • 0034008927 scopus 로고    scopus 로고
    • Transcriptional activation of the cyclooxygenase-2 gene in endotoxin-treated RAW 264.7 macrophages
    • Wadleigh, D. J., S. T. Reddy, E. Kopp, S. Ghosh, and H. R. Herschman. 2000. Transcriptional activation of the cyclooxygenase-2 gene in endotoxin-treated RAW 264.7 macrophages. J. Biol. Chem. 275:6259.
    • (2000) J. Biol. Chem. , vol.275 , pp. 6259
    • Wadleigh, D.J.1    Reddy, S.T.2    Kopp, E.3    Ghosh, S.4    Herschman, H.R.5
  • 60
    • 0033583034 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes
    • Zhang, F. X., C. J. Kirschning, R. Mancinelli, X. P. Xu, Y. Jin, E. Faure, A. Mantovani, M. Rothe, M. Muzio, and M. Arditi. 1999. Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J. Biol. Chem. 274:7611.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7611
    • Zhang, F.X.1    Kirschning, C.J.2    Mancinelli, R.3    Xu, X.P.4    Jin, Y.5    Faure, E.6    Mantovani, A.7    Rothe, M.8    Muzio, M.9    Arditi, M.10
  • 62
    • 0035885127 scopus 로고    scopus 로고
    • 114 of human MD-2 are required for Toll-like receptor 4-mediated activation of NF-κB by lipopolysaccharide
    • 114 of human MD-2 are required for Toll-like receptor 4-mediated activation of NF-κB by lipopolysaccharide. J. Immunol. 167:3354.
    • (2001) J. Immunol. , vol.167 , pp. 3354
    • Ohnishi, T.1    Muroi, M.2    Tanamoto, K.3
  • 63
    • 0037127309 scopus 로고    scopus 로고
    • MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor
    • da Silva Correia, J., and R. J. Ulevitch. 2002. MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor. J. Biol. Chem. 277:1845.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1845
    • Da Silva Correia, J.1    Ulevitch, R.J.2
  • 64
    • 0036006290 scopus 로고    scopus 로고
    • Regulation of interleukin-1- and lipopolysaccharide-induced NF-κB activation by alternative splicing of MyD88
    • Janssens, S., K. Burns, J. Tschopp, and R. Beyaert. 2002. Regulation of interleukin-1- and lipopolysaccharide-induced NF-κB activation by alternative splicing of MyD88. Curr. Biol. 12:467.
    • (2002) Curr. Biol. , vol.12 , pp. 467
    • Janssens, S.1    Burns, K.2    Tschopp, J.3    Beyaert, R.4
  • 66
    • 0036510366 scopus 로고    scopus 로고
    • Negative regulation of toll-like receptor-mediated signaling by Tollip
    • Zhang, G., and S. Ghosh. 2002. Negative regulation of toll-like receptor-mediated signaling by Tollip. J. Biol. Chem. 277:7059.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7059
    • Zhang, G.1    Ghosh, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.