-
1
-
-
0031905311
-
A family of human receptors structurally related to Drosophila Toll
-
Rock, F. L., G. Hardiman, J. C. Timans, R. A. Kastelein, and J. F. Bazan. 1998. A family of human receptors structurally related to Drosophila Toll. Proc. Natl. Acad. Sci. USA 95: 588-593.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 588-593
-
-
Rock, F.L.1
Hardiman, G.2
Timans, J.C.3
Kastelein, R.A.4
Bazan, J.F.5
-
2
-
-
0038202219
-
Toll-like receptor 4 signalling: New perspectives on a complex signal-transduction problem
-
Vogel, S. N., and M. Fenton. 2003. Toll-like receptor 4 signalling: new perspectives on a complex signal-transduction problem. Biochem. Soc. Trans. 31: 664-668.
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 664-668
-
-
Vogel, S.N.1
Fenton, M.2
-
3
-
-
0035115080
-
Signaling by Toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages
-
Hirschfeld, M., J. J. Weis, V. Toshchakov, C. A. Salkowski, M. J. Cody, D. C. Ward, N. Qureshi, S. M. Michalek, and S. N. Vogel. 2001. Signaling by Toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages. Infect. Immun. 69: 1477-1482.
-
(2001)
Infect. Immun.
, vol.69
, pp. 1477-1482
-
-
Hirschfeld, M.1
Weis, J.J.2
Toshchakov, V.3
Salkowski, C.A.4
Cody, M.J.5
Ward, D.C.6
Qureshi, N.7
Michalek, S.M.8
Vogel, S.N.9
-
4
-
-
0033574415
-
Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
-
Chow, J. C., D. W. Young, D. T. Golenbock, W. J. Christ, and F. Gusovsky. 1999. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J. Biol. Chem. 274: 10689-10692.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10689-10692
-
-
Chow, J.C.1
Young, D.W.2
Golenbock, D.T.3
Christ, W.J.4
Gusovsky, F.5
-
5
-
-
5944261457
-
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
-
Kurt-Jones, E. A., L. Popova, L. Kwinn, L. M. Haynes, L. P. Jones, R. A. Tripp, E. E. Walsh, M. W. Freeman, D. T. Golenbock, L. J. Anderson, and R. W. Finberg. 2000. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat. Immunol. 1: 398-401.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 398-401
-
-
Kurt-Jones, E.A.1
Popova, L.2
Kwinn, L.3
Haynes, L.M.4
Jones, L.P.5
Tripp, R.A.6
Walsh, E.E.7
Freeman, M.W.8
Golenbock, D.T.9
Anderson, L.J.10
Finberg, R.W.11
-
6
-
-
0036467447
-
Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway
-
Bulut, Y., E. Faure, L. Thomas, H. Karahashi, K. S. Michelsen, O. Equils, S. G. Morrison, R. P. Morrison, and M. Arditi. 2002. Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway. J. Immunol. 168: 1435-1440.
-
(2002)
J. Immunol.
, vol.168
, pp. 1435-1440
-
-
Bulut, Y.1
Faure, E.2
Thomas, L.3
Karahashi, H.4
Michelsen, K.S.5
Equils, O.6
Morrison, S.G.7
Morrison, R.P.8
Arditi, M.9
-
7
-
-
0035451118
-
Fibrinogen stimulates macrophage chemokine secretion through Toll-like receptor 4
-
Smiley, S. T., J. A. King, and W. W. Hancock. 2001. Fibrinogen stimulates macrophage chemokine secretion through Toll-like receptor 4. J. Immunol. 167: 2887-2894.
-
(2001)
J. Immunol.
, vol.167
, pp. 2887-2894
-
-
Smiley, S.T.1
King, J.A.2
Hancock, W.W.3
-
9
-
-
0035971217
-
The extra domain A of fibronectin activates Toll-like receptor 4
-
Okamura, Y., M. Watari, E. S. Jerud, D. W. Young, S. T. Ishizaka, J. Rose, J. C. Chow, and J. F. Strauss III. 2001. The extra domain A of fibronectin activates Toll-like receptor 4. J. Biol. Chem. 276: 10229-10233.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10229-10233
-
-
Okamura, Y.1
Watari, M.2
Jerud, E.S.3
Young, D.W.4
Ishizaka, S.T.5
Rose, J.6
Chow, J.C.7
Strauss III, J.F.8
-
10
-
-
0034650427
-
Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the Toll-like receptor-4 complex
-
Ohashi, K., V. Burkart, S. Flohe, and H. Kolb. 2000. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the Toll-like receptor-4 complex. J. Immunol. 164: 558-561.
-
(2000)
J. Immunol.
, vol.164
, pp. 558-561
-
-
Ohashi, K.1
Burkart, V.2
Flohe, S.3
Kolb, H.4
-
11
-
-
0035903158
-
Endocytosed HSP60s use Toll-like receptor 2 (TLR2) and TLR4 to activate the Toll/interleukin-1 receptor signaling pathway in innate immune cells
-
Vabulas, R. M., P. Ahmad-Nejad, C. da Costa, T. Miethke, C. J. Kirschning, H. Hacker, and H. Wagner. 2001. Endocytosed HSP60s use Toll-like receptor 2 (TLR2) and TLR4 to activate the Toll/interleukin-1 receptor signaling pathway in innate immune cells. J. Biol. Chem. 276: 31332-31339.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31332-31339
-
-
Vabulas, R.M.1
Ahmad-Nejad, P.2
Da Costa, C.3
Miethke, T.4
Kirschning, C.J.5
Hacker, H.6
Wagner, H.7
-
12
-
-
0037033364
-
Oligosaccharides of hyaluronan activate dendritic cells via Toll-like receptor 4
-
Termeer, C., F. Benedix, J. Sleeman, C. Fieber, U. Voith, T. Ahrens, K. Miyake, M. Freudenberg, C. Galanos, and J. C. Simon. 2002. Oligosaccharides of hyaluronan activate dendritic cells via Toll-like receptor 4. J. Exp. Med. 195: 99-111.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 99-111
-
-
Termeer, C.1
Benedix, F.2
Sleeman, J.3
Fieber, C.4
Voith, U.5
Ahrens, T.6
Miyake, K.7
Freudenberg, M.8
Galanos, C.9
Simon, J.C.10
-
13
-
-
30744462300
-
Regulation of lung injury and repair by Toll-like receptors and hyaluronan
-
Jiang, D., J. Liang, J. Fan, S. Yu, S. Chen, Y. Luo, G. D. Prestwich, M. M. Mascarenhas, H. G. Garg, D. A. Quinn, et al. 2005. Regulation of lung injury and repair by Toll-like receptors and hyaluronan. Nat. Med. 11: 1173-1179.
-
(2005)
Nat. Med.
, vol.11
, pp. 1173-1179
-
-
Jiang, D.1
Liang, J.2
Fan, J.3
Yu, S.4
Chen, S.5
Luo, Y.6
Prestwich, G.D.7
Mascarenhas, M.M.8
Garg, H.G.9
Quinn, D.A.10
-
14
-
-
0037097672
-
Cutting edge: The immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4
-
Guillot, L., V. Balloy, F. X. McCormack, D. T. Golenbock, M. Chignard, and M. Si-Tahar. 2002. Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4. J. Immunol. 168: 5989-5992.
-
(2002)
J. Immunol.
, vol.168
, pp. 5989-5992
-
-
Guillot, L.1
Balloy, V.2
McCormack, F.X.3
Golenbock, D.T.4
Chignard, M.5
Si-Tahar, M.6
-
15
-
-
4344627821
-
Endogenous ligands of Toll-like receptors
-
Tsan, M. F., and B. Gao. 2004. Endogenous ligands of Toll-like receptors. J. Leukocyte Biol. 76: 514-519.
-
(2004)
J. Leukocyte Biol.
, vol.76
, pp. 514-519
-
-
Tsan, M.F.1
Gao, B.2
-
16
-
-
0033532629
-
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
-
Shimazu, R., S. Akashi, H. Ogata, Y. Nagai, K. Fukudome, K. Miyake, and M. Kimoto. 1999. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189: 1777-1782.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1777-1782
-
-
Shimazu, R.1
Akashi, S.2
Ogata, H.3
Nagai, Y.4
Fukudome, K.5
Miyake, K.6
Kimoto, M.7
-
17
-
-
0035959590
-
Parameters influencing membrane CD14 expression and soluble CD14 levels in sepsis
-
Gluck, T., J. Silver, M. Epstein, P. Cao, B. Farber, and S. M. Goyert. 2001. Parameters influencing membrane CD14 expression and soluble CD14 levels in sepsis. Eur. J. Med. Res. 6: 351-358.
-
(2001)
Eur. J. Med. Res.
, vol.6
, pp. 351-358
-
-
Gluck, T.1
Silver, J.2
Epstein, M.3
Cao, P.4
Farber, B.5
Goyert, S.M.6
-
18
-
-
0031137733
-
CD14-dependent and CD14-independent signaling pathways in murine macrophages from normal and CD14 knockout mice stimulated with lipopolysaccharide or Taxol
-
Perera, P. Y., S. N. Vogel, G. R. Detore, A. Haziot, and S. M. Goyert. 1997. CD14-dependent and CD14-independent signaling pathways in murine macrophages from normal and CD14 knockout mice stimulated with lipopolysaccharide or Taxol. J. Immunol. 158: 4422-4429.
-
(1997)
J. Immunol.
, vol.158
, pp. 4422-4429
-
-
Perera, P.Y.1
Vogel, S.N.2
Detore, G.R.3
Haziot, A.4
Goyert, S.M.5
-
19
-
-
0031030348
-
Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids
-
Yu, B., E. Hailman, and S. D. Wright. 1997. Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids. J. Clin. Invest. 99: 315-324.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 315-324
-
-
Yu, B.1
Hailman, E.2
Wright, S.D.3
-
20
-
-
0034820507
-
Bacterial lipopolysaccharides and innate immunity
-
Alexander, C., and E. T. Rietschel. 2001. Bacterial lipopolysaccharides and innate immunity. J. Endotoxin Res. 7: 167-202.
-
(2001)
J. Endotoxin Res.
, vol.7
, pp. 167-202
-
-
Alexander, C.1
Rietschel, E.T.2
-
21
-
-
0034084438
-
TLR4 mutations ate associated with endotoxin hyporesponsiveness in humans
-
Arbour, N. C., E. Lorenz, B. C. Schutte, J. Zabner, J. N. Kline, M. Jones, K. Frees, J. L. Watt, and D. A. Schwartz. 2000. TLR4 mutations ate associated with endotoxin hyporesponsiveness in humans. Nat. Genet. 25: 187-191.
-
(2000)
Nat. Genet.
, vol.25
, pp. 187-191
-
-
Arbour, N.C.1
Lorenz, E.2
Schutte, B.C.3
Zabner, J.4
Kline, J.N.5
Jones, M.6
Frees, K.7
Watt, J.L.8
Schwartz, D.A.9
-
22
-
-
0042838312
-
Haplotype variation in bovine Toll-like receptor 4 and computational prediction of a positively selected ligand-binding domain
-
White, S. N., K. H. Taylor, C. A. Abbey, C. A. Gill, and J. E. Womack. 2003. Haplotype variation in bovine Toll-like receptor 4 and computational prediction of a positively selected ligand-binding domain. Proc. Natl. Acad. Sci. USA 100: 10364-10369.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10364-10369
-
-
White, S.N.1
Taylor, K.H.2
Abbey, C.A.3
Gill, C.A.4
Womack, J.E.5
-
23
-
-
0141559415
-
Leucine-rich repeats and pathogen recognition in Toll-like receptors
-
Bell, J. K., G. E. Mullen, C. A. Leifer, A. Mazzoni, D. R. Davies, and D. M. Segal. 2003. Leucine-rich repeats and pathogen recognition in Toll-like receptors. Trends Immunol. 24: 528-533.
-
(2003)
Trends Immunol.
, vol.24
, pp. 528-533
-
-
Bell, J.K.1
Mullen, G.E.2
Leifer, C.A.3
Mazzoni, A.4
Davies, D.R.5
Segal, D.M.6
-
24
-
-
0037071251
-
Relevance of mutations in the TLR4 receptor in patients with Gram-negative septic shock
-
Lorenz, E., J. P. Mira, K. L. Frees, and D. A. Schwartz. 2002. Relevance of mutations in the TLR4 receptor in patients with Gram-negative septic shock. Arch. Intern. Med. 162: 1028-1032.
-
(2002)
Arch. Intern. Med.
, vol.162
, pp. 1028-1032
-
-
Lorenz, E.1
Mira, J.P.2
Frees, K.L.3
Schwartz, D.A.4
-
25
-
-
0037130195
-
Toll-like receptor 4 polymorphisms and atherogenesis
-
Kiechl, S., E. Lorenz, M. Reindl, C. J. Wiedermann, F. Oberhollenzer, E. Bonora, J. Willeit, and D. A. Schwartz. 2002. Toll-like receptor 4 polymorphisms and atherogenesis. N. Engl. J. Med. 347: 185-192.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 185-192
-
-
Kiechl, S.1
Lorenz, E.2
Reindl, M.3
Wiedermann, C.J.4
Oberhollenzer, F.5
Bonora, E.6
Willeit, J.7
Schwartz, D.A.8
-
26
-
-
2542485274
-
Association between common Toll-like receptor 4 mutations and severe respiratory syncytial virus disease
-
Tal, G., A. Mandelberg, I. Dalal, K. Cesar, E. Somekh, A. Tal, A. Oron, S. Itskovich, A. Ballin, S. Houri, et al. 2004. Association between common Toll-like receptor 4 mutations and severe respiratory syncytial virus disease. J. Infect. Dis. 189: 2057-2063.
-
(2004)
J. Infect. Dis.
, vol.189
, pp. 2057-2063
-
-
Tal, G.1
Mandelberg, A.2
Dalal, I.3
Cesar, K.4
Somekh, E.5
Tal, A.6
Oron, A.7
Itskovich, S.8
Ballin, A.9
Houri, S.10
-
27
-
-
3042521641
-
299Gly polymorphism is associated with Crohn's disease and ulcerative colitis
-
299Gly polymorphism is associated with Crohn's disease and ulcerative colitis. Gut 53: 987-992.
-
(2004)
Gut
, vol.53
, pp. 987-992
-
-
Franchimont, D.1
Vermeire, S.2
El Housni, H.3
Pierik, M.4
Van Steen, K.5
Gustot, T.6
Quertinmont, E.7
Abramowicz, M.8
Van Gossum, A.9
Deviere, J.10
Rutgeerts, P.11
-
28
-
-
2942689466
-
Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: Association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis
-
Torok, H. P., J. Glas, L. Tonenchi, T. Mussack, and C. Folwaczny. 2004. Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis. Clin. Immunol. 112: 85-91.
-
(2004)
Clin. Immunol.
, vol.112
, pp. 85-91
-
-
Torok, H.P.1
Glas, J.2
Tonenchi, L.3
Mussack, T.4
Folwaczny, C.5
-
29
-
-
14544281031
-
299Gly polymorphism is associated with colonic localisation of Crohn's disease without a major role for the Saccharomyces cerevisiae mannan-LBP-CD14-TLR4 pathway
-
299Gly polymorphism is associated with colonic localisation of Crohn's disease without a major role for the Saccharomyces cerevisiae mannan-LBP-CD14-TLR4 pathway. Gut 54: 439-440.
-
(2005)
Gut
, vol.54
, pp. 439-440
-
-
Ouburg, S.1
Mallant-Hent, R.2
Crusius, J.B.3
Van Bodegraven, A.A.4
Mulder, C.J.5
Linskens, R.6
Pena, A.S.7
Morre, S.A.8
-
30
-
-
0037069791
-
Toll-like receptor 4 polymorphisms and atherogenesis
-
author reply 1978-1980
-
Cooke, G. S., S. Segal, and A. V. Hill. 2002. Toll-like receptor 4 polymorphisms and atherogenesis. N. Engl. J. Med. 347: 1978-1980; author reply 1978-1980.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 1978-1980
-
-
Cooke, G.S.1
Segal, S.2
Hill, A.V.3
-
31
-
-
1642521633
-
Polymorphisms of Toll-like receptor 2 and 4 genes in rheumatoid arthritis and systemic lupus erythematosus
-
Sanchez, E., G. Orozco, M. A. Lopez-Nevot, J. Jimenez-Alonso, and J. Martin. 2004. Polymorphisms of Toll-like receptor 2 and 4 genes in rheumatoid arthritis and systemic lupus erythematosus. Tissue Antigens 63: 54-57.
-
(2004)
Tissue Antigens
, vol.63
, pp. 54-57
-
-
Sanchez, E.1
Orozco, G.2
Lopez-Nevot, M.A.3
Jimenez-Alonso, J.4
Martin, J.5
-
32
-
-
1542283740
-
299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome
-
299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome. Arthritis Rheum. 50: 999-1001.
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 999-1001
-
-
Radstake, T.R.1
Franke, B.2
Hanssen, S.3
Netea, M.G.4
Welsing, P.5
Barrera, P.6
Joosten, L.A.7
Van Riel, P.L.8
Van Den Berg, W.B.9
-
33
-
-
4043067215
-
Association of hypo-responsive Toll-like receptor 4 variants with risk of myocardial infarction
-
Edfeldt, K., A. M. Bennet, P. Eriksson, J. Frostegard, B. Wiman, A. Hamsten, G. K. Hansson, U. de Faire, and Z. Q. Yan. 2004. Association of hypo-responsive Toll-like receptor 4 variants with risk of myocardial infarction. Eur. Heart J. 25: 1447-1453.
-
(2004)
Eur. Heart J.
, vol.25
, pp. 1447-1453
-
-
Edfeldt, K.1
Bennet, A.M.2
Eriksson, P.3
Frostegard, J.4
Wiman, B.5
Hamsten, A.6
Hansson, G.K.7
De Faire, U.8
Yan, Z.Q.9
-
34
-
-
14044259411
-
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
-
Hawn, T. R., A. Verbon, M. Janer, L. P. Zhao, B. Beutler, and A. Aderem. 2005. Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease. Proc. Natl. Acad. Sci. USA 102: 2487-2489.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2487-2489
-
-
Hawn, T.R.1
Verbon, A.2
Janer, M.3
Zhao, L.P.4
Beutler, B.5
Aderem, A.6
-
35
-
-
0037226519
-
Overexpression of CD14, TLR4, and MD-2 in HEK 293T cells does not prevent induction of in vitro endotoxin tolerance
-
Medvedev, A. E., and S. N. Vogel. 2003. Overexpression of CD14, TLR4, and MD-2 in HEK 293T cells does not prevent induction of in vitro endotoxin tolerance. J. Endotoxin Res. 9: 60-64.
-
(2003)
J. Endotoxin Res.
, vol.9
, pp. 60-64
-
-
Medvedev, A.E.1
Vogel, S.N.2
-
36
-
-
1642358911
-
Cytoplasmic domain-mediated dimerizations of Toll-like receptor 4 observed by β-lactamase enzyme fragment complementation
-
Lee, H. K., S. Dunzendorfer, and P. S. Tobias. 2004. Cytoplasmic domain-mediated dimerizations of Toll-like receptor 4 observed by β-lactamase enzyme fragment complementation. J. Biol. Chem. 279: 10564-10574.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 10564-10574
-
-
Lee, H.K.1
Dunzendorfer, S.2
Tobias, P.S.3
-
37
-
-
0014122519
-
Chemical, physical, biological properties of a lipopolysaccharide from Escherichia coli K-235
-
McIntire, F. C., H. W. Sievert, G. H. Barlow, R. A. Finley, and A. Y. Lee. 1967. Chemical, physical, biological properties of a lipopolysaccharide from Escherichia coli K-235. Biochemistry 6: 2363-2372.
-
(1967)
Biochemistry
, vol.6
, pp. 2363-2372
-
-
McIntire, F.C.1
Sievert, H.W.2
Barlow, G.H.3
Finley, R.A.4
Lee, A.Y.5
-
38
-
-
0033962913
-
Purification of respiratory syncytial virus F and G proteins
-
Roder, C., T. Krusat, K. Reimers, and H. Werchau. 2000. Purification of respiratory syncytial virus F and G proteins. J. Chromatogr. B. Biomed. Sci. Appl. 737: 97-106.
-
(2000)
J. Chromatogr. B. Biomed. Sci. Appl.
, vol.737
, pp. 97-106
-
-
Roder, C.1
Krusat, T.2
Reimers, K.3
Werchau, H.4
-
39
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov, R., P. Preston-Hurlburt, and C. A. Janeway, Jr. 1997. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388: 394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
41
-
-
8144221077
-
Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
-
Scott, P. G., P. A. McEwan, C. M. Dodd, E. M. Bergmann, P. N. Bishop, and J. Bella. 2004. Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan. Proc. Natl. Acad. Sci. USA 101: 15633-15638.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15633-15638
-
-
Scott, P.G.1
McEwan, P.A.2
Dodd, C.M.3
Bergmann, E.M.4
Bishop, P.N.5
Bella, J.6
-
42
-
-
0038263895
-
Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins
-
Barton, W. A., B. P. Liu, D. Tzvetkova, P. D. Jeffrey, A. E. Fournier, D. Sah, R. Cate, S. M. Strittmatter, and D. B. Nikolov. 2003. Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins. EMBO J. 22: 3291-3302.
-
(2003)
EMBO J.
, vol.22
, pp. 3291-3302
-
-
Barton, W.A.1
Liu, B.P.2
Tzvetkova, D.3
Jeffrey, P.D.4
Fournier, A.E.5
Sah, D.6
Cate, R.7
Strittmatter, S.M.8
Nikolov, D.B.9
-
43
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
Brunger, A. T., P. D. Adams, G. M. Clore, W. L. DeLano, P. Gros, R. W. Grosse-Kunstleve, J. S. Jiang, J. Kuszewski, M. Nilges, N. S. Pannu, et al. 1998. Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. D. 54(Pt. 5): 905-921.
-
(1998)
Acta Crystallogr. D.
, vol.54
, Issue.PART 5
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
Delano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
Jiang, J.S.7
Kuszewski, J.8
Nilges, M.9
Pannu, N.S.10
-
44
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
Nagai, Y., S. Akashi, M. Nagafuku, M. Ogata, Y. Iwakura, S. Akira, T. Kitamura, A. Kosugi, M. Kimoto, and K. Miyake. 2002. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat. Immunol. 3: 667-672.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 667-672
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
Ogata, M.4
Iwakura, Y.5
Akira, S.6
Kitamura, T.7
Kosugi, A.8
Kimoto, M.9
Miyake, K.10
-
45
-
-
0035796406
-
Molecular genetic analysis of an endotoxin nonresponder mutant cell line: A point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling
-
Schromm, A. B., E. Lien, P. Henneke, J. C. Chow, A. Yoshimura, H. Heine, E. Latz, B. G. Monks, D. A. Schwartz, K. Miyake, and D. T. Golenbock. 2001. Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling. . J. Exp. Med. 194: 79-88.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 79-88
-
-
Schromm, A.B.1
Lien, E.2
Henneke, P.3
Chow, J.C.4
Yoshimura, A.5
Heine, H.6
Latz, E.7
Monks, B.G.8
Schwartz, D.A.9
Miyake, K.10
Golenbock, D.T.11
-
46
-
-
0037033073
-
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction
-
Latz, E., A. Visintin, E. Lien, K. A. Fitzgerald, B. G. Monks, E. A. Kurt-Jones, D. T. Golenbock, and T. Espevik. 2002. Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. J. Biol. Chem. 277: 47834-47843.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47834-47843
-
-
Latz, E.1
Visintin, A.2
Lien, E.3
Fitzgerald, K.A.4
Monks, B.G.5
Kurt-Jones, E.A.6
Golenbock, D.T.7
Espevik, T.8
-
47
-
-
0035851092
-
MD-2 binds to bacterial lipopolysaccharide
-
Viriyakosol, S., P. S. Tobias, R. L. Kitchens, and T. N. Kirkland. 2001. MD-2 binds to bacterial lipopolysaccharide. J. Biol. Chem. 276: 38044-38051.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38044-38051
-
-
Viriyakosol, S.1
Tobias, P.S.2
Kitchens, R.L.3
Kirkland, T.N.4
-
48
-
-
4544250809
-
A complex of soluble MD-2 and lipopolysaccharide serves as an activating ligand for Toll-like receptor 4
-
Kennedy, M. N., G. E. Mullen, C. A. Leifer, C. Lee, A. Mazzoni, K. N. Dileepan, and D. M. Segal. 2004. A complex of soluble MD-2 and lipopolysaccharide serves as an activating ligand for Toll-like receptor 4. J. Biol. Chem. 279: 34698-34704.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 34698-34704
-
-
Kennedy, M.N.1
Mullen, G.E.2
Leifer, C.A.3
Lee, C.4
Mazzoni, A.5
Dileepan, K.N.6
Segal, D.M.7
-
49
-
-
0346850824
-
Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction
-
Visintin, A., E. Latz, B. G. Monks, T. Espevik, and D. T. Golenbock. 2003. Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction. J. Biol. Chem. 278: 48313-48320.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48313-48320
-
-
Visintin, A.1
Latz, E.2
Monks, B.G.3
Espevik, T.4
Golenbock, D.T.5
-
50
-
-
0035173628
-
CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and Taxol-inducible gene expression
-
Perera, P. Y., T. N. Mayadas, O. Takeuchi, S. Akira, M. Zaks-Zilberman, S. M. Goyert, and S. N. Vogel. 2001. CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and Taxol-inducible gene expression. J. Immunol. 166: 574-581.
-
(2001)
J. Immunol.
, vol.166
, pp. 574-581
-
-
Perera, P.Y.1
Mayadas, T.N.2
Takeuchi, O.3
Akira, S.4
Zaks-Zilberman, M.5
Goyert, S.M.6
Vogel, S.N.7
-
51
-
-
0036790341
-
Polymorphisms of TLR4: Rapid genotyping and reduced response to lipopolysaccharide of TLR4 mutant alleles
-
Schmitt, C., A. Humeny, C. M. Becker, K. Brune, and A. Pahl. 2002. Polymorphisms of TLR4: rapid genotyping and reduced response to lipopolysaccharide of TLR4 mutant alleles. Clin. Chem. 48: 1661-1667.
-
(2002)
Clin. Chem.
, vol.48
, pp. 1661-1667
-
-
Schmitt, C.1
Humeny, A.2
Becker, C.M.3
Brune, K.4
Pahl, A.5
-
52
-
-
0037465667
-
Cloning, expression and purification of three Chaperonin 60 homologues
-
Maguire, M., A. R. Coates, and B. Henderson. 2003. Cloning, expression and purification of three Chaperonin 60 homologues. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 786: 117-125.
-
(2003)
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci.
, vol.786
, pp. 117-125
-
-
Maguire, M.1
Coates, A.R.2
Henderson, B.3
-
53
-
-
0037340381
-
Chlamydia trachomatis-induced death of human spermatozoa is caused primarily by lipopolysaccharide
-
Hosseinzadeh, S., A. A. Pacey, and A. Eley. 2003. Chlamydia trachomatis-induced death of human spermatozoa is caused primarily by lipopolysaccharide. J. Med. Microbiol. 52: 193-200.
-
(2003)
J. Med. Microbiol.
, vol.52
, pp. 193-200
-
-
Hosseinzadeh, S.1
Pacey, A.A.2
Eley, A.3
-
54
-
-
0031183179
-
Outside-in signaling by lipopolysaccharide through a tailless integrin
-
Ingalls, R. R., M. A. Arnaout, and D. T. Golenbock. 1997. Outside-in signaling by lipopolysaccharide through a tailless integrin. J. Immunol. 159: 433-438.
-
(1997)
J. Immunol.
, vol.159
, pp. 433-438
-
-
Ingalls, R.R.1
Arnaout, M.A.2
Golenbock, D.T.3
-
55
-
-
3242708716
-
Endotoxin responsiveness of human airway epithelia is limited by low expression of MD-2
-
Jia, H. P., J. N. Kline, A. Penisten, M. A. Apicella, T. L. Gioannini, J. Weiss, and P. B. McCray, Jr. 2004. Endotoxin responsiveness of human airway epithelia is limited by low expression of MD-2. Am. J. Physiol. 287: L428-L437.
-
(2004)
Am. J. Physiol.
, vol.287
-
-
Jia, H.P.1
Kline, J.N.2
Penisten, A.3
Apicella, M.A.4
Gioannini, T.L.5
Weiss, J.6
McCray Jr., P.B.7
-
56
-
-
1642529500
-
Isolation of an endotoxin-MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations
-
Gioannini, T. L., A. Teghanemt, D. Zhang, N. P. Coussens, W. Dockstader, S. Ramaswamy, and J. P. Weiss. 2004. Isolation of an endotoxin-MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations. Proc. Natl. Acad. Sci. USA 101: 4186-4191.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4186-4191
-
-
Gioannini, T.L.1
Teghanemt, A.2
Zhang, D.3
Coussens, N.P.4
Dockstader, W.5
Ramaswamy, S.6
Weiss, J.P.7
-
57
-
-
23344431978
-
The molecular structure of the Toll-like receptor 3 ligand-binding domain
-
Bell, J. K., I. Botos, P. R. Hall, J. Askins, J. Shiloach, D. M. Segal, and D. R. Davies. 2005. The molecular structure of the Toll-like receptor 3 ligand-binding domain. Proc. Natl. Acad. Sci. USA 102: 10976-10980.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 10976-10980
-
-
Bell, J.K.1
Botos, I.2
Hall, P.R.3
Askins, J.4
Shiloach, J.5
Segal, D.M.6
Davies, D.R.7
-
58
-
-
23044445303
-
Crystal structure of human Toll-like receptor 3 (TLR3) ectodomain
-
Choe, J., M. S. Kelker, and I. A. Wilson. 2005. Crystal structure of human Toll-like receptor 3 (TLR3) ectodomain. Science 309: 581-585.
-
(2005)
Science
, vol.309
, pp. 581-585
-
-
Choe, J.1
Kelker, M.S.2
Wilson, I.A.3
|